Τετάρτη 5 Οκτωβρίου 2016
Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea
Source:Hearing Research
Author(s): Yoshinobu Hirose, Kazuma Sugahara, Eiju Kanagawa, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita
Eighteen supplement drugs were screened using hair cells to determine a protective effect against the adverse effects of neomycin by using the zebrafish lateral line. The zebrafish were administered the supplement drugs one hour before neomycin exposure. One hour later, animals were fixed in paraformaldehyde. Dose-response curves were generated to evaluate the protective effect on hair cells. The screen identified 3 supplements (quercetin, catechin and tannic acid).Three minutes after exposure to neomycin, increased antioxidant activity was found in the lateral line hair cells, as determined by the analysis of oxidative stress. Quercetin decreases antioxidant activity.The identified drugs were also investigated to determine whether they protect the cochlea against noise-induced hearing loss in guinea pigs. The drugs were administered via the intraperitoneal route in the guinea pigs 3 days before and 4 days after noise exposure. Seven days after noise exposure (130-dB sound pressure level for 3 hours), the auditory brainstem response threshold shifts were assessed. We observed that the auditory brainstem response threshold shift was significantly less in the quercetin group than in the vehicle control group. The results of our study indicate that screening drugs using zebrafish can determine additional protective drugs for the inner ear.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dLiV20
via IFTTT
Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea
Source:Hearing Research
Author(s): Yoshinobu Hirose, Kazuma Sugahara, Eiju Kanagawa, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita
Eighteen supplement drugs were screened using hair cells to determine a protective effect against the adverse effects of neomycin by using the zebrafish lateral line. The zebrafish were administered the supplement drugs one hour before neomycin exposure. One hour later, animals were fixed in paraformaldehyde. Dose-response curves were generated to evaluate the protective effect on hair cells. The screen identified 3 supplements (quercetin, catechin and tannic acid).Three minutes after exposure to neomycin, increased antioxidant activity was found in the lateral line hair cells, as determined by the analysis of oxidative stress. Quercetin decreases antioxidant activity.The identified drugs were also investigated to determine whether they protect the cochlea against noise-induced hearing loss in guinea pigs. The drugs were administered via the intraperitoneal route in the guinea pigs 3 days before and 4 days after noise exposure. Seven days after noise exposure (130-dB sound pressure level for 3 hours), the auditory brainstem response threshold shifts were assessed. We observed that the auditory brainstem response threshold shift was significantly less in the quercetin group than in the vehicle control group. The results of our study indicate that screening drugs using zebrafish can determine additional protective drugs for the inner ear.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2dLiV20
via IFTTT
Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea
Source:Hearing Research
Author(s): Yoshinobu Hirose, Kazuma Sugahara, Eiju Kanagawa, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita
Eighteen supplement drugs were screened using hair cells to determine a protective effect against the adverse effects of neomycin by using the zebrafish lateral line. The zebrafish were administered the supplement drugs one hour before neomycin exposure. One hour later, animals were fixed in paraformaldehyde. Dose-response curves were generated to evaluate the protective effect on hair cells. The screen identified 3 supplements (quercetin, catechin and tannic acid).Three minutes after exposure to neomycin, increased antioxidant activity was found in the lateral line hair cells, as determined by the analysis of oxidative stress. Quercetin decreases antioxidant activity.The identified drugs were also investigated to determine whether they protect the cochlea against noise-induced hearing loss in guinea pigs. The drugs were administered via the intraperitoneal route in the guinea pigs 3 days before and 4 days after noise exposure. Seven days after noise exposure (130-dB sound pressure level for 3 hours), the auditory brainstem response threshold shifts were assessed. We observed that the auditory brainstem response threshold shift was significantly less in the quercetin group than in the vehicle control group. The results of our study indicate that screening drugs using zebrafish can determine additional protective drugs for the inner ear.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dLiV20
