Τρίτη 8 Δεκεμβρίου 2015

Relations Between the Intelligibility of Speech in Noise and Psychophysical Measures of Hearing Measured in Four Languages Using the Auditory Profile Test Battery

The aim of the present study was to determine the relations between the intelligibility of speech in noise and measures of auditory resolution, loudness recruitment, and cognitive function. The analyses were based on data published earlier as part of the presentation of the Auditory Profile, a test battery implemented in four languages. Tests of the intelligibility of speech, resolution, loudness recruitment, and lexical decision making were measured using headphones in five centers: in Germany, the Netherlands, Sweden, and the United Kingdom. Correlations and stepwise linear regression models were calculated. In sum, 72 hearing-impaired listeners aged 22 to 91 years with a broad range of hearing losses were included in the study. Several significant correlations were found with the intelligibility of speech in noise. Stepwise linear regression analyses showed that pure-tone average, age, spectral and temporal resolution, and loudness recruitment were significant predictors of the intelligibility of speech in fluctuating noise. Complex interrelationships between auditory factors and the intelligibility of speech in noise were revealed using the Auditory Profile data set in four languages. After taking into account the effects of pure-tone average and age, spectral and temporal resolution and loudness recruitment had an added value in the prediction of variation among listeners with respect to the intelligibility of speech in noise. The results of the lexical decision making test were not related to the intelligibility of speech in noise, in the population studied.



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Relations Between the Intelligibility of Speech in Noise and Psychophysical Measures of Hearing Measured in Four Languages Using the Auditory Profile Test Battery

The aim of the present study was to determine the relations between the intelligibility of speech in noise and measures of auditory resolution, loudness recruitment, and cognitive function. The analyses were based on data published earlier as part of the presentation of the Auditory Profile, a test battery implemented in four languages. Tests of the intelligibility of speech, resolution, loudness recruitment, and lexical decision making were measured using headphones in five centers: in Germany, the Netherlands, Sweden, and the United Kingdom. Correlations and stepwise linear regression models were calculated. In sum, 72 hearing-impaired listeners aged 22 to 91 years with a broad range of hearing losses were included in the study. Several significant correlations were found with the intelligibility of speech in noise. Stepwise linear regression analyses showed that pure-tone average, age, spectral and temporal resolution, and loudness recruitment were significant predictors of the intelligibility of speech in fluctuating noise. Complex interrelationships between auditory factors and the intelligibility of speech in noise were revealed using the Auditory Profile data set in four languages. After taking into account the effects of pure-tone average and age, spectral and temporal resolution and loudness recruitment had an added value in the prediction of variation among listeners with respect to the intelligibility of speech in noise. The results of the lexical decision making test were not related to the intelligibility of speech in noise, in the population studied.



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Relations Between the Intelligibility of Speech in Noise and Psychophysical Measures of Hearing Measured in Four Languages Using the Auditory Profile Test Battery

The aim of the present study was to determine the relations between the intelligibility of speech in noise and measures of auditory resolution, loudness recruitment, and cognitive function. The analyses were based on data published earlier as part of the presentation of the Auditory Profile, a test battery implemented in four languages. Tests of the intelligibility of speech, resolution, loudness recruitment, and lexical decision making were measured using headphones in five centers: in Germany, the Netherlands, Sweden, and the United Kingdom. Correlations and stepwise linear regression models were calculated. In sum, 72 hearing-impaired listeners aged 22 to 91 years with a broad range of hearing losses were included in the study. Several significant correlations were found with the intelligibility of speech in noise. Stepwise linear regression analyses showed that pure-tone average, age, spectral and temporal resolution, and loudness recruitment were significant predictors of the intelligibility of speech in fluctuating noise. Complex interrelationships between auditory factors and the intelligibility of speech in noise were revealed using the Auditory Profile data set in four languages. After taking into account the effects of pure-tone average and age, spectral and temporal resolution and loudness recruitment had an added value in the prediction of variation among listeners with respect to the intelligibility of speech in noise. The results of the lexical decision making test were not related to the intelligibility of speech in noise, in the population studied.



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A Quasi-Universal Nonword Repetition Task as a Diagnostic Tool for Bilingual Children Learning Dutch as a Second Language

Purpose
This study evaluated a newly developed quasi-universal nonword repetition task (Q-U NWRT) as a diagnostic tool for bilingual children with language impairment (LI) who have Dutch as a 2nd language. The Q-U NWRT was designed to be minimally influenced by knowledge of 1 specific language in contrast to a language-specific NWRT with which it was compared.
Method
One hundred twenty monolingual and bilingual children with and without LI participated (30 per group). A mixed-design analysis of variance was used to investigate the effects of LI and bilingualism on the NWRTs. Receiver operating characteristic analyses were conducted to evaluate the instruments' diagnostic value.
Results
Large negative effects of LI were found on both NWRTs, whereas negative effects of bilingualism only occurred on the language-specific NWRT. Both instruments had high clinical accuracy in the monolingual group, but only the Q-U NWRT had high clinical accuracy in the bilingual group.
Conclusions
This study indicates that the Q-U NWRT is a promising diagnostic tool to help identify LI in bilingual children learning Dutch as a 2nd language. The instrument was clinically accurate in both a monolingual and bilingual group of children and seems better able to disentangle LI from language disadvantage than more language-specific measures.

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A Quasi-Universal Nonword Repetition Task as a Diagnostic Tool for Bilingual Children Learning Dutch as a Second Language

Purpose
This study evaluated a newly developed quasi-universal nonword repetition task (Q-U NWRT) as a diagnostic tool for bilingual children with language impairment (LI) who have Dutch as a 2nd language. The Q-U NWRT was designed to be minimally influenced by knowledge of 1 specific language in contrast to a language-specific NWRT with which it was compared.
Method
One hundred twenty monolingual and bilingual children with and without LI participated (30 per group). A mixed-design analysis of variance was used to investigate the effects of LI and bilingualism on the NWRTs. Receiver operating characteristic analyses were conducted to evaluate the instruments' diagnostic value.
Results
Large negative effects of LI were found on both NWRTs, whereas negative effects of bilingualism only occurred on the language-specific NWRT. Both instruments had high clinical accuracy in the monolingual group, but only the Q-U NWRT had high clinical accuracy in the bilingual group.
Conclusions
This study indicates that the Q-U NWRT is a promising diagnostic tool to help identify LI in bilingual children learning Dutch as a 2nd language. The instrument was clinically accurate in both a monolingual and bilingual group of children and seems better able to disentangle LI from language disadvantage than more language-specific measures.

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A Quasi-Universal Nonword Repetition Task as a Diagnostic Tool for Bilingual Children Learning Dutch as a Second Language

Purpose
This study evaluated a newly developed quasi-universal nonword repetition task (Q-U NWRT) as a diagnostic tool for bilingual children with language impairment (LI) who have Dutch as a 2nd language. The Q-U NWRT was designed to be minimally influenced by knowledge of 1 specific language in contrast to a language-specific NWRT with which it was compared.
Method
One hundred twenty monolingual and bilingual children with and without LI participated (30 per group). A mixed-design analysis of variance was used to investigate the effects of LI and bilingualism on the NWRTs. Receiver operating characteristic analyses were conducted to evaluate the instruments' diagnostic value.
Results
Large negative effects of LI were found on both NWRTs, whereas negative effects of bilingualism only occurred on the language-specific NWRT. Both instruments had high clinical accuracy in the monolingual group, but only the Q-U NWRT had high clinical accuracy in the bilingual group.
Conclusions
This study indicates that the Q-U NWRT is a promising diagnostic tool to help identify LI in bilingual children learning Dutch as a 2nd language. The instrument was clinically accurate in both a monolingual and bilingual group of children and seems better able to disentangle LI from language disadvantage than more language-specific measures.

