Τρίτη 10 Οκτωβρίου 2017

A Subjective Rating Scale for Initial Assessment of Sudden Unilateral Sensorineural Hearing Loss

Objective: To examine the value of a subjective numerical rating scale (NRS) in the initial evaluation of patients suspected of suffering from unilateral sudden sensorineural hearing loss (SSNHL) until a formal audiogram is available. Study Design: Prospective noncontrolled clinical study. Methods: Thirty-one consecutive patients referred to the emergency department due to suspected unilateral SSNHL and with no other aural pathology by history or physical examination were enrolled. Patients were asked to characterize the severity of their hearing loss using an NRS of 1 (normal hearing) to 6 (complete deafness). SSNHL was defined as an SNHL of at least 30 dB over 3 consecutive frequencies that occurred in 3 days or less. A formal audiogram was obtained subsequently as soon as available. Results: Twenty-four patients were treated with steroids and met the audiometric criteria of SSNHL. All scored their NRS as 3 or more. None of the 7 patients whose NRS grades were ≤2.5 met the criteria for SSNHL. Two patients were treated with steroids although their hearing did not meet the audiometric criteria for SSNHL as the hearing loss was limited to 2 consecutive frequencies. The NRS score for both was Conclusion: In addition to the patient's history and physical examination, a NRS can be a useful tool in the preliminary assessment of patients suspected of having SSNHL until audiometry becomes available. In the scale of 1-6, an NRS score of 3 or more reliably predicts the need to treat the patient with steroids according to the accepted criteria.
Audiol Neurotol 2017;22:154-159

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Analysis of spastic gait in cervical myelopathy: linking compression ratio to spatiotemporal and pedobarographic parameters

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Publication date: Available online 10 October 2017
Source:Gait & Posture
Author(s): Taro Nagai, Yasuhito Takahashi, Kenji Endo, Ryo Ikegami, Ryuichi Ueno, Kengo Yamamoto
BackgroundGait dysfunction associated with spasticity and hyperreflexia is a primary symptom in patients with compression of cervical spinal cord. The objective of this study was to link maximum compression ratio (CR) to spatiotemporal/pedobarographic parameters.MethodsQuantitative gait analysis was performed by using a pedobarograph in 75 elderly males with a wide range of cervical compression severity. CR values were characterized on T1-weighted magnetic resonance imaging (MRI). Statistical significances in gait analysis parameters (speed, cadence, stride length, step with, and toe-out angle) were evaluated among different CR groups by the non-parametric Kruskal-Wallis test followed by the Mann-Whitney U test using Bonferroni correction. The Spearman test was performed to verify correlations between CR and gait parameters.ResultsThe Kruskal-Wallis test revealed significant decline in gait speed and stride length and significant increase in toe-out angle with progression of cervical compression myelopathy. The post-hoc Mann-Whitney U test showed significant differences in these parameters between the control group (0.45<CR) and the worst myelopathy group (CR≤0.25). Cadence and step width did not significantly change with CR. On the other hand, the Spearman test revealed that CR was significantly correlated with speed, cadence, stride length, and toe-out angle.ConclusionGait speed, stride length, and toe-out angle can serve as useful indexes for evaluating progressive gait abnormality in cervical myelopathy. Our findings suggest that CR≤0.25 is associated with significantly poorer gait performance. Nevertheless, future prospective studies are needed to determine a potential benefit from decompressive surgery in such severe compression patients.



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The Bit Doesn’t Fit: Evaluation of a Commercial Activity-Tracker at Slower Walking Speeds

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Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Christopher K. Wong, Helena M. Mentis, Ravi Kuber
Accelerometer-based commercial activity trackers are a low-cost and convenient method for monitoring and assessing health measures such as gait. However, the accuracy of these activity trackers in slow walking conditions on a minute-by-minute basis is largely unknown. In this study, the accuracy of a hip-worn commercial activity tracker (FitBit Ultra) was examined through step counts. Accuracy was evaluated through four minute trials of treadmill walking at speeds representative of older adults (0.9, 1.1, and 1.3m/s). Minute-by-minute step count was extracted through the FitBit API and compared it to observer counted steps through video recordings. Results highlighted a significant over-reporting of steps at the highest speed, and a significant under-reporting of steps at the slowest speed, with the FitBit Ultra failing to count steps for one or more minutes at the slowest speed for 11 participants. This study highlights problems with using the FitBit Ultra by slow-walking populations, and recommends that researchers and clinicians should carefully consider the trade-off between accuracy and convenience when using commercial activity trackers with slow-walking populations.



