Πέμπτη 4 Οκτωβρίου 2018

Subtypes of GABAergic Cells in the Inferior Colliculus

Publication date: Available online 4 October 2018

Source: Hearing Research

Author(s): Brett R. Schofield, Nichole L. Beebe

Abstract

The inferior colliculus occupies a central position in ascending and descending auditory pathways. A substantial proportion of its neurons are GABAergic, and these neurons contribute to intracollicular circuits as well as to extrinsic projections to numerous targets. A variety of types of evidence – morphology, physiology, molecular markers – indicate that the GABAergic cells can be divided into at least four subtypes that serve different functions. However, there has yet to emerge a unified scheme for distinguishing these subtypes. The present review discusses these criteria and, where possible, relates the different properties. In contrast to GABAergic cells in cerebral cortex, where subtypes are much more thoroughly characterized, those in the inferior colliculus contribute substantially to numerous long range extrinsic projections. At present, the best characterized subtype is a GABAergic cell with a large soma, dense perisomatic synaptic inputs and a large axon that provides rapid auditory input to the thalamus. This large GABAergic subtype projects to additional targets, and other subtypes also project to the thalamus. The eventual characterization of these subtypes can be expected to reveal multiple functions of these inhibitory cells and the many circuits to which they contribute.



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Assessing the background decomposition of a complex auditory scene with event-related brain potentials

Publication date: Available online 3 October 2018

Source: Hearing Research

Author(s): Sabine Thomassen, Alexandra Bendixen

Abstract

A listener who focusses on a sound source of interest must continuously integrate the sounds emitted by the attended source and ignore the sounds emitted by the remaining sources in the auditory scene. Little is known about how the ignored sound sources in the background are mentally represented after the source of interest has formed the perceptual foreground. This is due to a key methodological challenge: the background representation is by definition not overtly reportable. Here we developed a paradigm based on event-related brain potentials (ERPs) to assess the mental representation of background sounds. Participants listened to sequences of three repeatedly presented tones arranged in an ascending order (low, middle, high frequency). They were instructed to detect intensity deviants in one of the tones, creating the perceptual foreground. The remaining two background tones contained timing and location deviants. Those deviants were set up such that mismatch negativity (MMN) components would be elicited in distinct ways if the background was decomposed into two separate sound streams (background segregation) or if it was not further decomposed (background integration). Results provide MMN-based evidence for background segregation and integration in parallel. This suggests that mental representations of background integration and segregation can be concurrently available, and that collecting empirical evidence for only one of these background organization alternatives might lead to erroneous conclusions.



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Subtypes of GABAergic Cells in the Inferior Colliculus

Publication date: Available online 4 October 2018

Source: Hearing Research

Author(s): Brett R. Schofield, Nichole L. Beebe

Abstract

The inferior colliculus occupies a central position in ascending and descending auditory pathways. A substantial proportion of its neurons are GABAergic, and these neurons contribute to intracollicular circuits as well as to extrinsic projections to numerous targets. A variety of types of evidence – morphology, physiology, molecular markers – indicate that the GABAergic cells can be divided into at least four subtypes that serve different functions. However, there has yet to emerge a unified scheme for distinguishing these subtypes. The present review discusses these criteria and, where possible, relates the different properties. In contrast to GABAergic cells in cerebral cortex, where subtypes are much more thoroughly characterized, those in the inferior colliculus contribute substantially to numerous long range extrinsic projections. At present, the best characterized subtype is a GABAergic cell with a large soma, dense perisomatic synaptic inputs and a large axon that provides rapid auditory input to the thalamus. This large GABAergic subtype projects to additional targets, and other subtypes also project to the thalamus. The eventual characterization of these subtypes can be expected to reveal multiple functions of these inhibitory cells and the many circuits to which they contribute.



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Assessing the background decomposition of a complex auditory scene with event-related brain potentials

Publication date: Available online 3 October 2018

Source: Hearing Research

Author(s): Sabine Thomassen, Alexandra Bendixen

Abstract

A listener who focusses on a sound source of interest must continuously integrate the sounds emitted by the attended source and ignore the sounds emitted by the remaining sources in the auditory scene. Little is known about how the ignored sound sources in the background are mentally represented after the source of interest has formed the perceptual foreground. This is due to a key methodological challenge: the background representation is by definition not overtly reportable. Here we developed a paradigm based on event-related brain potentials (ERPs) to assess the mental representation of background sounds. Participants listened to sequences of three repeatedly presented tones arranged in an ascending order (low, middle, high frequency). They were instructed to detect intensity deviants in one of the tones, creating the perceptual foreground. The remaining two background tones contained timing and location deviants. Those deviants were set up such that mismatch negativity (MMN) components would be elicited in distinct ways if the background was decomposed into two separate sound streams (background segregation) or if it was not further decomposed (background integration). Results provide MMN-based evidence for background segregation and integration in parallel. This suggests that mental representations of background integration and segregation can be concurrently available, and that collecting empirical evidence for only one of these background organization alternatives might lead to erroneous conclusions.



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Subtypes of GABAergic Cells in the Inferior Colliculus

Publication date: Available online 4 October 2018

Source: Hearing Research

Author(s): Brett R. Schofield, Nichole L. Beebe

Abstract

The inferior colliculus occupies a central position in ascending and descending auditory pathways. A substantial proportion of its neurons are GABAergic, and these neurons contribute to intracollicular circuits as well as to extrinsic projections to numerous targets. A variety of types of evidence – morphology, physiology, molecular markers – indicate that the GABAergic cells can be divided into at least four subtypes that serve different functions. However, there has yet to emerge a unified scheme for distinguishing these subtypes. The present review discusses these criteria and, where possible, relates the different properties. In contrast to GABAergic cells in cerebral cortex, where subtypes are much more thoroughly characterized, those in the inferior colliculus contribute substantially to numerous long range extrinsic projections. At present, the best characterized subtype is a GABAergic cell with a large soma, dense perisomatic synaptic inputs and a large axon that provides rapid auditory input to the thalamus. This large GABAergic subtype projects to additional targets, and other subtypes also project to the thalamus. The eventual characterization of these subtypes can be expected to reveal multiple functions of these inhibitory cells and the many circuits to which they contribute.



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Assessing the background decomposition of a complex auditory scene with event-related brain potentials

Publication date: Available online 3 October 2018

Source: Hearing Research

Author(s): Sabine Thomassen, Alexandra Bendixen

Abstract

A listener who focusses on a sound source of interest must continuously integrate the sounds emitted by the attended source and ignore the sounds emitted by the remaining sources in the auditory scene. Little is known about how the ignored sound sources in the background are mentally represented after the source of interest has formed the perceptual foreground. This is due to a key methodological challenge: the background representation is by definition not overtly reportable. Here we developed a paradigm based on event-related brain potentials (ERPs) to assess the mental representation of background sounds. Participants listened to sequences of three repeatedly presented tones arranged in an ascending order (low, middle, high frequency). They were instructed to detect intensity deviants in one of the tones, creating the perceptual foreground. The remaining two background tones contained timing and location deviants. Those deviants were set up such that mismatch negativity (MMN) components would be elicited in distinct ways if the background was decomposed into two separate sound streams (background segregation) or if it was not further decomposed (background integration). Results provide MMN-based evidence for background segregation and integration in parallel. This suggests that mental representations of background integration and segregation can be concurrently available, and that collecting empirical evidence for only one of these background organization alternatives might lead to erroneous conclusions.