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Voice Disorder Management Competencies: A Survey of School-Based Speech-Language Pathologists in Nebraska

Purpose
The purpose of this survey was to determine the self-perceived competence levels in voice disorders of practicing school-based speech-language pathologists (SLPs) and identify correlated variables.
Method
Participants were 153 master's level, school-based SLPs with a Nebraska teaching certificate and/or licensure who completed a survey, including demographic information and a 25-item voice disorders competency checklist.
Results
Findings indicated school-based SLPs did not feel particularly competent in their ability to assess and treat students with voice disorders. Only 1 response mean was higher than a “moderately competent” level. All other item means were at or below this level. Four correlations indicated positive associations with SLPs' overall self-perceived competence levels: number of continuing education activities related to voice disorders, number of clients with voice disorders in the last 3 months, percentage of time spent with clients who have voice disorders, and feelings of preparation in the area of voice disorders immediately after academic program completion. Informal comparisons to medically based SLP respondents (n = 22) were included.
Conclusion
School-based SLPs' competence perceptions with voice disorders are consistent with the minimal levels of competence reported for other underserved or low-incidence populations. Pursuing continuing education in voice disorders is recommended at the same time as access to the population becomes available.

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Voice Disorder Management Competencies: A Survey of School-Based Speech-Language Pathologists in Nebraska

Purpose
The purpose of this survey was to determine the self-perceived competence levels in voice disorders of practicing school-based speech-language pathologists (SLPs) and identify correlated variables.
Method
Participants were 153 master's level, school-based SLPs with a Nebraska teaching certificate and/or licensure who completed a survey, including demographic information and a 25-item voice disorders competency checklist.
Results
Findings indicated school-based SLPs did not feel particularly competent in their ability to assess and treat students with voice disorders. Only 1 response mean was higher than a “moderately competent” level. All other item means were at or below this level. Four correlations indicated positive associations with SLPs' overall self-perceived competence levels: number of continuing education activities related to voice disorders, number of clients with voice disorders in the last 3 months, percentage of time spent with clients who have voice disorders, and feelings of preparation in the area of voice disorders immediately after academic program completion. Informal comparisons to medically based SLP respondents (n = 22) were included.
Conclusion
School-based SLPs' competence perceptions with voice disorders are consistent with the minimal levels of competence reported for other underserved or low-incidence populations. Pursuing continuing education in voice disorders is recommended at the same time as access to the population becomes available.

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Voice Disorder Management Competencies: A Survey of School-Based Speech-Language Pathologists in Nebraska

Purpose
The purpose of this survey was to determine the self-perceived competence levels in voice disorders of practicing school-based speech-language pathologists (SLPs) and identify correlated variables.
Method
Participants were 153 master's level, school-based SLPs with a Nebraska teaching certificate and/or licensure who completed a survey, including demographic information and a 25-item voice disorders competency checklist.
Results
Findings indicated school-based SLPs did not feel particularly competent in their ability to assess and treat students with voice disorders. Only 1 response mean was higher than a “moderately competent” level. All other item means were at or below this level. Four correlations indicated positive associations with SLPs' overall self-perceived competence levels: number of continuing education activities related to voice disorders, number of clients with voice disorders in the last 3 months, percentage of time spent with clients who have voice disorders, and feelings of preparation in the area of voice disorders immediately after academic program completion. Informal comparisons to medically based SLP respondents (n = 22) were included.
Conclusion
School-based SLPs' competence perceptions with voice disorders are consistent with the minimal levels of competence reported for other underserved or low-incidence populations. Pursuing continuing education in voice disorders is recommended at the same time as access to the population becomes available.

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Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.

Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.:

Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.

Otol Neurotol. 2015 Nov 21;

Authors: Rahne T, Schilde S, Seiwerth I, Radetzki F, Stoevesandt D, Plontke SK

Abstract

OBJECTIVES: Bone-conduction implants (BCI) are available for adults and children who are aged 5 years or more. Because a transcutaneous bone-conduction implant introduced in 2013 does not completely fit into all adult mastoids, we investigated mastoid dimensions and the possibility of fitting the implant in children.

DESIGN: Computed tomography scans of 151 mastoids from 80 children and young adolescents from the age of 5 months to 20 years and 52 control mastoids from 33 adults were retrospectively analyzed. After three-dimensional reconstruction, mastoid volume was measured. The chances of fitting the Bonebridge or a novel BCI were determined as a function of age. Implant diameter and implantation depths were virtually varied to identify the most advantageous dimensions for reducing the minimum age for implantation.

RESULTS: Mastoid volume increased to 13.8 ml in female and 16.4 ml in male adult mastoids at ages 18.9 years (male) and 19.0 years (female). Without compromising the middle fossa dura or the sinus and without lifts, the Bonebridge implant fit in 81% of male adult mastoids and 77% of the female adult mastoids. For children, the 50% chance of fitting a Bonebridge in the mastoids was reached at age 12 years; with a protrusion of 4 mm (4-mm lifts), this age was reduced to >6 years. The novel BCI fit in 100% of male and 94% of female adult mastoids.

CONCLUSIONS: Casing diameter is the most limiting factor for Bonebridge implantation in children. A modified implant casing with a truncated cone and reduced diameter and volume would increase the number of hearing impaired children who can be rehabilitated with a Bonebridge implant. Radiological planning for Bonebridge implantation is necessary in all children.

PMID: 26641261 [PubMed - as supplied by publisher]

TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.

TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.:

TLR4 drives the pathogenesis of acquired cholesteatoma by promoting local inflammation and bone destruction.

Sci Rep. 2015;5:16683

Authors: Si Y, Chen YB, Chen SJ, Zheng YQ, Liu X, Liu Y, Jiang HL, Xu G, Li ZH, Huang QH, Xiong H, Zhang ZG

Abstract

Acquired cholesteatoma is a chronic inflammatory disease characterized by both hyperkeratinized squamous epithelial overgrowth and bone destruction. Toll-like receptor (TLR) activation and subsequent inflammatory cytokine production are closely associated with inflammatory bone disease. However, the expression and function of TLRs in cholesteatoma remain unclear.We observed inflammatory cell infiltration of the matrix and prematrix of human acquired cholesteatoma, as well as dramatically increased expression of TLR4 and the pro-inflammatory cytokines TNF-α and IL-1β. TLR2 exhibited an up-regulation that was not statistically significant. TLR4 expression in human acquired cholesteatoma correlated with disease severity; the number of TLR4-positive cells increased with an increased degree of cholesteatoma, invasion, bone destruction, and hearing loss. Moreover, TLR4 deficiency was protective against experimental acquired cholesteatoma-driven bone destruction and hearing loss, as it reduced local TNF-α and IL-1β expression and impaired osteoclast formation by decreasing expression of the osteoclast effectors receptor activator of nuclear factor (NF)-κB ligand (RANKL) and tartrate-resistant acid phosphatase (TRAP). TLR2 deficiency did not relieve disease severity, inflammatory responses, or osteoclast formation. Moreover, neither TLR2 nor TLR4 deficiency had an effect on antimicrobial peptides, inducible iNOS,BD-2 expression or bacterial clearance. Therefore, TLR4 may promote cholesteatoma-induced bone destruction and deafness by enhancing inflammatory responses and osteoclastogenesis.

