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Τρίτη 16 Οκτωβρίου 2018
Spatial Noise Processing in Hearing Aids Modulates Neural Markers Linked to Listening Effort: An EEG Study
The objective of the course is to learn about the usage of EEG as a tool to assess changes in listening effort by comparing different spatial noise processing algorithms.
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via IFTTT
Spatial Noise Processing in Hearing Aids Modulates Neural Markers Linked to Listening Effort: An EEG Study
The objective of the course is to learn about the usage of EEG as a tool to assess changes in listening effort by comparing different spatial noise processing algorithms.
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Phonak Introduces Marvel Hearing Aids with Real-Time Support and Voice-to-Text Transcription
Phonak has launched Marvel, a revolutionary hearing aid family that combines the benefits of exceptional speech understanding and reduced listening effort in noise with the ability to stream all audio content seamlessly from iPhone, Android smartphone or billions of other Bluetooth enabled devices to both ears in stereo quality. Marvel hearing aids are rechargeable and empower consumers to benefit from remote real-time support via smart apps as well as real-time voice-to-text transcription of phone calls. It has the AutoSense OS™ 3.0 operating system which was developed with artificial intelligence to provide exceptional sound quality from the first fit, better speech understanding in noise, reduced listening effort, and rich sound experience when streaming. The Phonak Audéo™ M will be the first Marvel hearing aid to feature this breakthrough technology.
The Marvel hearing aids include the following features:
- Wearers can stream any audio content, including music, eBooks, and more to both ears from any Bluetooth device
- Built-in microphones allow completely hands-free phone conversations from both iPhone and Android devices while the conversation is heard in both ears
- Lithium-Ion rechargeable option available for a full day of hearing including streaming on a single charge
- Smart apps enable remote fine-tuning and live voice-to-text phone transcriptions
Sound quality
AutoSense OS 3.0 was developed using artificial intelligence, to automatically learn, detect and adapt, providing the best hearing experience in any listening environment.
With Marvel technology, AutoSense OS 3.0 can even classify streamed media. In a recent study1, Audéo M was top-rated for quality of streaming media against five competitors. The enhanced operating system also includes Binaural VoiceStream Technology™ into Marvel hearing aids. This highly-sophisticated four-microphone technology has been proven to significantly improve speech understanding by 60%2 in noisy places like restaurants while simultaneously reducing the amount of effort by 19%3 required to listen and understand.
"Audiology is at the heart of everything we do at Phonak." said Martin Grieder, Group Vice President, Hearing Instruments Marketing at Sonova. "That's why Marvel is such a game-changer for our industry. Marvel technology empowers people and provides a true "love at first sound" experience. We believe the sound quality is second to none, and it begins the moment the person puts the hearing aids on."
Stream from iOS, Android and billions of Bluetooth devices
The Android operating system accounts for 86%4 of all smartphones worldwide, yet until today, binaural (two-ear) streaming of phone calls, music, and other multimedia content directly to hearing aids has only been a reality for iPhone users, who only account for 13% of smartphone owners worldwide. Empowering all consumers regardless of the smartphone operating system has been a driving force behind Phonak. Audéo M is capable of direct audio streaming from virtually any smartphone around the world.
"For years, the hearing aid industry has waited for a single solution that streams phone conversations, music, and video content in stereo from both iPhone and Android devices," said Thomas Lang, Senior Vice President of Marketing at Phonak. "Today, we're proud to announce that the wait is over. Marvel technology gives wearers access to billions of Bluetooth-enabled devices, so people no longer have to think about whether their hearing aids will work with their phones or other personal electronics."
Continuing the rechargeable revolution
There are numerous benefits to not having to change tiny hearing aid batteries, not only for people with vision or dexterity challenges. In fact, rechargeable hearing aids are cited as the top feature most likely to attract potential first-time hearing aid wearers5. In 2016, Phonak released the world's first lithium-ion rechargeable hearing aids and set new standards for efficiency and convenience.
With Marvel hearing aids wearers can enjoy a full day of hearing - including streaming - on a single charge. The Audéo M rechargeable hearing aid turns on automatically when taken out of the charger. Integrated LED lights and a new mini charger provide the usability people expect.
Enhancing the user experience with smart apps
With Marvel hearing aids comes the introduction of a suite of convenient smart apps. The myPhonak app allows wearers to have their hearing aids adjusted in real-time, in any situation, anywhere via video call by the hearing care professional. It also gives consumers the ability to rate their hearing aid satisfaction in various environments and directly send this feedback to their hearing care professional. Finally, the myCall-to-Text app provides live transcription of phone calls from the other party in more than 80 languages. This is an ideal solution for noisy environments, or for people who prefer additional visual captions when using the phone.
The Audéo M will be available in the U.S. beginning the end of November. The new hearing aids are also RogerDirect™ ready, meaning they can receive signals from Roger™ microphones directly and without attaching a separate receiver in the future for better understanding in noise and over distance. RogerDirect functionality will be available as a firmware upgrade in Fall 2019.
