Παρασκευή 15 Απριλίου 2016

Characteristics of Auditory Processing Disorders: A Systematic Review

Purpose
The purpose of this review article is to describe characteristics of auditory processing disorders (APD) by evaluating the literature in which children with suspected or diagnosed APD were compared with typically developing children and to determine whether APD must be regarded as a deficit specific to the auditory modality or as a multimodal deficit.
Method
Six electronic databases were searched for peer-reviewed studies investigating children with (suspected) APD in comparison with typically developing peers. Relevant studies were independently reviewed and appraised by 2 reviewers. Methodological quality was quantified using the American Speech-Language-Hearing Association's levels of evidence.
Results
Fifty-three relevant studies were identified. Five studies were excluded because of weak internal validity. In total, 48 studies were included, of which only 1 was classified as having strong methodological quality. Significant dissimilarities were found between children referred with listening difficulties and controls. These differences relate to auditory and visual functioning, cognition, language, reading, and physiological and neuroimaging measures.
Conclusions
Methodological quality of most of the incorporated studies was rated moderate due to the heterogeneous groups of participants, inadequate descriptions of participants, and the omission of valid and reliable measurements. The listening difficulties of children with APD may be a consequence of cognitive, language, and attention issues rather than bottom-up auditory processing.

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Characteristics of Auditory Processing Disorders: A Systematic Review

Purpose
The purpose of this review article is to describe characteristics of auditory processing disorders (APD) by evaluating the literature in which children with suspected or diagnosed APD were compared with typically developing children and to determine whether APD must be regarded as a deficit specific to the auditory modality or as a multimodal deficit.
Method
Six electronic databases were searched for peer-reviewed studies investigating children with (suspected) APD in comparison with typically developing peers. Relevant studies were independently reviewed and appraised by 2 reviewers. Methodological quality was quantified using the American Speech-Language-Hearing Association's levels of evidence.
Results
Fifty-three relevant studies were identified. Five studies were excluded because of weak internal validity. In total, 48 studies were included, of which only 1 was classified as having strong methodological quality. Significant dissimilarities were found between children referred with listening difficulties and controls. These differences relate to auditory and visual functioning, cognition, language, reading, and physiological and neuroimaging measures.
Conclusions
Methodological quality of most of the incorporated studies was rated moderate due to the heterogeneous groups of participants, inadequate descriptions of participants, and the omission of valid and reliable measurements. The listening difficulties of children with APD may be a consequence of cognitive, language, and attention issues rather than bottom-up auditory processing.

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Characteristics of Auditory Processing Disorders: A Systematic Review

Purpose
The purpose of this review article is to describe characteristics of auditory processing disorders (APD) by evaluating the literature in which children with suspected or diagnosed APD were compared with typically developing children and to determine whether APD must be regarded as a deficit specific to the auditory modality or as a multimodal deficit.
Method
Six electronic databases were searched for peer-reviewed studies investigating children with (suspected) APD in comparison with typically developing peers. Relevant studies were independently reviewed and appraised by 2 reviewers. Methodological quality was quantified using the American Speech-Language-Hearing Association's levels of evidence.
Results
Fifty-three relevant studies were identified. Five studies were excluded because of weak internal validity. In total, 48 studies were included, of which only 1 was classified as having strong methodological quality. Significant dissimilarities were found between children referred with listening difficulties and controls. These differences relate to auditory and visual functioning, cognition, language, reading, and physiological and neuroimaging measures.
Conclusions
Methodological quality of most of the incorporated studies was rated moderate due to the heterogeneous groups of participants, inadequate descriptions of participants, and the omission of valid and reliable measurements. The listening difficulties of children with APD may be a consequence of cognitive, language, and attention issues rather than bottom-up auditory processing.

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Acoustic vector sensor beamforming reduces masking from underwater industrial noise during passive monitoring

Masking from industrial noise can hamper the ability to detect marine mammal sounds near industrial operations, whenever conventional (pressuresensor)hydrophones are used for passive acoustic monitoring. Using data collected from an autonomous recorder with directional capabilities (Directional Autonomous Seafloor Acoustic Recorder), deployed 4.1 km from an arctic drilling site in 2012, the authors demonstrate how conventional beamforming on an acoustic vector sensor can be used to suppress noise arriving from a narrow sector of geographic azimuths. Improvements in signal-to-noise ratio of up to 15 dB are demonstrated on bowhead whale calls, which were otherwise undetectable using conventional hydrophones.