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Subtypes of GABAergic Cells in the Inferior Colliculus

Publication date: Available online 4 October 2018

Source: Hearing Research

Author(s): Brett R. Schofield, Nichole L. Beebe

Abstract

The inferior colliculus occupies a central position in ascending and descending auditory pathways. A substantial proportion of its neurons are GABAergic, and these neurons contribute to intracollicular circuits as well as to extrinsic projections to numerous targets. A variety of types of evidence – morphology, physiology, molecular markers – indicate that the GABAergic cells can be divided into at least four subtypes that serve different functions. However, there has yet to emerge a unified scheme for distinguishing these subtypes. The present review discusses these criteria and, where possible, relates the different properties. In contrast to GABAergic cells in cerebral cortex, where subtypes are much more thoroughly characterized, those in the inferior colliculus contribute substantially to numerous long range extrinsic projections. At present, the best characterized subtype is a GABAergic cell with a large soma, dense perisomatic synaptic inputs and a large axon that provides rapid auditory input to the thalamus. This large GABAergic subtype projects to additional targets, and other subtypes also project to the thalamus. The eventual characterization of these subtypes can be expected to reveal multiple functions of these inhibitory cells and the many circuits to which they contribute.



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Assessing the background decomposition of a complex auditory scene with event-related brain potentials

Publication date: Available online 3 October 2018

Source: Hearing Research

Author(s): Sabine Thomassen, Alexandra Bendixen

Abstract

A listener who focusses on a sound source of interest must continuously integrate the sounds emitted by the attended source and ignore the sounds emitted by the remaining sources in the auditory scene. Little is known about how the ignored sound sources in the background are mentally represented after the source of interest has formed the perceptual foreground. This is due to a key methodological challenge: the background representation is by definition not overtly reportable. Here we developed a paradigm based on event-related brain potentials (ERPs) to assess the mental representation of background sounds. Participants listened to sequences of three repeatedly presented tones arranged in an ascending order (low, middle, high frequency). They were instructed to detect intensity deviants in one of the tones, creating the perceptual foreground. The remaining two background tones contained timing and location deviants. Those deviants were set up such that mismatch negativity (MMN) components would be elicited in distinct ways if the background was decomposed into two separate sound streams (background segregation) or if it was not further decomposed (background integration). Results provide MMN-based evidence for background segregation and integration in parallel. This suggests that mental representations of background integration and segregation can be concurrently available, and that collecting empirical evidence for only one of these background organization alternatives might lead to erroneous conclusions.



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Kinematic adaptation and changes in gait classification in running compared to walking in children with unilateral spastic cerebral palsy

Publication date: Available online 3 October 2018

Source: Gait & Posture

Author(s): Rafael Krätschmer, Harald Böhm, Leonhard Döderlein

Abstract
Background

Classification of sagittal gait patterns in unilateral spastic cerebral palsy (CP) provides direct implication for treatment. Five types are described: type 0 has minor gait deviation; type 1 has inadequate ankle dorsiflexion in swing; type 2 has inadequate ankle dorsiflexion throughout the gait cycle; types 3 and 4 have abnormal function of the knee and hip joint respectively. During gait analysis of children with unilateral spastic CP we observed frequently that a knee flexion deficit disappeared during running. That may have an impact on classification and treatment.

Research question

Does the classification type change while running and how do patients’ kinematics adapt to running?

Methods

64 children with unilateral spastic CP were classified using instrumented gait analysis for walking and running. The deviation of four parameters from typically developing children (TD) were used to distinguish between types: peak ankle dorsiflexion in swing for type 1, peak ankle dorsiflexion in stance for type 2, knee range of motion for type 3, and hip range of motion for type 4. A three-factor ANOVA for factors group (CP/TD), locomotion (walk/run) and limb side (in-/uninvolved) was conducted.

Results

The number of patients with type 1, 3 and 4 decreased considerably from walking to running, whereas, the number of type 0 and 2 patients increased. The ANOVA showed that three of four parameters of patients’ pathologic limb adapt similarly to TD to running, except for the ankle dorsiflexion in stance.

Significance

Running shows that there is a natural way to resolve abnormalities. Therefore, recommended treatments of hip and knee joint abnormalities based on the walking classification can be questioned and additional running analysis may be important for surgical decision making.



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Kinematic adaptation and changes in gait classification in running compared to walking in children with unilateral spastic cerebral palsy

Publication date: Available online 3 October 2018

Source: Gait & Posture

Author(s): Rafael Krätschmer, Harald Böhm, Leonhard Döderlein

Abstract
Background

Classification of sagittal gait patterns in unilateral spastic cerebral palsy (CP) provides direct implication for treatment. Five types are described: type 0 has minor gait deviation; type 1 has inadequate ankle dorsiflexion in swing; type 2 has inadequate ankle dorsiflexion throughout the gait cycle; types 3 and 4 have abnormal function of the knee and hip joint respectively. During gait analysis of children with unilateral spastic CP we observed frequently that a knee flexion deficit disappeared during running. That may have an impact on classification and treatment.

Research question

Does the classification type change while running and how do patients’ kinematics adapt to running?

Methods

64 children with unilateral spastic CP were classified using instrumented gait analysis for walking and running. The deviation of four parameters from typically developing children (TD) were used to distinguish between types: peak ankle dorsiflexion in swing for type 1, peak ankle dorsiflexion in stance for type 2, knee range of motion for type 3, and hip range of motion for type 4. A three-factor ANOVA for factors group (CP/TD), locomotion (walk/run) and limb side (in-/uninvolved) was conducted.

Results

The number of patients with type 1, 3 and 4 decreased considerably from walking to running, whereas, the number of type 0 and 2 patients increased. The ANOVA showed that three of four parameters of patients’ pathologic limb adapt similarly to TD to running, except for the ankle dorsiflexion in stance.

Significance

Running shows that there is a natural way to resolve abnormalities. Therefore, recommended treatments of hip and knee joint abnormalities based on the walking classification can be questioned and additional running analysis may be important for surgical decision making.



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Factors Associated With Successful Setup of a Self-Fitting Hearing Aid and the Need for Personalized Support

Objectives: Self-fitting hearing aids have the potential to increase the accessibility of hearing health care. The aims of this study were to (1) identify factors that are associated with the ability to successfully set up a pair of commercially available self-fitting hearing aids; 2) identify factors that are associated with the need for knowledgeable, personalized support in performing the self-fitting procedure; and (3) evaluate performance of the individual steps in the self-fitting procedure. Design: Sixty adults with hearing loss between the ages of 51 and 85 took part in the study. Half of the participants were current users of bilateral hearing aids; the other half had no previous hearing aid experience. At the first appointment, participants underwent assessments of health locus of control, hearing aid self-efficacy, cognitive status, problem-solving skills, demographic characteristics, and hearing thresholds. At the second appointment, participants followed a set of computer-based instructions accompanied by video clips to self-fit the hearing aids. The self-fitting procedure required participants to customize the physical fit of the hearing aids, insert the hearing aids into the ear, perform self-directed in situ audiometry, and adjust the resultant settings according to their preference. Participants had access to support with the self-fitting procedure from a trained clinical assistant (CA) at all times. Results: Forty-one (68%) of the participants achieved a successful self-fitting. Participants who self-fit successfully were significantly more likely than those who were unsuccessful to have had previous experience with hearing aids and to own a mobile device (when controlling for four potential covariates). Of the 41 successful self-fitters, 15 (37%) performed the procedure independently and 26 (63%) sought support from the CA. The successful self-fitters who sought CA support were more likely than those who self-fit independently to have a health locus of control that is externally oriented toward powerful others. Success rates on the individual steps in the self-fitting procedure were relatively high. No one step was more problematic than any other, nor was there a systematic tendency for particular participants to make more errors than others. Steps that required use of the hearing aids in conjunction with the self-fitting app on the participant’s mobile device had the highest rates of support use. Conclusions: The findings of this study suggest that nonaudiologic factors should be considered when selecting suitable candidates for the self-fitting hearing aids evaluated in this study. Although computer-based instructions and video clips were shown to improve self-fitting skill acquisition relative to past studies in which printed instruction booklets were used, the majority of people are still likely to require access to support from trained personnel while carrying out the self-fitting procedure, especially when this requires the use of an app. ACKNOWLEDGEMENTS: The authors thank Shawn Stahmer and Stavros Basseas of SoundWorld Solutions for providing the hearing aids and app used in this study and for their ongoing support during data collection. The authors additionally thank Mark Seeto, Vivian Fabricatorian, Scott Brewer, and Pamela Jackson of the National Acoustic Laboratories and Jamie Macaulay of Macquarie University for their contributions to this study. Preliminary results were presented at Hearing Across the Lifespan (HeAL), Lake Como, Italy, in June 2016; the International Hearing Aid Research Conference (IHCON), Lake Tahoe, CA, in August 2016; the XXXIII World Congress of Audiology, Vancouver, in September 2016; the 44th Annual American Auditory Society Scientific and Technology Meeting, Scottsdale, AZ, in March 2017; the 21st ENT World Congress, Paris, in June 2017; Cutting-Edge Perspectives in Service Delivery for Older Adults, American Speech-Language-Hearing Association Online Conference, October 2017; the 14th Annual British Academy of Audiology Conference, Bournemouth, UK, in November 2017; and the 23rd Audiology Australia National Conference, Sydney, in May 2018. The authors acknowledge the financial support of the HEARing CRC, established under the Australian Government’s Cooperative Research Centres (CRC) Program. The CRC Program supports industry-led collaborations between industry, researchers, and the community. The first author (E.C.) received financial remuneration from the American Auditory Society for her presentation of these findings at the 44th Annual American Auditory Society Scientific and Technology Meeting, Scottsdale, AZ, in March 2017. Address for correspondence: Elizabeth Convery, National Acoustic Laboratories, Level 4, Australian Hearing Hub, 16 University Avenue, Macquarie University NSW 2109, Australia. E-mail: elizabeth.convery@nal.gov.au Received April 16, 2018; accepted August 4, 2018. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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Bimodal Hearing or Bilateral Cochlear Implants? Ask the Patient

