Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480
Δευτέρα 12 Σεπτεμβρίου 2016
Functional Foods : Did you know that certain foods or food components may provide health and wellness benefits? These foods, also known as “functional foods,” are thought to provide benefits beyond basic nutrition and may play a role in reducing or minimizing the risk of certain diseases and other health conditions. Examples of these foods include fruits and vegetables, whole grains, fortified foods and beverages and some dietary supplements. Functional characteristics of many traditional foods are being discovered and studied, while new food products are being developed to include beneficial components. By knowing which foods can provide specific health benefits,you can make food and beverage choices that allow you to take greater control of your health. http://www.foodinsight.org/Content/3842/Final%20Functional%20Foods%20Backgrounder.pdf
Lidcombe Program Webcam Treatment for Early Stuttering: A Randomized Controlled Trial
Purpose
Webcam treatment is potentially useful for health care in cases of early stuttering in which clients are isolated from specialized treatment services for geographic and other reasons. The purpose of the present trial was to compare outcomes of clinic and webcam deliveries of the Lidcombe Program treatment (Packman et al., 2015) for early stuttering.
Method
The design was a parallel, open plan, noninferiority randomized controlled trial of the standard Lidcombe Program treatment and the experimental webcam Lidcombe Program treatment. Participants were 49 children aged 3 years 0 months to 5 years 11 months at the start of treatment. Primary outcomes were the percentage of syllables stuttered at 9 months postrandomization and the number of consultations to complete Stage 1 of the Lidcombe Program.
Results
There was insufficient evidence of a posttreatment difference of the percentage of syllables stuttered between the standard and webcam Lidcombe Program treatments. There was insufficient evidence of a difference between the groups for typical stuttering severity measured by parents or the reported clinical relationship with the treating speech-language pathologist.
Conclusions
This trial confirmed the viability of the webcam Lidcombe Program intervention. It appears to be as efficacious and economically viable as the standard, clinic Lidcombe Program treatment.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cIrGFd
via IFTTT
The Relationship Between Speech Production and Speech Perception Deficits in Parkinson's Disease
Purpose
This study investigated the possible relationship between hypokinetic speech production and speech intensity perception in patients with Parkinson's disease (PD).
Method
Participants included 14 patients with idiopathic PD and 14 matched healthy controls (HCs) with normal hearing and cognition. First, speech production was objectified through a standardized speech intelligibility assessment, acoustic analysis, and speech intensity measurements. Second, an overall estimation task and an intensity estimation task were addressed to evaluate overall speech perception and speech intensity perception, respectively. Finally, correlation analysis was performed between the speech characteristics of the overall estimation task and the corresponding acoustic analysis. The interaction between speech production and speech intensity perception was investigated by an intensity imitation task.
Results
Acoustic analysis and speech intensity measurements demonstrated significant differences in speech production between patients with PD and the HCs. A different pattern in the auditory perception of speech and speech intensity was found in the PD group.
Conclusions
Auditory perceptual deficits may influence speech production in patients with PD. The present results suggest a disturbed auditory perception related to an automatic monitoring deficit in PD.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cIrmqb
via IFTTT
Objective Measure of Nasal Air Emission Using Nasal Accelerometry
Purpose
This article describes the development and initial validation of an objective measure of nasal air emission (NAE) using nasal accelerometry.
Method
Nasal acceleration and nasal airflow signals were simultaneously recorded while an expert speech language pathologist modeled NAEs at a variety of severity levels. In addition, microphone and nasal accelerometer signals were collected during the production of /pɑpɑpɑpɑ/ speech utterances by 25 children with and without cleft palate. Fourteen inexperienced raters listened to the microphone signals from the pediatric speakers and rated the samples for the severity of NAE using direct magnitude estimation. Mean listener ratings were compared to a novel quantitative measurement of NAE derived from the nasal acceleration signals.
Results
Correlation between the nasal acceleration energy measure and the measured nasal airflow was high (r = .87). Correlation between the measure and auditory-perceptual ratings was moderate (r = .49).
Conclusion
The measure presented here is quantitative and noninvasive, and the required hardware is inexpensive ($150). Future studies will include speakers with a wider range of NAE severity and etiology, including cleft palate, hearing impairment, or dysarthria. Further development will also involve validation of the measure against airflow measures across subjects.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2czGl8n
via IFTTT
A Brief Version of the Unhelpful Thoughts and Beliefs About Stuttering Scales: The UTBAS-6
Purpose
A significant proportion of adults who stutter experience anxiety in social and speaking situations. The Unhelpful Thoughts and Beliefs About Stuttering (UTBAS) scales provide a comprehensive measure of the unhelpful cognitions associated with social anxiety in stuttering. However, reducing the number of UTBAS items would make it ideal as a brief screening instrument. Therefore, the aim of the present study was to develop a brief version of the full UTBAS scales.
Method
The 66-item UTBAS scales were completed by 337 adults who stutter. Item reduction was used to determine a smaller set of items that could adequately reproduce the total score for each full UTBAS scale.
Results
Item reduction resulted in the inclusion of six items for the brief UTBAS-6 scales. Decile ranges for scores on the brief UTBAS-6 provide reliable estimates of the full UTBAS scores and valuable clinical information about whether a psychological assessment is warranted.
Conclusions
The brief UTBAS-6 provides a reliable and efficient means of screening the unhelpful thoughts and beliefs associated with speech-related anxiety among adults who stutter. Referral for a psychological assessment is recommended in cases where the UTBAS total score falls in or above the fifth decile.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cIqEsZ
via IFTTT
Clinical Characteristics of Voice, Speech, and Swallowing Disorders in Oromandibular Dystonia
Purpose
To better define the clinical characteristics of idiopathic oromandibular dystonia, we studied voice, speech, and swallowing disorders and their impact on activities of daily living.
Method
Fourteen consecutive patients with idiopathic oromandibular dystonia and 14 matched, healthy control subjects were included in the study.
Results
Dysarthria was the most common disorder and its characteristics varied from one patient to another. However, we frequently observed a hyperkinetic, dysarthric profile characterized by imprecise consonants, a rough voice, changes in intensity, and hypernasality. Dysphagia appeared to be slightly less frequent and less disabling than dysarthria. Most patients had difficulty swallowing solids, and the oral phase was particularly problematic. Dysarthria and dysphagia affected activities of daily living in general and the psychological/emotional domain in particular.