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Identification and quantification of soundscape components in the Marginal Ice Zone

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Acoustic experiments using an integrated ice station were carried out during August 2012 and September 2013 in the Marginal Ice Zone (MIZ) of Fram Strait. The two experiments lasted four days each and collected under-ice acoustic recordings together with wave-in-ice and meteorological data. Synthetic aperture radar satellite data provided information on regional ice conditions. Four major components of the under-ice soundscape were identified: shipcavitationnoise,seismic airgun noise, marine mammal vocalizations, and natural background noise.Shipcavitationnoise was connected to heavy icebreaking. It dominated the soundscape at times, with noise levels (NLs) 100 km from the icebreaker increased by 10–28 dB. Seismic airgun noise that originated from seismic surveys more than 800 km away was present during 117 out of 188 observation hours. It increased NLs at 20–120 Hz by 2–6 dB. Marine mammal vocalizations were a minor influence on measured NLs, but their prevalence shows the biological importance of the MIZ. The 10th percentile of the noise distributions was used to identify the ambient background noise. Background NLs above 100 Hz differed by 12 dB between the two experiments, presumably due to variations in natural noise sources.



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Acoustic vector sensor beamforming reduces masking from underwater industrial noise during passive monitoring

Masking from industrial noise can hamper the ability to detect marine mammal sounds near industrial operations, whenever conventional (pressuresensor)hydrophones are used for passive acoustic monitoring. Using data collected from an autonomous recorder with directional capabilities (Directional Autonomous Seafloor Acoustic Recorder), deployed 4.1 km from an arctic drilling site in 2012, the authors demonstrate how conventional beamforming on an acoustic vector sensor can be used to suppress noise arriving from a narrow sector of geographic azimuths. Improvements in signal-to-noise ratio of up to 15 dB are demonstrated on bowhead whale calls, which were otherwise undetectable using conventional hydrophones.



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Electrophysiologic vestibular evaluation in type 2 diabetic and prediabetic patients: Air conduction ocular and cervical vestibular evoked myogenic potentials.

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Electrophysiologic vestibular evaluation in type 2 diabetic and prediabetic patients: Air conduction ocular and cervical vestibular evoked myogenic potentials.

Int J Audiol. 2015 Aug;54(8):536-43

Authors: Konukseven O, Polat SB, Karahan S, Konukseven E, Ersoy R, Cakir B, Kutluhan A, Aksoy S

Abstract
OBJECTIVE: Chronically increased blood glucose levels may affect the vestibular system by damaging cells and neural structures in diabetes mellitus (DM). We aimed to search the effects of neurovascular degeneration on the vestibular system in type 2 DM and prediabetic patients by using air-conducted ocular (oVEMP) and cervical (cVEMP) vestibular evoked myogenic potentials.
DESIGN: Prospective study.
STUDY SAMPLE: Thirty diabetic, 30 prediabetic patients, and 31 age- and sex-matched controls having no peripheral or central vestibular disease, were enrolled. All participants were evaluated by audiovestibular tests, oVEMP, and cVEMP.
RESULTS: In the diabetic group, mean values of both oVEMP and cVEMP p1, n1 latencies were significantly longer compared to the prediabetic group and the control group, whereas latencies were similar in prediabetic and the control groups. Bilateral neural dysfunction was recognized in both tests and lateralization was not seen in VEMP asymmetric ratios. In the diabetic group, prevalence of pathological p1 and n1 latencies in oVEMP were 30.4% and 37.5%, whereas they were 53.7%, 59.3% in cVEMP, respectively. p1 latencies of cVEMP and oVEMP were positively correlated with HbA1c and fasting plasma glucose level in the diabetic group.
CONCLUSION: Subclinical vestibular neuropathy can be a newly defined diabetes-related complication.

PMID: 25529975 [PubMed - indexed for MEDLINE]



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Electrophysiologic vestibular evaluation in type 2 diabetic and prediabetic patients: Air conduction ocular and cervical vestibular evoked myogenic potentials.

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Electrophysiologic vestibular evaluation in type 2 diabetic and prediabetic patients: Air conduction ocular and cervical vestibular evoked myogenic potentials.

