OtoRhinoLaryngology by Sfakianakis G.Alexandros Sfakianakis G.Alexandros,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174
Παρασκευή 2 Νοεμβρίου 2018
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere’s disease from BPPV: clinical validation using a double-blind approach
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere’s disease from BPPV: clinical validation using a double-blind approach
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients
Verb Variability and Morphosyntactic Priming With Typically Developing 2- and 3-Year-Olds
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Structural Relationship Between Cognitive Processing and Syntactic Sentence Comprehension in Children With and Without Developmental Language Disorder
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Minimally Detectable Change and Minimal Clinically Important Difference of a Decline in Sentence Intelligibility and Speaking Rate for Individuals With Amyotrophic Lateral Sclerosis
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Treating Speech Movement Hypokinesia in Parkinson's Disease: Does Movement Size Matter?
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Verb Variability and Morphosyntactic Priming With Typically Developing 2- and 3-Year-Olds
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Structural Relationship Between Cognitive Processing and Syntactic Sentence Comprehension in Children With and Without Developmental Language Disorder
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Minimally Detectable Change and Minimal Clinically Important Difference of a Decline in Sentence Intelligibility and Speaking Rate for Individuals With Amyotrophic Lateral Sclerosis
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Treating Speech Movement Hypokinesia in Parkinson's Disease: Does Movement Size Matter?
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Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Related Articles |
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Singh NK, Barman A
Abstract
The study aimed at examining the usefulness of inter-frequency amplitude ratio (IFAR) of ocular vestibular evoked myogenic potential (oVEMP) in identifying Meniere's disease (MD) and differentiating it from benign paroxysmal positional vertigo (BPPV). A case-control design was used with a double blind approach. Phase 1 included 70 healthy individuals and 36 individuals each with MD and BPPV and Phase 2 included 20 individuals each with MD and BPPV. The age range of the participants in both phases was 15-50 years. All participants underwent oVEMP testing using 500 and 1000 Hz tone bursts and IFAR was obtained. The results in phase 1 revealed significantly higher IFARs in Meniere's disease than BPPV and healthy individuals (p < 0.001). An optimum criterion point of IFAR ≥1.11 for diagnosing MD was found which yielded 80% sensitivity and 98% specificity. The results in phase 2 demonstrated 85% correct identification of MD and 95% correct rejection of BPPV as non-MD. IFAR of oVEMP appears highly sensitive and specific parameter for identifying MD and a clinically valid tool for differentiating MD from BPPV.
PMID: 30382796 [PubMed - as supplied by publisher]
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Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Related Articles |
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Gleser MA, Zettner EM
Abstract
OBJECTIVE: Identify hearing effects of a single course of intravenous (IV) aminoglycoside antibiotics (AGs) therapy in adult cystic fibrosis (CF) patients. Determine whether the change is large enough to enable a proof-of-concept study of a new drug preventing AG-associated hearing loss.
DESIGN: Retrospective case review of CF patients with sequential audiograms ± an intervening course of IV AG therapy.
STUDY SAMPLE: 84 patients with no intervening IV AG treatment, 38 patients undergoing a single course of IV AGs.
RESULTS: Using ASHA ototoxicity metrics, 45% of adult CF patients in the Single-IV group met the criteria for ototoxicity compared to 23% of the No-IV patients. Other hearing metrics including the average maximal threshold shift (TS) and average high frequency TS showed highly significant differences between groups. Testing only participants with mild or greater pre-therapy high frequency hearing loss further increased the differences between the two groups by every metric tested.
CONCLUSION: Adult CF patients exposed to a single course of IV AGs have significantly greater TS than patients without IV AG exposure. Patients with mild to moderate hearing loss prior to AG-IVs are at increased risk of developing ototoxicity from subsequent parenteral AG therapy.