REFERENCES:
- Legarth, S., Latzel, M., & Rodrigues, T. (2018). Media streaming: The sound quality wearers prefer. Phonak Field Study News, retrieved from www.phonakpro.com/evidence
- Field Study News about Phonak StereoZoom in preparation, available by end of 2018 at www.phonakpro.com/evidence.
- Winneke, A., Latzel, M., & Appleton-Huber, J. (2018). Less listening- and memory effort in noisy situations with StereoZoom. Phonak Field Study News, retrieved from www.phonakpro.com/evidence
- Global mobile landscape 2016, eMarketer, November 2016
- Marketrak 2015, asked of non-owners only (n=2099) – multiple responses allowed
Published: 10/16/2018 10:48:00 AM
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Phonak Introduces Marvel Hearing Aids with Real-Time Support and Voice-to-Text Transcription
Phonak has launched Marvel, a revolutionary hearing aid family that combines the benefits of exceptional speech understanding and reduced listening effort in noise with the ability to stream all audio content seamlessly from iPhone, Android smartphone or billions of other Bluetooth enabled devices to both ears in stereo quality. Marvel hearing aids are rechargeable and empower consumers to benefit from remote real-time support via smart apps as well as real-time voice-to-text transcription of phone calls. It has the AutoSense OS™ 3.0 operating system which was developed with artificial intelligence to provide exceptional sound quality from the first fit, better speech understanding in noise, reduced listening effort, and rich sound experience when streaming. The Phonak Audéo™ M will be the first Marvel hearing aid to feature this breakthrough technology.
The Marvel hearing aids include the following features:
- Wearers can stream any audio content, including music, eBooks, and more to both ears from any Bluetooth device
- Built-in microphones allow completely hands-free phone conversations from both iPhone and Android devices while the conversation is heard in both ears
- Lithium-Ion rechargeable option available for a full day of hearing including streaming on a single charge
- Smart apps enable remote fine-tuning and live voice-to-text phone transcriptions
Sound quality
AutoSense OS 3.0 was developed using artificial intelligence, to automatically learn, detect and adapt, providing the best hearing experience in any listening environment.
With Marvel technology, AutoSense OS 3.0 can even classify streamed media. In a recent study1, Audéo M was top-rated for quality of streaming media against five competitors. The enhanced operating system also includes Binaural VoiceStream Technology™ into Marvel hearing aids. This highly-sophisticated four-microphone technology has been proven to significantly improve speech understanding by 60%2 in noisy places like restaurants while simultaneously reducing the amount of effort by 19%3 required to listen and understand.
"Audiology is at the heart of everything we do at Phonak." said Martin Grieder, Group Vice President, Hearing Instruments Marketing at Sonova. "That's why Marvel is such a game-changer for our industry. Marvel technology empowers people and provides a true "love at first sound" experience. We believe the sound quality is second to none, and it begins the moment the person puts the hearing aids on."
Stream from iOS, Android and billions of Bluetooth devices
The Android operating system accounts for 86%4 of all smartphones worldwide, yet until today, binaural (two-ear) streaming of phone calls, music, and other multimedia content directly to hearing aids has only been a reality for iPhone users, who only account for 13% of smartphone owners worldwide. Empowering all consumers regardless of the smartphone operating system has been a driving force behind Phonak. Audéo M is capable of direct audio streaming from virtually any smartphone around the world.
"For years, the hearing aid industry has waited for a single solution that streams phone conversations, music, and video content in stereo from both iPhone and Android devices," said Thomas Lang, Senior Vice President of Marketing at Phonak. "Today, we're proud to announce that the wait is over. Marvel technology gives wearers access to billions of Bluetooth-enabled devices, so people no longer have to think about whether their hearing aids will work with their phones or other personal electronics."
Continuing the rechargeable revolution
There are numerous benefits to not having to change tiny hearing aid batteries, not only for people with vision or dexterity challenges. In fact, rechargeable hearing aids are cited as the top feature most likely to attract potential first-time hearing aid wearers5. In 2016, Phonak released the world's first lithium-ion rechargeable hearing aids and set new standards for efficiency and convenience.
With Marvel hearing aids wearers can enjoy a full day of hearing - including streaming - on a single charge. The Audéo M rechargeable hearing aid turns on automatically when taken out of the charger. Integrated LED lights and a new mini charger provide the usability people expect.
Enhancing the user experience with smart apps
With Marvel hearing aids comes the introduction of a suite of convenient smart apps. The myPhonak app allows wearers to have their hearing aids adjusted in real-time, in any situation, anywhere via video call by the hearing care professional. It also gives consumers the ability to rate their hearing aid satisfaction in various environments and directly send this feedback to their hearing care professional. Finally, the myCall-to-Text app provides live transcription of phone calls from the other party in more than 80 languages. This is an ideal solution for noisy environments, or for people who prefer additional visual captions when using the phone.
The Audéo M will be available in the U.S. beginning the end of November. The new hearing aids are also RogerDirect™ ready, meaning they can receive signals from Roger™ microphones directly and without attaching a separate receiver in the future for better understanding in noise and over distance. RogerDirect functionality will be available as a firmware upgrade in Fall 2019.