via IFTTT
Improved Kinect-based Spatiotemporal and Kinematic Treadmill Gait Assessment
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Pilot Testing of a Variable Stiffness Transverse Plane Adapter for Lower Limb Amputees
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via ola Kala on Inoreader http://ift.tt/2cT6U4t
via IFTTT
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via ola Kala on Inoreader http://ift.tt/2cT6U4t
via IFTTT
A novel method for synchronizing motion capture with other data sources for millisecond-level precision
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Improved Kinect-based Spatiotemporal and Kinematic Treadmill Gait Assessment
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Pilot Testing of a Variable Stiffness Transverse Plane Adapter for Lower Limb Amputees
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cT6U4t
via IFTTT
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2cT6U4t
via IFTTT
A novel method for synchronizing motion capture with other data sources for millisecond-level precision
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Improved Kinect-based Spatiotemporal and Kinematic Treadmill Gait Assessment
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Source:Gait & Posture
Author(s): Moataz Eltoukhy, Jeonghoon Oh, Christopher Kuenze, Joseph Signorile
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhb9x
via IFTTT
Pilot Testing of a Variable Stiffness Transverse Plane Adapter for Lower Limb Amputees
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via ola Kala on Inoreader http://ift.tt/2cT6U4t
via IFTTT
Source:Gait & Posture
Author(s): Corey Pew, Glenn K. Klute
Amputees often experience soft tissue breakdown and discomfort from the high transverse plane shear stresses between the residual limb and prosthesis. To evaluate the effects of varying the transverse plane stiffness, a small sample population of lower limb amputees wore a novel variable stiffness torsion adapter (VSTA). Peak transverse plane moments were evaluated for three fixed stiffness levels (compliant: 0.30Nm/°, intermediate: 0.57Nm/°, stiff: 0.91Nm/°) while participants traversed five tasks of daily living that emphasize transverse plane motion including: straight walking for reference, 90° turns, 180° turns, a static reach test, and the L-Test of functional mobility. Results indicated that activities requiring high levels of transverse plane motion (90° and 180° turns) had significantly reduced peak transverse plane moments when walking with the compliant transverse plane stiffness as compared to the stiff setting. Additionally, use of the VSTA resulted in no measurable loss of mobility at self-selected walking speeds between the three settings. These preliminary results indicate that a transverse rotation adapter with variable stiffness capability could be useful for a lower limb amputee to help reduce stresses at the socket-limb interface that result in soft tissue breakdown and discomfort.
from #Audiology via ola Kala on Inoreader http://ift.tt/2cT6U4t
via IFTTT
A novel method for synchronizing motion capture with other data sources for millisecond-level precision
Publication date: Available online 4 October 2016
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Source:Gait & Posture
Author(s): V. Komisar, A.C. Novak, B. Haycock
Synchronization of multiple data collection systems is necessary for accurate temporal alignment of data, and is particularly important when considering rapid movements which occur in less than one second. This paper describes a novel method for synchronizing multiple data collection instruments including load cells and a motion capture system, using a common analog signal. An application of the synchronization method is demonstrated using biomechanical data collected during a rapid reach-to-grasp reaction, where data from motion capture and load cells are collected. Results are provided to validate and demonstrate the accuracy of the synchronization of motion capture with other data collection systems. During the reach-to-grasp trials, delays between the data collection systems ranged from 4ms to 235ms. The large range and variability in delay times between trials highlights the need for synchronization on a continual basis, rather than application of an average or constant value to correct for time delays between systems.
from #Audiology via ola Kala on Inoreader http://ift.tt/2dKhRM0
via IFTTT
Time-Varying Distortions of Binaural Information by Bilateral Hearing Aids: Effects of Nonlinear Frequency Compression.
Time-Varying Distortions of Binaural Information by Bilateral Hearing Aids: Effects of Nonlinear Frequency Compression.
