Haider W Alsarhan, Mohammed R Dawood, Abd Alhussen Kareem Jwery, Ammar H Khammas, Abbas K Hamad
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):16-19
Background Tympanic membrane perforation is a common problem and causes hearing disability, and many factors can affect the degree of hearing loss. Objective The aim of this study was to assess the degree of hearing loss in relation with the size and site of tympanic membrane perforation. Patients and methods This prospective study was conducted at Al-Yarmouk Teaching Hospital during the period from February 2015 to February 2016 on 75 patients (93 ears) with tympanic membrane perforations. The size and site of perforations were evaluated under the microscope and classified according to the size (small, moderate, and large), and the site (anteroinferior, anterosuperior, posteroinferior, and posterosuperior quadrants). Hearing loss was measured in each case with pure-tone audiometry and its relation with these parameters was analyzed. Results There was an increase in hearing loss with the increase in the size of perforation. Perforation locations had an impact on hearing loss; this was statistically significant, especially in the posteroinferior quadrant if compared with other quadrants, as P value was 0.037. Conclusion The size and site of tympanic membrane perforation had a significant effect on the magnitude of hearing loss.
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Τετάρτη 28 Σεπτεμβρίου 2016
Evaluation of factors that influence cochlear implant performance
Vergena S Ahmed Elkayal, Mona I Mourad, Manal M Elbanna, Mohamed A Mohamed Talaat
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
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Early detection of changes to hearing status attributed to treatment regimen with ototoxicity in the state of Qatar
Zainab Al Musleh, Maha Al Suliteen, Khalid Hadi, Maysoun El Abbadi, Waleed Omar, Awatif Ali, Amna Al Amin, Muna Alsufi, Nehal Alnajar, Nawal Ahmed
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Les premières rencontres d'ORL et d'oto-neurochirurgie. Bejaia 17-18 septembre 2015, Auditorium Targa Ouzemour; Université Abd Errahmane Mira Bejaia, The 1st ENT and skull base surgery meeting of Bejaia 17-18 September Programme
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):20-23
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Assessment of hearing loss in tympanic membrane perforation
Haider W Alsarhan, Mohammed R Dawood, Abd Alhussen Kareem Jwery, Ammar H Khammas, Abbas K Hamad
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):16-19
Background Tympanic membrane perforation is a common problem and causes hearing disability, and many factors can affect the degree of hearing loss. Objective The aim of this study was to assess the degree of hearing loss in relation with the size and site of tympanic membrane perforation. Patients and methods This prospective study was conducted at Al-Yarmouk Teaching Hospital during the period from February 2015 to February 2016 on 75 patients (93 ears) with tympanic membrane perforations. The size and site of perforations were evaluated under the microscope and classified according to the size (small, moderate, and large), and the site (anteroinferior, anterosuperior, posteroinferior, and posterosuperior quadrants). Hearing loss was measured in each case with pure-tone audiometry and its relation with these parameters was analyzed. Results There was an increase in hearing loss with the increase in the size of perforation. Perforation locations had an impact on hearing loss; this was statistically significant, especially in the posteroinferior quadrant if compared with other quadrants, as P value was 0.037. Conclusion The size and site of tympanic membrane perforation had a significant effect on the magnitude of hearing loss.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):16-19
Background Tympanic membrane perforation is a common problem and causes hearing disability, and many factors can affect the degree of hearing loss. Objective The aim of this study was to assess the degree of hearing loss in relation with the size and site of tympanic membrane perforation. Patients and methods This prospective study was conducted at Al-Yarmouk Teaching Hospital during the period from February 2015 to February 2016 on 75 patients (93 ears) with tympanic membrane perforations. The size and site of perforations were evaluated under the microscope and classified according to the size (small, moderate, and large), and the site (anteroinferior, anterosuperior, posteroinferior, and posterosuperior quadrants). Hearing loss was measured in each case with pure-tone audiometry and its relation with these parameters was analyzed. Results There was an increase in hearing loss with the increase in the size of perforation. Perforation locations had an impact on hearing loss; this was statistically significant, especially in the posteroinferior quadrant if compared with other quadrants, as P value was 0.037. Conclusion The size and site of tympanic membrane perforation had a significant effect on the magnitude of hearing loss.