Objective: The objectives of this study were to assess the effectiveness of various measures of speech understanding in distinguishing performance differences between adult bimodal and bilateral cochlear implant (CI) recipients and to provide a preliminary evidence-based tool guiding clinical decisions regarding bilateral CI candidacy. Design: This study used a multiple-baseline, cross-sectional design investigating speech recognition performance for 85 experienced adult CI recipients (49 bimodal, 36 bilateral). Speech recognition was assessed in a standard clinical test environment with a single loudspeaker using the minimum speech test battery for adult CI recipients as well as with an R-SPACETM 8-loudspeaker, sound-simulation system. All participants were tested in three listening conditions for each measure including each ear alone as well as in the bilateral/bimodal condition. In addition, we asked each bimodal listener to provide a yes/no answer to the question, “Do you think you need a second CI?” Results: This study yielded three primary findings: (1) there were no significant differences between bimodal and bilateral CI performance or binaural summation on clinical measures of speech recognition, (2) an adaptive speech recognition task in the R-SPACETM system revealed significant differences in performance and binaural summation between bimodal and bilateral CI users, with bilateral CI users achieving significantly better performance and greater summation, and (3) the patient’s answer to the question, “Do you think you need a second CI?” held high sensitivity (100% hit rate) for identifying likely bilateral CI candidates and moderately high specificity (77% correct rejection rate) for correctly identifying listeners best suited with a bimodal hearing configuration. Conclusions: Clinics cannot rely on current clinical measures of speech understanding, with a single loudspeaker, to determine bilateral CI candidacy for adult bimodal listeners nor to accurately document bilateral benefit relative to a previous bimodal hearing configuration. Speech recognition in a complex listening environment, such as R-SPACETM, is a sensitive and appropriate measure for determining bilateral CI candidacy and also likely for documenting bilateral benefit relative to a previous bimodal configuration. In the absence of an available R-SPACETM system, asking the patient whether or not s/he thinks s/he needs a second CI is a highly sensitive measure, which may prove clinically useful. ACKNOWLEDGMENTS: This work was supported by NIH R01 DC009404 and NIH R01 DC010821. Portions of this dataset were presented at the 2015 meeting of the Acoustical Society of America in Pittsburgh, PA, and the 2018 International Conference on Cochlear Implants and other Implantable Auditory Technologies (CI2018) in Antwerp, Belgium. Michael Dorman is a consultant for Advanced Bionics and MED-EL. Rene Gifford is a member of the audiology advisory boards for Advanced Bionics and Cochlear and the clinical advisory board for Frequency Therapeutics. Address for correspondence: René H. Gifford, Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA. E-mail: rene.gifford@Vanderbilt.edu Received October 5, 2017; accepted August 2, 2018. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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Factors Associated With Successful Setup of a Self-Fitting Hearing Aid and the Need for Personalized Support

Objectives: Self-fitting hearing aids have the potential to increase the accessibility of hearing health care. The aims of this study were to (1) identify factors that are associated with the ability to successfully set up a pair of commercially available self-fitting hearing aids; 2) identify factors that are associated with the need for knowledgeable, personalized support in performing the self-fitting procedure; and (3) evaluate performance of the individual steps in the self-fitting procedure. Design: Sixty adults with hearing loss between the ages of 51 and 85 took part in the study. Half of the participants were current users of bilateral hearing aids; the other half had no previous hearing aid experience. At the first appointment, participants underwent assessments of health locus of control, hearing aid self-efficacy, cognitive status, problem-solving skills, demographic characteristics, and hearing thresholds. At the second appointment, participants followed a set of computer-based instructions accompanied by video clips to self-fit the hearing aids. The self-fitting procedure required participants to customize the physical fit of the hearing aids, insert the hearing aids into the ear, perform self-directed in situ audiometry, and adjust the resultant settings according to their preference. Participants had access to support with the self-fitting procedure from a trained clinical assistant (CA) at all times. Results: Forty-one (68%) of the participants achieved a successful self-fitting. Participants who self-fit successfully were significantly more likely than those who were unsuccessful to have had previous experience with hearing aids and to own a mobile device (when controlling for four potential covariates). Of the 41 successful self-fitters, 15 (37%) performed the procedure independently and 26 (63%) sought support from the CA. The successful self-fitters who sought CA support were more likely than those who self-fit independently to have a health locus of control that is externally oriented toward powerful others. Success rates on the individual steps in the self-fitting procedure were relatively high. No one step was more problematic than any other, nor was there a systematic tendency for particular participants to make more errors than others. Steps that required use of the hearing aids in conjunction with the self-fitting app on the participant’s mobile device had the highest rates of support use. Conclusions: The findings of this study suggest that nonaudiologic factors should be considered when selecting suitable candidates for the self-fitting hearing aids evaluated in this study. Although computer-based instructions and video clips were shown to improve self-fitting skill acquisition relative to past studies in which printed instruction booklets were used, the majority of people are still likely to require access to support from trained personnel while carrying out the self-fitting procedure, especially when this requires the use of an app. ACKNOWLEDGEMENTS: The authors thank Shawn Stahmer and Stavros Basseas of SoundWorld Solutions for providing the hearing aids and app used in this study and for their ongoing support during data collection. The authors additionally thank Mark Seeto, Vivian Fabricatorian, Scott Brewer, and Pamela Jackson of the National Acoustic Laboratories and Jamie Macaulay of Macquarie University for their contributions to this study. Preliminary results were presented at Hearing Across the Lifespan (HeAL), Lake Como, Italy, in June 2016; the International Hearing Aid Research Conference (IHCON), Lake Tahoe, CA, in August 2016; the XXXIII World Congress of Audiology, Vancouver, in September 2016; the 44th Annual American Auditory Society Scientific and Technology Meeting, Scottsdale, AZ, in March 2017; the 21st ENT World Congress, Paris, in June 2017; Cutting-Edge Perspectives in Service Delivery for Older Adults, American Speech-Language-Hearing Association Online Conference, October 2017; the 14th Annual British Academy of Audiology Conference, Bournemouth, UK, in November 2017; and the 23rd Audiology Australia National Conference, Sydney, in May 2018. The authors acknowledge the financial support of the HEARing CRC, established under the Australian Government’s Cooperative Research Centres (CRC) Program. The CRC Program supports industry-led collaborations between industry, researchers, and the community. The first author (E.C.) received financial remuneration from the American Auditory Society for her presentation of these findings at the 44th Annual American Auditory Society Scientific and Technology Meeting, Scottsdale, AZ, in March 2017. Address for correspondence: Elizabeth Convery, National Acoustic Laboratories, Level 4, Australian Hearing Hub, 16 University Avenue, Macquarie University NSW 2109, Australia. E-mail: elizabeth.convery@nal.gov.au Received April 16, 2018; accepted August 4, 2018. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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Bimodal Hearing or Bilateral Cochlear Implants? Ask the Patient