PMID: 30382794 [PubMed - as supplied by publisher]
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Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Related Articles |
Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Int J Audiol. 2018 Nov 01;:1-7
Authors: Cramer JL, Donai JJ
Abstract
The purpose of this study was to assess the effects of signal bandwidth, noise and signal predictability on listening effort among younger and middle-aged individuals with normal hearing, where YNH = young normal hearing and ONH = older normal hearing. It was of interest to determine if a reduction in high-frequency energy would differentially influence performance between the two groups. A mixed-model design was used, where listening effort, word identification and effort ratings served as the within-subject factors and listener group served as the between-subject factor. Twenty listeners aged 18-25 years (YNH group) and 20 listeners aged 40-55 years (ONH group) participated in the experiment. Results showed significantly poorer word recall and significantly higher perceived effort among the ONH group. Increasing the signal bandwidth from 2 to 8 kHz significantly improved word recall and decreased listening effort ratings. Effort ratings from both groups matched word recall performance in that when word recall was lower perceived effort was higher and when word recall was higher perceived effort was lower. In general, providing additional high-frequency energy up to 8 kHz reduced listening effort among both groups of listeners. However, the ONH group, experienced additional effort when completing the tasks.
PMID: 30382793 [PubMed - as supplied by publisher]
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Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Related Articles |
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Singh NK, Barman A
Abstract
The study aimed at examining the usefulness of inter-frequency amplitude ratio (IFAR) of ocular vestibular evoked myogenic potential (oVEMP) in identifying Meniere's disease (MD) and differentiating it from benign paroxysmal positional vertigo (BPPV). A case-control design was used with a double blind approach. Phase 1 included 70 healthy individuals and 36 individuals each with MD and BPPV and Phase 2 included 20 individuals each with MD and BPPV. The age range of the participants in both phases was 15-50 years. All participants underwent oVEMP testing using 500 and 1000 Hz tone bursts and IFAR was obtained. The results in phase 1 revealed significantly higher IFARs in Meniere's disease than BPPV and healthy individuals (p < 0.001). An optimum criterion point of IFAR ≥1.11 for diagnosing MD was found which yielded 80% sensitivity and 98% specificity. The results in phase 2 demonstrated 85% correct identification of MD and 95% correct rejection of BPPV as non-MD. IFAR of oVEMP appears highly sensitive and specific parameter for identifying MD and a clinically valid tool for differentiating MD from BPPV.
PMID: 30382796 [PubMed - as supplied by publisher]
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Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Related Articles |
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Gleser MA, Zettner EM
Abstract
OBJECTIVE: Identify hearing effects of a single course of intravenous (IV) aminoglycoside antibiotics (AGs) therapy in adult cystic fibrosis (CF) patients. Determine whether the change is large enough to enable a proof-of-concept study of a new drug preventing AG-associated hearing loss.
DESIGN: Retrospective case review of CF patients with sequential audiograms ± an intervening course of IV AG therapy.
STUDY SAMPLE: 84 patients with no intervening IV AG treatment, 38 patients undergoing a single course of IV AGs.
RESULTS: Using ASHA ototoxicity metrics, 45% of adult CF patients in the Single-IV group met the criteria for ototoxicity compared to 23% of the No-IV patients. Other hearing metrics including the average maximal threshold shift (TS) and average high frequency TS showed highly significant differences between groups. Testing only participants with mild or greater pre-therapy high frequency hearing loss further increased the differences between the two groups by every metric tested.
CONCLUSION: Adult CF patients exposed to a single course of IV AGs have significantly greater TS than patients without IV AG exposure. Patients with mild to moderate hearing loss prior to AG-IVs are at increased risk of developing ototoxicity from subsequent parenteral AG therapy.
