Κυριακή 7 Φεβρουαρίου 2021

Surgical approach to the facial recess influences the acceptable trajectory of cochlear implantation electrodes.

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Surgical approach to the facial recess influences the acceptable trajectory of cochlear implantation electrodes.

Eur Arch Otorhinolaryngol. 2021 Feb 05;:

Authors: Copson B, Wijewickrema S, Ma X, Zhou Y, Gerard JM, O'Leary S

Abstract
PURPOSE: To provide practical guidance to the operative surgeon by mapping the location, where acceptable straight-line virtual cochlear implant electrode trajectories intersect the facial recess. In addition, to investigate the influence of facial recess preparation, virtual electrode width and surgical approach to the cochlea on these available trajectories.
METHODS: The study was performed on imaging data from eight cadaveric temporal bones within the University of Melbourne Virtual Reality (VR) Temporal Bone Surgery Simulator. The facial recess was opened to varying degrees, and acceptable trajectory vectors with varying diameters were calculated for electrode insertions via cochleostomy or round window membrane (RWM). The percentage of acceptable insertion vectors through each location of the facial recess was visually represented using heatmaps.
RESULTS: Seven of the eight bones allowed for acceptable vector trajectories via both cochleostomy and RWM approaches. These acceptable trajectories were more likely to lie superiorly within the facial recess for insertion via the round window, and inferiorly for insertion via cochleostomy. Cochleostomy insertions required a greater degree of preparation and skeletonisation of the junction of the facial nerve and chorda tympani within the facial recess. The width of the virtual electrode had only marginal impact on the availability of acceptable trajectories. Heatmaps emphasised the intimate relationship the acceptable trajectories have with the facial nerve and chorda tympani.
CONCLUSION: These findings highlight the differences in the acceptable straight-line trajectories for electrodes when implanted via the round window or cochleostomy. There were notable exceptions to both surgical approaches, likely explained by the variation of hook region anatomy. The methodology used in this study holds promise for translation to patient specific surgical planning.

PMID: 33547488 [PubMed - as supplied by publisher]

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Benign recurrent vestibulopathy: MRI and vestibular tests results in a series of 128 cases.

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Benign recurrent vestibulopathy: MRI and vestibular tests results in a series of 128 cases.

Eur Arch Otorhinolaryngol. 2021 Feb 06;:

Authors: Ducroz C, Dumas G, Quatre R, Attyé A, Fabre C, Schmerber S

Abstract
PURPOSE: Benign recurrent vestibulopathy is a recent entity, close to probable Meniere's disease and vestibular-migraine. So far, no study has systematically investigated the presence of endolymphatic hydrops of the lateral semicircular canal in benign recurrent vestibulopathy using magnetic resonance imaging. The aim of this study was to determine magnetic resonance imaging data and vestibular test results in patients with benign recurrent vestibulopathy.
METHODS: 128 patients with benign recurrent vestibulopathy included since 2010 were retrospectively analyzed. Patients had magnetic resonance imaging with a delayed acquisition, audiogram, head shaking test, caloric-test, skull-vibration-induced-nystagmus-test, video-head- impulse-test, and vestibular evoked myogenic potential. Endolymphatic hydrops presence was classified into four categories: cochlear, saccular, lateral semicircular canal and association with saccule.
RESULTS: In benign reccurent vestibulopathy, 23% of cases showed an endolymphatic hydrops on magnetic resonance imaging, more frequently located in the lateral semicircular canal (59%) and related to the disease duration. The most often impaired tests were caloric-test (49%) with fluctuations of hypofunction in 67% and skull-vibration-induced-nystagmus-test (61%). No correlation between the caloric-test and the presence and location of the endolymphatic hydrops was observed.
CONCLUSION: In our series of benign reccurent vestibulopathy, a rare endolymphatic hydrops was most often observed for the lateral semicircular canal and correlated with the seniority of the pathology. Hydrops identified at the magnetic resonance imaging was not correlated with the caloric-test results. Skull-vibration-induced-nystagmus-test and caloric-test were the most often modified vestibular tests.

PMID: 33547924 [PubMed - as supplied by publisher]

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The use of periocular fillers in aesthetic medicine.