Objective: The objectives of this study were to assess the effectiveness of various measures of speech understanding in distinguishing performance differences between adult bimodal and bilateral cochlear implant (CI) recipients and to provide a preliminary evidence-based tool guiding clinical decisions regarding bilateral CI candidacy. Design: This study used a multiple-baseline, cross-sectional design investigating speech recognition performance for 85 experienced adult CI recipients (49 bimodal, 36 bilateral). Speech recognition was assessed in a standard clinical test environment with a single loudspeaker using the minimum speech test battery for adult CI recipients as well as with an R-SPACETM 8-loudspeaker, sound-simulation system. All participants were tested in three listening conditions for each measure including each ear alone as well as in the bilateral/bimodal condition. In addition, we asked each bimodal listener to provide a yes/no answer to the question, “Do you think you need a second CI?” Results: This study yielded three primary findings: (1) there were no significant differences between bimodal and bilateral CI performance or binaural summation on clinical measures of speech recognition, (2) an adaptive speech recognition task in the R-SPACETM system revealed significant differences in performance and binaural summation between bimodal and bilateral CI users, with bilateral CI users achieving significantly better performance and greater summation, and (3) the patient’s answer to the question, “Do you think you need a second CI?” held high sensitivity (100% hit rate) for identifying likely bilateral CI candidates and moderately high specificity (77% correct rejection rate) for correctly identifying listeners best suited with a bimodal hearing configuration. Conclusions: Clinics cannot rely on current clinical measures of speech understanding, with a single loudspeaker, to determine bilateral CI candidacy for adult bimodal listeners nor to accurately document bilateral benefit relative to a previous bimodal hearing configuration. Speech recognition in a complex listening environment, such as R-SPACETM, is a sensitive and appropriate measure for determining bilateral CI candidacy and also likely for documenting bilateral benefit relative to a previous bimodal configuration. In the absence of an available R-SPACETM system, asking the patient whether or not s/he thinks s/he needs a second CI is a highly sensitive measure, which may prove clinically useful. ACKNOWLEDGMENTS: This work was supported by NIH R01 DC009404 and NIH R01 DC010821. Portions of this dataset were presented at the 2015 meeting of the Acoustical Society of America in Pittsburgh, PA, and the 2018 International Conference on Cochlear Implants and other Implantable Auditory Technologies (CI2018) in Antwerp, Belgium. Michael Dorman is a consultant for Advanced Bionics and MED-EL. Rene Gifford is a member of the audiology advisory boards for Advanced Bionics and Cochlear and the clinical advisory board for Frequency Therapeutics. Address for correspondence: René H. Gifford, Department of Hearing and Speech Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA. E-mail: rene.gifford@Vanderbilt.edu Received October 5, 2017; accepted August 2, 2018. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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The Middle Latency Response: A Review of Findings in Various Central Nervous System Lesions.

Related Articles

The Middle Latency Response: A Review of Findings in Various Central Nervous System Lesions.

J Am Acad Audiol. 2018 Oct;29(9):855-867

Authors: Musiek F, Nagle S

Abstract
BACKGROUND: The middle latency response (MLR) first came to light as an auditory evoked potential in 1958. Since then, it has aroused substantial interest and investigation by clinicians and researchers alike. In recent history, its use and popularity have dwindled in tandem with various other auditory evoked potentials in audiology. One area for which MLR research and application has been overlooked is its potential value in measuring the neural integrity of the auditory thalamocortical pathway. In a broader sense, the MLR, when combined with the auditory brain stem response, can provide information concerning the status of much of the central auditory system pathways. This review is intended to provide information concerning the MLR as a measure of central auditory function for the reader to consider.
PURPOSE: To review and synthesize the scientific literature regarding the potential value of the MLR in assessing the integrity of the central auditory system and to provide the reader an informed perspective on the value of the MLR in this regard. Information is also provided on the MLR generator sites and fundamental characteristics of this evoked potential essential to its clinical and or research application.
RESEARCH DESIGN: A systematic review and synthesis of the literature focusing on the MLR and lesions of the central auditory system.
STUDY SAMPLE: Studies and individual cases were reviewed and analyzed that evidenced documented lesions of the central auditory nervous system.
DATA COLLECTION AND ANALYSIS: The authors searched and reviewed the literature (journal articles, book chapters, and books) pertaining to central auditory system lesion effects on the MLR.
RESULTS: Although findings varied from study to study, overall, the MLR was reasonably sensitive and specific to neurological compromise of the central auditory system. This finding is consistent with the generator sites of this evoked potential.
CONCLUSIONS: The MLR is a valuable tool for assessing the integrity of the central auditory system. It should be of interest to the clinician or researcher who focuses their attention on the function and dysfunction of the higher auditory system.

PMID: 30278870 [PubMed - in process]



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Refining Stimulus Parameters in Assessing Infant Speech Perception Using Visual Reinforcement Infant Speech Discrimination in Infants with and without Hearing Loss: Presentation Level.

Related Articles

Refining Stimulus Parameters in Assessing Infant Speech Perception Using Visual Reinforcement Infant Speech Discrimination in Infants with and without Hearing Loss: Presentation Level.

J Am Acad Audiol. 2018 Oct;29(9):847-854

Authors: Uhler KM, Gifford RH, Forster JE, Anderson M, Tierney E, Claycomb SD, Werner LA

PMID: 30278869 [PubMed - in process]



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Impact of Consistency in Daily Device Use on Speech Perception Abilities in Children with Cochlear Implants: Datalogging Evidence.

Related Articles

Impact of Consistency in Daily Device Use on Speech Perception Abilities in Children with Cochlear Implants: Datalogging Evidence.