Int J Audiol. 2015 Aug;54(8):536-43

Authors: Konukseven O, Polat SB, Karahan S, Konukseven E, Ersoy R, Cakir B, Kutluhan A, Aksoy S

Abstract
OBJECTIVE: Chronically increased blood glucose levels may affect the vestibular system by damaging cells and neural structures in diabetes mellitus (DM). We aimed to search the effects of neurovascular degeneration on the vestibular system in type 2 DM and prediabetic patients by using air-conducted ocular (oVEMP) and cervical (cVEMP) vestibular evoked myogenic potentials.
DESIGN: Prospective study.
STUDY SAMPLE: Thirty diabetic, 30 prediabetic patients, and 31 age- and sex-matched controls having no peripheral or central vestibular disease, were enrolled. All participants were evaluated by audiovestibular tests, oVEMP, and cVEMP.
RESULTS: In the diabetic group, mean values of both oVEMP and cVEMP p1, n1 latencies were significantly longer compared to the prediabetic group and the control group, whereas latencies were similar in prediabetic and the control groups. Bilateral neural dysfunction was recognized in both tests and lateralization was not seen in VEMP asymmetric ratios. In the diabetic group, prevalence of pathological p1 and n1 latencies in oVEMP were 30.4% and 37.5%, whereas they were 53.7%, 59.3% in cVEMP, respectively. p1 latencies of cVEMP and oVEMP were positively correlated with HbA1c and fasting plasma glucose level in the diabetic group.
CONCLUSION: Subclinical vestibular neuropathy can be a newly defined diabetes-related complication.

PMID: 25529975 [PubMed - indexed for MEDLINE]



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Parents' perspectives on the dilemmas with intervention for infants with auditory neuropathy spectrum disorder: A qualitative study.

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Parents' perspectives on the dilemmas with intervention for infants with auditory neuropathy spectrum disorder: A qualitative study.

Int J Audiol. 2015 Aug;54(8):552-8

Authors: Uus K, Young A, Day M

Abstract
OBJECTIVE: This paper explores parental experiences of choices surrounding auditory management and language and communication development for infants and children with auditory neuropathy spectrum disorder (ANSD) in the light of the heterogeneity of condition, a poor evidence base for best outcomes in relation to management options, and the scarcity of data rooted in parent and family experience.
DESIGN: Qualitative narrative study.
STUDY SAMPLE: Twenty-five parents of 21 children (aged four months to six years) identified with ANSD through the newborn hearing screening programme.
RESULTS: Families identify barriers to early management due to conflicting expert opinions and ANSD-specific challenges with diagnosis and prognosis in infants, and share their accounts on their own evaluations of intervention benefit in their children.
CONCLUSIONS: The results are of relevance to the clinicians and other professionals involved in early intervention, management, and support of infants with ANSD.

PMID: 25826252 [PubMed - indexed for MEDLINE]



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Hearing aid and cochlear implant use in children with hearing loss at three years of age: Predictors of use and predictors of changes in use.

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Hearing aid and cochlear implant use in children with hearing loss at three years of age: Predictors of use and predictors of changes in use.

Int J Audiol. 2015 Aug;54(8):544-51

Authors: Marnane V, Ching TY

Abstract
OBJECTIVE: To examine usage patterns of hearing aids and cochlear implants in children up to three years of age, how usage changes longitudinally, and factors associated with device usage.
DESIGN: Parent report and Parent's Evaluation of Aural/oral Performance of Children (PEACH) data were obtained at six and twelve months after hearing-aid fitting or cochlear implant switch-on, and again at three years of age. The effect of device use on auditory functional performance was investigated using the PEACH questionnaire.
STUDY SAMPLE: Four hundred and thirteen participants from the Longitudinal Outcomes of Children with Hearing Impairment (LOCHI) study were included for analysis.
RESULTS: For users of hearing aids, higher usage at three years was associated with higher maternal education, and more severe hearing loss. For users of cochlear implants, higher usage was associated with higher maternal education and the absence of additional disabilities. Higher PEACH scores were associated with higher usage scores. After allowing for the effects of demographic characteristics, device use was not a significant predictor of functional performance.
CONCLUSIONS: Sixty-two percent of children achieved consistent use (> 75% of waking hours) within the first year of receiving a hearing aid or a cochlear implant, and 71% by three years of age.

PMID: 25816866 [PubMed - indexed for MEDLINE]



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The audiological journey and early outcomes of twelve infants with auditory neuropathy spectrum disorder from birth to two years of age.