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Evaluation of factors that influence cochlear implant performance
Vergena S Ahmed Elkayal, Mona I Mourad, Manal M Elbanna, Mohamed A Mohamed Talaat
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
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Early detection of changes to hearing status attributed to treatment regimen with ototoxicity in the state of Qatar
Zainab Al Musleh, Maha Al Suliteen, Khalid Hadi, Maysoun El Abbadi, Waleed Omar, Awatif Ali, Amna Al Amin, Muna Alsufi, Nehal Alnajar, Nawal Ahmed
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Les premières rencontres d'ORL et d'oto-neurochirurgie. Bejaia 17-18 septembre 2015, Auditorium Targa Ouzemour; Université Abd Errahmane Mira Bejaia, The 1st ENT and skull base surgery meeting of Bejaia 17-18 September Programme
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):20-23
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Assessment of hearing loss in tympanic membrane perforation
Haider W Alsarhan, Mohammed R Dawood, Abd Alhussen Kareem Jwery, Ammar H Khammas, Abbas K Hamad
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):16-19
Background Tympanic membrane perforation is a common problem and causes hearing disability, and many factors can affect the degree of hearing loss. Objective The aim of this study was to assess the degree of hearing loss in relation with the size and site of tympanic membrane perforation. Patients and methods This prospective study was conducted at Al-Yarmouk Teaching Hospital during the period from February 2015 to February 2016 on 75 patients (93 ears) with tympanic membrane perforations. The size and site of perforations were evaluated under the microscope and classified according to the size (small, moderate, and large), and the site (anteroinferior, anterosuperior, posteroinferior, and posterosuperior quadrants). Hearing loss was measured in each case with pure-tone audiometry and its relation with these parameters was analyzed. Results There was an increase in hearing loss with the increase in the size of perforation. Perforation locations had an impact on hearing loss; this was statistically significant, especially in the posteroinferior quadrant if compared with other quadrants, as P value was 0.037. Conclusion The size and site of tympanic membrane perforation had a significant effect on the magnitude of hearing loss.
from #Audiology via ola Kala on Inoreader http://ift.tt/2d619nc
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):16-19
Background Tympanic membrane perforation is a common problem and causes hearing disability, and many factors can affect the degree of hearing loss. Objective The aim of this study was to assess the degree of hearing loss in relation with the size and site of tympanic membrane perforation. Patients and methods This prospective study was conducted at Al-Yarmouk Teaching Hospital during the period from February 2015 to February 2016 on 75 patients (93 ears) with tympanic membrane perforations. The size and site of perforations were evaluated under the microscope and classified according to the size (small, moderate, and large), and the site (anteroinferior, anterosuperior, posteroinferior, and posterosuperior quadrants). Hearing loss was measured in each case with pure-tone audiometry and its relation with these parameters was analyzed. Results There was an increase in hearing loss with the increase in the size of perforation. Perforation locations had an impact on hearing loss; this was statistically significant, especially in the posteroinferior quadrant if compared with other quadrants, as P value was 0.037. Conclusion The size and site of tympanic membrane perforation had a significant effect on the magnitude of hearing loss.
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via IFTTT
Evaluation of factors that influence cochlear implant performance
Vergena S Ahmed Elkayal, Mona I Mourad, Manal M Elbanna, Mohamed A Mohamed Talaat
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):1-8
Background One of the primary goals of cochlear implantation is open-set auditory-only speech understanding in everyday listening environments. An understanding of the etiology and neurocognitive factors that contribute to a favorable outcome after cochlear implantation would potentially allow clinicians to predict the results for a cochlear implant patient. The ability to discriminate small acoustic differences is very important for the perception and processing of speech signals. The mismatch negativity (MMN) method is an objective tool that provides a measure of automatic stimuli discrimination. Objective of the study The aim of this study was to classify the communicative performance of children with cochlear implants and verify this outcome by means of electrophysiological biomarkers. Methods The study was carried out in three phases: phase I included completing an audiological data information sheet for all patients, with data taken from their records, which included demographic data, preoperative and postoperative audiological evaluation, operative detailed information, cochlear implant mapping data, and preoperative auditory verbal therapy details as regards regularity and benefit. Phase II involved classifying the patients’ communicative performance according to a phoniatric evaluation protocol into poor, fair, and good response, determining behavioral pure tone aided thresholds with their cochlear implants, and conducting electrophysiological studies ‘P1 and MMN’ for those with aided thresholds in the long-term average speech spectrum with their cochlear implant. Phase III entailed verification of factors that affect the outcome of all cochlear implant users. Results Age of cochlear implantation, cause of hearing loss, comorbidity, preoperative electrophysiological test results, and radiological findings are variables affecting cochlear implant performance and affecting the patient's communicative performance, whereas sex of the patient and number of stimulated electrodes are variables not affecting the cochlear implant performance. Conclusion Early cochlear implantation and good auditory verbal therapy have better outcomes as regards listening and communication skills. Cortical auditory evoked potential (P1) and MMN might provide a clinical tool to monitor aural rehabilitation outcome. These objective electrophysiological parameters may also be used as prognostic indicators for speech and language outcome.
