Objectives: The normal process of aging is mostly associated with global decline in almost all sensory aspects of the human body. While aging affects the 500-Hz tone burst-evoked ocular vestibular-evoked myogenic potentials (oVEMPs) by reducing the amplitudes and prolonging the latencies, its interaction with oVEMP responses at other frequencies has not been studied. Therefore, the present study aimed at investigating the impact of advancing age on the frequency tuning of oVEMP. Design: Using a cross-sectional research design, oVEMPs were recorded for tone burst frequencies of 250, 500, 750, 1000, 1500, and 2000 Hz from 270 healthy individuals divided into six age groups (10-20, 20-30, 30-40, 40-50, 50-60, and >60 years). Results: The results revealed significantly lower response rates and amplitudes in age groups above 50 years of age than all the other groups at nearly all the frequencies (p =1000 Hz in most of the individuals above 60 years of age (p =1000 Hz in older adults, especially above 60 years of age. Conclusions: The results of the study showed significantly higher prevalence of frequency tuning at 1000 Hz in older adults above 60 years of age. Because the shift in frequency tuning to >=1000 Hz is frequently used for identification of Meniere's disease, it is suggested that age-related correction be used for the diagnosis of Meniere's disease when using frequency tuning of oVEMP. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
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Τρίτη 22 Αυγούστου 2017
Characterizing the Age and Stimulus Frequency Interaction for Ocular Vestibular-Evoked Myogenic Potentials.
Objectives: The normal process of aging is mostly associated with global decline in almost all sensory aspects of the human body. While aging affects the 500-Hz tone burst-evoked ocular vestibular-evoked myogenic potentials (oVEMPs) by reducing the amplitudes and prolonging the latencies, its interaction with oVEMP responses at other frequencies has not been studied. Therefore, the present study aimed at investigating the impact of advancing age on the frequency tuning of oVEMP. Design: Using a cross-sectional research design, oVEMPs were recorded for tone burst frequencies of 250, 500, 750, 1000, 1500, and 2000 Hz from 270 healthy individuals divided into six age groups (10-20, 20-30, 30-40, 40-50, 50-60, and >60 years). Results: The results revealed significantly lower response rates and amplitudes in age groups above 50 years of age than all the other groups at nearly all the frequencies (p =1000 Hz in most of the individuals above 60 years of age (p =1000 Hz in older adults, especially above 60 years of age. Conclusions: The results of the study showed significantly higher prevalence of frequency tuning at 1000 Hz in older adults above 60 years of age. Because the shift in frequency tuning to >=1000 Hz is frequently used for identification of Meniere's disease, it is suggested that age-related correction be used for the diagnosis of Meniere's disease when using frequency tuning of oVEMP. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
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Characterizing the Age and Stimulus Frequency Interaction for Ocular Vestibular-Evoked Myogenic Potentials.
Objectives: The normal process of aging is mostly associated with global decline in almost all sensory aspects of the human body. While aging affects the 500-Hz tone burst-evoked ocular vestibular-evoked myogenic potentials (oVEMPs) by reducing the amplitudes and prolonging the latencies, its interaction with oVEMP responses at other frequencies has not been studied. Therefore, the present study aimed at investigating the impact of advancing age on the frequency tuning of oVEMP. Design: Using a cross-sectional research design, oVEMPs were recorded for tone burst frequencies of 250, 500, 750, 1000, 1500, and 2000 Hz from 270 healthy individuals divided into six age groups (10-20, 20-30, 30-40, 40-50, 50-60, and >60 years). Results: The results revealed significantly lower response rates and amplitudes in age groups above 50 years of age than all the other groups at nearly all the frequencies (p =1000 Hz in most of the individuals above 60 years of age (p =1000 Hz in older adults, especially above 60 years of age. Conclusions: The results of the study showed significantly higher prevalence of frequency tuning at 1000 Hz in older adults above 60 years of age. Because the shift in frequency tuning to >=1000 Hz is frequently used for identification of Meniere's disease, it is suggested that age-related correction be used for the diagnosis of Meniere's disease when using frequency tuning of oVEMP. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.