PMID: 26639190 [PubMed - in process]

Level dependence of the nonlinear-distortion component of distortion-product otoacoustic emissions in humansa)

Level dependence of the nonlinear-distortion component of distortion-product otoacoustic emissions in humansa):

Distortion-product otoacoustic emissions (DPOAEs) emerge when presenting two primary tones with different frequencies f1 and f2 to the cochlea and are commonly used in diagnosis and research to evaluate the functional state of the cochlea. Optimal primary-tone stimulus levels accounting for the different level dependencies of the traveling-wave amplitudes of the two primary tones near the f2-tonotopic place on the basilar membrane are often used to maximize DPOAE amplitudes. However, parameters defining the optimal levels can be affected by wave interference between the nonlinear-distortion and coherent-reflection components of the DPOAE. Here, the components were separated in the time domain using a pulsed stimulus paradigm and optimal levels determined. Based on the amplitude dependence of the nonlinear-distortion components on primary-tone stimulus levels, level parameters yielding maximum DPOAE amplitudes were derived for six normal-hearing adults and compared to data recorded with continuous two-tone stimulation. The level parameters resulting from analysis of the nonlinear-distortion components show dependence on stimulus frequency and small standard deviations. DPOAE input/output functions derived for optimal levels exhibit larger slopes, wider dynamic range and less variability across subjects than those derived for conventional stimulus and analysis conditions, potentially increasing their reliability and sensitivity for assessing cochlea function.

Audiology Key Performance Indicators in an ENT Practice

The Numbers Don't Lie: Audiology Key Performance Indicators in an ENT Practice: Historically, audiologists did not have the capability to systematically measure any part of their business. Sure, they had a general idea of their return rate, gross margin or annual revenue, but oftentimes it was more of a guess than a cold, hard fact. The daily operation of their practice was left completely to intuition and chance. In fact, leaving the performance of the business to chance was a standard business practice in many practices.Today, due mainly to relatively inexpensive, web-based office management systems, audiologists have a virtual arsenal of data at their fingertips. With a swipe of a finger on their smartphone or the click of a mouse on their laptop, an audiologist can gauge the effectiveness of their latest marketing campaign, or the need to fill their schedule with more patients. In many ways, this ocean of data reflects both a surge in technical sophistication driven by the ever-improving microchip as well as a society preoccupied with lists and numbers. Charts, graphs, stats and other types of numbers are all around us. From tracking your favorite fantasy sports star to following the popularity of your last Tweet, there is no escaping the sheer breadth and depth of data, all of it readily available at our fingertips. Nevertheless, based on our experiences, many audiologists, who have access to heaps of data about their practice either chose to ignore it, or fail to use it to make decisions about their business. Perhaps a failure to act on the abundance of this data is a side effect of having too much information. An example of just how much data can be loaded onto a single dashboard is shown in Figure 1.

With a Bone-anchored Hearing Aid, One Good Ear Helps the Other

With a Bone-anchored Hearing Aid, One Good Ear Helps the Other:

In early June 2014, Steve Blatt was riding his motorcycle to work along the same route he’d used for nearly 40 years.  It was raining, and when his front tire hit an uneven spot in the road, his bike slid out from under him.  He did two somersaults through the air and lost his helmet.  When he hit the ground, he suffered a transverse fracture through his right temporal bone – the hardest bone in the body – a complex structure that houses the cochlear and vestibular end organs, the facial nerve, the carotid artery and the jugular vein.  Blatt was rushed to the Level I Texas Trauma Institute at Memorial Hermann-Texas Medical Center as a full code with a traumatic brain injury, mandibular fracture and three broken ribs.  After being stabilized by the trauma team, he was admitted to the otorhinolaryngology service under the care of Ibrahim “Trey” Alava III, MD.

“Steve couldn’t hear out of his right ear and reported dizziness with a sensation of spinning,” says Dr. Alava, an assistant professor in the Department of Otorhinolaryngology-Head and Neck Surgery at UTHealth Medical School.  “A portion of the right mandible under the temporal bone had been fractured, and he was bleeding from his right ear.”   Two days later, Blatt, still hospitalized, developed facial nerve paralysis as a result of swelling in the nerve canal. Dr. Alava prescribed steroids to treat the paralysis, which resolved over time.   After a five-day hospitalization, Blatt continued in follow-up with Dr. Alava for head and ear trauma. A few weeks later, the otolaryngologist referred his patient to UTHealth Audiology, where Allison Boggess, Au.D., performed a comprehensive hearing assessment and evaluation using videonystagmography.

“We knew that conventional hearing aids wouldn’t help his deficit,” Dr. Alava says. “Instead, we recommended a bone-anchored hearing aid (BAHA) to route the sound from his non-hearing right ear to his good left ear.”  BAHAs use the skull’s ability to transmit sound to the ear with good hearing.  The surgeon implants the bone-anchored implant, which picks up sounds through an external, magnetically attached microphone/processor that converts the sound into vibrations. The vibrations are transmitted through the skin to the skull as recognizable sounds.



Bone-anchored hearing aids transfer sound from the patient’s poorly functioning ear to the opposite ear with good hearing. The device transforms sound energy to vibrations transmitted through the skull to the normal cochlea in the hearing ear.


Bone-anchored hearing aids transfer sound from the patient’s poorly functioning ear to the opposite ear with good hearing. The device transforms sound energy to vibrations transmitted through the skull to the normal cochlea in the hearing ear.
In an uncomplicated day surgery, Dr. Alava made an incision behind Blatt’s non-hearing ear, drilled two wells to allow the implant to rest flush to the skull and screwed in the magnetized implant before closing the incision. “The microphone has a magnetic base plate that allows it to attach to the implant and be removed,” he says. “Steve wears the microphone on the outside and as it vibrates the skull, he can perceive sounds that come from the right through his left ear,” Dr. Alava says.

To compensate for his spatial hearing loss, Blatt underwent vestibular rehabilitation at TIRR Memorial Hermann Outpatient Rehabilitation at the Kirby Glen Center, where therapists developed a comprehensive plan to reduce his symptoms and improve his balance.  During an intensive, custom-designed four-month program, he regained much of the physical function he had lost, and continues his recovery.   “It takes a while to get used to the magnet and microphone,” Blatt says.  “The microphone looks like a Bluetooth headset attached to the scalp behind my right ear. It has a volume control, and the magnet has five or six different strengths that have to be adjusted regularly.  I go in to see the audiologist, she connects it to a computer and tweaks the programming or installs an upgrade.”

Dr. Alava is still seeing Blatt in follow-up for balance issues.  “Even though a patient may lose his vestibular function on one side, there is a compensation mechanism because of the brain’s plasticity. They learn to compensate for the loss over time,” he says.

Blatt considers himself lucky to be alive. “I’ve always been an advocate for helmets and motorcycle safety,” he says. “The accident itself and losing my helmet was one of those one in a million things. Allie is a great audiologist, and Trey is a great doctor. I see her regularly, and he’s always available by text when I have a question.  The hearing aid has given me something like 10 to 15 percent hearing in my right ear.  That’s a whole lot better than zero.”

The post With a Bone-anchored Hearing Aid, One Good Ear Helps the Other appeared first on Department of Otorhinolaryngology.

Effect of Sensorineural Hearing Loss on Neurocognitive Functioning in Pediatric Brain Tumor Survivors

Effect of Sensorineural Hearing Loss on Neurocognitive Functioning in Pediatric Brain Tumor Survivors:



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Background

Intensified therapy with platinum-based regimens for pediatric brain tumors has dramatically increased the number of pediatric brain tumor survivors (PBTS) but frequently causes permanent sensorineural hearing loss (SNHL). Although neurocognitive decline in PBTS is known to be associated with radiation therapy (RT), SNHL represents a potential additional contributor whose long-term impact has yet to be fully determined.

Methods

The neurocognitive impact of significant SNHL (Chang scale ≥ 2b) in PBTS was assessed through a retrospective cohort study of audiograms and neurocognitive testing. Scores for neurocognitive domains and subtest task performance were analyzed to identify specific strengths and weakness for PBTS with SNHL.