Trends Hear. 2016 Oct 3;20:
Authors: Brown AD, Rodriguez FA, Portnuff CD, Goupell MJ, Tollin DJ
Abstract
In patients with bilateral hearing loss, the use of two hearing aids (HAs) offers the potential to restore the benefits of binaural hearing, including sound source localization and segregation. However, existing evidence suggests that bilateral HA users' access to binaural information, namely interaural time and level differences (ITDs and ILDs), can be compromised by device processing. Our objective was to characterize the nature and magnitude of binaural distortions caused by modern digital behind-the-ear HAs using a variety of stimuli and HA program settings. Of particular interest was a common frequency-lowering algorithm known as nonlinear frequency compression, which has not previously been assessed for its effects on binaural information. A binaural beamforming algorithm was also assessed. Wide dynamic range compression was enabled in all programs. HAs were placed on a binaural manikin, and stimuli were presented from an arc of loudspeakers inside an anechoic chamber. Stimuli were broadband noise bursts, 10-Hz sinusoidally amplitude-modulated noise bursts, or consonant-vowel-consonant speech tokens. Binaural information was analyzed in terms of ITDs, ILDs, and interaural coherence, both for whole stimuli and in a time-varying sense (i.e., within a running temporal window) across four different frequency bands (1, 2, 4, and 6 kHz). Key findings were: (a) Nonlinear frequency compression caused distortions of high-frequency envelope ITDs and significantly reduced interaural coherence. (b) For modulated stimuli, all programs caused time-varying distortion of ILDs. (c) HAs altered the relationship between ITDs and ILDs, introducing large ITD-ILD conflicts in some cases. Potential perceptual consequences of measured distortions are discussed.
PMID: 27698258 [PubMed - in process]
from #Audiology via ola Kala on Inoreader http://ift.tt/2e1jh3A
via IFTTT
Time-Varying Distortions of Binaural Information by Bilateral Hearing Aids: Effects of Nonlinear Frequency Compression.
Time-Varying Distortions of Binaural Information by Bilateral Hearing Aids: Effects of Nonlinear Frequency Compression.
Trends Hear. 2016 Oct 3;20:
Authors: Brown AD, Rodriguez FA, Portnuff CD, Goupell MJ, Tollin DJ
Abstract
In patients with bilateral hearing loss, the use of two hearing aids (HAs) offers the potential to restore the benefits of binaural hearing, including sound source localization and segregation. However, existing evidence suggests that bilateral HA users' access to binaural information, namely interaural time and level differences (ITDs and ILDs), can be compromised by device processing. Our objective was to characterize the nature and magnitude of binaural distortions caused by modern digital behind-the-ear HAs using a variety of stimuli and HA program settings. Of particular interest was a common frequency-lowering algorithm known as nonlinear frequency compression, which has not previously been assessed for its effects on binaural information. A binaural beamforming algorithm was also assessed. Wide dynamic range compression was enabled in all programs. HAs were placed on a binaural manikin, and stimuli were presented from an arc of loudspeakers inside an anechoic chamber. Stimuli were broadband noise bursts, 10-Hz sinusoidally amplitude-modulated noise bursts, or consonant-vowel-consonant speech tokens. Binaural information was analyzed in terms of ITDs, ILDs, and interaural coherence, both for whole stimuli and in a time-varying sense (i.e., within a running temporal window) across four different frequency bands (1, 2, 4, and 6 kHz). Key findings were: (a) Nonlinear frequency compression caused distortions of high-frequency envelope ITDs and significantly reduced interaural coherence. (b) For modulated stimuli, all programs caused time-varying distortion of ILDs. (c) HAs altered the relationship between ITDs and ILDs, introducing large ITD-ILD conflicts in some cases. Potential perceptual consequences of measured distortions are discussed.