from #Audiology via ola Kala on Inoreader http://ift.tt/2duRUPU
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Early detection of changes to hearing status attributed to treatment regimen with ototoxicity in the state of Qatar
Zainab Al Musleh, Maha Al Suliteen, Khalid Hadi, Maysoun El Abbadi, Waleed Omar, Awatif Ali, Amna Al Amin, Muna Alsufi, Nehal Alnajar, Nawal Ahmed
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):9-15
Background Ototoxicity resulting from cisplatin chemotherapy constitutes a significant clinical problem and challenge. Therefore, an early and effective detection of hearing loss in pediatric oncology patients receiving ototoxic medication and early intervention are critical to help these patients in achieving these developmental milestones and improving their quality of life. Materials and methods This prospective, observational study was designed as an initial pilot study to collect and analyze data from January 2014 to January 2015 on a variety of parameters. All pediatric patients, aged less than 14 years, referred from the Pediatric Hematology/Oncology Clinic to the new Ototoxic Clinic were included in the study. Descriptive statistics were used to summarize the above data, and associations between two or more qualitative variables were assessed using the χ2-test or Fisher's exact test as appropriate. Results A total of 20 patients were included in the study. Diagnostic otoacoustic emission findings were found to be normal in 14 patients (80%); four patients (20%) had abnormal findings, and in two cases this test was not carried out. High-frequency audiometry test indicated that nine (52.9%) patients had normal findings, whereas five (29.4%) had abnormal results. High-frequency audiometry could not be carried out for six (30%) patients because of their ages. Hearing loss involving the speech frequencies affected only two patients (10%; 95% confidence interval 1.7–29.3); they were diagnosed to have β-thalassemia and retinoblastoma and are currently using xjade and cisplatin. Conclusion Early and effective identification of ototoxicity is vital in children receiving cancer treatments because of the impact acquired hearing loss has on social and educational outcomes in children. This study highlights the role of early detection of hearing loss in pediatric patient receiving ototoxic medication and of possible potential interventions to enhance their quality of life during and after treatment.
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Les premières rencontres d'ORL et d'oto-neurochirurgie. Bejaia 17-18 septembre 2015, Auditorium Targa Ouzemour; Université Abd Errahmane Mira Bejaia, The 1st ENT and skull base surgery meeting of Bejaia 17-18 September Programme
Advanced Arab Academy of Audio-Vestibulogy Journal 2016 3(1):20-23
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20th Anniversary JDP-LCD student colloquium a huge success!
The 20th Annual Doctoral Student Colloquium of the SDSU/UCSD Joint Doctoral Program in Language and Communicative Disorders (JDP-LCD), on September 23, 2016, was a big success!
- See the speaker abstracts (docx).
Pictured (L-R) are JDP-LCD students who presented research from their 1st and 2nd year doctoral projects: Erin Smolak, Philip Combiths, Brittany Lee, and Gabriela Meade.
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20th Anniversary JDP-LCD student colloquium a huge success!
The 20th Annual Doctoral Student Colloquium of the SDSU/UCSD Joint Doctoral Program in Language and Communicative Disorders (JDP-LCD), on September 23, 2016, was a big success!
- See the speaker abstracts (docx).