Results

In a cohort of PBTS (n = 58) treated with platinum therapy, significant SNHL was identified in more than half (55%, n = 32/58), of which the majority required hearing aids (72%, 23/32). RT exposure was approximately evenly divided between those with and without SNHL. PBTS were 6.7 ± 0.6 and 11.3 ± 0.7 years old at diagnosis and neurocognitive testing, respectively. In multivariate analyses adjusted for RT dose, SNHL was independently associated with deficits in intelligence, executive function, and verbal reasoning skills. Subtests revealed PBTS with SNHL to have poor learning efficiency but intact memory and information acquisition.

Conclusions

SNHL in PBTS increases the risk for severe therapy-related intellectual and neurocognitive deficits. Additional prospective investigation in malignant brain tumors is necessary to validate these findings through integration of audiology and neurocognitive assessments and to identify appropriate strategies for neurocognitive screening and rehabilitation specific to PBTS with and without SNHL.

Genetic mutation susceptibility of hearing loss in child with severe neonatal jaundice

Genetic mutation susceptibility of hearing loss in child with severe neonatal jaundice: 2015-11-05T17-39-20Z

Source: Rawal Medical Journal

Farah Dayana Zahedi, Roslenda Abdul Rahman, Adli Ali, Asma Abdullah.


This case report demonstrates a case of 5-year-old non-syndromic Malay boy who passed the hearing screening test however he was confirmed has bilateral profound sensorineural hearing loss diagnosed at 3 months of age by brain stem evoked response (BSER). He has background history of severe neonatal jaundice and male siblings of hearing impairment.
The antenatal and birth history was uneventful apart from maternal hypothyroidism. His other two elder brothers have bilateral sensorineural hearing loss and history of severe neonatal jaundice as well. The ear examinations, computed tomography scan and magnetic resonance imaging revealed normal findings. Right sided cochlear implantation was done at the age of 3 years old and he is still under audiology follow-up.
Conclusion: Genetic studies are important to determine the cause of genetic mutation in susceptibility to hearing impairment that run in his family after severe neonatal jaundice. Those baby with risk of developing hearing loss required diagnostic hearing assessment.

Current-reported outcome domains in studies of adults with a focus on the treatment of tinnitus: protocol for a systematic review

Current-reported outcome domains in studies of adults with a focus on the treatment of tinnitus: protocol for a systematic review: Introduction

In Europe alone, over 70 million people experience tinnitus. Despite its considerable socioeconomic relevance, progress in developing successful treatments has been limited. Clinical effectiveness is judged according to change in primary outcome measures, but because tinnitus is a subjective condition, the definition of outcomes is challenging and it remains unclear which distinct aspects of tinnitus (ie, ‘domains’) are most relevant for assessment. The development of a minimum outcome reporting standard would go a long way towards addressing these problems. In 2006, a consensus meeting recommended using 1 of 4 questionnaires for tinnitus severity as an outcome in clinical trials, in part because of availability in different language translations. Our initiative takes an approach motivated by clinimetrics, first by determining what to measure before seeking to determine how to measure it. Agreeing on the domains that contribute to tinnitus severity (ie, ‘what’) is the first step towards achieving a minimum outcome reporting standard for tinnitus that has been reached via a methodologically rigorous and transparent process.

Methods and analysis

Deciding what should be the core set of outcomes requires a great deal of discussion and so lends itself well to international effort. This protocol lays out the first-step methodology in defining a Core Domain Set for clinical trials of tinnitus by establishing existing knowledge and practice with respect to which outcome domains have been measured and which instruments used in recent registered and published clinical trials.

Ethics and dissemination

No ethical issues are foreseen. Findings will be reported at national and international ear, nose and throat (ENT) and audiology conferences and in a peer-reviewed journal, using PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analysis) guidelines.

Trial registration number

The systematic review protocol is registered on PROSPERO (International Prospective Register of Systematic Reviews): CRD42015017525.

Wireless Endoscope Camera

Firefly Passes Milestone: Wireless Endoscope Camera Now in 25 Countries:

November 3rd 2015 – Returning for another year at Medica, Firefly brings its popular DE1250 Wireless Endoscope Camera back to Dusseldorf. The Boston based company, which has been selling its award winning Wireless Video Otoscope and Wireless Digital Dermatoscope cameras to some of the most prestigious organizations around the globe, is now being distributed in over 25 countries, and the number of medical professionals who are bringing the Firefly system on board continues to grow.

Introduced at Medica 2014, the Firefly Wireless Endoscope Camera is one of the highest quality and most economical tools available to document endoscopic procedures, educate patients on why they need to move forward with various procedures, and educate medical students in a clinical setting. While the Wireless Endoscope Camera was designed to help improve endoscopic procedures, it also acts as a powerful documentation tool for electronic medical records (EMR/EHR). Firefly’s CEO, Kapriel Karagozyan, commented on the company’s development philosophy –

“As with all our cameras, we design every product with the doctor and patient in mind. The cameras need to be easy to use, show immediate value, and must be affordably priced. In the case of the DE1250 Wireless Endo-Camera, we also thought of a third party – The electronic medical records software. Images and video from our devices can be easily imported or transferred into standard EMR/EHR platforms. This has broadened the appeal of our products to a wider audience.”

Firefly Global is in the business of making high quality, affordable, video otoscopes, digital dermatoscopes, and endoscope cameras for organizations worldwide. Firefly wireless and wired cameras are small, easy to use and standards-based, making integration with video conferencing solutions quick and easy. Already popular in Ear-Nose-Throat, Primary Care, Audiology, Telemedicine and Dermatology, the number of practices using Firefly are multiplying rapidly. The Firefly Wireless Video Otoscope, Wireless Digital Dermatoscope, and Wireless Endoscope Camera can be found at Medica in Booth 16/D32-15 in the US Pavilion, from November 16th to the 19th.

What Can We Learn about Auditory Processing from Adult Hearing Questionnaires?

What Can We Learn about Auditory Processing from Adult Hearing Questionnaires?:

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What Can We Learn about Auditory Processing from Adult Hearing Questionnaires?

J Am Acad Audiol. 2015 Nov-Dec;26(10):824-37

Authors: Bamiou DE, Iliadou VV, Zanchetta S, Spyridakou C

Abstract

BACKGROUND: Questionnaires addressing auditory disability may identify and quantify specific symptoms in adult patients with listening difficulties.

PURPOSE: (1) To assess validity of the Speech, Spatial, and Qualities of Hearing Scale (SSQ), the (Modified) Amsterdam Inventory for Auditory Disability (mAIAD), and the Hyperacusis Questionnaire (HYP) in adult patients experiencing listening difficulties in the presence of a normal audiogram. (2) To examine which individual questionnaire items give the worse scores in clinical participants with an auditory processing disorder (APD).

RESEARCH DESIGN: A prospective correlational analysis study.

STUDY SAMPLE: Clinical participants (N = 58) referred for assessment because of listening difficulties in the presence of normal audiometric thresholds to audiology/ear, nose, and throat or audiovestibular medicine clinics. Normal control participants (N = 30).

DATA COLLECTION AND ANALYSIS: The mAIAD, HYP, and the SSQ were administered to a clinical population of nonneurological adults who were referred for auditory processing (AP) assessment because of hearing complaints, in the presence of normal audiogram and cochlear function, and to a sample of age-matched normal-hearing controls, before the AP testing. Clinical participants with abnormal results in at least one ear and in at least two tests of AP (and at least one of these tests to be nonspeech) were classified as clinical APD (N = 39), and the remaining (16 of whom had a single test abnormality) as clinical non-APD (N = 19).