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The use of periocular fillers in aesthetic medicine.

J Plast Reconstr Aesthet Surg. 2021 Jan 09;:

Authors: Mandal P, Gama F

Abstract
The periocular area is the first to display signs of ageing. Dermal fillers are an increasingly popular, minimally invasive method for facial rejuvenation. The eye is anatomically delicate and complex. Therefore, special consideration must be taken if dermal fillers are employed. This article examines the literature to assess the efficacy and safety of dermal fillers around the eye as well as the management of complications secondary to dermal filler use, such as oedema, granuloma formation, filler migration, xanthelasma, skin necrosis and visual loss. Hyaluronic acid (HA) is the most popular and commonly employed dermal filler for periocular use. It is effective, with good observer improvement and patient satisfaction (p<0.0001). Ninety percent of adverse events are mild in nature and self-resolve within 1 month. Malar oedema is a delayed complication unique to the periocular area, occurring in 11% of patients. This can be managed with use of hyaluronidase if a HA filler has been employed. Other complications, such as granuloma formation, filler migration and xanthelasma, have also been reported with variable management outcomes. Vascular adverse events include skin necrosis and visual loss. No Level 1 evidence exists for the management of visual loss. Two cases of visual restoration have been identified in the literature; however, this is rare.

PMID: 33546985 [PubMed - as supplied by publisher]

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A sling of a normal right inferior vena cava around the abdominal aorta.

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A sling of a normal right inferior vena cava around the abdominal aorta.

Surg Radiol Anat. 2021 Feb 06;:

Authors: Karaosmanoglu AD, Ardali Duzgun S, Akata D, Ozmen MN, Karcaaltincaba M

Abstract
Variations in the anatomy of inferior vena cava (IVC) may have important clinical implications. In-depth knowledge of its embryology and variations are of fundamental importance to prevent any potential medical complications related to anatomic variations of the IVC. In this article, we described a previously unreported, to the best of our knowledge, a variation of IVC. In the case we presented, the IVC was seen almost completely encircling the abdominal aorta. We decided to call this anatomic variation as "a sling of a normal right IVC around the abdominal aorta". Cross-sectional imaging is a prompt and highly reliable method to evaluate IVC anatomy and may have significant clinical importance to prevent any potential complications related to IVC during surgery or interventional radiology procedures.

PMID: 33547916 [PubMed - as supplied by publisher]

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[New approval: Atezolizumab and bevacizumab for first line of unresecable hepatocellular carcinoma].

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[New approval: Atezolizumab and bevacizumab for first line of unresecable hepatocellular carcinoma].

Bull Cancer. 2021 Feb 02;:

Authors: Minot-This MS, Edeline J

PMID: 33546873 [PubMed - as supplied by publisher]

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[Drug approval: Olaparib - metastatic castration-resistant prostate cancer with BRCA mutation].

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[Drug approval: Olaparib - metastatic castration-resistant prostate cancer with BRCA mutation].

Bull Cancer. 2021 Feb 02;:

Authors: Saillant A, Flippot R

PMID: 33546874 [PubMed - as supplied by publisher]

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Radioactive iodine-125 seed localization as an aid in reoperative neck surgery.

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Radioactive iodine-125 seed localization as an aid in reoperative neck surgery.

Am J Surg. 2021 Jan 11;:

Authors: Bortz MD, Khokar A, Winchester DJ, Moo-Young TA, Ecanow DB, Ecanow JS, Prinz RA

Abstract
BACKGROUND: Scarring and disrupted tissue planes add to already-complex neck anatomy and make localization of nonpalpable pathology difficult in cervical endocrine reoperations. We describe the use of radioactive iodine-125 seed localization (RSL) in 6 patients with metastatic papillary thyroid carcinoma (PTC) and 2 with recurrent hyperparathyroidism.
METHODS: Eight patients had 2-D ultrasound-guided RSL of the target lesion, 0-3 days preoperatively. Intraoperative gamma probe (Neoprobe) was used to plan incision placement and localize the implanted seed. Recorded operative variables included: number of lymph nodes (LNs) harvested, estimated blood loss (EBL), operative time, length of stay (LOS) and RSL and operative complications.
RESULTS: All patients had successful resection of the targeted area and removal of the radioactive seed. There was no seed migration. Two complications occurred in the thyroid group.
CONCLUSION: Radioactive iodine 125 seeds facilitate successful localization of endocrine pathology during reoperative cervical procedures.