Conclusions
The characteristics of dysarthria in oromandibular dystonia vary significantly from one patient to another due to differences in the set of affected muscles, so each patient should receive a personalized rehabilitation program. Dysarthria was the most prominent symptom, although spasmodic dysphonia was more frequent than expected. Further laboratory-based studies are needed to clarify the mechanisms and consequences of dysphagia in oromandibular dystonia.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2czI2m8
via IFTTT
Lidcombe Program Webcam Treatment for Early Stuttering: A Randomized Controlled Trial
Purpose
Webcam treatment is potentially useful for health care in cases of early stuttering in which clients are isolated from specialized treatment services for geographic and other reasons. The purpose of the present trial was to compare outcomes of clinic and webcam deliveries of the Lidcombe Program treatment (Packman et al., 2015) for early stuttering.
Method
The design was a parallel, open plan, noninferiority randomized controlled trial of the standard Lidcombe Program treatment and the experimental webcam Lidcombe Program treatment. Participants were 49 children aged 3 years 0 months to 5 years 11 months at the start of treatment. Primary outcomes were the percentage of syllables stuttered at 9 months postrandomization and the number of consultations to complete Stage 1 of the Lidcombe Program.
Results
There was insufficient evidence of a posttreatment difference of the percentage of syllables stuttered between the standard and webcam Lidcombe Program treatments. There was insufficient evidence of a difference between the groups for typical stuttering severity measured by parents or the reported clinical relationship with the treating speech-language pathologist.
Conclusions
This trial confirmed the viability of the webcam Lidcombe Program intervention. It appears to be as efficacious and economically viable as the standard, clinic Lidcombe Program treatment.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIrGFd
via IFTTT
The Relationship Between Speech Production and Speech Perception Deficits in Parkinson's Disease
Purpose
This study investigated the possible relationship between hypokinetic speech production and speech intensity perception in patients with Parkinson's disease (PD).
Method
Participants included 14 patients with idiopathic PD and 14 matched healthy controls (HCs) with normal hearing and cognition. First, speech production was objectified through a standardized speech intelligibility assessment, acoustic analysis, and speech intensity measurements. Second, an overall estimation task and an intensity estimation task were addressed to evaluate overall speech perception and speech intensity perception, respectively. Finally, correlation analysis was performed between the speech characteristics of the overall estimation task and the corresponding acoustic analysis. The interaction between speech production and speech intensity perception was investigated by an intensity imitation task.
Results
Acoustic analysis and speech intensity measurements demonstrated significant differences in speech production between patients with PD and the HCs. A different pattern in the auditory perception of speech and speech intensity was found in the PD group.
Conclusions
Auditory perceptual deficits may influence speech production in patients with PD. The present results suggest a disturbed auditory perception related to an automatic monitoring deficit in PD.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIrmqb
via IFTTT
Objective Measure of Nasal Air Emission Using Nasal Accelerometry
Purpose
This article describes the development and initial validation of an objective measure of nasal air emission (NAE) using nasal accelerometry.
Method
Nasal acceleration and nasal airflow signals were simultaneously recorded while an expert speech language pathologist modeled NAEs at a variety of severity levels. In addition, microphone and nasal accelerometer signals were collected during the production of /pɑpɑpɑpɑ/ speech utterances by 25 children with and without cleft palate. Fourteen inexperienced raters listened to the microphone signals from the pediatric speakers and rated the samples for the severity of NAE using direct magnitude estimation. Mean listener ratings were compared to a novel quantitative measurement of NAE derived from the nasal acceleration signals.
Results
Correlation between the nasal acceleration energy measure and the measured nasal airflow was high (r = .87). Correlation between the measure and auditory-perceptual ratings was moderate (r = .49).
Conclusion
The measure presented here is quantitative and noninvasive, and the required hardware is inexpensive ($150). Future studies will include speakers with a wider range of NAE severity and etiology, including cleft palate, hearing impairment, or dysarthria. Further development will also involve validation of the measure against airflow measures across subjects.from #Audiology via ola Kala on Inoreader http://ift.tt/2czGl8n
via IFTTT
A Brief Version of the Unhelpful Thoughts and Beliefs About Stuttering Scales: The UTBAS-6
Purpose
A significant proportion of adults who stutter experience anxiety in social and speaking situations. The Unhelpful Thoughts and Beliefs About Stuttering (UTBAS) scales provide a comprehensive measure of the unhelpful cognitions associated with social anxiety in stuttering. However, reducing the number of UTBAS items would make it ideal as a brief screening instrument. Therefore, the aim of the present study was to develop a brief version of the full UTBAS scales.
Method
The 66-item UTBAS scales were completed by 337 adults who stutter. Item reduction was used to determine a smaller set of items that could adequately reproduce the total score for each full UTBAS scale.
Results
Item reduction resulted in the inclusion of six items for the brief UTBAS-6 scales. Decile ranges for scores on the brief UTBAS-6 provide reliable estimates of the full UTBAS scores and valuable clinical information about whether a psychological assessment is warranted.
Conclusions
The brief UTBAS-6 provides a reliable and efficient means of screening the unhelpful thoughts and beliefs associated with speech-related anxiety among adults who stutter. Referral for a psychological assessment is recommended in cases where the UTBAS total score falls in or above the fifth decile.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIqEsZ
via IFTTT
Clinical Characteristics of Voice, Speech, and Swallowing Disorders in Oromandibular Dystonia
Purpose
To better define the clinical characteristics of idiopathic oromandibular dystonia, we studied voice, speech, and swallowing disorders and their impact on activities of daily living.
Method
Fourteen consecutive patients with idiopathic oromandibular dystonia and 14 matched, healthy control subjects were included in the study.
Results
Dysarthria was the most common disorder and its characteristics varied from one patient to another. However, we frequently observed a hyperkinetic, dysarthric profile characterized by imprecise consonants, a rough voice, changes in intensity, and hypernasality. Dysphagia appeared to be slightly less frequent and less disabling than dysarthria. Most patients had difficulty swallowing solids, and the oral phase was particularly problematic. Dysarthria and dysphagia affected activities of daily living in general and the psychological/emotional domain in particular.