RESULTS: The SSQ correlated strongly with the mAIAD and the HYP, and correlation was similar within the clinical group and the normal controls. All questionnaire total scores and subscores (except sound distinction of mAIAD) were significantly worse in the clinical APD versus the normal group, while questionnaire total scores and most subscores indicated greater listening difficulties for the clinical non-APD versus the normal subgroups. Overall, the clinical non-APD group tended to give better scores than the APD in all questionnaires administered. Correlation was strong for the worse-ear gaps-in-noise threshold with the SSQ, mAIAD, and HYP; strong to moderate for the speech in babble and left-ear dichotic digit test scores (at p < 0.01); and weak to moderate for the remaining AP tests except the frequency pattern test that did not correlate. The worse-scored items in all three questionnaires concerned speech-in-noise questions. This is similar to worse-scored items by hearing-impaired participants as reported in the literature. Worse-scored items of the clinical group also included quality aspects of listening questions from the SSQ, which most likely pertain to cognitive aspects of listening, such as ability to ignore other sounds and listening effort.

CONCLUSIONS: Hearing questionnaires may help assess symptoms of adults with APD. The listening difficulties and needs of adults with APD to some extent overlap with those of hearing-impaired listeners, but there are significant differences. The correlation of the gaps-in-noise and duration pattern (but not frequency pattern) tests with the questionnaire scores indicates that temporal processing deficits may play an important role in clinical presentation.

PMID: 26554488 [PubMed - in process]

Benefits of Nonlinear Frequency Compression in Adult Hearing Aid Users.

Benefits of Nonlinear Frequency Compression in Adult Hearing Aid Users.:

Related Articles
Benefits of Nonlinear Frequency Compression in Adult Hearing Aid Users.

J Am Acad Audiol. 2015 Nov-Dec;26(10):838-55

Authors: Kokx-Ryan M, Cohen J, Cord MT, Walden TC, Makashay MJ, Sheffield BM, Brungart DS

Abstract

BACKGROUND: Frequency-lowering (FL) algorithms are an alternative method of providing access to high-frequency speech cues. There is currently a lack of independent research addressing: (1) what functional, measureable benefits FL provides; (2) which, if any, FL algorithm provides the maximum benefit, (3) how to clinically program algorithms, and (4) how to verify algorithm settings.

PURPOSE: Two experiments were included in this study. The purpose of Experiment 1 was to (1) determine if a commercially available nonlinear frequency compression (NLFC) algorithm provides benefit as measured by improved speech recognition in noise when fit and verified using standard clinical procedures; and (2) evaluate the impact of acclimatization. The purpose of Experiment 2 was to (1) evaluate the benefit of using enhanced verification procedures to systematically determine the optimal application of a prototype NLFC algorithm, and (2) determine if the optimized prototype NLFC settings provide benefit as measured by improved speech recognition in quiet and in noise.

RESEARCH DESIGN: A single-blind, within-participant repeated measures design in which participants served as their own controls.

STUDY SAMPLE: Experiment 1 included 26 participants with a mean age of 68.3 yr and Experiment 2 included 37 participants with a mean age of 68.8 yr. Participants were recruited from the Audiology and Speech Pathology Center at Walter Reed National Military Medical Center in Bethesda, MD.

INTERVENTION: Participants in Experiment 1 wore bilateral commercially available hearing aids fit using standard clinical procedures and clinician expertise. Participants in Experiment 2 wore a single prototype hearing aid for which FL settings were systematically examined to determine the optimum application. In each experiment, FL-On versus FL-Off settings were examined in a variety of listening situations to determine benefit and possible implications.

DATA COLLECTION AND ANALYSIS: In Experiment 1, speech recognition measures using the QuickSIN and Modified Rhyme Test stimuli were obtained at initial bilateral fitting and 3-5 weeks later during a follow-up visit. In Experiment 2, Modified Rhyme Test, /sə/, /∫ə/ consonant discrimination task, and dual-task cognitive load speech recognition performance measures were conducted. Participants in Experiment 2 received four different systematic hearing aid programs during an initial visit and speech recognition data were collected over 2-3 follow-up sessions.

RESULTS: Some adults with hearing loss obtained small-to-moderate benefits from implementation of FL, while others maintained performance without detriment in both experiments. There was no significant difference among FL-On settings systematically obtained in Experiment 2. There was a modest but significant age effect in listeners of both experiments that indicated older listeners (>65 yr) might benefit more on average from FL than younger listeners. In addition, there were reliable improvements in the intelligibility of the phonemes /ŋ/ and /b/ for both groups, and /ð/ for older listeners from the FL in both experiments.

CONCLUSIONS: Although the optimum settings, application, and benefits of FL remain unclear at this time, there does not seem to be degradation in listener performance when FL is activated. The benefits of FL should be explored in older adult (>65 yr) listeners, as they tended to benefit more from FL applications.

PMID: 26554489 [PubMed - in process]

Construct Validity of the Ecological Momentary Assessment in Audiology Research.

Construct Validity of the Ecological Momentary Assessment in Audiology Research.:

Related Articles
Construct Validity of the Ecological Momentary Assessment in Audiology Research.

J Am Acad Audiol. 2015 Nov-Dec;26(10):872-84

Authors: Wu YH, Stangl E, Zhang X, Bentler RA

Abstract

BACKGROUND: Ecological momentary assessment (EMA) is a methodology involving repeated assessments/surveys to collect data describing respondents' current or very recent experiences and related contexts in their natural environments. The use of EMA in audiology research is growing.

PURPOSE: This study examined the construct validity (i.e., the degree to which a measurement reflects what it is intended to measure) of EMA in terms of measuring speech understanding and related listening context. Experiment 1 investigated the extent to which individuals can accurately report their speech recognition performance and characterize the listening context in controlled environments. Experiment 2 investigated whether the data aggregated across multiple EMA surveys conducted in uncontrolled, real-world environments would reveal a valid pattern that was consistent with the established relationships between speech understanding, hearing aid use, listening context, and lifestyle.

RESEARCH DESIGN: This is an observational study.

STUDY SAMPLE: Twelve and twenty-seven adults with hearing impairment participated in Experiments 1 and 2, respectively.

DATA COLLECTION AND ANALYSIS: In the laboratory testing of Experiment 1, participants estimated their speech recognition performance in settings wherein the signal-to-noise ratio was fixed or constantly varied across sentences. In the field testing the participants reported the listening context (e.g., noisiness level) of several semicontrolled real-world conversations. Their reports were compared to (1) the context described by normal-hearing observers and (2) the background noise level measured using a sound level meter. In Experiment 2, participants repeatedly reported the degree of speech understanding, hearing aid use, and listening context using paper-and-pencil journals in their natural environments for 1 week. They also carried noise dosimeters to measure the sound level. The associations between (1) speech understanding, hearing aid use, and listening context, (2) dosimeter sound level and self-reported noisiness level, and (3) dosimeter data and lifestyle quantified using the journals were examined.

RESULTS: For Experiment 1, the reported and measured speech recognition scores were highly correlated across all test conditions (r = 0.94 to 0.97). The field testing results revealed that most listening context properties reported by the participants were highly consistent with those described by the observers (74-95% consistency), except for noisiness rating (58%). Nevertheless, higher noisiness rating was associated with higher background noise level. For Experiment 2, the EMA results revealed several associations: better speech understanding was associated with the use of hearing aids, front-located speech, and lower dosimeter sound level; higher noisiness rating was associated with higher dosimeter sound level; listeners with more diverse lifestyles tended to have higher dosimeter sound levels.

CONCLUSIONS: Adults with hearing impairment were able to report their listening experiences, such as speech understanding, and characterize listening context in controlled environments with reasonable accuracy. The pattern of the data aggregated across multiple EMA surveys conducted in a wide range of uncontrolled real-world environment was consistent with the established knowledge in audiology. The two experiments suggested that, regarding speech understanding and related listening contexts, EMA reflects what it is intended to measure, supporting its construct validity in audiology research.