REFERENCES:
- Legarth, S., Latzel, M., & Rodrigues, T. (2018). Media streaming: The sound quality wearers prefer. Phonak Field Study News, retrieved from www.phonakpro.com/evidence
- Field Study News about Phonak StereoZoom in preparation, available by end of 2018 at www.phonakpro.com/evidence.
- Winneke, A., Latzel, M., & Appleton-Huber, J. (2018). Less listening- and memory effort in noisy situations with StereoZoom. Phonak Field Study News, retrieved from www.phonakpro.com/evidence
- Global mobile landscape 2016, eMarketer, November 2016
- Marketrak 2015, asked of non-owners only (n=2099) – multiple responses allowed
Published: 10/16/2018 10:48:00 AM
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Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
| Related Articles |
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Int J Audiol. 2018 Oct 15;:1-8
Authors: Ling X, Li KZ, Shen B, Si LH, Hong Y, Yang X
Abstract
OBJECTIVE: To investigate the diagnosis and treatment of anterior canal benign paroxysmal positional vertigo (AC-BPPV).
DESIGN: Retrospective analysis of clinical data regarding the diagnosis and treatment of patients with AC-BPPV.
STUDY SAMPLE: Six patients with AC-BPPV.
RESULTS: All patients underwent the Dix-Hallpike test and/or the straight head-hanging test to induce vertigo and down-beating nystagmus with or without torsional components. Down-beating nystagmus in patients 1, 3 and 6 lasted <1 min and was successfully treated with the Yacovino manoeuvre. Down-beating nystagmus in patients 2, 4 and 5 lasted >1 min. The Yacovino manoeuvre was not effective in patient 4, whereas it was effective in patient 2 but with frequently recurring symptoms. Patients 3, 4 and 6 also had other types of typical BPPV. Canal conversion appeared in patients 4 and 5 during the follow-up period.
CONCLUSION: Typical BPPV, canal conversion, a therapeutic diagnosis after applying the Yacovino manoeuvre, and the follow-up outcome contribute to AC-BPPV diagnosis in patients with dizziness and vertigo presenting with down-beating positional nystagmus. Yacovino manoeuvre was more effective in AC-BPPV patients with down-beating positional nystagmus lasted <1 min than in those in whom it lasted >1 min.
PMID: 30318958 [PubMed - as supplied by publisher]
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The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
| Related Articles |
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
Int J Audiol. 2018 Oct 15;:1-9
Authors: Humes LE
Abstract
This review evaluated the data from five datasets having pure-tone thresholds and functional measures of speech communication from relatively large groups of older adults to evaluate the validity of the proposed new World Health Organisation (WHO) hearing-impairment grading system, referred to here as WHO-proposed. This was a review of studies identified from the literature having both pure-tone audiometry and functional measures of speech communication from relatively large samples of older adults. Three population or population-sample datasets and two clinical datasets were identified with access provided to de-identified data for five of these six studies. As the WHO-proposed hearing-impairment grade progressed from "normal" to "severe" (insufficient data from older adults were available for the "profound" category), each step in this progression led to a significant difference in functional communication relative to the preceding step. Cohen's d effect sizes were moderate to very large between each successive step on the WHO-proposed hearing-impairment grading scale, with some exceptions for the step from "normal" to "mild/slight" grades. The WHO-proposed hearing-impairment grading system, recently developed through expert opinion and adopted by WHO, is validated here with evidence from studies of functional communication in older adults.
PMID: 30318941 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yK28TS
via IFTTT
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
| Related Articles |
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Int J Audiol. 2018 Oct 15;:1-8
Authors: Ling X, Li KZ, Shen B, Si LH, Hong Y, Yang X
Abstract
OBJECTIVE: To investigate the diagnosis and treatment of anterior canal benign paroxysmal positional vertigo (AC-BPPV).
DESIGN: Retrospective analysis of clinical data regarding the diagnosis and treatment of patients with AC-BPPV.
STUDY SAMPLE: Six patients with AC-BPPV.
RESULTS: All patients underwent the Dix-Hallpike test and/or the straight head-hanging test to induce vertigo and down-beating nystagmus with or without torsional components. Down-beating nystagmus in patients 1, 3 and 6 lasted <1 min and was successfully treated with the Yacovino manoeuvre. Down-beating nystagmus in patients 2, 4 and 5 lasted >1 min. The Yacovino manoeuvre was not effective in patient 4, whereas it was effective in patient 2 but with frequently recurring symptoms. Patients 3, 4 and 6 also had other types of typical BPPV. Canal conversion appeared in patients 4 and 5 during the follow-up period.
CONCLUSION: Typical BPPV, canal conversion, a therapeutic diagnosis after applying the Yacovino manoeuvre, and the follow-up outcome contribute to AC-BPPV diagnosis in patients with dizziness and vertigo presenting with down-beating positional nystagmus. Yacovino manoeuvre was more effective in AC-BPPV patients with down-beating positional nystagmus lasted <1 min than in those in whom it lasted >1 min.