Conclusions
The characteristics of dysarthria in oromandibular dystonia vary significantly from one patient to another due to differences in the set of affected muscles, so each patient should receive a personalized rehabilitation program. Dysarthria was the most prominent symptom, although spasmodic dysphonia was more frequent than expected. Further laboratory-based studies are needed to clarify the mechanisms and consequences of dysphagia in oromandibular dystonia.from #Audiology via ola Kala on Inoreader http://ift.tt/2czI2m8
via IFTTT
Lidcombe Program Webcam Treatment for Early Stuttering: A Randomized Controlled Trial
Purpose
Webcam treatment is potentially useful for health care in cases of early stuttering in which clients are isolated from specialized treatment services for geographic and other reasons. The purpose of the present trial was to compare outcomes of clinic and webcam deliveries of the Lidcombe Program treatment (Packman et al., 2015) for early stuttering.
Method
The design was a parallel, open plan, noninferiority randomized controlled trial of the standard Lidcombe Program treatment and the experimental webcam Lidcombe Program treatment. Participants were 49 children aged 3 years 0 months to 5 years 11 months at the start of treatment. Primary outcomes were the percentage of syllables stuttered at 9 months postrandomization and the number of consultations to complete Stage 1 of the Lidcombe Program.
Results
There was insufficient evidence of a posttreatment difference of the percentage of syllables stuttered between the standard and webcam Lidcombe Program treatments. There was insufficient evidence of a difference between the groups for typical stuttering severity measured by parents or the reported clinical relationship with the treating speech-language pathologist.
Conclusions
This trial confirmed the viability of the webcam Lidcombe Program intervention. It appears to be as efficacious and economically viable as the standard, clinic Lidcombe Program treatment.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIrGFd
via IFTTT
The Relationship Between Speech Production and Speech Perception Deficits in Parkinson's Disease
Purpose
This study investigated the possible relationship between hypokinetic speech production and speech intensity perception in patients with Parkinson's disease (PD).
Method
Participants included 14 patients with idiopathic PD and 14 matched healthy controls (HCs) with normal hearing and cognition. First, speech production was objectified through a standardized speech intelligibility assessment, acoustic analysis, and speech intensity measurements. Second, an overall estimation task and an intensity estimation task were addressed to evaluate overall speech perception and speech intensity perception, respectively. Finally, correlation analysis was performed between the speech characteristics of the overall estimation task and the corresponding acoustic analysis. The interaction between speech production and speech intensity perception was investigated by an intensity imitation task.
Results
Acoustic analysis and speech intensity measurements demonstrated significant differences in speech production between patients with PD and the HCs. A different pattern in the auditory perception of speech and speech intensity was found in the PD group.
Conclusions
Auditory perceptual deficits may influence speech production in patients with PD. The present results suggest a disturbed auditory perception related to an automatic monitoring deficit in PD.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIrmqb
via IFTTT
Objective Measure of Nasal Air Emission Using Nasal Accelerometry
Purpose
This article describes the development and initial validation of an objective measure of nasal air emission (NAE) using nasal accelerometry.
Method
Nasal acceleration and nasal airflow signals were simultaneously recorded while an expert speech language pathologist modeled NAEs at a variety of severity levels. In addition, microphone and nasal accelerometer signals were collected during the production of /pɑpɑpɑpɑ/ speech utterances by 25 children with and without cleft palate. Fourteen inexperienced raters listened to the microphone signals from the pediatric speakers and rated the samples for the severity of NAE using direct magnitude estimation. Mean listener ratings were compared to a novel quantitative measurement of NAE derived from the nasal acceleration signals.
Results
Correlation between the nasal acceleration energy measure and the measured nasal airflow was high (r = .87). Correlation between the measure and auditory-perceptual ratings was moderate (r = .49).
Conclusion
The measure presented here is quantitative and noninvasive, and the required hardware is inexpensive ($150). Future studies will include speakers with a wider range of NAE severity and etiology, including cleft palate, hearing impairment, or dysarthria. Further development will also involve validation of the measure against airflow measures across subjects.from #Audiology via ola Kala on Inoreader http://ift.tt/2czGl8n
via IFTTT
A Brief Version of the Unhelpful Thoughts and Beliefs About Stuttering Scales: The UTBAS-6
Purpose
A significant proportion of adults who stutter experience anxiety in social and speaking situations. The Unhelpful Thoughts and Beliefs About Stuttering (UTBAS) scales provide a comprehensive measure of the unhelpful cognitions associated with social anxiety in stuttering. However, reducing the number of UTBAS items would make it ideal as a brief screening instrument. Therefore, the aim of the present study was to develop a brief version of the full UTBAS scales.
Method
The 66-item UTBAS scales were completed by 337 adults who stutter. Item reduction was used to determine a smaller set of items that could adequately reproduce the total score for each full UTBAS scale.
Results
Item reduction resulted in the inclusion of six items for the brief UTBAS-6 scales. Decile ranges for scores on the brief UTBAS-6 provide reliable estimates of the full UTBAS scores and valuable clinical information about whether a psychological assessment is warranted.
Conclusions
The brief UTBAS-6 provides a reliable and efficient means of screening the unhelpful thoughts and beliefs associated with speech-related anxiety among adults who stutter. Referral for a psychological assessment is recommended in cases where the UTBAS total score falls in or above the fifth decile.from #Audiology via ola Kala on Inoreader http://ift.tt/2cIqEsZ
via IFTTT
Clinical Characteristics of Voice, Speech, and Swallowing Disorders in Oromandibular Dystonia
Purpose
To better define the clinical characteristics of idiopathic oromandibular dystonia, we studied voice, speech, and swallowing disorders and their impact on activities of daily living.
Method
Fourteen consecutive patients with idiopathic oromandibular dystonia and 14 matched, healthy control subjects were included in the study.
Results
Dysarthria was the most common disorder and its characteristics varied from one patient to another. However, we frequently observed a hyperkinetic, dysarthric profile characterized by imprecise consonants, a rough voice, changes in intensity, and hypernasality. Dysphagia appeared to be slightly less frequent and less disabling than dysarthria. Most patients had difficulty swallowing solids, and the oral phase was particularly problematic. Dysarthria and dysphagia affected activities of daily living in general and the psychological/emotional domain in particular.