J Am Acad Audiol. 2018 Oct;29(9):835-846

Authors: Easwar V, Sanfilippo J, Papsin B, Gordon K

Abstract
BACKGROUND: Cochlear implants (CIs) give children with severe to profound hearing loss access to sound. There appears to be a dose effect of sound exposure on speech perception abilities as shown by the positive influence of early implantation and CI experience. The consistency in device use per day could also affect sound dose, potentially affecting perceptual abilities in children with CIs.
PURPOSE: The objectives of the present study were to identify the impact of consistency in device use on: (1) speech perception abilities and (2) asymmetry in speech perception abilities between bilateral CIs.
RESEARCH DESIGN: Retrospective analysis.
STUDY SAMPLE: To achieve the first objective, data from 65 children (age range at speech test: 1.91-18.05 yrs) with one (unilaterally implanted or bimodal) or two CIs (sequentially or simultaneously implanted) were included. A subset of data from 40 children with bilateral CIs was included to achieve the second objective. Of the 40 children with two CIs, 15 received their CIs sequentially.
DATA COLLECTION AND ANALYSIS: Device use information was extracted from datalogs stored in personal speech processors using custom software. Speech perception scores per CI collected in quiet were also evaluated. Multiple regression was used to assess the impact of daily CI use, while controlling for factors previously identified to affect speech perception: age at speech test, length of pre-CI (acoustic) hearing experience, length of CI hearing experience, and order of CI for the first objective, and CI category (simultaneous/sequential implantation), interimplant delay, and length of CI experience for the second objective.
RESULTS: On average, children wore their CIs for 11.59 ± 2.86 hours/day and, with one CI, exhibited 65.07 ± 22.64% accuracy on speech perception tests. Higher monaural speech perception scores were associated with longer everyday CI use and CI experience (p < 0.05). Among children with bilateral CIs, those with simultaneously implanted CIs and similar bilateral hearing experience demonstrated a small but significant right ear advantage with higher speech perception scores when using the right rather than left CI (mean difference = 4.55 ± 9.83%). The asymmetry in speech perception between CIs was larger and more variable in children who received their CIs sequentially (mean difference CI1-CI2 = 27.48 ± 24.87%). These asymmetries decreased with longer/consistent everyday use of the newer CI (p < 0.05). Yet, despite consistent everyday device use of the second CI (>12 hours/day), only a small proportion of children implanted sequentially (one out of seven children) achieved symmetrical function similar to children with simultaneously received bilateral CIs.
CONCLUSIONS: Consistent everyday CI use contributes to higher speech perception scores. Although consistent CI use can help reduce the asymmetry in speech perception abilities of children with sequentially implanted CIs subsequent to interimplant delay, residual asymmetry often persists.

PMID: 30278868 [PubMed - in process]



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Accounting for the Occlusion Effect with Insert Earphones.

Related Articles

Accounting for the Occlusion Effect with Insert Earphones.

J Am Acad Audiol. 2018 Oct;29(9):826-834

Authors: Neave-DiToro D, DeSantolo A, Bergen M, Rubinstein A

Abstract
BACKGROUND: There are clinical implications associated with knowing when the occlusion effect (OE) must be accounted for during bone conduction (BC) testing because spurious results can occur when errors are made in this regard. The amount of OE produced when insert earphones (IEs) are used varies in the literature; thus, further investigation is warranted.
PURPOSE: The purpose of this project was to determine the OE during BC threshold measurements under the following occluding conditions used clinically: when using partial insertion (PI) versus full insertion (FI) depth and when occluding one versus both ears.
RESEARCH DESIGN: A descriptive within-subjects design was used in this study.
STUDY SAMPLE: Twenty-two adults with mean four-frequency pure tone averages of 24 dB HL, aged 40-83 yr, participated.
INTERVENTION: BC thresholds were obtained at 250, 500, and 1000 Hz under seven conditions: (1) both ears unoccluded, (2) left ear occluded with PI, (3) right ear occluded with PI, (4) both ears occluded with PI, (5) left ear occluded with FI, (6) right ear occluded with FI, (7) both ears occluded with FI. For PI, one half of the length of the IE was beyond the opening of the ear canal. For FI, the lateral edge of the foam insert was flush with the entrance to the ear canal.
DATA COLLECTION AND ANALYSIS: Mean OEs were compared with previously published data. In addition, variability in the data was examined using frequency distribution plots as well as cumulative frequency and percentile values.
RESULTS: Mean OEs of 5-13 dB were present in all but the FI condition at 1000 Hz where the OE was <3 dB. Differences between PI and FI conditions were present at each frequency measured, irrespective of whether one or both ears were occluded. The shifts in threshold were consistently more prevalent and greater for the PI than the FI conditions overall. Mean differences between the one-ear and both-ears conditions were not clinically significant. Clinically significant variability in the data was noted, except when comparing the one-ear versus both-ears conditions.
CONCLUSIONS: Occluding the ear during initial BC measurements may artificially improve the thresholds and create or exaggerate an air-bone gap. Thus, initial BC testing should be performed unoccluded at 250, 500, and 1000 Hz. There is a need to account for the OE even when the IE is flush with the ear canal to avoid insufficient masking.

PMID: 30278867 [PubMed - in process]



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Using Microphone Technology to Improve Speech Perception in Noise in Children with Cochlear Implants.

Related Articles

Using Microphone Technology to Improve Speech Perception in Noise in Children with Cochlear Implants.

J Am Acad Audiol. 2018 Oct;29(9):814-825

Authors: Johnstone PM, Mills KET, Humphrey E, Yeager KR, Jones E, McElligott K, Pierce A, Agrawal S, Froeling C, Little JP

Abstract
BACKGROUND: Cochlear implant (CI) users are affected more than their normal hearing (NH) peers by the negative consequences of background noise on speech understanding. Research has shown that adult CI users can improve their speech recognition in challenging listening environments by using dual-microphone beamformers, such as adaptive directional microphones (ADMs) and wireless remote microphones (RMs). The suitability of these microphone technologies for use in children with CIs is not well-understood nor widely accepted.
PURPOSE: To assess the benefit of ADM or RM technology on speech perception in background noise in children and adolescents with cochlear implants (CIs) with no previous or current use of ADM or RM.
RESEARCH DESIGN: Mixed, repeated measures design.
STUDY SAMPLE: Twenty (20) children, ten (10) CI users (mean age 14.3 yrs) who used Advanced Bionics HiRes90K implants with research Naida processors, and ten (10) NH age-matched controls participated in this prospective study.
INTERVENTION: CI users listened with an ear-canal level microphone, T-Mic (TM), an ADM, and a wireless RM at different audio-mixing ratios. Speech understanding with five microphone settings (TM 100%, ADM, RM + TM 50/50, RM + TM 75/25, RM 100%) was evaluated in quiet and in noise.
DATA COLLECTION AND ANALYSIS: Speech perception ability was measured using children's spondee words to obtain a speech recognition threshold for 80% accuracy (SRT80%) in 20-talker babble where the listener sat in a sound booth 1 m (3.28') from the target speech (front) and noise (behind) to test five microphone settings (TM 100%, ADM, RM + TM 50/50, RM + TM 75/25, RM 100%). Group performance-intensity functions were computed for each listening condition to show the effects of microphone configuration with respect to signal-to-noise ratio (SNR). A difference score (CI Group minus NH Group) was computed to show the effect of microphone technology at different SNRs relative to NH. Statistical analysis using a repeated-measures analysis of variance evaluated the effects of the microphone configurations on SRT80% and performance at SNRs. Between-groups analysis of variance was used to compare the CI group with the NH group.
RESULTS: The speech recognition was significantly poorer for children with CI than children with NH in quiet and in noise when using the TM alone. Adding the ADM or RM provided a significant improvement in speech recognition for the CI group over use of the TM alone in noise (mean dB advantage ranged from 5.8 for ADM to 16 for RM100). When children with CI used the RM75 or RM100 in background babble, speech recognition was not statistically different from the group with NH.
CONCLUSION: Speech recognition in noise performance improved with the use of ADM and RM100 or RM75 over TM-only for children with CIs. Alhough children with CI remain at a disadvantage as compared with NH children in quiet and more favorable SNRs, microphone technology can enhance performance for some children with CI to match that of NH peers in contexts with negative SNRs.

PMID: 30278866 [PubMed - in process]



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Upgrade to Nucleus® 6 in Previous Generation Cochlear™ Sound Processor Recipients.

Related Articles

Upgrade to Nucleus® 6 in Previous Generation Cochlear™ Sound Processor Recipients.

J Am Acad Audiol. 2018 Oct;29(9):802-813

Authors: Biever A, Gilden J, Zwolan T, Mears M, Beiter A

Abstract
BACKGROUND: The Nucleus® 6 sound processor is now compatible with the Nucleus® 22 (CI22M)-Cochlear's first generation cochlear implant. The Nucleus 6 offers three new signal processing algorithms that purportedly facilitate improved hearing in background noise.
PURPOSE: These studies were designed to evaluate listening performance and user satisfaction with the Nucleus 6 sound processor.
RESEARCH DESIGN: The research design was a prospective, single-participant, repeated measures design.
STUDY SAMPLE: A group of 80 participants implanted with various Nucleus internal implant devices (CI22M, CI24M, Freedom® CI24RE, CI422, and CI512) were recruited from a total of six North American sites.
DATA COLLECTION AND ANALYSIS: Participants had their external sound processor upgraded to the Nucleus 6 sound processor. Final speech perception testing in noise and subjective questionnaires were completed after four or 12 weeks of take-home use with the Nucleus 6.
RESULTS: Speech perception testing in noise showed significant improvement and participants reported increased satisfaction with the Nucleus 6.
CONCLUSION: These studies demonstrated the benefit of the new algorithms in the Nucleus 6 over previous generations of sound processors.