PMID: 26554491 [PubMed - in process]

Current-reported outcome domains in studies of adults with a focus on the treatment of tinnitus: protocol for a systematic review.

Current-reported outcome domains in studies of adults with a focus on the treatment of tinnitus: protocol for a systematic review.:

Current-reported outcome domains in studies of adults with a focus on the treatment of tinnitus: protocol for a systematic review.

BMJ Open. 2015;5(11):e009091

Authors: Hall DA, Szczepek AJ, Kennedy V, Haider H

Abstract

INTRODUCTION: In Europe alone, over 70 million people experience tinnitus. Despite its considerable socioeconomic relevance, progress in developing successful treatments has been limited. Clinical effectiveness is judged according to change in primary outcome measures, but because tinnitus is a subjective condition, the definition of outcomes is challenging and it remains unclear which distinct aspects of tinnitus (ie, 'domains') are most relevant for assessment. The development of a minimum outcome reporting standard would go a long way towards addressing these problems. In 2006, a consensus meeting recommended using 1 of 4 questionnaires for tinnitus severity as an outcome in clinical trials, in part because of availability in different language translations. Our initiative takes an approach motivated by clinimetrics, first by determining what to measure before seeking to determine how to measure it. Agreeing on the domains that contribute to tinnitus severity (ie, 'what') is the first step towards achieving a minimum outcome reporting standard for tinnitus that has been reached via a methodologically rigorous and transparent process.

METHODS AND ANALYSIS: Deciding what should be the core set of outcomes requires a great deal of discussion and so lends itself well to international effort. This protocol lays out the first-step methodology in defining a Core Domain Set for clinical trials of tinnitus by establishing existing knowledge and practice with respect to which outcome domains have been measured and which instruments used in recent registered and published clinical trials.

ETHICS AND DISSEMINATION: No ethical issues are foreseen. Findings will be reported at national and international ear, nose and throat (ENT) and audiology conferences and in a peer-reviewed journal, using PRISMA (Preferred Reporting Items for Systematic reviews and Meta-analysis) guidelines.

TRIAL REGISTRATION NUMBER: The systematic review protocol is registered on PROSPERO (International Prospective Register of Systematic Reviews): CRD42015017525.

PMID: 26560061 [PubMed - in process]

[Etiologies and clinical features of 19 cases with bilateral acute sensorineural hearing loss].

[Etiologies and clinical features of 19 cases with bilateral acute sensorineural hearing loss].:

Related Articles
[Etiologies and clinical features of 19 cases with bilateral acute sensorineural hearing loss].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Jan;50(1):3-7

Authors: Gao X, Liu L, Huang Y, Lu H, Ouyang J, Wang Y

Abstract

OBJECTIVE: To investigate the etiologies and clinical features for bilateral acute sensorineural hearing loss (bi-ASNHL).

METHODS: The clinical data of 19 cases presenting with bi-ASNHL were retrospectively analyzed, including the clinical features, systemic examinations, laboratory examinations, audiology and radiology results, as well as the prognosis.

RESULTS: There were 15 non-otologic diseases in 19 patients, accounting for 78.9% of the total cases, most of which were disorders with multisystem and multi-organ disorder. The central nervous system diseases including fungal meningitis, tuberculous meningitis, and viral encephalitis in 3 patients. The clinical features of deafness were bilateral, progressive, accompanied with fever, headache, dizziness, nausea, vomiting and change of mental status. There was a decrease in speech recognition score (SRS), and speech recognition threshold (SRT) was obviously inferior to pure tone average (PTA) disproportionally. Diseases of immune system including antineural cytoplasmic antibody (ANCA)-associated systemic vasculitis (AASV), relapsing polychondritis (RP), rheumatoid arthritis (RA), and systemic lupus erythematosus (SLE) in 5 patients. They showed the characteristics of bilateral, progressive and simultaneous autoimmune disease. Hematological and endocrine system diseases including diabetes mellitus, leukemia, and thyroid hypofunction in 5 patients. The deafness had the characteristics of symmetry and progressivity. Otologic diseases including large vestibular aqueduct syndrome (LVAS) and sudden sensorineural hearing loss (SSNHL) in 4 patients; Drug-induced sensorineural deafness happened in 2 patients. After the treatment aimed at the causes, 1 case was cured, 3 patients were markedly effective, 7 patients were effective, and 8 patients were ineffective(including dead and refusal cases), with a total effective rate of 57.9%.

CONCLUSIONS: The most of bi-ASNHL cases are often associated with systemic diseases. Clinicians should analyze the history and clinical characteristics in detail, and complete specific laboratory examinations, audiology and imaging examinations in order to reveal the causative diseases. It should be treated aimed at the etiology.

PMID: 25764919 [PubMed - indexed for MEDLINE]

Retrospective Analysis of Decreasing the Use of Anesthesia in Pediatric Audiology: A Preliminary Study

Retrospective Analysis of Decreasing the Use of Anesthesia in Pediatric Audiology: A Preliminary Study:

Purpose
The purpose of this article is to analyze outcomes of processes aimed at reducing the need for use of anesthesia in evaluating pediatric hearing loss.

Method
A retrospective chart review was completed to assess how often a pediatric hearing evaluation was successful/not successful and auditory brainstem response (ABR) testing with anesthesia was avoided/required following review of orders for ABR testing with anesthesia.

Results
A total of 30% of the patients referred for ABR with anesthesia successfully completed a pediatric hearing evaluation, therefore avoiding anesthesia. Male subjects and subjects with developmental delay were less likely to avoid testing with anesthesia. None of the subjects with a comorbidity of developmental delay completed a pediatric hearing evaluation successfully. Other comorbidities with low success rates were autism spectrum disorder and speech delay. No significant outcome differences were measured as a function of referral source.

Conclusions
Processes implemented in this study resulted in elimination of the need to use anesthesia to evaluate hearing in a large portion of patients referred. Success rates for avoiding anesthesia may vary depending on available resources, physician education, and population tested. Additional benefits of the described process include reduced stress on the health care system and families receiving services.


Spanish for the Audiologist: Is There an App for That?

Spanish for the Audiologist: Is There an App for That?: According to the U.S. Census Bureau, the number of people, 5 years of age and older speaking a language other than English at home has more than doubled within the last three decades. Spanish speakers are prominent in these numbers. Additionally, 41% report speaking English less than “very well.” We can surmise from this data that a significant number of patients/families seeking hearing health services from audiologists may have limited English proficiency or a language barrier. In contrast, according to ASHA demographics, the majority of audiologists in the United States are monolingual and speak primarily English. Audiology, a discipline with communication at its heart, is in a distinctive position to continue to provide high-quality, accessible, culturally sensitive services, regardless of language barriers. Ten audiologists in northern NJ volunteered to try a real time translation mobile app (Google Translate App) and document their experiences with the use of this tool with their Spanish-speaking patients/families. Results suggest that a mobile translation app may be a viable option to address language barriers in the audiology practice when professional and/or ad-hoc interpreters are not available. Technology driven solutions can then be applied to customize the translation apps to the specific needs of the audiology practice (e.g., vernacular used in adult vs. pediatric populations, or vestibular vs. rehabilitation terminology). Healthcare literacy is also addressed in the content of patient education and cultural competence.