Conclusions
The characteristics of dysarthria in oromandibular dystonia vary significantly from one patient to another due to differences in the set of affected muscles, so each patient should receive a personalized rehabilitation program. Dysarthria was the most prominent symptom, although spasmodic dysphonia was more frequent than expected. Further laboratory-based studies are needed to clarify the mechanisms and consequences of dysphagia in oromandibular dystonia.from #Audiology via ola Kala on Inoreader http://ift.tt/2czI2m8
via IFTTT
Evaluación funcional de la etapa faríngea de la deglución utilizando sonar Doppler. Revisión crítica de la literatura
Source:Revista de Logopedia, Foniatría y Audiología
Author(s): Rodrigo Maximiliano Jerez
El sonar Doppler es una herramienta que permite captar lo que sucede durante la etapa faríngea de la deglución, siendo el sonido percibido y observado un reflejo parcial de la actividad motora que se desencadena. El presente trabajo indaga acerca de las posibilidades del sonar Doppler y su aplicación en la evaluación funcional de la deglución. Se desarrolla un diseño de investigación observacional y retrospectivo, bajo la metodología de revisión sistemática a partir de material bibliográfico, investigaciones y publicaciones de artículos de revistas en inglés, portugués y español, consultando las bases de datos PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, además de revistas especializadas en ASHA, MedLine, CEFAC y Redalyc. Aunque la fiabilidad y validez en el uso del sonar Doppler para la evaluación funcional de la etapa faríngea de la deglución no están aseguradas, podría llegar a brindar enorme ayuda en el diagnóstico de las aspiraciones y/o penetraciones durante el proceso deglutorio. Se insiste en una constante revisión de la metodología para la detección correcta de los sonidos de la deglución y su posterior análisis e interpretación clínica.Sonar Doppler is a tool that can capture what happens during the pharyngeal stage of swallowing, being the sound perceived and the noting a partial reflection of the motor activity that is triggered. This paper focuses on the possibilities of sonar Doppler and its application in functional assessment of swallowing. The design of this research is retrospective and observational, developed under the systematic review methodology, from bibliographical material, pieces of research and publications of journal articles in English, Portuguese and Spanish, taking the databases of PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, besides specialized magazines in ASHA, MedLine, CEFAC and Redalyc. Although the reliability and validity in the use of sonar Doppler for the functional evaluation of the pharyngeal stage of swallowing are uncertain, it could provide enormous help in diagnosing aspirations and/or penetrations during the swallowing process. We insist on a constant review of the methodology for the correct detection of sounds of swallowing and subsequent analysis and clinical interpretation.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2czka26
via IFTTT
Evaluación funcional de la etapa faríngea de la deglución utilizando sonar Doppler. Revisión crítica de la literatura
Source:Revista de Logopedia, Foniatría y Audiología
Author(s): Rodrigo Maximiliano Jerez
El sonar Doppler es una herramienta que permite captar lo que sucede durante la etapa faríngea de la deglución, siendo el sonido percibido y observado un reflejo parcial de la actividad motora que se desencadena. El presente trabajo indaga acerca de las posibilidades del sonar Doppler y su aplicación en la evaluación funcional de la deglución. Se desarrolla un diseño de investigación observacional y retrospectivo, bajo la metodología de revisión sistemática a partir de material bibliográfico, investigaciones y publicaciones de artículos de revistas en inglés, portugués y español, consultando las bases de datos PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, además de revistas especializadas en ASHA, MedLine, CEFAC y Redalyc. Aunque la fiabilidad y validez en el uso del sonar Doppler para la evaluación funcional de la etapa faríngea de la deglución no están aseguradas, podría llegar a brindar enorme ayuda en el diagnóstico de las aspiraciones y/o penetraciones durante el proceso deglutorio. Se insiste en una constante revisión de la metodología para la detección correcta de los sonidos de la deglución y su posterior análisis e interpretación clínica.Sonar Doppler is a tool that can capture what happens during the pharyngeal stage of swallowing, being the sound perceived and the noting a partial reflection of the motor activity that is triggered. This paper focuses on the possibilities of sonar Doppler and its application in functional assessment of swallowing. The design of this research is retrospective and observational, developed under the systematic review methodology, from bibliographical material, pieces of research and publications of journal articles in English, Portuguese and Spanish, taking the databases of PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, besides specialized magazines in ASHA, MedLine, CEFAC and Redalyc. Although the reliability and validity in the use of sonar Doppler for the functional evaluation of the pharyngeal stage of swallowing are uncertain, it could provide enormous help in diagnosing aspirations and/or penetrations during the swallowing process. We insist on a constant review of the methodology for the correct detection of sounds of swallowing and subsequent analysis and clinical interpretation.
from #Audiology via ola Kala on Inoreader http://ift.tt/2czka26
via IFTTT
Evaluación funcional de la etapa faríngea de la deglución utilizando sonar Doppler. Revisión crítica de la literatura
Source:Revista de Logopedia, Foniatría y Audiología
Author(s): Rodrigo Maximiliano Jerez
El sonar Doppler es una herramienta que permite captar lo que sucede durante la etapa faríngea de la deglución, siendo el sonido percibido y observado un reflejo parcial de la actividad motora que se desencadena. El presente trabajo indaga acerca de las posibilidades del sonar Doppler y su aplicación en la evaluación funcional de la deglución. Se desarrolla un diseño de investigación observacional y retrospectivo, bajo la metodología de revisión sistemática a partir de material bibliográfico, investigaciones y publicaciones de artículos de revistas en inglés, portugués y español, consultando las bases de datos PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, además de revistas especializadas en ASHA, MedLine, CEFAC y Redalyc. Aunque la fiabilidad y validez en el uso del sonar Doppler para la evaluación funcional de la etapa faríngea de la deglución no están aseguradas, podría llegar a brindar enorme ayuda en el diagnóstico de las aspiraciones y/o penetraciones durante el proceso deglutorio. Se insiste en una constante revisión de la metodología para la detección correcta de los sonidos de la deglución y su posterior análisis e interpretación clínica.Sonar Doppler is a tool that can capture what happens during the pharyngeal stage of swallowing, being the sound perceived and the noting a partial reflection of the motor activity that is triggered. This paper focuses on the possibilities of sonar Doppler and its application in functional assessment of swallowing. The design of this research is retrospective and observational, developed under the systematic review methodology, from bibliographical material, pieces of research and publications of journal articles in English, Portuguese and Spanish, taking the databases of PubMed, SciELO, EBSCO Host, Scopus, Springer, Cochrane, besides specialized magazines in ASHA, MedLine, CEFAC and Redalyc. Although the reliability and validity in the use of sonar Doppler for the functional evaluation of the pharyngeal stage of swallowing are uncertain, it could provide enormous help in diagnosing aspirations and/or penetrations during the swallowing process. We insist on a constant review of the methodology for the correct detection of sounds of swallowing and subsequent analysis and clinical interpretation.