Pictured (L-R) are JDP-LCD students who presented research from their 1st and 2nd year doctoral projects: Erin Smolak, Philip Combiths, Brittany Lee, and Gabriela Meade.
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20th Anniversary JDP-LCD student colloquium a huge success!
The 20th Annual Doctoral Student Colloquium of the SDSU/UCSD Joint Doctoral Program in Language and Communicative Disorders (JDP-LCD), on September 23, 2016, was a big success!
- See the speaker abstracts (docx).
Pictured (L-R) are JDP-LCD students who presented research from their 1st and 2nd year doctoral projects: Erin Smolak, Philip Combiths, Brittany Lee, and Gabriela Meade.
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Profiles of Stimulus-Frequency Otoacoustic Emissions from 0.5 to 20 kHz in Humans
ABSTRACT
The characteristics of human otoacoustic emissions (OAEs) have not been thoroughly examined above the standard audiometric frequency range (>8 kHz). This is despite the fact that deterioration of cochlear function often starts at the basal, high-frequency end of the cochlea before progressing apically. Here, stimulus-frequency OAEs (SFOAEs) were obtained from 0.5 to 20 kHz in 23 young, audiometrically normal female adults and three individuals with abnormal audiograms, using a low-to-moderate probe level of 36 dB forward pressure level (FPL). In audiometrically normal ears, SFOAEs were measurable at frequencies approaching the start of the steeply sloping high-frequency portion of the audiogram (∼12–15 kHz), though their amplitudes often declined substantially above ∼7 kHz, rarely exceeding 0 dB SPL above 8 kHz. This amplitude decline was typically abrupt and occurred at a frequency that was variable across subjects and not strongly related to the audiogram. In contrast, certain ears with elevated mid-frequency thresholds but regions of normal high-frequency sensitivity could possess surprisingly large SFOAEs (>10 dB SPL) above 7 kHz. When also measured, distortion-product OAEs (DPOAEs) usually remained stronger at higher stimulus frequencies and mirrored the audiogram more closely than SFOAEs. However, the high-frequency extent of SFOAE and DPOAE responses was similar when compared as a function of the response frequency, suggesting that middle ear transmission may be a common limiting factor at high frequencies. Nevertheless, cochlear factors are more likely responsible for complexities observed in high-frequency SFOAE spectra, such as abrupt amplitude changes and narrowly defined response peaks above 10 kHz, as well as the large responses in abnormal ears. These factors may include altered cochlear reflectivity due to subtle damage or the reduced spatial extent of the SFOAE generation region at the cochlear base. The use of higher probe levels is necessary to further evaluate the characteristics and potential utility of high-frequency SFOAE measurements.
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Hearing in Noisy Listening Environments
An article published on September 26 in the Wall Street Journal addressed a challenge many aging Baby Boomers face on a daily basis—difficulty hearing in noisy listening environments, despite the absence of measurable audiometric hearing loss. This condition has been referred to as “hidden hearing loss,” and is thought to reflect cochlear synaptopathy or damage to the synaptic junction between cochlear hair cells and the auditory nerve.
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The influence of the aquatic environment on the control of postural sway
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Asymmetry in gait pattern following tibial shaft fractures − a prospective one-year follow-up study of 49 patients
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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The influence of the aquatic environment on the control of postural sway
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Asymmetry in gait pattern following tibial shaft fractures − a prospective one-year follow-up study of 49 patients
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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The influence of the aquatic environment on the control of postural sway
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Source:Gait & Posture
Author(s): Andresa R. Marinho-Buzelli, Hossein Rouhani, Kei Masani, Mary C. Verrier, Milos R. Popovic
Balance training in the aquatic environment is often used in rehabilitation practice to improve static and dynamic balance. Although aquatic therapy is widely used in clinical practice, we still lack evidence on how immersion in water actually impacts postural control. We examined how postural sway measured using centre of pressure and trunk acceleration parameters are influenced by the aquatic environment along with the effects of visual information. Our results suggest that the aquatic environment increases postural instability, measured by the centre of pressure parameters in the time-domain. The mean velocity and area were more significantly affected when individuals stood with eyes closed in the aquatic environment. In addition, a more forward posture was assumed in water with eyes closed in comparison to standing on land. In water, the low frequencies of sway were more dominant compared to standing on dry land. Trunk acceleration differed in water and dry land only for the larger upper trunk acceleration in mediolateral direction during standing in water. This finding shows that the study participants potentially resorted to using their upper trunk to compensate for postural instability in mediolateral direction. Only the lower trunk seemed to change acceleration pattern in anteroposterior and mediolateral directions when the eyes were closed, and it did so depending on the environment conditions. The increased postural instability and the change in postural control strategies that the aquatic environment offers may be a beneficial stimulus for improving balance control.