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Classification and analysis of the natural corner curving motion of humans based on gait motion

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Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Yasuhiro Akiyama, Hitoshi Toda, Takao Ogura, Shogo Okamoto, Yoji Yamada
The curving motion of the human body is more complex than gait motion for straight walking. In particular, when human can freely curve corners, the gait motion varies among and even within individuals. However, is it not possible to classify natural curving motion using a statistical method? This study investigates the natural curving motion, encompassing various walking paths selected by subjects, as opposed to previous studies that focused on specific stepping strategies or curving motion under precisely controlled conditions. As a result, the natural curving motions are statistically classified into five distinct groups based on certain motion indices. Each group represents a curving strategy and is mainly characterized by the inner inclination of the pelvis, outer rotation of hip joints at the time of heel contact of the inner leg, and inner and/or outer rotation of hip joints at the time of heel contact of the outer leg. Such strategies are speculated as typical motions within the large variation in natural curving motion. Another finding is that, unlike the joint pattern of lower limb joints in the sagittal plane, hip rotation and the abduction/adduction angle drastically change when curving. In particular, the large inner rotation and abduction angles of the hip joint of both legs, which reached approximately 30 and 10, respectively, become important when considering the curving gait of a physical assistant robot. Our analysis and findings help specify the joint motion required for physical assistant robots.



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Analysis of spastic gait in cervical myelopathy: linking compression ratio to spatiotemporal and pedobarographic parameters

S09666362.gif

Publication date: Available online 10 October 2017
Source:Gait & Posture
Author(s): Taro Nagai, Yasuhito Takahashi, Kenji Endo, Ryo Ikegami, Ryuichi Ueno, Kengo Yamamoto
BackgroundGait dysfunction associated with spasticity and hyperreflexia is a primary symptom in patients with compression of cervical spinal cord. The objective of this study was to link maximum compression ratio (CR) to spatiotemporal/pedobarographic parameters.MethodsQuantitative gait analysis was performed by using a pedobarograph in 75 elderly males with a wide range of cervical compression severity. CR values were characterized on T1-weighted magnetic resonance imaging (MRI). Statistical significances in gait analysis parameters (speed, cadence, stride length, step with, and toe-out angle) were evaluated among different CR groups by the non-parametric Kruskal-Wallis test followed by the Mann-Whitney U test using Bonferroni correction. The Spearman test was performed to verify correlations between CR and gait parameters.ResultsThe Kruskal-Wallis test revealed significant decline in gait speed and stride length and significant increase in toe-out angle with progression of cervical compression myelopathy. The post-hoc Mann-Whitney U test showed significant differences in these parameters between the control group (0.45<CR) and the worst myelopathy group (CR≤0.25). Cadence and step width did not significantly change with CR. On the other hand, the Spearman test revealed that CR was significantly correlated with speed, cadence, stride length, and toe-out angle.ConclusionGait speed, stride length, and toe-out angle can serve as useful indexes for evaluating progressive gait abnormality in cervical myelopathy. Our findings suggest that CR≤0.25 is associated with significantly poorer gait performance. Nevertheless, future prospective studies are needed to determine a potential benefit from decompressive surgery in such severe compression patients.



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The Bit Doesn’t Fit: Evaluation of a Commercial Activity-Tracker at Slower Walking Speeds

S09666362.gif

Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Christopher K. Wong, Helena M. Mentis, Ravi Kuber
Accelerometer-based commercial activity trackers are a low-cost and convenient method for monitoring and assessing health measures such as gait. However, the accuracy of these activity trackers in slow walking conditions on a minute-by-minute basis is largely unknown. In this study, the accuracy of a hip-worn commercial activity tracker (FitBit Ultra) was examined through step counts. Accuracy was evaluated through four minute trials of treadmill walking at speeds representative of older adults (0.9, 1.1, and 1.3m/s). Minute-by-minute step count was extracted through the FitBit API and compared it to observer counted steps through video recordings. Results highlighted a significant over-reporting of steps at the highest speed, and a significant under-reporting of steps at the slowest speed, with the FitBit Ultra failing to count steps for one or more minutes at the slowest speed for 11 participants. This study highlights problems with using the FitBit Ultra by slow-walking populations, and recommends that researchers and clinicians should carefully consider the trade-off between accuracy and convenience when using commercial activity trackers with slow-walking populations.



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Classification and analysis of the natural corner curving motion of humans based on gait motion

S09666362.gif

Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Yasuhiro Akiyama, Hitoshi Toda, Takao Ogura, Shogo Okamoto, Yoji Yamada
The curving motion of the human body is more complex than gait motion for straight walking. In particular, when human can freely curve corners, the gait motion varies among and even within individuals. However, is it not possible to classify natural curving motion using a statistical method? This study investigates the natural curving motion, encompassing various walking paths selected by subjects, as opposed to previous studies that focused on specific stepping strategies or curving motion under precisely controlled conditions. As a result, the natural curving motions are statistically classified into five distinct groups based on certain motion indices. Each group represents a curving strategy and is mainly characterized by the inner inclination of the pelvis, outer rotation of hip joints at the time of heel contact of the inner leg, and inner and/or outer rotation of hip joints at the time of heel contact of the outer leg. Such strategies are speculated as typical motions within the large variation in natural curving motion. Another finding is that, unlike the joint pattern of lower limb joints in the sagittal plane, hip rotation and the abduction/adduction angle drastically change when curving. In particular, the large inner rotation and abduction angles of the hip joint of both legs, which reached approximately 30 and 10, respectively, become important when considering the curving gait of a physical assistant robot. Our analysis and findings help specify the joint motion required for physical assistant robots.