from #Audiology via ola Kala on Inoreader http://ift.tt/2czka26
via IFTTT
Toward a Differential Diagnosis of Hidden Hearing Loss in Humans
by M. Charles Liberman, Michael J. Epstein, Sandra S. Cleveland, Haobing Wang, Stéphane F. Maison
Recent work suggests that hair cells are not the most vulnerable elements in the inner ear; rather, it is the synapses between hair cells and cochlear nerve terminals that degenerate first in the aging or noise-exposed ear. This primary neural degeneration does not affect hearing thresholds, but likely contributes to problems understanding speech in difficult listening environments, and may be important in the generation of tinnitus and/or hyperacusis. To look for signs of cochlear synaptopathy in humans, we recruited college students and divided them into low-risk and high-risk groups based on self-report of noise exposure and use of hearing protection. Cochlear function was assessed by otoacoustic emissions and click-evoked electrocochleography; hearing was assessed by behavioral audiometry and word recognition with or without noise or time compression and reverberation. Both groups had normal thresholds at standard audiometric frequencies, however, the high-risk group showed significant threshold elevation at high frequencies (10–16 kHz), consistent with early stages of noise damage. Electrocochleography showed a significant difference in the ratio between the waveform peaks generated by hair cells (Summating Potential; SP) vs. cochlear neurons (Action Potential; AP), i.e. the SP/AP ratio, consistent with selective neural loss. The high-risk group also showed significantly poorer performance on word recognition in noise or with time compression and reverberation, and reported heightened reactions to sound consistent with hyperacusis. These results suggest that the SP/AP ratio may be useful in the diagnosis of “hidden hearing loss” and that, as suggested by animal models, the noise-induced loss of cochlear nerve synapses leads to deficits in hearing abilities in difficult listening situations, despite the presence of normal thresholds at standard audiometric frequencies.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cq5Oxj
via IFTTT
Examining the Language Phenotype in Children With Typical Development, Specific Language Impairment, and Fragile X Syndrome
Purpose
One aspect of morphosyntax, finiteness marking, was compared in children with fragile X syndrome (FXS), specific language impairment (SLI), and typical development matched on mean length of utterance (MLU).
Method
Nineteen children with typical development (mean age = 3.3 years), 20 children with SLI (mean age = 4.9 years), and 17 boys with FXS (mean age = 11.9 years) completed the Test of Early Grammatical Impairment (TEGI; Rice & Wexler, 2001), and other cognitive and language assessments. Quantitative comparisons on finiteness marking and qualitative comparisons of unscorable (i.e., nontarget) TEGI responses were conducted.
Results
Children with typical development and FXS performed better on finiteness marking than children with SLI. Although unscorable responses were infrequent, boys with FXS produced more unscorable responses than children with typical development and SLI.
Conclusions
Although boys with FXS have language deficits, they performed similarly to MLU-matched typically developing children on finiteness marking. This language profile differs from children with SLI, who present with a delay-within-a-delay profile with finiteness marking delays that exceed delays in MLU. Unscorable responses produced by the boys with FXS may reflect pragmatic deficits, which are prominent in this population. Assessment procedures should be carefully considered when examining language in boys with FXS.from #Audiology via ola Kala on Inoreader http://ift.tt/2cRt5hm
via IFTTT
Examining the Language Phenotype in Children With Typical Development, Specific Language Impairment, and Fragile X Syndrome
Purpose
One aspect of morphosyntax, finiteness marking, was compared in children with fragile X syndrome (FXS), specific language impairment (SLI), and typical development matched on mean length of utterance (MLU).
Method
Nineteen children with typical development (mean age = 3.3 years), 20 children with SLI (mean age = 4.9 years), and 17 boys with FXS (mean age = 11.9 years) completed the Test of Early Grammatical Impairment (TEGI; Rice & Wexler, 2001), and other cognitive and language assessments. Quantitative comparisons on finiteness marking and qualitative comparisons of unscorable (i.e., nontarget) TEGI responses were conducted.
Results
Children with typical development and FXS performed better on finiteness marking than children with SLI. Although unscorable responses were infrequent, boys with FXS produced more unscorable responses than children with typical development and SLI.
Conclusions
Although boys with FXS have language deficits, they performed similarly to MLU-matched typically developing children on finiteness marking. This language profile differs from children with SLI, who present with a delay-within-a-delay profile with finiteness marking delays that exceed delays in MLU. Unscorable responses produced by the boys with FXS may reflect pragmatic deficits, which are prominent in this population. Assessment procedures should be carefully considered when examining language in boys with FXS.from #Audiology via ola Kala on Inoreader http://ift.tt/2cRt5hm
via IFTTT
Examining the Language Phenotype in Children With Typical Development, Specific Language Impairment, and Fragile X Syndrome
Purpose
One aspect of morphosyntax, finiteness marking, was compared in children with fragile X syndrome (FXS), specific language impairment (SLI), and typical development matched on mean length of utterance (MLU).
Method
Nineteen children with typical development (mean age = 3.3 years), 20 children with SLI (mean age = 4.9 years), and 17 boys with FXS (mean age = 11.9 years) completed the Test of Early Grammatical Impairment (TEGI; Rice & Wexler, 2001), and other cognitive and language assessments. Quantitative comparisons on finiteness marking and qualitative comparisons of unscorable (i.e., nontarget) TEGI responses were conducted.
Results
Children with typical development and FXS performed better on finiteness marking than children with SLI. Although unscorable responses were infrequent, boys with FXS produced more unscorable responses than children with typical development and SLI.