PMID: 33546853 [PubMed - as supplied by publisher]

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Zinc-based triazole metal complexes for efficient iodine adsorption in water.

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Zinc-based triazole metal complexes for efficient iodine adsorption in water.

Environ Sci Pollut Res Int. 2021 Feb 06;:

Authors: Qin J, Zhang W, Chen Y, Liu R, Fan Y

Abstract
Radioactive iodine is extremely harmful to the environment, and it is of great significance to develop materials that efficiently remove iodine. We prepared two triazole metal complexes with simple method, denoted as Zn(tr)(OAc) and Zn(ttr)(OAc), which were used to adsorb iodine from aqueous solution. The properties and adsorption mechanism of the two materials were studied by different techniques including XRD, SEM, N2 porosimetry at 77 K, FTIR, TGA, elemental analysis (EDS), and X-ray photoelectron spectroscopy (XPS). The results showed that both materials had good water and thermal stability. Pseudo-second-order kinetic model was better at describing the iodine adsorption kinetics onto the adsorbents. It was proved that chemical adsorption dominated, iodine mainly enriched on the materials in the form of I3-1. Zn(ttr)(OAc) had a higher adsorption capacity than Zn(tr)(OAc) due to the electron-donating group -NH2. The maximum adsorption capacity of the two materials for iodine reached 714.501 mg·g-1 and 846.108 mg·g-1 at 25 °C.

PMID: 33548041 [PubMed - as supplied by publisher]

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Free Flap Reconstruction in a Tongue Cancer Patient with Nephrotic Syndrome: A Case Report

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Abstract

Free flap has become crucial for reconstruction in head and neck oncology post resection since the time of its advent. It has shown a high success rate and provides a better quality of life over loco regional flaps. Literature has shown the success of free flaps does get influenced by preexisting medical conditions of the patient. Nephrotic syndrome being a hypercoagulable state doesn't find much mention in literature and its effect on free flaps has been less studied. Hence, using a free flap in such condition creates a decision making dilemma. Here we present a case report to show the feasibility of such flaps in nephrotic syndrome patients under structured environment successfully.

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Acupoint-brain (acubrain) mapping: Common and distinct cortical language regions activated by focused ultrasound stimulation on two language-relevant acupoints

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Publication date: April 2021

Source: Brain and Language, Volume 215

Author(s): Di Yuan, Haoyue Tian, Yulong Zhou, Jinjian Wu, Tong Sun, Zhuoni Xiao, Chunfeng Shang, Jiaojian Wang, Xin Chen, Yimin Sun, Joey Tang, Shijun Qiu, Li Hai Tan

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Cranial aseptic osteomyelitis associated with pyoderma gangrenosum.

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Cranial aseptic osteomyelitis associated with pyoderma gangrenosum.

Neurocirugia (Astur). 2021 Feb 02;:

Authors: Piqué-Durán E, Morera Molina J, Limeres-González MÁ, Espejo-Gil AM

Abstract
Neutrophilic dermatoses include a heterogeneous group of entities. Uncommonly, they can accumulate aseptic neutrophilic abscesses in other tissues in addition to the skin. A 34-year-old female complained of a headache which was unresponsive to usual drugs. A TAC revealed an osteolytic lesion in the right parietal bone. The biopsy showed osteomyelitis. One year later, pyoderma gangrenosum appeared in the anterior aspect of both legs. The headache and the cutaneous lesions disappeared after treatment with oral prednisone. The bone involvement in the background of neutrophilic dermatoses is exceptional. Usually, it involves children in the context of chronic recurrent multiple osteomyelitis (CRMO). Only two cases have been described in adults. One of them was a 26-year-old woman who had had CRMO since childhood, and the other one in contiguity with the cutaneous lesions of pyoderma gangrenosum.

PMID: 33546980 [PubMed - as supplied by publisher]

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