PMID: 30278865 [PubMed - in process]



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The Effect of Increased Cognitive Demand on Auditory Processing Assessment.

Related Articles

The Effect of Increased Cognitive Demand on Auditory Processing Assessment.

J Am Acad Audiol. 2018 Oct;29(9):788-801

Authors: Hamlyn K, Welldon K, Clark B, van Steenbrugge W, Kapadia S

Abstract
BACKGROUND: Auditory processing (AP) is commonly regarded as the perceptual processing of auditory information in the central nervous system. However, the degree to which higher level cognitive processes are involved in AP or its disorders is contentious. Furthermore, there is little evidence regarding the effects of nonauditory cognitive processes on the various tests of AP in common clinical usage and thus on clinical diagnoses of auditory processing disorder.
PURPOSE: To determine the effects of increased cognitive demand, generated by using a dual-task paradigm, on performance on different AP tests and types of AP tests in common clinical usage. In addition, to investigate the relationship between executive function and changes in AP test performance associated with increased cognitive demand.
RESEARCH DESIGN: Counterbalanced repeated measures design, with assessment of AP test performance both on its own and in a dual-task paradigm designed to increase cognitive demand.
STUDY SAMPLE: Twenty-nine young adults, with no reported hearing, learning, language or attention difficulties, English as first language, and hearing and middle-ear status within normal limits.
DATA COLLECTION AND ANALYSIS: Testing was completed within a single 90-min session. A selection of standard AP tests, representing both adaptive and nonadaptive tests, as well as tests employing difference scores, was administered. These were Competing Sentences Test, Dichotic Digits Test, Frequency Pattern Test (nonadaptive tests); and Listening in Spatialized Noise-Sentences test, conditions "same-voice, 0°", "different-voice, 0°", and "same-voice, 90°" (adaptive tests), from which the difference scores "talker advantage" and "spatial advantage" were also derived. Each AP test was completed on its own (alone condition), and simultaneously with a visually presented task (dual-task condition). Executive function was assessed using the phonemic subtest of the Verbal Fluency Test. Nonparametric statistical test procedures were used.
RESULTS: All five AP measures obtained from the nonadaptive tests showed a significant performance decrement in the dual-task condition compared with the alone condition, with one exception because of a strong ceiling effect. By contrast, none of the three AP measures obtained from the adaptive tests showed a significant performance decrement in the dual-task condition. Furthermore, neither of the two AP measures based on difference scores showed a significant performance decrement, but this finding simply reflects the lack of significant decrements in the relevant raw scores. Consistent with past reports of associations between executive function and AP performance, a significant positive correlation was found between executive function scores and performance on the Dichotic Digits Test. However, there were no significant correlations between executive function scores and changes in AP test scores between alone and dual-task conditions.
CONCLUSIONS: Performance on commonly used nonadaptive tests of AP was significantly compromised by the increased cognitive demand resulting from the dual-task paradigm. By contrast, performance on AP measures obtained by adaptive test procedures was not significantly affected. Further investigation of the resilience to increased cognitive demand of the adaptive tests used here, and other adaptive tests of AP, is warranted. Results from this study support the further development of computerized adaptive tests of AP for use in clinical test batteries.

PMID: 30278864 [PubMed - in process]



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Acknowledging Those Who Have Contributed Significantly to Our Profession: The Academy Honors.

Related Articles

Acknowledging Those Who Have Contributed Significantly to Our Profession: The Academy Honors.

J Am Acad Audiol. 2018 Oct;29(9):786-787

Authors: Gaffney P, McCaslin DL

PMID: 30278863 [PubMed - in process]



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The Middle Latency Response: A Review of Findings in Various Central Nervous System Lesions.

Related Articles

The Middle Latency Response: A Review of Findings in Various Central Nervous System Lesions.

J Am Acad Audiol. 2018 Oct;29(9):855-867

Authors: Musiek F, Nagle S

Abstract
BACKGROUND: The middle latency response (MLR) first came to light as an auditory evoked potential in 1958. Since then, it has aroused substantial interest and investigation by clinicians and researchers alike. In recent history, its use and popularity have dwindled in tandem with various other auditory evoked potentials in audiology. One area for which MLR research and application has been overlooked is its potential value in measuring the neural integrity of the auditory thalamocortical pathway. In a broader sense, the MLR, when combined with the auditory brain stem response, can provide information concerning the status of much of the central auditory system pathways. This review is intended to provide information concerning the MLR as a measure of central auditory function for the reader to consider.
PURPOSE: To review and synthesize the scientific literature regarding the potential value of the MLR in assessing the integrity of the central auditory system and to provide the reader an informed perspective on the value of the MLR in this regard. Information is also provided on the MLR generator sites and fundamental characteristics of this evoked potential essential to its clinical and or research application.
RESEARCH DESIGN: A systematic review and synthesis of the literature focusing on the MLR and lesions of the central auditory system.
STUDY SAMPLE: Studies and individual cases were reviewed and analyzed that evidenced documented lesions of the central auditory nervous system.
DATA COLLECTION AND ANALYSIS: The authors searched and reviewed the literature (journal articles, book chapters, and books) pertaining to central auditory system lesion effects on the MLR.
RESULTS: Although findings varied from study to study, overall, the MLR was reasonably sensitive and specific to neurological compromise of the central auditory system. This finding is consistent with the generator sites of this evoked potential.
CONCLUSIONS: The MLR is a valuable tool for assessing the integrity of the central auditory system. It should be of interest to the clinician or researcher who focuses their attention on the function and dysfunction of the higher auditory system.

PMID: 30278870 [PubMed - in process]



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Refining Stimulus Parameters in Assessing Infant Speech Perception Using Visual Reinforcement Infant Speech Discrimination in Infants with and without Hearing Loss: Presentation Level.

Related Articles

Refining Stimulus Parameters in Assessing Infant Speech Perception Using Visual Reinforcement Infant Speech Discrimination in Infants with and without Hearing Loss: Presentation Level.

J Am Acad Audiol. 2018 Oct;29(9):847-854

Authors: Uhler KM, Gifford RH, Forster JE, Anderson M, Tierney E, Claycomb SD, Werner LA

PMID: 30278869 [PubMed - in process]



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Impact of Consistency in Daily Device Use on Speech Perception Abilities in Children with Cochlear Implants: Datalogging Evidence.

Related Articles

Impact of Consistency in Daily Device Use on Speech Perception Abilities in Children with Cochlear Implants: Datalogging Evidence.