Conclusions
Although boys with FXS have language deficits, they performed similarly to MLU-matched typically developing children on finiteness marking. This language profile differs from children with SLI, who present with a delay-within-a-delay profile with finiteness marking delays that exceed delays in MLU. Unscorable responses produced by the boys with FXS may reflect pragmatic deficits, which are prominent in this population. Assessment procedures should be carefully considered when examining language in boys with FXS.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cRt5hm
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10 New Marketing Ideas—Don’t Give Up
Marketing can be a very frustrating aspect of business especially given the increasing number of mediums in which to place your message. Traditional forms of marketing, such as direct mail and print ads, are costing more and producing less and tackling online and social media advertising can be overwhelming for those unfamiliar with it. However, we can’t give up because marketing is essential in the quest for new patients.
Review these 10 new ideas that may provide some new insights into marketing.
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Investigation of horizontal refraction on Florida Straits continental shelf using a three-dimensional Gaussian ray bundling model
Acoustic transmission loss measurements from the calibration operations (CALOPS) experiment for the Shallow Water Array Performance (SWAP) program included horizontally refracted returns that were as much as 30° away from the true bearing between source and receiver. In many cases, the in-shore refracted path was 20 dB stronger than the true bearing path. In this study CALOPS transmission loss measurements at 415 Hz are compared to predictions from a three-dimensional Gaussian ray bundling model. The geoacoustic model that provides good model-data comparison is consistent with the geologic and sediment core data collected at the location but differs slightly from the bottom model used at lower frequencies (206 and 52.5 Hz) in a previous study.
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Sparse spatial spectral estimation in directional noise environment
White Gaussian noise assumption is widely used in the field of spatial spectral estimation. But, the practical ambient noise usually does not satisfy this assumption, which may seriously affect the performance of direction of arrival estimation. This letter presents a linear noise model that can provide a more complete description of the practical ambient noise field, and then proposes a directional noise field sparse spectrum fitting (DN-SpSF) algorithm to estimate the spatial spectral in a directional noise field. Simulations and experimental results demonstrate the good performance of the DN-SpSF algorithm in a spatially directional noise environment.
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Effects of Load Carriage and Footwear on Lower Extremity Kinetics and Kinematics During Overground Walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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In-vivo Quantification of Dynamic Hip Joint Center Errors and Soft Tissue Artifact
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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In shoe pressure measurements during different motor tasks while wearing safety shoes: the effect of custom made insoles vs. prefabricated and off-the-shelf
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Examination of stride-to-stride independence of selected lower extremity kinematic and temporal variables during treadmill walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Effects of Load Carriage and Footwear on Lower Extremity Kinetics and Kinematics During Overground Walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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In-vivo Quantification of Dynamic Hip Joint Center Errors and Soft Tissue Artifact
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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In shoe pressure measurements during different motor tasks while wearing safety shoes: the effect of custom made insoles vs. prefabricated and off-the-shelf
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Examination of stride-to-stride independence of selected lower extremity kinematic and temporal variables during treadmill walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Effects of Load Carriage and Footwear on Lower Extremity Kinetics and Kinematics During Overground Walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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Source:Gait & Posture
Author(s): Kevin D. Dames, Jeremy D. Smith
Kinetic and kinematic responses during walking vary by footwear condition. Load carriage also influences gait patterns, but it is unclear how an external load influences barefoot walking. Twelve healthy adults (5 women, 7 men) with no known gait abnormalities participated in this study (age=23±3years, height=1.73±0.11m, and mass=70.90±12.67kg). Ground reaction forces and 3D motion were simultaneously collected during overground walking at 1.5ms−1 in four conditions: Barefoot Unloaded, Shod Unloaded, Barefoot Loaded, and Shod Loaded. Barefoot walking reduced knee and hip joint ranges of motion, as well as stride length, stance time, swing time, and double support time. Load carriage increased stance and double support times. The 15% body weight load increased GRFs ∼15%. Walking barefoot reduced peak anteroposterior GRFs but not peak vertical GRFs. Load carriage increased hip, knee, and ankle joint moments and powers, while walking barefoot increased knee and hip moments and powers. Thus, spatiotemporal and kinematic adjustments to walking barefoot decrease GRFs but increase knee and hip kinetic measures during overground walking. The ankle seems to be less affected by these footwear conditions. Regardless of footwear, loading requires larger GRFs, joint loads, and joint powers.
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In-vivo Quantification of Dynamic Hip Joint Center Errors and Soft Tissue Artifact
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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Source:Gait & Posture
Author(s): Niccolo M. Fiorentino, Penny R. Atkins, Michael J. Kutschke, K. Bo Foreman, Andrew E. Anderson
Hip joint center (HJC) measurement error can adversely affect predictions from biomechanical models. Soft tissue artifact (STA) may exacerbate HJC errors during dynamic motions. We quantified HJC error and the effect of STA in 11 young, asymptomatic adults during six activities. Subjects were imaged simultaneously with reflective skin markers (SM) and dual fluoroscopy (DF), an x-ray based technique with submillimeter accuracy that does not suffer from STA. Five HJCs were defined from locations of SM using three predictive (i.e., based on regression) and two functional methods; these calculations were repeated using the DF solutions. Hip joint center motion was analyzed during six degrees-of-freedom (default) and three degrees-of-freedom hip joint kinematics. The position of the DF-measured femoral head center (FHC), served as the reference to calculate HJC error. The effect of STA was quantified with mean absolute deviation. HJC errors were (mean±SD) 16.6±8.4mm and 11.7±11.0mm using SM and DF solutions, respectively. HJC errors from SM measurements were all significantly different from the FHC in at least one anatomical direction during multiple activities. The mean absolute deviation of SM-based HJCs was 2.8±0.7mm, which was greater than that for the FHC (0.6±0.1mm), suggesting that STA caused approximately 2.2mm of spurious HJC motion. Constraining the hip joint to three degrees-of-freedom led to approximately 3.1mm of spurious HJC motion. Our results indicate that STA-induced motion of the HJC contributes to the overall error, but inaccuracies inherent with predictive and functional methods appear to be a larger source of error.