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Analysis of spastic gait in cervical myelopathy: linking compression ratio to spatiotemporal and pedobarographic parameters

S09666362.gif

Publication date: Available online 10 October 2017
Source:Gait & Posture
Author(s): Taro Nagai, Yasuhito Takahashi, Kenji Endo, Ryo Ikegami, Ryuichi Ueno, Kengo Yamamoto
BackgroundGait dysfunction associated with spasticity and hyperreflexia is a primary symptom in patients with compression of cervical spinal cord. The objective of this study was to link maximum compression ratio (CR) to spatiotemporal/pedobarographic parameters.MethodsQuantitative gait analysis was performed by using a pedobarograph in 75 elderly males with a wide range of cervical compression severity. CR values were characterized on T1-weighted magnetic resonance imaging (MRI). Statistical significances in gait analysis parameters (speed, cadence, stride length, step with, and toe-out angle) were evaluated among different CR groups by the non-parametric Kruskal-Wallis test followed by the Mann-Whitney U test using Bonferroni correction. The Spearman test was performed to verify correlations between CR and gait parameters.ResultsThe Kruskal-Wallis test revealed significant decline in gait speed and stride length and significant increase in toe-out angle with progression of cervical compression myelopathy. The post-hoc Mann-Whitney U test showed significant differences in these parameters between the control group (0.45<CR) and the worst myelopathy group (CR≤0.25). Cadence and step width did not significantly change with CR. On the other hand, the Spearman test revealed that CR was significantly correlated with speed, cadence, stride length, and toe-out angle.ConclusionGait speed, stride length, and toe-out angle can serve as useful indexes for evaluating progressive gait abnormality in cervical myelopathy. Our findings suggest that CR≤0.25 is associated with significantly poorer gait performance. Nevertheless, future prospective studies are needed to determine a potential benefit from decompressive surgery in such severe compression patients.



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The Bit Doesn’t Fit: Evaluation of a Commercial Activity-Tracker at Slower Walking Speeds

S09666362.gif

Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Christopher K. Wong, Helena M. Mentis, Ravi Kuber
Accelerometer-based commercial activity trackers are a low-cost and convenient method for monitoring and assessing health measures such as gait. However, the accuracy of these activity trackers in slow walking conditions on a minute-by-minute basis is largely unknown. In this study, the accuracy of a hip-worn commercial activity tracker (FitBit Ultra) was examined through step counts. Accuracy was evaluated through four minute trials of treadmill walking at speeds representative of older adults (0.9, 1.1, and 1.3m/s). Minute-by-minute step count was extracted through the FitBit API and compared it to observer counted steps through video recordings. Results highlighted a significant over-reporting of steps at the highest speed, and a significant under-reporting of steps at the slowest speed, with the FitBit Ultra failing to count steps for one or more minutes at the slowest speed for 11 participants. This study highlights problems with using the FitBit Ultra by slow-walking populations, and recommends that researchers and clinicians should carefully consider the trade-off between accuracy and convenience when using commercial activity trackers with slow-walking populations.



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Classification and analysis of the natural corner curving motion of humans based on gait motion

S09666362.gif

Publication date: Available online 9 October 2017
Source:Gait & Posture
Author(s): Yasuhiro Akiyama, Hitoshi Toda, Takao Ogura, Shogo Okamoto, Yoji Yamada
The curving motion of the human body is more complex than gait motion for straight walking. In particular, when human can freely curve corners, the gait motion varies among and even within individuals. However, is it not possible to classify natural curving motion using a statistical method? This study investigates the natural curving motion, encompassing various walking paths selected by subjects, as opposed to previous studies that focused on specific stepping strategies or curving motion under precisely controlled conditions. As a result, the natural curving motions are statistically classified into five distinct groups based on certain motion indices. Each group represents a curving strategy and is mainly characterized by the inner inclination of the pelvis, outer rotation of hip joints at the time of heel contact of the inner leg, and inner and/or outer rotation of hip joints at the time of heel contact of the outer leg. Such strategies are speculated as typical motions within the large variation in natural curving motion. Another finding is that, unlike the joint pattern of lower limb joints in the sagittal plane, hip rotation and the abduction/adduction angle drastically change when curving. In particular, the large inner rotation and abduction angles of the hip joint of both legs, which reached approximately 30 and 10, respectively, become important when considering the curving gait of a physical assistant robot. Our analysis and findings help specify the joint motion required for physical assistant robots.