PMID: 30318958 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yk1Vrj
via IFTTT
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
| Related Articles |
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
Int J Audiol. 2018 Oct 15;:1-9
Authors: Humes LE
Abstract
This review evaluated the data from five datasets having pure-tone thresholds and functional measures of speech communication from relatively large groups of older adults to evaluate the validity of the proposed new World Health Organisation (WHO) hearing-impairment grading system, referred to here as WHO-proposed. This was a review of studies identified from the literature having both pure-tone audiometry and functional measures of speech communication from relatively large samples of older adults. Three population or population-sample datasets and two clinical datasets were identified with access provided to de-identified data for five of these six studies. As the WHO-proposed hearing-impairment grade progressed from "normal" to "severe" (insufficient data from older adults were available for the "profound" category), each step in this progression led to a significant difference in functional communication relative to the preceding step. Cohen's d effect sizes were moderate to very large between each successive step on the WHO-proposed hearing-impairment grading scale, with some exceptions for the step from "normal" to "mild/slight" grades. The WHO-proposed hearing-impairment grading system, recently developed through expert opinion and adopted by WHO, is validated here with evidence from studies of functional communication in older adults.
PMID: 30318941 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yK28TS
via IFTTT
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Int J Audiol. 2018 Oct 15;:1-8
Authors: Ling X, Li KZ, Shen B, Si LH, Hong Y, Yang X
Abstract
OBJECTIVE: To investigate the diagnosis and treatment of anterior canal benign paroxysmal positional vertigo (AC-BPPV).
DESIGN: Retrospective analysis of clinical data regarding the diagnosis and treatment of patients with AC-BPPV.
STUDY SAMPLE: Six patients with AC-BPPV.
RESULTS: All patients underwent the Dix-Hallpike test and/or the straight head-hanging test to induce vertigo and down-beating nystagmus with or without torsional components. Down-beating nystagmus in patients 1, 3 and 6 lasted <1 min and was successfully treated with the Yacovino manoeuvre. Down-beating nystagmus in patients 2, 4 and 5 lasted >1 min. The Yacovino manoeuvre was not effective in patient 4, whereas it was effective in patient 2 but with frequently recurring symptoms. Patients 3, 4 and 6 also had other types of typical BPPV. Canal conversion appeared in patients 4 and 5 during the follow-up period.
CONCLUSION: Typical BPPV, canal conversion, a therapeutic diagnosis after applying the Yacovino manoeuvre, and the follow-up outcome contribute to AC-BPPV diagnosis in patients with dizziness and vertigo presenting with down-beating positional nystagmus. Yacovino manoeuvre was more effective in AC-BPPV patients with down-beating positional nystagmus lasted <1 min than in those in whom it lasted >1 min.
PMID: 30318958 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yk1Vrj
via IFTTT
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
Int J Audiol. 2018 Oct 15;:1-9
Authors: Humes LE
Abstract
This review evaluated the data from five datasets having pure-tone thresholds and functional measures of speech communication from relatively large groups of older adults to evaluate the validity of the proposed new World Health Organisation (WHO) hearing-impairment grading system, referred to here as WHO-proposed. This was a review of studies identified from the literature having both pure-tone audiometry and functional measures of speech communication from relatively large samples of older adults. Three population or population-sample datasets and two clinical datasets were identified with access provided to de-identified data for five of these six studies. As the WHO-proposed hearing-impairment grade progressed from "normal" to "severe" (insufficient data from older adults were available for the "profound" category), each step in this progression led to a significant difference in functional communication relative to the preceding step. Cohen's d effect sizes were moderate to very large between each successive step on the WHO-proposed hearing-impairment grading scale, with some exceptions for the step from "normal" to "mild/slight" grades. The WHO-proposed hearing-impairment grading system, recently developed through expert opinion and adopted by WHO, is validated here with evidence from studies of functional communication in older adults.
PMID: 30318941 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yK28TS
via IFTTT
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Diagnosis and treatment of anterior canal benign paroxysmal positional vertigo.
Int J Audiol. 2018 Oct 15;:1-8
Authors: Ling X, Li KZ, Shen B, Si LH, Hong Y, Yang X
Abstract
OBJECTIVE: To investigate the diagnosis and treatment of anterior canal benign paroxysmal positional vertigo (AC-BPPV).
DESIGN: Retrospective analysis of clinical data regarding the diagnosis and treatment of patients with AC-BPPV.
STUDY SAMPLE: Six patients with AC-BPPV.
RESULTS: All patients underwent the Dix-Hallpike test and/or the straight head-hanging test to induce vertigo and down-beating nystagmus with or without torsional components. Down-beating nystagmus in patients 1, 3 and 6 lasted <1 min and was successfully treated with the Yacovino manoeuvre. Down-beating nystagmus in patients 2, 4 and 5 lasted >1 min. The Yacovino manoeuvre was not effective in patient 4, whereas it was effective in patient 2 but with frequently recurring symptoms. Patients 3, 4 and 6 also had other types of typical BPPV. Canal conversion appeared in patients 4 and 5 during the follow-up period.