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In shoe pressure measurements during different motor tasks while wearing safety shoes: the effect of custom made insoles vs. prefabricated and off-the-shelf
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Source:Gait & Posture
Author(s): Paolo Caravaggi, Alessia Giangrande, Giada Lullini, Giuseppe Padula, Lisa Berti, Alberto Leardini
Health and safety regulations in many countries require workers at risk to wear safety shoes in a factory environment. These shoes are often heavy, rigid, and uncomfortable. Wearing safety shoes daily leads to foot problems, discomfort and fatigue, resulting also in the loss of numerous working days. Currently, knowledge of the biomechanical effects of insoles in safety shoes, during working activities, is very limited.Seventeen workers from a metalworking factory were selected and clinically examined for any foot conditions. Workers feet were 3D scanned, with regards to their plantar view, and the images used to design 34 custom-insoles, based on foot and safety shoe models.Three insoles were blind-tested by each worker: custom (CUS); prefabricated with the safety-shoe (PSS), and off-the-shelf (OTS). Foot-to-insole pressure distribution was measured in seven motor tasks replicating typical working activities: single and double-leg standing; weight lifting; stair ascending and descending; normal and fast walking.Wearing CUS within safety shoes resulted in a greater uniform pressure distribution across plantar regions for most of the working activities. Peak pressure at the forefoot during normal walking was the lowest in the custom insole (CUS 275.9±55.3kPa; OTS 332.7±75.5kPa; PSS 304.5±54.2kPa). Normal and fast walking were found to be the most demanding activities in terms of peak pressure.Wearing safety shoes results in high pedobarographic parameters in several foot regions. The use of custom insoles designed on the foot morphology helps decrease peak pressure and pressure-time integral compared to prefabricated featureless insoles.
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Examination of stride-to-stride independence of selected lower extremity kinematic and temporal variables during treadmill walking
Publication date: Available online 11 September 2016
Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Source:Gait & Posture
Author(s): Hyung Suk Yang, Lee T. Atkins, C. Roger James
The purpose of this study was to examine the nature of the intra-subject independence among strides during treadmill walking. We investigated the strength of the relationships among strides sampled in different ways from a population of observed strides. Eighteen asymptomatic subjects walked on a treadmill at 1.4±0.1m/s. Maximum angles and ranges of motion from the ankle, knee and hip joints, as well as stride duration were obtained and autocorrelation coefficients (AC) for 3 lags were calculated among 12 strides sampled consecutively (CS), in order but non-adjacently (NA), and randomly (RA). Ninety-nine percent of AC values were within Bartlett's 95% confidence interval limits and thus the strides were not considered significantly autocorrelated. The results support the hypothesis that strides obtained from an individual walking on a treadmill can be statistically independent. This supports the theoretical assumption that in some circumstances humans can be modeled as random sample generators due to inherent movement variability. The ability to assess statistically clinical intervention provides objective rigor for evaluating rehabilitation outcomes.
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Parental views on otitis media: systematic review of qualitative studies.
Parental views on otitis media: systematic review of qualitative studies.
Eur J Pediatr. 2016 Sep 10;
Authors: Chando S, Young C, Craig JC, Gunasekera H, Tong A
Abstract
This study aims to describe parental experiences and perspectives of caring for a child with otitis media. We conducted a systematic review of qualitative studies on parental perspectives on caring for a child with otitis media. We searched electronic databases to July 2015. Seventeen studies involving 284 participants from six countries were included. We identified seven themes: diminishing competency (guilt over failure to identify symptoms, helpless and despairing, fear of complications, disempowered and dismissed); disrupting life schedules (disturbing sleep, interfering with work, burden on family); social isolation (stigma and judgement, sick consciousness); threatening normal development (delaying growth milestones, impairing interpersonal skills, impeding education); taking ownership (recognising symptoms, diagnostic closure, working the system, protecting against physical trauma, contingency planning); valuing support (needing respite, depending on community, clinician validation); and cherishing health (relief with treatment success, inspiring resilience).
CONCLUSION: The additional medical responsibilities and anxieties of parents caring for a child with otitis media, often discounted by clinicians, can be disempowering and disruptive. Chronicity can raise doubt about treatment efficacy and parental competency, and fears regarding their child's development. Care that fosters parental confidence and addresses their concerns about the child's development may improve treatment outcomes for children with otitis media.
WHAT IS KNOWN: • Otitis media is a leading cause of conductive hearing loss in children. • Parental perception of the treatment burden of otitis media can potentially affect their confidence and ability to care for their child. What is New: • We identified five themes to reflect parental perspectives: diminishing competency, disrupting life schedules, social isolation, threatening normal development, taking ownership, valuing support, and cherishing health. • Parents may perceive caring for a child with otitis media as disempowering and disruptive and with reoccurrence doubt treatment efficacy and their parental competency and develop fears regarding their child's development.
PMID: 27614962 [PubMed - as supplied by publisher]
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Interaction between diabetes mellitus and hypertension on risk of hearing loss in highly endogamous population.
Interaction between diabetes mellitus and hypertension on risk of hearing loss in highly endogamous population.
Diabetes Metab Syndr. 2016 Sep 5;
Authors: Bener A, Al-Hamaq AO, Abdulhadi K, Salahaldin AH, Gansan L
Abstract
AIM: The aim of this study was to determine the prevalence of hearing loss and its association with type 2 diabetes mellitus (T2DM) in a highly endogamous population.
DESIGN: This is a cross-sectional study.
SETTING: The present study is carried out in Ear Nose Throat (ENT) and Endocrinology outpatient clinics of the Hamad General and Rumeilah Hospitals, Hamad Medical Corporation.
SUBJECTS: All subjects aged between 20 and 59 years who visited the Endocrinology and ENT outpatient clinics of the Hamad Medical Corporation with hearing difficulty were included in this study during the period from January 2013 to July 2014.
METHOD: During the study period, prevalence, hearing, audiological test, family history and medical problems associated with hearing impairment in middle aged patients were recorded. Two audiometers Grason Stadler GSI 61 and Madsen Orbiter 922 were used to evaluate the hearing loss.