J Am Acad Audiol. 2018 Oct;29(9):835-846

Authors: Easwar V, Sanfilippo J, Papsin B, Gordon K

Abstract
BACKGROUND: Cochlear implants (CIs) give children with severe to profound hearing loss access to sound. There appears to be a dose effect of sound exposure on speech perception abilities as shown by the positive influence of early implantation and CI experience. The consistency in device use per day could also affect sound dose, potentially affecting perceptual abilities in children with CIs.
PURPOSE: The objectives of the present study were to identify the impact of consistency in device use on: (1) speech perception abilities and (2) asymmetry in speech perception abilities between bilateral CIs.
RESEARCH DESIGN: Retrospective analysis.
STUDY SAMPLE: To achieve the first objective, data from 65 children (age range at speech test: 1.91-18.05 yrs) with one (unilaterally implanted or bimodal) or two CIs (sequentially or simultaneously implanted) were included. A subset of data from 40 children with bilateral CIs was included to achieve the second objective. Of the 40 children with two CIs, 15 received their CIs sequentially.
DATA COLLECTION AND ANALYSIS: Device use information was extracted from datalogs stored in personal speech processors using custom software. Speech perception scores per CI collected in quiet were also evaluated. Multiple regression was used to assess the impact of daily CI use, while controlling for factors previously identified to affect speech perception: age at speech test, length of pre-CI (acoustic) hearing experience, length of CI hearing experience, and order of CI for the first objective, and CI category (simultaneous/sequential implantation), interimplant delay, and length of CI experience for the second objective.
RESULTS: On average, children wore their CIs for 11.59 ± 2.86 hours/day and, with one CI, exhibited 65.07 ± 22.64% accuracy on speech perception tests. Higher monaural speech perception scores were associated with longer everyday CI use and CI experience (p < 0.05). Among children with bilateral CIs, those with simultaneously implanted CIs and similar bilateral hearing experience demonstrated a small but significant right ear advantage with higher speech perception scores when using the right rather than left CI (mean difference = 4.55 ± 9.83%). The asymmetry in speech perception between CIs was larger and more variable in children who received their CIs sequentially (mean difference CI1-CI2 = 27.48 ± 24.87%). These asymmetries decreased with longer/consistent everyday use of the newer CI (p < 0.05). Yet, despite consistent everyday device use of the second CI (>12 hours/day), only a small proportion of children implanted sequentially (one out of seven children) achieved symmetrical function similar to children with simultaneously received bilateral CIs.
CONCLUSIONS: Consistent everyday CI use contributes to higher speech perception scores. Although consistent CI use can help reduce the asymmetry in speech perception abilities of children with sequentially implanted CIs subsequent to interimplant delay, residual asymmetry often persists.

PMID: 30278868 [PubMed - in process]



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Accounting for the Occlusion Effect with Insert Earphones.

Related Articles

Accounting for the Occlusion Effect with Insert Earphones.

J Am Acad Audiol. 2018 Oct;29(9):826-834

Authors: Neave-DiToro D, DeSantolo A, Bergen M, Rubinstein A

Abstract
BACKGROUND: There are clinical implications associated with knowing when the occlusion effect (OE) must be accounted for during bone conduction (BC) testing because spurious results can occur when errors are made in this regard. The amount of OE produced when insert earphones (IEs) are used varies in the literature; thus, further investigation is warranted.
PURPOSE: The purpose of this project was to determine the OE during BC threshold measurements under the following occluding conditions used clinically: when using partial insertion (PI) versus full insertion (FI) depth and when occluding one versus both ears.
RESEARCH DESIGN: A descriptive within-subjects design was used in this study.
STUDY SAMPLE: Twenty-two adults with mean four-frequency pure tone averages of 24 dB HL, aged 40-83 yr, participated.
INTERVENTION: BC thresholds were obtained at 250, 500, and 1000 Hz under seven conditions: (1) both ears unoccluded, (2) left ear occluded with PI, (3) right ear occluded with PI, (4) both ears occluded with PI, (5) left ear occluded with FI, (6) right ear occluded with FI, (7) both ears occluded with FI. For PI, one half of the length of the IE was beyond the opening of the ear canal. For FI, the lateral edge of the foam insert was flush with the entrance to the ear canal.
DATA COLLECTION AND ANALYSIS: Mean OEs were compared with previously published data. In addition, variability in the data was examined using frequency distribution plots as well as cumulative frequency and percentile values.
RESULTS: Mean OEs of 5-13 dB were present in all but the FI condition at 1000 Hz where the OE was <3 dB. Differences between PI and FI conditions were present at each frequency measured, irrespective of whether one or both ears were occluded. The shifts in threshold were consistently more prevalent and greater for the PI than the FI conditions overall. Mean differences between the one-ear and both-ears conditions were not clinically significant. Clinically significant variability in the data was noted, except when comparing the one-ear versus both-ears conditions.
CONCLUSIONS: Occluding the ear during initial BC measurements may artificially improve the thresholds and create or exaggerate an air-bone gap. Thus, initial BC testing should be performed unoccluded at 250, 500, and 1000 Hz. There is a need to account for the OE even when the IE is flush with the ear canal to avoid insufficient masking.

PMID: 30278867 [PubMed - in process]



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Using Microphone Technology to Improve Speech Perception in Noise in Children with Cochlear Implants.

Related Articles

Using Microphone Technology to Improve Speech Perception in Noise in Children with Cochlear Implants.

J Am Acad Audiol. 2018 Oct;29(9):814-825

Authors: Johnstone PM, Mills KET, Humphrey E, Yeager KR, Jones E, McElligott K, Pierce A, Agrawal S, Froeling C, Little JP

Abstract
BACKGROUND: Cochlear implant (CI) users are affected more than their normal hearing (NH) peers by the negative consequences of background noise on speech understanding. Research has shown that adult CI users can improve their speech recognition in challenging listening environments by using dual-microphone beamformers, such as adaptive directional microphones (ADMs) and wireless remote microphones (RMs). The suitability of these microphone technologies for use in children with CIs is not well-understood nor widely accepted.
PURPOSE: To assess the benefit of ADM or RM technology on speech perception in background noise in children and adolescents with cochlear implants (CIs) with no previous or current use of ADM or RM.
RESEARCH DESIGN: Mixed, repeated measures design.
STUDY SAMPLE: Twenty (20) children, ten (10) CI users (mean age 14.3 yrs) who used Advanced Bionics HiRes90K implants with research Naida processors, and ten (10) NH age-matched controls participated in this prospective study.
INTERVENTION: CI users listened with an ear-canal level microphone, T-Mic (TM), an ADM, and a wireless RM at different audio-mixing ratios. Speech understanding with five microphone settings (TM 100%, ADM, RM + TM 50/50, RM + TM 75/25, RM 100%) was evaluated in quiet and in noise.
DATA COLLECTION AND ANALYSIS: Speech perception ability was measured using children's spondee words to obtain a speech recognition threshold for 80% accuracy (SRT80%) in 20-talker babble where the listener sat in a sound booth 1 m (3.28') from the target speech (front) and noise (behind) to test five microphone settings (TM 100%, ADM, RM + TM 50/50, RM + TM 75/25, RM 100%). Group performance-intensity functions were computed for each listening condition to show the effects of microphone configuration with respect to signal-to-noise ratio (SNR). A difference score (CI Group minus NH Group) was computed to show the effect of microphone technology at different SNRs relative to NH. Statistical analysis using a repeated-measures analysis of variance evaluated the effects of the microphone configurations on SRT80% and performance at SNRs. Between-groups analysis of variance was used to compare the CI group with the NH group.
RESULTS: The speech recognition was significantly poorer for children with CI than children with NH in quiet and in noise when using the TM alone. Adding the ADM or RM provided a significant improvement in speech recognition for the CI group over use of the TM alone in noise (mean dB advantage ranged from 5.8 for ADM to 16 for RM100). When children with CI used the RM75 or RM100 in background babble, speech recognition was not statistically different from the group with NH.
CONCLUSION: Speech recognition in noise performance improved with the use of ADM and RM100 or RM75 over TM-only for children with CIs. Alhough children with CI remain at a disadvantage as compared with NH children in quiet and more favorable SNRs, microphone technology can enhance performance for some children with CI to match that of NH peers in contexts with negative SNRs.

PMID: 30278866 [PubMed - in process]



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Upgrade to Nucleus® 6 in Previous Generation Cochlear™ Sound Processor Recipients.

Related Articles

Upgrade to Nucleus® 6 in Previous Generation Cochlear™ Sound Processor Recipients.