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Asymmetry in gait pattern following tibial shaft fractures − a prospective one-year follow-up study of 49 patients
Publication date: Available online 28 September 2016
Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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Source:Gait & Posture
Author(s): Peter Larsen, Uffe Laessoe, Sten Rasmussen, Thomas Graven-Nielsen, Christian Berre Eriksen, Rasmus Elsoe
IntroductionDespite the high number of studies evaluating the outcomes following tibial shaft fractures, the literature lacks studies including objective assessment of patients’ recovery regarding gait pattern. The purpose of the present study was to evaluate whether gait patterns at 6 and 12 months post-operatively following intramedullary nailing of a tibial shaft fracture are different compared with a healthy reference population.Patients and methodsThe study design was a prospective cohort study. The primary outcome measurement was the gait patterns at 6 and 12 months post-operatively measured with a 6-meter-long pressure-sensitive mat. The mat registers footprints and present gait speed, cadence as well as temporal and spatial parameters of the gait cycle. Gait patterns were compared to a healthy reference population.Results49 patients were included with a mean age of 43.1 years (18 to 79 years). Forty-three patients completed the 12-month follow-up (88%). Gait speed and cadence were significantly increased between the 6- and 12-month follow-up (P<0.001). At 6-month follow-up, patients showed considerable asymmetry in the injured leg compared with the non-injured leg: single-support time 12.8% shorter, swing-time 12.8% longer, step-length 11.9% shorter, and rotation of the foot increased by 32.3%. At the 12-month follow-up, gait asymmetry become almost normalized compared to a healthy reference group.ConclusionIn patients treated by intramedullary nailing following a tibial shaft fracture, gait asymmetry accompanied with slower speed and cadence are common during the first 6 months and become normalized compared with a healthy reference population between 6 and 12 months post-operatively.
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Factors Affecting Early Services for Children Who Are Hard of Hearing.
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Related Articles |
Factors Affecting Early Services for Children Who Are Hard of Hearing.
Lang Speech Hear Serv Sch. 2016 Jan;47(1):16-30
Authors: Harrison M, Page TA, Oleson J, Spratford M, Unflat Berry L, Peterson B, Welhaven A, Arenas RM, Moeller MP
Abstract
PURPOSE: To describe factors affecting early intervention (EI) for children who are hard of hearing, we analyzed (a) service setting(s) and the relationship of setting to families' frequency of participation, and (b) provider preparation, caseload composition, and experience in relation to comfort with skills that support spoken language for children who are deaf and hard of hearing (CDHH).
METHOD: Participants included 122 EI professionals who completed an online questionnaire annually and 131 parents who participated in annual telephone interviews.
RESULTS: Most families received EI in the home. Family participation in this setting was significantly higher than in services provided elsewhere. EI professionals were primarily teachers of CDHH or speech-language pathologists. Caseload composition was correlated moderately to strongly with most provider comfort levels. Level of preparation to support spoken language weakly to moderately correlated with provider comfort with 18 specific skills.
CONCLUSIONS: Results suggest family involvement is highest when EI is home-based, which supports the need for EI in the home whenever possible. Access to hands-on experience with this population, reflected in a high percentage of CDHH on providers' current caseloads, contributed to professional comfort. Specialized preparation made a modest contribution to comfort level.