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The audiological journey and early outcomes of twelve infants with auditory neuropathy spectrum disorder from birth to two years of age.

Int J Audiol. 2015 Aug;54(8):524-35

Authors: Gardner-Berry K, Purdy SC, Ching TY, Dillon H

Abstract
OBJECTIVE: To describe the audiological journey of a group of infants with auditory neuropathy spectrum disorder (ANSD) following the fitting of hearing aids, and to investigate the potential benefits of including cortical auditory-evoked potentials (CAEPs) and a measure of functional auditory behaviour during early audiological management.
DESIGN: Results from chart revision of estimated hearing threshold, early behavioural testing, parental observation, and functional auditory behaviour assessments were described, and compared to visual reinforcement audiometry (VRA) thresholds obtained at a mean corrected age of 10 months (SD 3). The relationship with CAEPs and functional performance was examined.
STUDY SAMPLE: The study included 12 infants diagnosed with ANSD and fitted with amplification.
RESULTS: The estimated 4FA at a mean corrected age of four months (SD5) was within ± 10 dB of VRA results in 75% of infants when unaided and aided behavioural observation audiometry (BOA), together with unaided and aided parental observations was combined. Infants with a greater proportion of CAEPs present had higher PEACH scores.
CONCLUSIONS: Delaying amplification until VRA results were available would have led to a significant period of auditory deprivation for infants in this study group. None of the assessments could accurately determine hearing thresholds when used in isolation, however when used in combination clinicians were able to obtain sufficient information to fit hearing aids early, and identify infants requiring closer monitoring.

PMID: 25812580 [PubMed - indexed for MEDLINE]



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Early onset hearing loss in autosomal recessive hypophosphatemic rickets caused by loss of function mutation in ENPP1.

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Early onset hearing loss in autosomal recessive hypophosphatemic rickets caused by loss of function mutation in ENPP1.

J Pediatr Endocrinol Metab. 2015 Jul;28(7-8):967-70

Authors: Steichen-Gersdorf E, Lorenz-Depiereux B, Strom TM, Shaw NJ

Abstract
Autosomal recessive hypophosphatemic rickets 2 (ARHR2) is a rare form of renal tubular phosphate wasting disorder. Loss of function mutations of the ecto-nucleotide pyrophosphatase/pyrophosphodiesterase 1 gene (ENPP1) causes a wide spectrum of phenotypes, ranging from lethal generalized arterial calcification of infancy to hypophosphatemic rickets with hypertension. Hearing loss was not previously thought to be one of the features of the disease entities and was merely regarded as a complication rather than a part of the disease. We report two children who presented in mid to late childhood with progressive varus deformity of their legs due to hypophosphatemic rickets caused by mutations in the ENPP1 gene. Both children had evidence of progressive hearing loss requiring the use of hearing aids. This report of two unrelated infants with compound heterozygous mutations in ENPP1 and previously published cases confirms that mild to moderate hearing loss is frequently associated with ARHR2. Early onset conductive hearing loss may further distinguish the autosomal recessive ENPP1 related type from other types of hypophosphatemia.

PMID: 25741938 [PubMed - indexed for MEDLINE]



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Exploring the Source of Neural Responses of Different Latencies Obtained from Different Recording Electrodes in Cochlear Implant Users

In this study we measured the electrically evoked compound action potential (ECAP) from different recording electrodes in the cochlea. Under the assumption that different response latencies may be the result of differences in the neural population contributing to the response, we assessed the relationship between neural response latency and spread of excitation. First, we evaluated changes in N1 latency when the recording electrode site was varied. Second, we recorded channel interaction functions using a forward masking technique but with recording electrodes at different intracochlear locations. For most individuals, N1 latency was similar across recording electrodes. However, reduced N1 latencies were observed in 21% of cochlear implant users when ECAPs were recorded using a remote recording electrode. We hypothesized that if recordings from different electrodes represented contributions from different populations of neurons, then one might expect that channel interaction functions would be different. However, we did not observe consistent differences in channel interaction functions (neither peak location nor breadth of the functions), and further, any variation in channel interaction functions was not correlated with ECAP latency. These results suggest that ECAPs from different recording electrodes with different latencies originate from similar neural populations.
Audiol Neurotol 2016;21:141-149

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