CONCLUSION: Typical BPPV, canal conversion, a therapeutic diagnosis after applying the Yacovino manoeuvre, and the follow-up outcome contribute to AC-BPPV diagnosis in patients with dizziness and vertigo presenting with down-beating positional nystagmus. Yacovino manoeuvre was more effective in AC-BPPV patients with down-beating positional nystagmus lasted <1 min than in those in whom it lasted >1 min.
PMID: 30318958 [PubMed - as supplied by publisher]
from #Audiology via ola Kala on Inoreader https://ift.tt/2yk1Vrj
via IFTTT
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
The World Health Organization's hearing-impairment grading system: an evaluation for unaided communication in age-related hearing loss.
Int J Audiol. 2018 Oct 15;:1-9
Authors: Humes LE
Abstract
This review evaluated the data from five datasets having pure-tone thresholds and functional measures of speech communication from relatively large groups of older adults to evaluate the validity of the proposed new World Health Organisation (WHO) hearing-impairment grading system, referred to here as WHO-proposed. This was a review of studies identified from the literature having both pure-tone audiometry and functional measures of speech communication from relatively large samples of older adults. Three population or population-sample datasets and two clinical datasets were identified with access provided to de-identified data for five of these six studies. As the WHO-proposed hearing-impairment grade progressed from "normal" to "severe" (insufficient data from older adults were available for the "profound" category), each step in this progression led to a significant difference in functional communication relative to the preceding step. Cohen's d effect sizes were moderate to very large between each successive step on the WHO-proposed hearing-impairment grading scale, with some exceptions for the step from "normal" to "mild/slight" grades. The WHO-proposed hearing-impairment grading system, recently developed through expert opinion and adopted by WHO, is validated here with evidence from studies of functional communication in older adults.
PMID: 30318941 [PubMed - as supplied by publisher]
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Syndromic hearing loss molecular diagnosis: application of massive parallel sequencing
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Yasmin Soares de Lima, Marcela Chiabai, Jun Shen, Mara S. Córdoba, Beatriz R. Versiani, Rosenelle.O.A. Benício, Robert Pogue, Regina Célia Mingroni-Netto, Karina Lezirovitz, Aline Pic-Taylor, Juliana F. Mazzeu, Silviene F. Oliveira
Abstract
Syndromic hearing loss accounts for approximately 30% of all cases of hearing loss due to genetic causes. Mutation screening in known genes is important because it potentially sheds light on the genetic etiology of hearing loss and helps in genetic counseling of families. In this study, we describe a customized Ion AmpliSeq Panel, specifically designed for the investigation of syndromic hearing loss. The Ion AmpliSeq Panel was customized to cover the coding sequences of 52 genes. Twenty-four patients were recruited: 17 patients with a clinical diagnosis of a known syndrome, and seven whose clinical signs did not allow identification of a syndrome. Of 24 patients sequenced, potentially causative mutations were found in nine, all of which belonged to the group with a previous clinical diagnostic and none in the group not clinically diagnosed. We were able to provide conclusive molecular diagnosis to six patients, constituting a diagnostic rate of 25% (6/24). In the group of patients with a suspected clinical diagnosis, the diagnostic rate was 35% (6/17). Of the nine different mutations identified, three are novel, and were found in patients with Waardenburg, Treacher Collins and CHARGE syndromes. Since all patients with a conclusive molecular diagnosis through this panel had a previous suspected clinical diagnosis, our results suggest that this panel was more effective in diagnosing this group of patients. Therefore, the panel demonstrated effectiveness in molecular diagnosis when compared to others in the literature, especially for patients with a defined clinical diagnosis.
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Mechanical Properties of the Papio anubis Tympanic Membrane: Change Significantly from Infancy to Adulthood
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Junfeng Liang, Kyle D. Smith, Hongbing Lu, Thomas W. Seale, Rong Z. Gan
Abstract
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of the unavailability of temporal bones from children. In this study, we used the baboon (Papio anubis), a genetically close human relative, as a model to address the occurrence of age-dependent changes of the human TM. Forty-five baboon TMs were characterized in five age groups: <1 year, 1 to <2 years, 2 to <3 years, 3 to <5, and >5 years of age, comparable to human ages ranging from newborn to adult. The elastic properties of the baboon TMs were characterized by a micro-fringe projection technique. Volume displacement of the TM under quasi-static pressure was first determined from its micro-fringe pattern. Subsequently, these displacement values were used in a finite element model to derive mechanical properties. The Young’s modulus of the baboon TM exhibited a modest decrease from 29.1 MPa to 26.0 MPa over the age groups. The average Young’s modulus was ∼1.4 times higher than that of the adult human TM. This is the first time that age-related TM mechanical properties of high primate are reported. These new findings may help to explore the potential value of the baboon as a new primate model for future age-related hearing research on the normal and diseased ear.