PMID: 26440475 [PubMed - indexed for MEDLINE]
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Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
Mamm Genome. 2016 Sep 26;
Authors: Sabrautzki S, Sandholzer MA, Lorenz-Depiereux B, Brommage R, Przemeck G, Vargas Panesso IL, Vernaleken A, Garrett L, Baron K, Yildirim AO, Rozman J, Rathkolb B, Gau C, Hans W, Hoelter SM, Marschall S, Stoeger C, Becker L, Fuchs H, Gailus-Durner V, Klingenspor M, Klopstock T, Lengger C, Stefanie L, Wolf E, Strom TM, Wurst W, de Angelis MH
Abstract
Animal models resembling human mutations are valuable tools to research the features of complex human craniofacial syndromes. This is the first report on a viable dominant mouse model carrying a non-synonymous sequence variation within the endothelin receptor type A gene (Ednra c.386A>T, p.Tyr129Phe) derived by an ENU mutagenesis program. The identical amino acid substitution was reported recently as disease causing in three individuals with the mandibulofacial dysostosis with alopecia (MFDA, OMIM 616367) syndrome. We performed standardized phenotyping of wild-type, heterozygous, and homozygous Ednra (Y129F) mice within the German Mouse Clinic. Mutant mice mimic the craniofacial phenotypes of jaw dysplasia, micrognathia, dysplastic temporomandibular joints, auricular dysmorphism, and missing of the squamosal zygomatic process as described for MFDA-affected individuals. As observed in MFDA-affected individuals, mutant Ednra (Y129F) mice exhibit hearing impairment in line with strong abnormalities of the ossicles and further, reduction of some lung volumetric parameters. In general, heterozygous and homozygous mice demonstrated inter-individual diversity of expression of the craniofacial phenotypes as observed in MFDA patients but without showing any cleft palates, eyelid defects, or alopecia. Mutant Ednra (Y129F) mice represent a valuable viable model for complex human syndromes of the first and second pharyngeal arches and for further studies and analysis of impaired endothelin 1 (EDN1)-endothelin receptor type A (EDNRA) signaling. Above all, Ednra (Y129F) mice model the recently published human MFDA syndrome and may be helpful for further disease understanding and development of therapeutic interventions.
PMID: 27671791 [PubMed - as supplied by publisher]
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Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
Viable Ednra (Y129F) mice feature human mandibulofacial dysostosis with alopecia (MFDA) syndrome due to the homologue mutation.
Mamm Genome. 2016 Sep 26;
Authors: Sabrautzki S, Sandholzer MA, Lorenz-Depiereux B, Brommage R, Przemeck G, Vargas Panesso IL, Vernaleken A, Garrett L, Baron K, Yildirim AO, Rozman J, Rathkolb B, Gau C, Hans W, Hoelter SM, Marschall S, Stoeger C, Becker L, Fuchs H, Gailus-Durner V, Klingenspor M, Klopstock T, Lengger C, Stefanie L, Wolf E, Strom TM, Wurst W, de Angelis MH
Abstract
Animal models resembling human mutations are valuable tools to research the features of complex human craniofacial syndromes. This is the first report on a viable dominant mouse model carrying a non-synonymous sequence variation within the endothelin receptor type A gene (Ednra c.386A>T, p.Tyr129Phe) derived by an ENU mutagenesis program. The identical amino acid substitution was reported recently as disease causing in three individuals with the mandibulofacial dysostosis with alopecia (MFDA, OMIM 616367) syndrome. We performed standardized phenotyping of wild-type, heterozygous, and homozygous Ednra (Y129F) mice within the German Mouse Clinic. Mutant mice mimic the craniofacial phenotypes of jaw dysplasia, micrognathia, dysplastic temporomandibular joints, auricular dysmorphism, and missing of the squamosal zygomatic process as described for MFDA-affected individuals. As observed in MFDA-affected individuals, mutant Ednra (Y129F) mice exhibit hearing impairment in line with strong abnormalities of the ossicles and further, reduction of some lung volumetric parameters. In general, heterozygous and homozygous mice demonstrated inter-individual diversity of expression of the craniofacial phenotypes as observed in MFDA patients but without showing any cleft palates, eyelid defects, or alopecia. Mutant Ednra (Y129F) mice represent a valuable viable model for complex human syndromes of the first and second pharyngeal arches and for further studies and analysis of impaired endothelin 1 (EDN1)-endothelin receptor type A (EDNRA) signaling. Above all, Ednra (Y129F) mice model the recently published human MFDA syndrome and may be helpful for further disease understanding and development of therapeutic interventions.
PMID: 27671791 [PubMed - as supplied by publisher]
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