PMID: 30382794 [PubMed - as supplied by publisher]
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via IFTTT
Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Related Articles |
Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Int J Audiol. 2018 Nov 01;:1-7
Authors: Cramer JL, Donai JJ
Abstract
The purpose of this study was to assess the effects of signal bandwidth, noise and signal predictability on listening effort among younger and middle-aged individuals with normal hearing, where YNH = young normal hearing and ONH = older normal hearing. It was of interest to determine if a reduction in high-frequency energy would differentially influence performance between the two groups. A mixed-model design was used, where listening effort, word identification and effort ratings served as the within-subject factors and listener group served as the between-subject factor. Twenty listeners aged 18-25 years (YNH group) and 20 listeners aged 40-55 years (ONH group) participated in the experiment. Results showed significantly poorer word recall and significantly higher perceived effort among the ONH group. Increasing the signal bandwidth from 2 to 8 kHz significantly improved word recall and decreased listening effort ratings. Effort ratings from both groups matched word recall performance in that when word recall was lower perceived effort was higher and when word recall was higher perceived effort was lower. In general, providing additional high-frequency energy up to 8 kHz reduced listening effort among both groups of listeners. However, the ONH group, experienced additional effort when completing the tasks.
PMID: 30382793 [PubMed - as supplied by publisher]
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Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Singh NK, Barman A
Abstract
The study aimed at examining the usefulness of inter-frequency amplitude ratio (IFAR) of ocular vestibular evoked myogenic potential (oVEMP) in identifying Meniere's disease (MD) and differentiating it from benign paroxysmal positional vertigo (BPPV). A case-control design was used with a double blind approach. Phase 1 included 70 healthy individuals and 36 individuals each with MD and BPPV and Phase 2 included 20 individuals each with MD and BPPV. The age range of the participants in both phases was 15-50 years. All participants underwent oVEMP testing using 500 and 1000 Hz tone bursts and IFAR was obtained. The results in phase 1 revealed significantly higher IFARs in Meniere's disease than BPPV and healthy individuals (p < 0.001). An optimum criterion point of IFAR ≥1.11 for diagnosing MD was found which yielded 80% sensitivity and 98% specificity. The results in phase 2 demonstrated 85% correct identification of MD and 95% correct rejection of BPPV as non-MD. IFAR of oVEMP appears highly sensitive and specific parameter for identifying MD and a clinically valid tool for differentiating MD from BPPV.
PMID: 30382796 [PubMed - as supplied by publisher]
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via IFTTT
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Gleser MA, Zettner EM
Abstract
OBJECTIVE: Identify hearing effects of a single course of intravenous (IV) aminoglycoside antibiotics (AGs) therapy in adult cystic fibrosis (CF) patients. Determine whether the change is large enough to enable a proof-of-concept study of a new drug preventing AG-associated hearing loss.
DESIGN: Retrospective case review of CF patients with sequential audiograms ± an intervening course of IV AG therapy.
STUDY SAMPLE: 84 patients with no intervening IV AG treatment, 38 patients undergoing a single course of IV AGs.
RESULTS: Using ASHA ototoxicity metrics, 45% of adult CF patients in the Single-IV group met the criteria for ototoxicity compared to 23% of the No-IV patients. Other hearing metrics including the average maximal threshold shift (TS) and average high frequency TS showed highly significant differences between groups. Testing only participants with mild or greater pre-therapy high frequency hearing loss further increased the differences between the two groups by every metric tested.
CONCLUSION: Adult CF patients exposed to a single course of IV AGs have significantly greater TS than patients without IV AG exposure. Patients with mild to moderate hearing loss prior to AG-IVs are at increased risk of developing ototoxicity from subsequent parenteral AG therapy.
PMID: 30382794 [PubMed - as supplied by publisher]
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Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Int J Audiol. 2018 Nov 01;:1-7
Authors: Cramer JL, Donai JJ
Abstract
The purpose of this study was to assess the effects of signal bandwidth, noise and signal predictability on listening effort among younger and middle-aged individuals with normal hearing, where YNH = young normal hearing and ONH = older normal hearing. It was of interest to determine if a reduction in high-frequency energy would differentially influence performance between the two groups. A mixed-model design was used, where listening effort, word identification and effort ratings served as the within-subject factors and listener group served as the between-subject factor. Twenty listeners aged 18-25 years (YNH group) and 20 listeners aged 40-55 years (ONH group) participated in the experiment. Results showed significantly poorer word recall and significantly higher perceived effort among the ONH group. Increasing the signal bandwidth from 2 to 8 kHz significantly improved word recall and decreased listening effort ratings. Effort ratings from both groups matched word recall performance in that when word recall was lower perceived effort was higher and when word recall was higher perceived effort was lower. In general, providing additional high-frequency energy up to 8 kHz reduced listening effort among both groups of listeners. However, the ONH group, experienced additional effort when completing the tasks.