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Comment on Greene et al.: Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth
Publication date: Available online 15 October 2018
Source: Hearing Research
Author(s): Henry E. Heffner, Rickye S. Heffner
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Syndromic hearing loss molecular diagnosis: application of massive parallel sequencing
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Yasmin Soares de Lima, Marcela Chiabai, Jun Shen, Mara S. Córdoba, Beatriz R. Versiani, Rosenelle.O.A. Benício, Robert Pogue, Regina Célia Mingroni-Netto, Karina Lezirovitz, Aline Pic-Taylor, Juliana F. Mazzeu, Silviene F. Oliveira
Abstract
Syndromic hearing loss accounts for approximately 30% of all cases of hearing loss due to genetic causes. Mutation screening in known genes is important because it potentially sheds light on the genetic etiology of hearing loss and helps in genetic counseling of families. In this study, we describe a customized Ion AmpliSeq Panel, specifically designed for the investigation of syndromic hearing loss. The Ion AmpliSeq Panel was customized to cover the coding sequences of 52 genes. Twenty-four patients were recruited: 17 patients with a clinical diagnosis of a known syndrome, and seven whose clinical signs did not allow identification of a syndrome. Of 24 patients sequenced, potentially causative mutations were found in nine, all of which belonged to the group with a previous clinical diagnostic and none in the group not clinically diagnosed. We were able to provide conclusive molecular diagnosis to six patients, constituting a diagnostic rate of 25% (6/24). In the group of patients with a suspected clinical diagnosis, the diagnostic rate was 35% (6/17). Of the nine different mutations identified, three are novel, and were found in patients with Waardenburg, Treacher Collins and CHARGE syndromes. Since all patients with a conclusive molecular diagnosis through this panel had a previous suspected clinical diagnosis, our results suggest that this panel was more effective in diagnosing this group of patients. Therefore, the panel demonstrated effectiveness in molecular diagnosis when compared to others in the literature, especially for patients with a defined clinical diagnosis.
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Mechanical Properties of the Papio anubis Tympanic Membrane: Change Significantly from Infancy to Adulthood
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Junfeng Liang, Kyle D. Smith, Hongbing Lu, Thomas W. Seale, Rong Z. Gan
Abstract
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of the unavailability of temporal bones from children. In this study, we used the baboon (Papio anubis), a genetically close human relative, as a model to address the occurrence of age-dependent changes of the human TM. Forty-five baboon TMs were characterized in five age groups: <1 year, 1 to <2 years, 2 to <3 years, 3 to <5, and >5 years of age, comparable to human ages ranging from newborn to adult. The elastic properties of the baboon TMs were characterized by a micro-fringe projection technique. Volume displacement of the TM under quasi-static pressure was first determined from its micro-fringe pattern. Subsequently, these displacement values were used in a finite element model to derive mechanical properties. The Young’s modulus of the baboon TM exhibited a modest decrease from 29.1 MPa to 26.0 MPa over the age groups. The average Young’s modulus was ∼1.4 times higher than that of the adult human TM. This is the first time that age-related TM mechanical properties of high primate are reported. These new findings may help to explore the potential value of the baboon as a new primate model for future age-related hearing research on the normal and diseased ear.
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Comment on Greene et al.: Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth
Publication date: Available online 15 October 2018
Source: Hearing Research
Author(s): Henry E. Heffner, Rickye S. Heffner
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Syndromic hearing loss molecular diagnosis: application of massive parallel sequencing
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Yasmin Soares de Lima, Marcela Chiabai, Jun Shen, Mara S. Córdoba, Beatriz R. Versiani, Rosenelle.O.A. Benício, Robert Pogue, Regina Célia Mingroni-Netto, Karina Lezirovitz, Aline Pic-Taylor, Juliana F. Mazzeu, Silviene F. Oliveira
Abstract
Syndromic hearing loss accounts for approximately 30% of all cases of hearing loss due to genetic causes. Mutation screening in known genes is important because it potentially sheds light on the genetic etiology of hearing loss and helps in genetic counseling of families. In this study, we describe a customized Ion AmpliSeq Panel, specifically designed for the investigation of syndromic hearing loss. The Ion AmpliSeq Panel was customized to cover the coding sequences of 52 genes. Twenty-four patients were recruited: 17 patients with a clinical diagnosis of a known syndrome, and seven whose clinical signs did not allow identification of a syndrome. Of 24 patients sequenced, potentially causative mutations were found in nine, all of which belonged to the group with a previous clinical diagnostic and none in the group not clinically diagnosed. We were able to provide conclusive molecular diagnosis to six patients, constituting a diagnostic rate of 25% (6/24). In the group of patients with a suspected clinical diagnosis, the diagnostic rate was 35% (6/17). Of the nine different mutations identified, three are novel, and were found in patients with Waardenburg, Treacher Collins and CHARGE syndromes. Since all patients with a conclusive molecular diagnosis through this panel had a previous suspected clinical diagnosis, our results suggest that this panel was more effective in diagnosing this group of patients. Therefore, the panel demonstrated effectiveness in molecular diagnosis when compared to others in the literature, especially for patients with a defined clinical diagnosis.