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Pioneering Review Compares State-Level Hearing Aid Coverage
Researchers at the University of South Florida conducted the first-ever comprehensive review of state Medicaid hearing aid coverage for older adults. The study was published in the August edition of Health Affairs entitled "Medicaid Hearing Aid Coverage for Older Adult Beneficiaries: A State-by-State Comparison."
While more than 26 million older adults in the United States have hearing loss, only about 25 percent of those with moderate to severe hearing loss use hearing aids, and the percentage may be even lower in those with mild to moderate hearing loss. The study's lead author, Michelle Arnold, AuD, highlighted the significance of the issue: "Lack of hearing aid uptake is a public health concern, as untreated age-related hearing loss, with its concomitant reductions in speech understanding is associated with increased risks of social isolation, falls, hospitalizations and cognitive decline and with a disease burden of up to four disability-adjusted life years."
The researchers found that 22 states do not provide Medicaid hearing aid coverage at all since coverage is not federally mandated. Of the states that do provide coverage, the extent varies widely.
The study used six criteria to rank the states' Medicaid coverage policies, including eligibility of assessment and treatment, two hearing aids, batteries, supplies, follow-up rehabilitation, and repairs or replacement.
The researchers conclude the study by urging that "federal policy makers should consider making hearing health care, including the coverage of hearing aids, mandated under Medicaid."
Published: 8/22/2017 3:59:00 PM
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Early Intervention Improves Vocabulary of Hearing- Impaired Children
A recent study conducted at the Institute of Cognitive Science (ICS) at the University of Colorado found that infants born with hearing loss who are identified and treated according to the Early Hearing Detection and Intervention (EHDI) guidelines have markedly better vocabulary outcomes than those who are not. This is the first multi-state study to examine the effectiveness of all three stages of EHDI on vocabulary outcomes.
The study analyzed 448 children (between the ages of 8 to 39 months) with hearing loss participating in the National Early Childhood Assessment Project in 12 states. Fifty-eight percent of the study participants were found to meet the EHDI 1-3-6 guidelines.
The EHDI 1-3-6 guidelines include a hearing loss screening within one month of age, a diagnosis of hearing loss by a specialist within three months of age, and an intervention by six months.
Of the participants who were treated within six months, their Vocabulary Quotients (VQs) had a mean of 82, while 64 percent of those who did not meet EHDI guidelines but had no additional disabilities had a score less than 75 (100 is the norm).
According to Christine Yoshinaga-Itano, PhD, audiologist and researcher at ICS, children who do not receive early intervention in accordance with the EHDI timeframe are considered to have what amounts to an "environmentally induced and preventable secondary disability" and observed to function like children with cognitive delay.
The researchers concluded that future systemic improvement of vocabulary learning will need to focus on "preventing widening delays with chronological age, assisting mothers with lower levels of education, and incorporating adults who are deaf/hard of hearing in the intervention process."
Published: 8/22/2017 8:28:00 AM
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Pioneering Review Compares State-Level Hearing Aid Coverage
Researchers at the University of South Florida conducted the first-ever comprehensive review of state Medicaid hearing aid coverage for older adults. The study was published in the August edition of Health Affairs entitled "Medicaid Hearing Aid Coverage for Older Adult Beneficiaries: A State-by-State Comparison."
While more than 26 million older adults in the United States have hearing loss, only about 25 percent of those with moderate to severe hearing loss use hearing aids, and the percentage may be even lower in those with mild to moderate hearing loss. The study's lead author, Michelle Arnold, AuD, highlighted the significance of the issue: "Lack of hearing aid uptake is a public health concern, as untreated age-related hearing loss, with its concomitant reductions in speech understanding is associated with increased risks of social isolation, falls, hospitalizations and cognitive decline and with a disease burden of up to four disability-adjusted life years."
The researchers found that 22 states do not provide Medicaid hearing aid coverage at all since coverage is not federally mandated. Of the states that do provide coverage, the extent varies widely.