RESULT: Majority of the hearing loss observed at the age above 45 years old, (44.8% vs 51.7%, p=0.05). The prevalence of hearing impairment was higher in Qataris than in non-Qataris (59.7% vs 46.6%, p<0.001). The consanguineous marriages were observed higher in Hearing loss (32.1%) than in normal hearing (21.8%) (p=0.028). The mean of diabetes onset duration (7.8±4.12years), sleeping disorder (5.81±1.29h), obese subjects (38% vs 27.4%); family history of diabetes (30.6 vs 23.1%) were higher among hearing impairment. The associated risk factors were significantly higher in T2DM with hearing loss, hypoglycemia (32.8% vs 27.4%), retinopathy (313% vs 18.5%), Nephropathy (17.9% vs 9.8%), Neuropathy (17.9% vs 10.2%), macro-vascular disease (11.9% vs 6.2%), diabetic foot ulcer (20.9% vs 12.6%), Tinnitus (68.7% vs 51.3%), and Vertigo (25.4% vs 16.9%) than in normal hearing diabetes. There was a statistically significant differences between hearing impairment and normal hearing among T2DM regarding hearing assessment frequency (p=0.041). There were statistically significant differences between hearing impairment versus normal hearing for vitamin D [18.91±7.65ng/mL vs 22.85±9.00ng/mL; p<0.001], calcium [1.80±0.12ng/mL vs 1.96±0.14mmol/L; p<0.001], magnesium [0.80±0.09mmol/L vs 0.8±0.14mmol/L; p<0.001], phosphorous [1.42±0.30mmol/L vs 1.56±0.26mmol/L; p<0.001], ceatinine [1.42±0.30mmol/L vs 1.56±0.26mmol/L; p<0.001], cholesterol [4.92±1.08mmol/L vs 4.40±1.01mmol/L; p=0.035], LDL [1.92±0.88mmol/L vs 2.09±0.92mmol/L; p=0.024], albumin [43.1±6.10mmol/L vs 39.8±7.93mmol/L; p=0.010], systolic blood pressure [135.8±16.6Hg vs 130.2±12.5Hg; p=0.017] and, diastolic blood pressure [85.1±9.2mmHg vs 83.0±7.9mmHg; p=0.012]. There were highly statistically significant differences between hearing impairment versus normal for both side right and left ear frequency in Db unit (p<0.001). The multivariate stepwise logistic regression analysis revealed that head ache (p<0.001), family history of DM (p<0.001), sleep disturbance (p<0.001), high blood pressure (p=0.006), consanguinity (p=0.010), nationality (p=0.014), age in years (p=0.025), and sheesha smokers (p=0.045) were considered at higher risk as a predictors of hearing loss among diabetic patients.
CONCLUSION: The current study results confirm previous reports that adults with DM and hypertension associated showed greater hearing impairment in highly endogamous population… Diabetic patients with hearing loss were likely to have high blood glucose and other risk factors like hypertension, retinopathy, nephropathy and neuropathy.
PMID: 27614865 [PubMed - as supplied by publisher]
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A comprehensive study of oxidative stress in sudden hearing loss.
A comprehensive study of oxidative stress in sudden hearing loss.
Eur Arch Otorhinolaryngol. 2016 Sep 10;
Authors: Gul F, Muderris T, Yalciner G, Sevil E, Bercin S, Ergin M, Babademez MA, Kiris M
Abstract
Little is known about the association between idiopathic sudden sensorineural hearing loss (ISSNHL) and oxidative stress. We investigated changes in a wide range of oxidants and antioxidants to create a comprehensive picture of oxidative imbalance. In the peripheral blood of 50 ISSNHL patients and 50 healthy subjects, total oxidant status (TOS), total antioxidant status (TAS), paraoxonase (PON), thiol/disulphide levels were measured. Moreover, a global oxidative stress index, reflecting both oxidative and antioxidant counterparts, was also calculated. One-way analysis between oxidative markers and severity of hearing loss were evaluated. The ISSNHL patients showed significantly higher TOS levels than controls (6.02 ± 3.17 vs. 4.5 ± 2.22; p = 0.018). The oxidative index was also significantly higher in patients than controls (0.39 ± 0.19 vs. 0.3 ± 0.14; p = 0.035). TAS, PON, native thiol, and total thiol were not altered. There was no statistical significance between oxidative markers and severity of hearing loss. The binary logistic regression model revealed that disulphide and TOS were associated with ISSNHL. There are alterations in a wide array of oxidants and antioxidants, with balance shifting toward increased oxidative stress in ISSNHL. Our findings may suggest endothelial dysfunction in ISSNHL etiopathogenesis.
PMID: 27614879 [PubMed - as supplied by publisher]
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A comprehensive study of oxidative stress in sudden hearing loss.
A comprehensive study of oxidative stress in sudden hearing loss.
Eur Arch Otorhinolaryngol. 2016 Sep 10;
Authors: Gul F, Muderris T, Yalciner G, Sevil E, Bercin S, Ergin M, Babademez MA, Kiris M
Abstract
Little is known about the association between idiopathic sudden sensorineural hearing loss (ISSNHL) and oxidative stress. We investigated changes in a wide range of oxidants and antioxidants to create a comprehensive picture of oxidative imbalance. In the peripheral blood of 50 ISSNHL patients and 50 healthy subjects, total oxidant status (TOS), total antioxidant status (TAS), paraoxonase (PON), thiol/disulphide levels were measured. Moreover, a global oxidative stress index, reflecting both oxidative and antioxidant counterparts, was also calculated. One-way analysis between oxidative markers and severity of hearing loss were evaluated. The ISSNHL patients showed significantly higher TOS levels than controls (6.02 ± 3.17 vs. 4.5 ± 2.22; p = 0.018). The oxidative index was also significantly higher in patients than controls (0.39 ± 0.19 vs. 0.3 ± 0.14; p = 0.035). TAS, PON, native thiol, and total thiol were not altered. There was no statistical significance between oxidative markers and severity of hearing loss. The binary logistic regression model revealed that disulphide and TOS were associated with ISSNHL. There are alterations in a wide array of oxidants and antioxidants, with balance shifting toward increased oxidative stress in ISSNHL. Our findings may suggest endothelial dysfunction in ISSNHL etiopathogenesis.
PMID: 27614879 [PubMed - as supplied by publisher]
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20Q: Frequency Lowering Ten Years Later - New Technology Innovations
Since all the initial hoopla, I really haven’t paid too much attention to frequency lowering in hearing aids. Has much really changed? Most certainly. You might recall that back in the 1990s, AVR Sonovation had a frequency-lowering analog device, but the modern products we know today were not introduced until ten years ago. 
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