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Mechanical Properties of the Papio anubis Tympanic Membrane: Change Significantly from Infancy to Adulthood
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Junfeng Liang, Kyle D. Smith, Hongbing Lu, Thomas W. Seale, Rong Z. Gan
Abstract
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of the unavailability of temporal bones from children. In this study, we used the baboon (Papio anubis), a genetically close human relative, as a model to address the occurrence of age-dependent changes of the human TM. Forty-five baboon TMs were characterized in five age groups: <1 year, 1 to <2 years, 2 to <3 years, 3 to <5, and >5 years of age, comparable to human ages ranging from newborn to adult. The elastic properties of the baboon TMs were characterized by a micro-fringe projection technique. Volume displacement of the TM under quasi-static pressure was first determined from its micro-fringe pattern. Subsequently, these displacement values were used in a finite element model to derive mechanical properties. The Young’s modulus of the baboon TM exhibited a modest decrease from 29.1 MPa to 26.0 MPa over the age groups. The average Young’s modulus was ∼1.4 times higher than that of the adult human TM. This is the first time that age-related TM mechanical properties of high primate are reported. These new findings may help to explore the potential value of the baboon as a new primate model for future age-related hearing research on the normal and diseased ear.
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Comment on Greene et al.: Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth
Publication date: Available online 15 October 2018
Source: Hearing Research
Author(s): Henry E. Heffner, Rickye S. Heffner
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Syndromic hearing loss molecular diagnosis: application of massive parallel sequencing
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Yasmin Soares de Lima, Marcela Chiabai, Jun Shen, Mara S. Córdoba, Beatriz R. Versiani, Rosenelle.O.A. Benício, Robert Pogue, Regina Célia Mingroni-Netto, Karina Lezirovitz, Aline Pic-Taylor, Juliana F. Mazzeu, Silviene F. Oliveira
Abstract
Syndromic hearing loss accounts for approximately 30% of all cases of hearing loss due to genetic causes. Mutation screening in known genes is important because it potentially sheds light on the genetic etiology of hearing loss and helps in genetic counseling of families. In this study, we describe a customized Ion AmpliSeq Panel, specifically designed for the investigation of syndromic hearing loss. The Ion AmpliSeq Panel was customized to cover the coding sequences of 52 genes. Twenty-four patients were recruited: 17 patients with a clinical diagnosis of a known syndrome, and seven whose clinical signs did not allow identification of a syndrome. Of 24 patients sequenced, potentially causative mutations were found in nine, all of which belonged to the group with a previous clinical diagnostic and none in the group not clinically diagnosed. We were able to provide conclusive molecular diagnosis to six patients, constituting a diagnostic rate of 25% (6/24). In the group of patients with a suspected clinical diagnosis, the diagnostic rate was 35% (6/17). Of the nine different mutations identified, three are novel, and were found in patients with Waardenburg, Treacher Collins and CHARGE syndromes. Since all patients with a conclusive molecular diagnosis through this panel had a previous suspected clinical diagnosis, our results suggest that this panel was more effective in diagnosing this group of patients. Therefore, the panel demonstrated effectiveness in molecular diagnosis when compared to others in the literature, especially for patients with a defined clinical diagnosis.
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Mechanical Properties of the Papio anubis Tympanic Membrane: Change Significantly from Infancy to Adulthood
Publication date: Available online 16 October 2018
Source: Hearing Research
Author(s): Junfeng Liang, Kyle D. Smith, Hongbing Lu, Thomas W. Seale, Rong Z. Gan
Abstract
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of the unavailability of temporal bones from children. In this study, we used the baboon (Papio anubis), a genetically close human relative, as a model to address the occurrence of age-dependent changes of the human TM. Forty-five baboon TMs were characterized in five age groups: <1 year, 1 to <2 years, 2 to <3 years, 3 to <5, and >5 years of age, comparable to human ages ranging from newborn to adult. The elastic properties of the baboon TMs were characterized by a micro-fringe projection technique. Volume displacement of the TM under quasi-static pressure was first determined from its micro-fringe pattern. Subsequently, these displacement values were used in a finite element model to derive mechanical properties. The Young’s modulus of the baboon TM exhibited a modest decrease from 29.1 MPa to 26.0 MPa over the age groups. The average Young’s modulus was ∼1.4 times higher than that of the adult human TM. This is the first time that age-related TM mechanical properties of high primate are reported. These new findings may help to explore the potential value of the baboon as a new primate model for future age-related hearing research on the normal and diseased ear.
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Comment on Greene et al.: Spatial hearing ability of the pigmented Guinea pig (Cavia porcellus): Minimum audible angle and spatial release from masking in azimuth
Publication date: Available online 15 October 2018
Source: Hearing Research
Author(s): Henry E. Heffner, Rickye S. Heffner
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Can Computerized Dynamic Posturography detect measured CVEMP and OVEMP abnormalities?
Publication date: Available online 16 October 2018
Source: Gait & Posture
Author(s): Arthur I. Mallinson, Anouk C.M. Kuijpers, Gusta Van Zwieten, Juzer Kakal, Warren Mullings, Neil S. Longridge
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Immediate effects of real-time postural biofeedback on spinal posture, muscle activity, and perceived pain severity in adults with neck pain
Publication date: Available online 15 October 2018
Source: Gait & Posture
Author(s): Yi-Liang Kuo, Pei-San Wang, Po-Yen Ko, Kuo-Yuan Huang, Yi-Ju Tsai
Abstract
Background
Previous studies have investigated various types of postural biofeedback devices on different body regions to improve posture; however, they focused only on healthy adults without a history of chronic musculoskeletal disorders. In addition, those postural biofeedback devices used in previous studies are often designed for experimental research. The designs are usually bulky with many wires, which is not practical for everyday use.