A warning to the Brazilian Speech-Language Pathology and Audiology community about the importance of scientific and clinical activities in primary progressive aphasia

A warning to the Brazilian Speech-Language Pathology and Audiology community about the importance of scientific and clinical activities in primary progressive aphasia: RESUMO Este artigo tem como objetivo alertar a comunidade científica fonoaudiológica brasileira sobre a importância e necessidade da atuação científica e clínica a respeito da Afasia Progressiva Primária. Esse alerta é fundamentado em um levantamento bibliográfico sistemático da produção científica brasileira sobre Afasia Progressiva Primária, a partir do qual foram encontrados nove artigos brasileiros. Percebe-se que há uma evidente escassez de estudos sobre o tema, pois todos os artigos encontrados foram publicados em periódicos da área médica e boa parte deles foi composta por amostras pequenas, sendo que dois descreveram a efetividade da reabilitação fonoaudiológica de pacientes com Afasia Progressiva Primária. São discutidas perspectivas futuras na área, bem como características da terapia fonoaudiológica para Afasia Progressiva Primária. Concluiu-se que é evidente a necessidade de uma maior atuação da fonoaudiologia nas Afasias Progressivas Primárias.


ABSTRACT This article aims to warn the Brazilian Speech-Language Pathology and Audiology scientific community about the importance and necessity of scientific and clinical activities regarding Primary Progressive Aphasia. This warning is based on a systematic literature review of the scientific production on Primary Progressive Aphasia, from which nine Brazilian articles were selected. It was observed that there is an obvious lack of studies on the subject, as all the retrieved articles were published in medical journals and much of it consisted of small samples; only two articles described the effectiveness of speech-language therapy in patients with Primary Progressive Aphasia. A perspective for the future in the area and characteristics of Speech-Language Therapy for Primary Progressive Aphasia are discussed. As a conclusion, it is evident the need for greater action by Speech-Language Pathology and Audiology on Primary Progressive Aphasia.


Speech language therapy bilingual clinic, a written language therapeutical proposal to deaf people: case report

Speech language therapy bilingual clinic, a written language therapeutical proposal to deaf people: case report: RESUMO Objetivo: O objetivo deste estudo foi analisar produções escritas de um sujeito surdo em processo de apropriação da escrita. Métodos: Participou dessa pesquisa um sujeito surdo, reconhecido pela inicial R., em conjunto com a sua fonoaudióloga. Cabe esclarecer que tal profissional, proficiente em língua de sinais, atuou como interlocutora e intérprete, priorizando a natureza interativa da linguagem e interferindo nas produções escritas apenas quando solicitada. Resultados: Durante os três anos trabalhados com R., observou-se uma mudança de postura perante a língua escrita. Além disso, ele passou a refletir sobre seus textos e a utilizar a Língua Portuguesa de maneira que seus textos tornaram-se mais coerentes para os leitores. A escrita tornou-se, assim, um espaço a mais de manifestação da singularidade de R., que passou a reconstruir sua história de relação com a linguagem. Conclusão: O trabalho fonoaudiológico em uma clínica bilíngue, por meio do qual os surdos podem ter acesso precoce à língua de sinais, pode possibilitar o desenvolvimento da modalidade escrita da Língua Portuguesa.


ABSTRACT Purpose: This study aimed to analyze the written production of a deaf person who is in the process of written language acquisition. Methods: One person with hearing disability, called R., participated in this study together with his Speech Language Pathologist. The therapist, proficient in sign language, acted as an interlocutor and interpreter, prioritizing the interactive nature of language and interfering in the written production only when it was requested. Results: During the 3 years of work with R., a change in stance toward written language was observed. In addition, he began to reflect on his texts and utilize written Portuguese in a way that allowed his texts to be more coherent. Writing became an opportunity to show his singularity and to begin reconstructing his relationship with language. Conclusion: Speech language pathology and audiology therapy, at a bilingual clinic, can allow people with hearing disability early access to sign language and, consequently, enable the development of the written form of Portuguese.


Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speed

Knowledge about simultaneous contributions of tissuemicrostructure and elastic properties on ultrasound speed in cortical bone is limited. In a previous study, porosities and elastic coefficients of cortical bone in human femurs were shown to change with age. In the present study, influences of inter-individual and site-dependent variation in cortical bone microstructure and elastic properties on radial speed of sound(SOS; at 4, 6, and 8 MHz) were investigated using three-dimensional (3D) finite difference time domain modeling. Models with fixed (nominal model) and sample-specific (sample-specific model) values of radial elastic coefficients were compared. Elastic coefficients and microstructure for samples (n = 24) of human femoral shafts (n = 6) were derived using scanning acoustic microscopy and micro-computed tomography images, respectively. Porosity-related SOS varied more extensively in nominal models than in sample-specific models. Linear correlation between pore separation and SOS was similar (R = 0.8, p R2 = 0.75, p SOS, especially at 4 MHz, was highest in the posterior quadrant. The determination coefficient was lower for models with sample-specific values of radial elastic coefficient implemented (R2 p R2p in vivo pulse-echo cortical thickness measurements applying constant SOS.



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Level dependence of the nonlinear-distortion component of distortion-product otoacoustic emissions in humansa)

Distortion-product otoacoustic emissions (DPOAEs) emerge when presenting two primary tones with different frequencies f1 and f2 to the cochlea and are commonly used in diagnosis and research to evaluate the functional state of the cochlea. Optimal primary-tone stimulus levels accounting for the different level dependencies of the traveling-wave amplitudes of the two primary tones near the f2-tonotopic place on the basilar membrane are often used to maximize DPOAE amplitudes. However, parameters defining the optimal levels can be affected by wave interference between the nonlinear-distortion and coherent-reflection components of the DPOAE. Here, the components were separated in the time domain using a pulsed stimulus paradigm and optimal levels determined. Based on the amplitude dependence of the nonlinear-distortion components on primary-tone stimulus levels, level parameters yielding maximum DPOAE amplitudes were derived for six normal-hearing adults and compared to data recorded with continuous two-tone stimulation. The level parameters resulting from analysis of the nonlinear-distortion components show dependence on stimulus frequency and small standard deviations. DPOAE input/output functions derived for optimal levels exhibit larger slopes, wider dynamic range and less variability across subjects than those derived for conventional stimulus and analysis conditions, potentially increasing their reliability and sensitivity for assessing cochlea function.



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Experimental validation of a topology optimized acoustic cavity

This paper presents the experimental validation of an acoustic cavity designed using topology optimization with the goal of minimizing the sound pressure locally for monochromatic excitation. The presented results show good agreement between simulations and measurements. The effect of damping, errors in the production of the cavity, and variations in operating frequency is discussed and the importance of taking these factors into account in the modeling process is highlighted.



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Ocean acoustic reverberation tomography

Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., acoustic wave field densely samples properties of the water column over the width of the receiver array. A method, referred to as ocean acoustic reverberation tomography, is developed that uses the travel times of direct and reflected waves to image ocean acousticstructure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography.



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Contents List

Publication date: January 2016
Source:Gait & Posture, Volume 43





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Editorial Board

Publication date: January 2016
Source:Gait & Posture, Volume 43





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Reproducibility of kinematic measures of the thoracic spine, lumbar spine and pelvis during fast running

Publication date: January 2016
Source:Gait & Posture, Volume 43
Author(s): D.L. Mason, S.J. Preece, C.A. Bramah, L.C. Herrington
This study evaluated the reproducibility of the angular rotations of the thoracic spine, lumbar spine, pelvis and lower extremity during running. In addition, the study compared kinematic reproducibility between two methods for calculating kinematic trajectories: a six degrees of freedom (6DOF) approach and a global optimisation (GO) approach. With the first approach segments were treated independently, however with GO approach joint constraints were imposed to stop translation of adjacent segments. A total of 12 athletes were tested on two separate days whilst running over ground at a speed of 5.6ms−1. The results demonstrated good between-day reproducibility for most kinematic parameters in the frontal and transverse planes with typical angular errors of 1.4–3°. Acceptable repeatability was also found in the sagittal plane. However, in this plane, although kinematic waveform shape was preserved between testing session, there were sometimes shifts in curve offset which lead to slightly higher angular errors, typically ranging from 1.9° to 3.5°. In general, the results demonstrated similar levels of reproducibility for both computational approaches (6DOF and, GO) and therefore suggest that GO may not lead to improved kinematic reproducibility during running.