The study used six criteria to rank the states' Medicaid coverage policies, including eligibility of assessment and treatment, two hearing aids, batteries, supplies, follow-up rehabilitation, and repairs or replacement.
The researchers conclude the study by urging that "federal policy makers should consider making hearing health care, including the coverage of hearing aids, mandated under Medicaid."
Published: 8/22/2017 3:59:00 PM
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Early Intervention Improves Vocabulary of Hearing- Impaired Children
A recent study conducted at the Institute of Cognitive Science (ICS) at the University of Colorado found that infants born with hearing loss who are identified and treated according to the Early Hearing Detection and Intervention (EHDI) guidelines have markedly better vocabulary outcomes than those who are not. This is the first multi-state study to examine the effectiveness of all three stages of EHDI on vocabulary outcomes.
The study analyzed 448 children (between the ages of 8 to 39 months) with hearing loss participating in the National Early Childhood Assessment Project in 12 states. Fifty-eight percent of the study participants were found to meet the EHDI 1-3-6 guidelines.
The EHDI 1-3-6 guidelines include a hearing loss screening within one month of age, a diagnosis of hearing loss by a specialist within three months of age, and an intervention by six months.
Of the participants who were treated within six months, their Vocabulary Quotients (VQs) had a mean of 82, while 64 percent of those who did not meet EHDI guidelines but had no additional disabilities had a score less than 75 (100 is the norm).
According to Christine Yoshinaga-Itano, PhD, audiologist and researcher at ICS, children who do not receive early intervention in accordance with the EHDI timeframe are considered to have what amounts to an "environmentally induced and preventable secondary disability" and observed to function like children with cognitive delay.
The researchers concluded that future systemic improvement of vocabulary learning will need to focus on "preventing widening delays with chronological age, assisting mothers with lower levels of education, and incorporating adults who are deaf/hard of hearing in the intervention process."
Published: 8/22/2017 8:28:00 AM
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Pioneering Review Compares State-Level Hearing Aid Coverage
Researchers at the University of South Florida conducted the first-ever comprehensive review of state Medicaid hearing aid coverage for older adults. The study was published in the August edition of Health Affairs entitled "Medicaid Hearing Aid Coverage for Older Adult Beneficiaries: A State-by-State Comparison."
While more than 26 million older adults in the United States have hearing loss, only about 25 percent of those with moderate to severe hearing loss use hearing aids, and the percentage may be even lower in those with mild to moderate hearing loss. The study's lead author, Michelle Arnold, AuD, highlighted the significance of the issue: "Lack of hearing aid uptake is a public health concern, as untreated age-related hearing loss, with its concomitant reductions in speech understanding is associated with increased risks of social isolation, falls, hospitalizations and cognitive decline and with a disease burden of up to four disability-adjusted life years."
The researchers found that 22 states do not provide Medicaid hearing aid coverage at all since coverage is not federally mandated. Of the states that do provide coverage, the extent varies widely.
The study used six criteria to rank the states' Medicaid coverage policies, including eligibility of assessment and treatment, two hearing aids, batteries, supplies, follow-up rehabilitation, and repairs or replacement.
The researchers conclude the study by urging that "federal policy makers should consider making hearing health care, including the coverage of hearing aids, mandated under Medicaid."
Published: 8/22/2017 3:59:00 PM
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Early Intervention Improves Vocabulary of Hearing- Impaired Children
A recent study conducted at the Institute of Cognitive Science (ICS) at the University of Colorado found that infants born with hearing loss who are identified and treated according to the Early Hearing Detection and Intervention (EHDI) guidelines have markedly better vocabulary outcomes than those who are not. This is the first multi-state study to examine the effectiveness of all three stages of EHDI on vocabulary outcomes.
The study analyzed 448 children (between the ages of 8 to 39 months) with hearing loss participating in the National Early Childhood Assessment Project in 12 states. Fifty-eight percent of the study participants were found to meet the EHDI 1-3-6 guidelines.
The EHDI 1-3-6 guidelines include a hearing loss screening within one month of age, a diagnosis of hearing loss by a specialist within three months of age, and an intervention by six months.