PMID: 30382793 [PubMed - as supplied by publisher]
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Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Inter-frequency amplitude ratio of oVEMP for differentiating Meniere's disease from BPPV: clinical validation using a double-blind approach.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Singh NK, Barman A
Abstract
The study aimed at examining the usefulness of inter-frequency amplitude ratio (IFAR) of ocular vestibular evoked myogenic potential (oVEMP) in identifying Meniere's disease (MD) and differentiating it from benign paroxysmal positional vertigo (BPPV). A case-control design was used with a double blind approach. Phase 1 included 70 healthy individuals and 36 individuals each with MD and BPPV and Phase 2 included 20 individuals each with MD and BPPV. The age range of the participants in both phases was 15-50 years. All participants underwent oVEMP testing using 500 and 1000 Hz tone bursts and IFAR was obtained. The results in phase 1 revealed significantly higher IFARs in Meniere's disease than BPPV and healthy individuals (p < 0.001). An optimum criterion point of IFAR ≥1.11 for diagnosing MD was found which yielded 80% sensitivity and 98% specificity. The results in phase 2 demonstrated 85% correct identification of MD and 95% correct rejection of BPPV as non-MD. IFAR of oVEMP appears highly sensitive and specific parameter for identifying MD and a clinically valid tool for differentiating MD from BPPV.
PMID: 30382796 [PubMed - as supplied by publisher]
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via IFTTT
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Negative hearing effects of a single course of IV aminoglycoside therapy in cystic fibrosis patients.
Int J Audiol. 2018 Nov 01;:1-8
Authors: Gleser MA, Zettner EM
Abstract
OBJECTIVE: Identify hearing effects of a single course of intravenous (IV) aminoglycoside antibiotics (AGs) therapy in adult cystic fibrosis (CF) patients. Determine whether the change is large enough to enable a proof-of-concept study of a new drug preventing AG-associated hearing loss.
DESIGN: Retrospective case review of CF patients with sequential audiograms ± an intervening course of IV AG therapy.
STUDY SAMPLE: 84 patients with no intervening IV AG treatment, 38 patients undergoing a single course of IV AGs.
RESULTS: Using ASHA ototoxicity metrics, 45% of adult CF patients in the Single-IV group met the criteria for ototoxicity compared to 23% of the No-IV patients. Other hearing metrics including the average maximal threshold shift (TS) and average high frequency TS showed highly significant differences between groups. Testing only participants with mild or greater pre-therapy high frequency hearing loss further increased the differences between the two groups by every metric tested.
CONCLUSION: Adult CF patients exposed to a single course of IV AGs have significantly greater TS than patients without IV AG exposure. Patients with mild to moderate hearing loss prior to AG-IVs are at increased risk of developing ototoxicity from subsequent parenteral AG therapy.
PMID: 30382794 [PubMed - as supplied by publisher]
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Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Effects of signal bandwidth on listening effort in young- and middle-aged adults.
Int J Audiol. 2018 Nov 01;:1-7
Authors: Cramer JL, Donai JJ
Abstract
The purpose of this study was to assess the effects of signal bandwidth, noise and signal predictability on listening effort among younger and middle-aged individuals with normal hearing, where YNH = young normal hearing and ONH = older normal hearing. It was of interest to determine if a reduction in high-frequency energy would differentially influence performance between the two groups. A mixed-model design was used, where listening effort, word identification and effort ratings served as the within-subject factors and listener group served as the between-subject factor. Twenty listeners aged 18-25 years (YNH group) and 20 listeners aged 40-55 years (ONH group) participated in the experiment. Results showed significantly poorer word recall and significantly higher perceived effort among the ONH group. Increasing the signal bandwidth from 2 to 8 kHz significantly improved word recall and decreased listening effort ratings. Effort ratings from both groups matched word recall performance in that when word recall was lower perceived effort was higher and when word recall was higher perceived effort was lower. In general, providing additional high-frequency energy up to 8 kHz reduced listening effort among both groups of listeners. However, the ONH group, experienced additional effort when completing the tasks.