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Contents List

Publication date: January 2016
Source:Gait & Posture, Volume 43





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Publication date: January 2016
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Reproducibility of kinematic measures of the thoracic spine, lumbar spine and pelvis during fast running

Publication date: January 2016
Source:Gait & Posture, Volume 43
Author(s): D.L. Mason, S.J. Preece, C.A. Bramah, L.C. Herrington
This study evaluated the reproducibility of the angular rotations of the thoracic spine, lumbar spine, pelvis and lower extremity during running. In addition, the study compared kinematic reproducibility between two methods for calculating kinematic trajectories: a six degrees of freedom (6DOF) approach and a global optimisation (GO) approach. With the first approach segments were treated independently, however with GO approach joint constraints were imposed to stop translation of adjacent segments. A total of 12 athletes were tested on two separate days whilst running over ground at a speed of 5.6ms−1. The results demonstrated good between-day reproducibility for most kinematic parameters in the frontal and transverse planes with typical angular errors of 1.4–3°. Acceptable repeatability was also found in the sagittal plane. However, in this plane, although kinematic waveform shape was preserved between testing session, there were sometimes shifts in curve offset which lead to slightly higher angular errors, typically ranging from 1.9° to 3.5°. In general, the results demonstrated similar levels of reproducibility for both computational approaches (6DOF and, GO) and therefore suggest that GO may not lead to improved kinematic reproducibility during running.



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Contents List

Publication date: January 2016
Source:Gait & Posture, Volume 43





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Publication date: January 2016
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Reproducibility of kinematic measures of the thoracic spine, lumbar spine and pelvis during fast running

Publication date: January 2016
Source:Gait & Posture, Volume 43
Author(s): D.L. Mason, S.J. Preece, C.A. Bramah, L.C. Herrington
This study evaluated the reproducibility of the angular rotations of the thoracic spine, lumbar spine, pelvis and lower extremity during running. In addition, the study compared kinematic reproducibility between two methods for calculating kinematic trajectories: a six degrees of freedom (6DOF) approach and a global optimisation (GO) approach. With the first approach segments were treated independently, however with GO approach joint constraints were imposed to stop translation of adjacent segments. A total of 12 athletes were tested on two separate days whilst running over ground at a speed of 5.6ms−1. The results demonstrated good between-day reproducibility for most kinematic parameters in the frontal and transverse planes with typical angular errors of 1.4–3°. Acceptable repeatability was also found in the sagittal plane. However, in this plane, although kinematic waveform shape was preserved between testing session, there were sometimes shifts in curve offset which lead to slightly higher angular errors, typically ranging from 1.9° to 3.5°. In general, the results demonstrated similar levels of reproducibility for both computational approaches (6DOF and, GO) and therefore suggest that GO may not lead to improved kinematic reproducibility during running.



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Inter-individual changes in cortical bone three-dimensional microstructure and elastic coefficient have opposite effects on radial sound speed

Knowledge about simultaneous contributions of tissuemicrostructure and elastic properties on ultrasound speed in cortical bone is limited. In a previous study, porosities and elastic coefficients of cortical bone in human femurs were shown to change with age. In the present study, influences of inter-individual and site-dependent variation in cortical bone microstructure and elastic properties on radial speed of sound(SOS; at 4, 6, and 8 MHz) were investigated using three-dimensional (3D) finite difference time domain modeling. Models with fixed (nominal model) and sample-specific (sample-specific model) values of radial elastic coefficients were compared. Elastic coefficients and microstructure for samples (n = 24) of human femoral shafts (n = 6) were derived using scanning acoustic microscopy and micro-computed tomography images, respectively. Porosity-related SOS varied more extensively in nominal models than in sample-specific models. Linear correlation between pore separation and SOS was similar (R = 0.8, p R2 = 0.75, p SOS, especially at 4 MHz, was highest in the posterior quadrant. The determination coefficient was lower for models with sample-specific values of radial elastic coefficient implemented (R2 p R2p in vivo pulse-echo cortical thickness measurements applying constant SOS.



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Level dependence of the nonlinear-distortion component of distortion-product otoacoustic emissions in humansa)

Distortion-product otoacoustic emissions (DPOAEs) emerge when presenting two primary tones with different frequencies f1 and f2 to the cochlea and are commonly used in diagnosis and research to evaluate the functional state of the cochlea. Optimal primary-tone stimulus levels accounting for the different level dependencies of the traveling-wave amplitudes of the two primary tones near the f2-tonotopic place on the basilar membrane are often used to maximize DPOAE amplitudes. However, parameters defining the optimal levels can be affected by wave interference between the nonlinear-distortion and coherent-reflection components of the DPOAE. Here, the components were separated in the time domain using a pulsed stimulus paradigm and optimal levels determined. Based on the amplitude dependence of the nonlinear-distortion components on primary-tone stimulus levels, level parameters yielding maximum DPOAE amplitudes were derived for six normal-hearing adults and compared to data recorded with continuous two-tone stimulation. The level parameters resulting from analysis of the nonlinear-distortion components show dependence on stimulus frequency and small standard deviations. DPOAE input/output functions derived for optimal levels exhibit larger slopes, wider dynamic range and less variability across subjects than those derived for conventional stimulus and analysis conditions, potentially increasing their reliability and sensitivity for assessing cochlea function.



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Experimental validation of a topology optimized acoustic cavity

This paper presents the experimental validation of an acoustic cavity designed using topology optimization with the goal of minimizing the sound pressure locally for monochromatic excitation. The presented results show good agreement between simulations and measurements. The effect of damping, errors in the production of the cavity, and variations in operating frequency is discussed and the importance of taking these factors into account in the modeling process is highlighted.



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Ocean acoustic reverberation tomography

Seismic wide-angle imaging using ship-towed acoustic sources and networks of ocean bottom seismographs is a common technique for exploring earth structure beneath the oceans. In these studies, the recorded data are dominated by acoustic waves propagating as reverberations in the water column. For surveys with a small receiver spacing (e.g., acoustic wave field densely samples properties of the water column over the width of the receiver array. A method, referred to as ocean acoustic reverberation tomography, is developed that uses the travel times of direct and reflected waves to image ocean acousticstructure. Reverberation tomography offers an alternative approach for determining the structure of the oceans and advancing the understanding of ocean heat content and mixing processes. The technique has the potential for revealing small-scale ocean thermal structure over the entire vertical height of the water column and along long survey profiles or across three-dimensional volumes of the ocean. For realistic experimental geometries and data noise levels, the method can produce images of ocean sound speed on a smaller scale than traditional acoustic tomography.



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Stress “Deafness” Reveals Absence of Lexical Marking of Stress or Tone in the Adult Grammar

by Hamed Rahmani, Toni Rietveld, Carlos Gussenhoven

A Sequence Recall Task with disyllabic stimuli contrasting either for the location of prosodic prominence or for the medial consonant was administered to 150 subjects equally divided over five language groups. Scores showed a significant interaction between type of contrast and language group, such that groups did not differ on their performance on the consonant contrast, while two language groups, Dutch and Japanese, significantly outperformed the three other language groups (French, Indonesian and Persian) on the prosodic contrast. Since only Dutch and Japanese words have unpredictable stress or accent locations, the results are interpreted to mean that stress “deafness” is a property of speakers of languages without lexical stress or tone markings, as opposed to the presence of stress or accent contrasts in phrasal (post-lexical) constructions. Moreover, the degree of transparency between the locations of stress/tone and word boundaries did not appear to affect our results, despite earlier claims that this should have an effect. This finding is of significance for speech processing, language acquisition and phonological theory.

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