Research question
The aim of this study was to determine the immediate effect of a commercially available real-time postural biofeedback device on spinal posture, muscle activity, and perceived pain severity in adults with neck pain.
Methods
21 adults who had chronic or recurrent nonspecific neck pain for more than 3 months and whose pain was induced or aggravated by prolonged computer work were enrolled in this study. Spinal posture (head tilt, neck flexion, cervical and thoracic angles), muscle activity (cervical erector spinae, upper trapezius, and thoracic erector spinae), and self-reported neck and shoulder pain were measured during computer typing tasks, with and without biofeedback.
Results
Compared with the non-biofeedback condition, the biofeedback condition significantly decreased neck flexion, upper cervical, and lower thoracic angles and lowered the activity of the cervical erector spinae. Self-reported neck pain was not influenced by the application of biofeedback, but significantly increased over the 1-hour typing task.
Significance
The application of a commercially available wearable real-time biofeedback device improves sitting posture and reduces muscular activity in adults with nonspecific neck pain during computer work. Future studies should examine the long-term effects of wearable real-time postural biofeedback devices for prevention and management of neck pain.
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Can Computerized Dynamic Posturography detect measured CVEMP and OVEMP abnormalities?
Publication date: Available online 16 October 2018
Source: Gait & Posture
Author(s): Arthur I. Mallinson, Anouk C.M. Kuijpers, Gusta Van Zwieten, Juzer Kakal, Warren Mullings, Neil S. Longridge
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Immediate effects of real-time postural biofeedback on spinal posture, muscle activity, and perceived pain severity in adults with neck pain
Publication date: Available online 15 October 2018
Source: Gait & Posture
Author(s): Yi-Liang Kuo, Pei-San Wang, Po-Yen Ko, Kuo-Yuan Huang, Yi-Ju Tsai
Abstract
Background
Previous studies have investigated various types of postural biofeedback devices on different body regions to improve posture; however, they focused only on healthy adults without a history of chronic musculoskeletal disorders. In addition, those postural biofeedback devices used in previous studies are often designed for experimental research. The designs are usually bulky with many wires, which is not practical for everyday use.
Research question
The aim of this study was to determine the immediate effect of a commercially available real-time postural biofeedback device on spinal posture, muscle activity, and perceived pain severity in adults with neck pain.
Methods
21 adults who had chronic or recurrent nonspecific neck pain for more than 3 months and whose pain was induced or aggravated by prolonged computer work were enrolled in this study. Spinal posture (head tilt, neck flexion, cervical and thoracic angles), muscle activity (cervical erector spinae, upper trapezius, and thoracic erector spinae), and self-reported neck and shoulder pain were measured during computer typing tasks, with and without biofeedback.
Results
Compared with the non-biofeedback condition, the biofeedback condition significantly decreased neck flexion, upper cervical, and lower thoracic angles and lowered the activity of the cervical erector spinae. Self-reported neck pain was not influenced by the application of biofeedback, but significantly increased over the 1-hour typing task.
Significance
The application of a commercially available wearable real-time biofeedback device improves sitting posture and reduces muscular activity in adults with nonspecific neck pain during computer work. Future studies should examine the long-term effects of wearable real-time postural biofeedback devices for prevention and management of neck pain.
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Bilateral Vestibulopathy Due to Severe Cochlear Otosclerosis: A Well-Known Condition Without Any Favorable Solution.
Bilateral Vestibulopathy Due to Severe Cochlear Otosclerosis: A Well-Known Condition Without Any Favorable Solution.
Turk Arch Otorhinolaryngol. 2018 Sep;56(3):174-176
Authors: Yetişer S
Abstract
Bilateral vestibulopathy is a rare condition. It is one of the most difficult balance problems to treat because nearly all patients experience long-term unsteadiness. In this report, a 39-year-old woman gradually developing chronic dizziness and instability due to bilateral vestibulopathy as a result of progressive severe cochlear otosclerosis was presented with review of the literature.
PMID: 30319876 [PubMed]
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Bilateral Vestibulopathy Due to Severe Cochlear Otosclerosis: A Well-Known Condition Without Any Favorable Solution.
Bilateral Vestibulopathy Due to Severe Cochlear Otosclerosis: A Well-Known Condition Without Any Favorable Solution.
Turk Arch Otorhinolaryngol. 2018 Sep;56(3):174-176
Authors: Yetişer S
Abstract
Bilateral vestibulopathy is a rare condition. It is one of the most difficult balance problems to treat because nearly all patients experience long-term unsteadiness. In this report, a 39-year-old woman gradually developing chronic dizziness and instability due to bilateral vestibulopathy as a result of progressive severe cochlear otosclerosis was presented with review of the literature.
PMID: 30319876 [PubMed]
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