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An operating principle of the turtle utricle to detect wide dynamic range

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Publication date: Available online 9 October 2017
Source:Hearing Research
Author(s): Jong-Hoon Nam
The utricle encodes both static information such as head orientation, and dynamic information such as vibrations. It is not well understood how the utricle can encode both static and dynamic information for a wide dynamic range (from <0.05 to >2 times the gravitational acceleration; from DC to > 1000 Hz vibrations). Using computational models of the hair cells in the turtle utricle, this study presents an explanation on how the turtle utricle encodes stimulations over such a wide dynamic range. Two hair bundles were modeled using the finite element method—one representing the striolar hair cell (Cell S), and the other representing the medial extrastriolar hair cell (Cell E). A mechano-transduction (MET) channel model was incorporated to compute MET current (iMET) due to hair bundle deflection. A macro-mechanical model of the utricle was used to compute otoconial motions from head accelerations (aHead). According to known anatomical data, Cell E has a long kinocilium that is embedded into the stiff otoconial layer. Unlike Cell E, the hair bundle of Cell S falls short of the otoconial layer. Considering such difference in the mechanical connectivity between the hair cell bundle and the otoconial layer, three cases were simulated: Cell E displacement-clamped, Cell S viscously-coupled, and Cell S displacement-clamped. Head accelerations at different amplitude levels and different frequencies were simulated for the three cases. When a realistic head motion was simulated, Cell E was responsive to head orientation, while the viscously-coupled Cell S was responsive to fast head motion imitating the feeding strike of a turtle.



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An operating principle of the turtle utricle to detect wide dynamic range

S03785955.gif

Publication date: Available online 9 October 2017
Source:Hearing Research
Author(s): Jong-Hoon Nam
The utricle encodes both static information such as head orientation, and dynamic information such as vibrations. It is not well understood how the utricle can encode both static and dynamic information for a wide dynamic range (from <0.05 to >2 times the gravitational acceleration; from DC to > 1000 Hz vibrations). Using computational models of the hair cells in the turtle utricle, this study presents an explanation on how the turtle utricle encodes stimulations over such a wide dynamic range. Two hair bundles were modeled using the finite element method—one representing the striolar hair cell (Cell S), and the other representing the medial extrastriolar hair cell (Cell E). A mechano-transduction (MET) channel model was incorporated to compute MET current (iMET) due to hair bundle deflection. A macro-mechanical model of the utricle was used to compute otoconial motions from head accelerations (aHead). According to known anatomical data, Cell E has a long kinocilium that is embedded into the stiff otoconial layer. Unlike Cell E, the hair bundle of Cell S falls short of the otoconial layer. Considering such difference in the mechanical connectivity between the hair cell bundle and the otoconial layer, three cases were simulated: Cell E displacement-clamped, Cell S viscously-coupled, and Cell S displacement-clamped. Head accelerations at different amplitude levels and different frequencies were simulated for the three cases. When a realistic head motion was simulated, Cell E was responsive to head orientation, while the viscously-coupled Cell S was responsive to fast head motion imitating the feeding strike of a turtle.



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An operating principle of the turtle utricle to detect wide dynamic range

S03785955.gif

Publication date: Available online 9 October 2017
Source:Hearing Research
Author(s): Jong-Hoon Nam
The utricle encodes both static information such as head orientation, and dynamic information such as vibrations. It is not well understood how the utricle can encode both static and dynamic information for a wide dynamic range (from <0.05 to >2 times the gravitational acceleration; from DC to > 1000 Hz vibrations). Using computational models of the hair cells in the turtle utricle, this study presents an explanation on how the turtle utricle encodes stimulations over such a wide dynamic range. Two hair bundles were modeled using the finite element method—one representing the striolar hair cell (Cell S), and the other representing the medial extrastriolar hair cell (Cell E). A mechano-transduction (MET) channel model was incorporated to compute MET current (iMET) due to hair bundle deflection. A macro-mechanical model of the utricle was used to compute otoconial motions from head accelerations (aHead). According to known anatomical data, Cell E has a long kinocilium that is embedded into the stiff otoconial layer. Unlike Cell E, the hair bundle of Cell S falls short of the otoconial layer. Considering such difference in the mechanical connectivity between the hair cell bundle and the otoconial layer, three cases were simulated: Cell E displacement-clamped, Cell S viscously-coupled, and Cell S displacement-clamped. Head accelerations at different amplitude levels and different frequencies were simulated for the three cases. When a realistic head motion was simulated, Cell E was responsive to head orientation, while the viscously-coupled Cell S was responsive to fast head motion imitating the feeding strike of a turtle.



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