Of the participants who were treated within six months, their Vocabulary Quotients (VQs) had a mean of 82, while 64 percent of those who did not meet EHDI guidelines but had no additional disabilities had a score less than 75 (100 is the norm).
According to Christine Yoshinaga-Itano, PhD, audiologist and researcher at ICS, children who do not receive early intervention in accordance with the EHDI timeframe are considered to have what amounts to an "environmentally induced and preventable secondary disability" and observed to function like children with cognitive delay.
The researchers concluded that future systemic improvement of vocabulary learning will need to focus on "preventing widening delays with chronological age, assisting mothers with lower levels of education, and incorporating adults who are deaf/hard of hearing in the intervention process."
Published: 8/22/2017 8:28:00 AM
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Welcome MA Speech-Language Pathology class of 2019!
See our incoming Master of Arts students (class of 2019) at the first day of orientation taking a break to watch the solar eclipse on August 21, 2017:
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Welcome MA Speech-Language Pathology class of 2019!
See our incoming Master of Arts students (class of 2019) at the first day of orientation taking a break to watch the solar eclipse on August 21, 2017:
from #Audiology via ola Kala on Inoreader http://ift.tt/2imMLMi
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Welcome MA Speech-Language Pathology class of 2019!
See our incoming Master of Arts students (class of 2019) at the first day of orientation taking a break to watch the solar eclipse on August 21, 2017:
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2imMLMi
via IFTTT
Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration.
| Related Articles |
Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration.
Front Mol Neurosci. 2017;10:236
Authors: Mittal R, Nguyen D, Patel AP, Debs LH, Mittal J, Yan D, Eshraghi AA, Van De Water TR, Liu XZ
Abstract
Neurosensory responses of hearing and balance are mediated by receptors in specialized neuroepithelial sensory cells. Any disruption of the biochemical and molecular pathways that facilitate these responses can result in severe deficits, including hearing loss and vestibular dysfunction. Hearing is affected by both environmental and genetic factors, with impairment of auditory function being the most common neurosensory disorder affecting 1 in 500 newborns, as well as having an impact on the majority of elderly population. Damage to auditory sensory cells is not reversible, and if sufficient damage and cell death have taken place, the resultant deficit may lead to permanent deafness. Cochlear implants are considered to be one of the most successful and consistent treatments for deaf patients, but only offer limited recovery at the expense of loss of residual hearing. Recently there has been an increased interest in the auditory research community to explore the regeneration of mammalian auditory hair cells and restoration of their function. In this review article, we examine a variety of recent therapies, including genetic, stem cell and molecular therapies as well as discussing progress being made in genome editing strategies as applied to the restoration of hearing function.
PMID: 28824370 [PubMed]
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Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration.
| Related Articles |
Recent Advancements in the Regeneration of Auditory Hair Cells and Hearing Restoration.
Front Mol Neurosci. 2017;10:236
Authors: Mittal R, Nguyen D, Patel AP, Debs LH, Mittal J, Yan D, Eshraghi AA, Van De Water TR, Liu XZ
Abstract
Neurosensory responses of hearing and balance are mediated by receptors in specialized neuroepithelial sensory cells. Any disruption of the biochemical and molecular pathways that facilitate these responses can result in severe deficits, including hearing loss and vestibular dysfunction. Hearing is affected by both environmental and genetic factors, with impairment of auditory function being the most common neurosensory disorder affecting 1 in 500 newborns, as well as having an impact on the majority of elderly population. Damage to auditory sensory cells is not reversible, and if sufficient damage and cell death have taken place, the resultant deficit may lead to permanent deafness. Cochlear implants are considered to be one of the most successful and consistent treatments for deaf patients, but only offer limited recovery at the expense of loss of residual hearing. Recently there has been an increased interest in the auditory research community to explore the regeneration of mammalian auditory hair cells and restoration of their function. In this review article, we examine a variety of recent therapies, including genetic, stem cell and molecular therapies as well as discussing progress being made in genome editing strategies as applied to the restoration of hearing function.
PMID: 28824370 [PubMed]
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