J Am Acad Audiol. 2018 Oct;29(9):802-813

Authors: Biever A, Gilden J, Zwolan T, Mears M, Beiter A

Abstract
BACKGROUND: The Nucleus® 6 sound processor is now compatible with the Nucleus® 22 (CI22M)-Cochlear's first generation cochlear implant. The Nucleus 6 offers three new signal processing algorithms that purportedly facilitate improved hearing in background noise.
PURPOSE: These studies were designed to evaluate listening performance and user satisfaction with the Nucleus 6 sound processor.
RESEARCH DESIGN: The research design was a prospective, single-participant, repeated measures design.
STUDY SAMPLE: A group of 80 participants implanted with various Nucleus internal implant devices (CI22M, CI24M, Freedom® CI24RE, CI422, and CI512) were recruited from a total of six North American sites.
DATA COLLECTION AND ANALYSIS: Participants had their external sound processor upgraded to the Nucleus 6 sound processor. Final speech perception testing in noise and subjective questionnaires were completed after four or 12 weeks of take-home use with the Nucleus 6.
RESULTS: Speech perception testing in noise showed significant improvement and participants reported increased satisfaction with the Nucleus 6.
CONCLUSION: These studies demonstrated the benefit of the new algorithms in the Nucleus 6 over previous generations of sound processors.

PMID: 30278865 [PubMed - in process]



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The Effect of Increased Cognitive Demand on Auditory Processing Assessment.

Related Articles

The Effect of Increased Cognitive Demand on Auditory Processing Assessment.

J Am Acad Audiol. 2018 Oct;29(9):788-801

Authors: Hamlyn K, Welldon K, Clark B, van Steenbrugge W, Kapadia S

Abstract
BACKGROUND: Auditory processing (AP) is commonly regarded as the perceptual processing of auditory information in the central nervous system. However, the degree to which higher level cognitive processes are involved in AP or its disorders is contentious. Furthermore, there is little evidence regarding the effects of nonauditory cognitive processes on the various tests of AP in common clinical usage and thus on clinical diagnoses of auditory processing disorder.
PURPOSE: To determine the effects of increased cognitive demand, generated by using a dual-task paradigm, on performance on different AP tests and types of AP tests in common clinical usage. In addition, to investigate the relationship between executive function and changes in AP test performance associated with increased cognitive demand.
RESEARCH DESIGN: Counterbalanced repeated measures design, with assessment of AP test performance both on its own and in a dual-task paradigm designed to increase cognitive demand.
STUDY SAMPLE: Twenty-nine young adults, with no reported hearing, learning, language or attention difficulties, English as first language, and hearing and middle-ear status within normal limits.
DATA COLLECTION AND ANALYSIS: Testing was completed within a single 90-min session. A selection of standard AP tests, representing both adaptive and nonadaptive tests, as well as tests employing difference scores, was administered. These were Competing Sentences Test, Dichotic Digits Test, Frequency Pattern Test (nonadaptive tests); and Listening in Spatialized Noise-Sentences test, conditions "same-voice, 0°", "different-voice, 0°", and "same-voice, 90°" (adaptive tests), from which the difference scores "talker advantage" and "spatial advantage" were also derived. Each AP test was completed on its own (alone condition), and simultaneously with a visually presented task (dual-task condition). Executive function was assessed using the phonemic subtest of the Verbal Fluency Test. Nonparametric statistical test procedures were used.
RESULTS: All five AP measures obtained from the nonadaptive tests showed a significant performance decrement in the dual-task condition compared with the alone condition, with one exception because of a strong ceiling effect. By contrast, none of the three AP measures obtained from the adaptive tests showed a significant performance decrement in the dual-task condition. Furthermore, neither of the two AP measures based on difference scores showed a significant performance decrement, but this finding simply reflects the lack of significant decrements in the relevant raw scores. Consistent with past reports of associations between executive function and AP performance, a significant positive correlation was found between executive function scores and performance on the Dichotic Digits Test. However, there were no significant correlations between executive function scores and changes in AP test scores between alone and dual-task conditions.
CONCLUSIONS: Performance on commonly used nonadaptive tests of AP was significantly compromised by the increased cognitive demand resulting from the dual-task paradigm. By contrast, performance on AP measures obtained by adaptive test procedures was not significantly affected. Further investigation of the resilience to increased cognitive demand of the adaptive tests used here, and other adaptive tests of AP, is warranted. Results from this study support the further development of computerized adaptive tests of AP for use in clinical test batteries.

PMID: 30278864 [PubMed - in process]



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Acknowledging Those Who Have Contributed Significantly to Our Profession: The Academy Honors.

Related Articles

Acknowledging Those Who Have Contributed Significantly to Our Profession: The Academy Honors.

J Am Acad Audiol. 2018 Oct;29(9):786-787

Authors: Gaffney P, McCaslin DL

PMID: 30278863 [PubMed - in process]



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Postural Stability in Goalkeepers of the Polish National Junior Handball Team.

Related Articles

Postural Stability in Goalkeepers of the Polish National Junior Handball Team.

J Hum Kinet. 2018 Aug 31;63:161-170

Authors: Wilczyński J

Abstract
The aim of the study was to assess postural stability of goalkeepers from the Polish national junior handball team. Eleven juniors of the Polish national handball team (age 16.82 ± 1.6 years, body height 191.27 ± 3.1 cm, body mass 88.41 ± 12.26 kg, BMI 24.18 ± 3.22 kg/m2) were selected for the study. The Biodex Balance System and AccuGait AM¬TI platform were used to evaluate postural stability. The obtained results indicated good postural stability of the subjects. During the Biodex Balance System platform tests, all subjects presented very good postural stability and maintained within Zone A. Postural sway was greater in the sagittal plane compared to the frontal one. Most of the participants demonstrated slight backward tilts, but maintained in Quadrant IV. During the AccuGait AMTI platform trial, Path Length and Average COP Speed significantly increased in the test performed with closed eyes. Furthermore, there were significant positive correlations between the number of variables obtained during the Biodex Balance System and AccuGait AMTI tests. Proper and stable posture are necessary conditions to be met to carry out most free movements and locomotion. They play a significant role in the game of a handball goalkeeper and for that reason, postural stability testing of handball goalkeepers is an important element of coordination training. Thus, the use of postural stability exercises implementing the biofeedback method on stabilo and dynamometric platforms is practical and justifiable.

PMID: 30279951 [PubMed]



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Postural Stability in Goalkeepers of the Polish National Junior Handball Team.

Related Articles

Postural Stability in Goalkeepers of the Polish National Junior Handball Team.

J Hum Kinet. 2018 Aug 31;63:161-170

Authors: Wilczyński J

Abstract
The aim of the study was to assess postural stability of goalkeepers from the Polish national junior handball team. Eleven juniors of the Polish national handball team (age 16.82 ± 1.6 years, body height 191.27 ± 3.1 cm, body mass 88.41 ± 12.26 kg, BMI 24.18 ± 3.22 kg/m2) were selected for the study. The Biodex Balance System and AccuGait AM¬TI platform were used to evaluate postural stability. The obtained results indicated good postural stability of the subjects. During the Biodex Balance System platform tests, all subjects presented very good postural stability and maintained within Zone A. Postural sway was greater in the sagittal plane compared to the frontal one. Most of the participants demonstrated slight backward tilts, but maintained in Quadrant IV. During the AccuGait AMTI platform trial, Path Length and Average COP Speed significantly increased in the test performed with closed eyes. Furthermore, there were significant positive correlations between the number of variables obtained during the Biodex Balance System and AccuGait AMTI tests. Proper and stable posture are necessary conditions to be met to carry out most free movements and locomotion. They play a significant role in the game of a handball goalkeeper and for that reason, postural stability testing of handball goalkeepers is an important element of coordination training. Thus, the use of postural stability exercises implementing the biofeedback method on stabilo and dynamometric platforms is practical and justifiable.

PMID: 30279951 [PubMed]



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