PMID: 30382793 [PubMed - as supplied by publisher]
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KINESIOPHOBIA, BUT NOT STRENGTH IS ASSOCIATED WITH ALTERED MOVEMENT IN WOMEN WITH PATELLOFEMORAL PAIN
Publication date: Available online 1 November 2018
Source: Gait & Posture
Author(s): Danilo de Oliveira Silva, Christian John Barton, Ronaldo Valdir Briani, Bianca Taborda, Amanda Schenatto Ferreira, Marcella Ferraz Pazzinatto, Fábio Mícolis de Azevedo
Abstract
Background
Evidence indicates the presence of both kinesiophobia and knee extension strength deficits in women with patellofemoral pain (PFP). Both impairments may contribute to apparent compensatory gait patterns including reduced cadence and peak knee flexion during stair negotiation.
Research question
Is kinesiophobia or knee extension strength associated with movement pattern in women with patellofemoral pain?
Methods
Forty women with PFP were assessed with three-dimensional kinematic analyses during stair descent; isokinetic dynamometry of the knee extensors (isometric, concentric and eccentric); and the Tampa scale for kinesiophobia. Pearson coefficients were calculated to determine relationship among variables.
Results
Kinesiophobia correlated significantly with cadence (r = -0.62, p < 0.001), and peak knee flexion (r = -0.76, p < 0.001). No significant correlations were found between any knee extensor strength variables and kinematics (cadence or peak knee flexion); or kinesiophobia (p > 0.05).
Significance
Findings of this study could suggest addressing strength impairments alone may not adequately address kinesiophobia and movement pattern impairments in women with PFP. However, high-quality randomised controlled trials are needed to test this assumption. Further value may be added if currently evidence-based knee strengthening exercise is combined with education and/or graded exposure to address kinesiophobia, and consideration to gait retraining to address altered movement patterns at the knee.
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KINESIOPHOBIA, BUT NOT STRENGTH IS ASSOCIATED WITH ALTERED MOVEMENT IN WOMEN WITH PATELLOFEMORAL PAIN
Publication date: Available online 1 November 2018
Source: Gait & Posture
Author(s): Danilo de Oliveira Silva, Christian John Barton, Ronaldo Valdir Briani, Bianca Taborda, Amanda Schenatto Ferreira, Marcella Ferraz Pazzinatto, Fábio Mícolis de Azevedo
Abstract
Background
Evidence indicates the presence of both kinesiophobia and knee extension strength deficits in women with patellofemoral pain (PFP). Both impairments may contribute to apparent compensatory gait patterns including reduced cadence and peak knee flexion during stair negotiation.
Research question
Is kinesiophobia or knee extension strength associated with movement pattern in women with patellofemoral pain?
Methods
Forty women with PFP were assessed with three-dimensional kinematic analyses during stair descent; isokinetic dynamometry of the knee extensors (isometric, concentric and eccentric); and the Tampa scale for kinesiophobia. Pearson coefficients were calculated to determine relationship among variables.
Results
Kinesiophobia correlated significantly with cadence (r = -0.62, p < 0.001), and peak knee flexion (r = -0.76, p < 0.001). No significant correlations were found between any knee extensor strength variables and kinematics (cadence or peak knee flexion); or kinesiophobia (p > 0.05).
Significance
Findings of this study could suggest addressing strength impairments alone may not adequately address kinesiophobia and movement pattern impairments in women with PFP. However, high-quality randomised controlled trials are needed to test this assumption. Further value may be added if currently evidence-based knee strengthening exercise is combined with education and/or graded exposure to address kinesiophobia, and consideration to gait retraining to address altered movement patterns at the knee.
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