PMID: 27698258 [PubMed - in process]
from #Audiology via ola Kala on Inoreader http://ift.tt/2e1jh3A
via IFTTT
Functional Expression of an Osmosensitive Cation Channel, Transient Receptor Potential Vanilloid 4, in Rat Vestibular Ganglia
Transient receptor potential vanilloid (TRPV) 4 is a nonselective cation channel expressed in sensory neurons such as those in the dorsal root and trigeminal ganglia, kidney, and inner ear. TRPV4 is activated by mechanical stress, heat, low osmotic pressure, low pH, and phorbol derivatives such as 4α-phorbol 12,13-didecanoate (4α-PDD). We investigated the expression of TRPV4 in rat vestibular ganglion (VG) neurons. The TRPV4 gene was successfully amplified from VG neuron mRNA using reverse-transcription polymerase chain reaction. Furthermore, immunoblotting showed positive expression of TRPV4 protein in VG neurons. Immunohistochemistry indicated that TRPV4 was localized predominantly on the plasma membrane of VG neurons. Calcium (Ca2+) imaging of VG neurons showed that 4α-PDD and/or hypotonic stimuli caused an increase in intracellular Ca2+ concentration ([Ca2+]i) that was almost completely inhibited by ruthenium red, a selective antagonist of TRPV channels. Interestingly, a [Ca2+]i increase was evoked by both hypotonic stimuli and 4α-PDD in approximately 38% of VG neurons. These data indicate that TRPV4 is functionally expressed in VG neurons as an ion channel and that TRPV4 likely participates in VG neurons for vestibular neurotransmission as an osmoreceptor and/or mechanoreceptor.
Audiol Neurotol 2016;21:268-274
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2d2IrNG
via IFTTT
Audiol Neurotol 2016;21:268-274
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2d2IrNG
via IFTTT
A tool for assessing case history and feedback skills in audiology students working with simulated patients.
A tool for assessing case history and feedback skills in audiology students working with simulated patients.
Int J Audiol. 2016 Dec;55(12):765-774
Authors: Hughes J, Wilson WJ, MacBean N, Hill AE
Abstract
OBJECTIVE: To develop a tool for assessing audiology students taking a case history and giving feedback with simulated patients (SP).
DESIGN: Single observation, single group design.
STUDY SAMPLE: Twenty-four first-year audiology students, five simulated patients, two clinical educators, and three evaluators.
RESULTS: The Audiology Simulated Patient Interview Rating Scale (ASPIRS) was developed consisting of six items assessing specific clinical skills, non-verbal communication, verbal communication, interpersonal skills, interviewing skills, and professional practice skills. These items are applied once for taking a case history and again for giving feedback. The ASPIRS showed very high internal consistency (α = 0.91-0.97; mean inter-item r = 0.64-0.85) and fair-to-moderate agreement between evaluators (29.2-54.2% exact and 79.2-100% near agreement; κweighted up to 0.60). It also showed fair-to-moderate absolute agreement amongst evaluators for single evaluator scores (intraclass correlation coefficient [ICC] r = 0.35-0.59) and substantial consistency of agreement amongst evaluators for three-evaluator averaged scores (ICC r = 0.62-0.81). Factor analysis showed the ASPIRS' 12 items fell into two components, one containing all feedback items and one containing all case history items.
CONCLUSION: The ASPIRS shows promise as the first published tool for assessing audiology students taking a case history and giving feedback with an SP.
PMID: 27696974 [PubMed - in process]
from #Audiology via ola Kala on Inoreader http://ift.tt/2draBVo
via IFTTT
A tool for assessing case history and feedback skills in audiology students working with simulated patients.
A tool for assessing case history and feedback skills in audiology students working with simulated patients.
Int J Audiol. 2016 Dec;55(12):765-774
Authors: Hughes J, Wilson WJ, MacBean N, Hill AE
Abstract
OBJECTIVE: To develop a tool for assessing audiology students taking a case history and giving feedback with simulated patients (SP).
DESIGN: Single observation, single group design.
STUDY SAMPLE: Twenty-four first-year audiology students, five simulated patients, two clinical educators, and three evaluators.
RESULTS: The Audiology Simulated Patient Interview Rating Scale (ASPIRS) was developed consisting of six items assessing specific clinical skills, non-verbal communication, verbal communication, interpersonal skills, interviewing skills, and professional practice skills. These items are applied once for taking a case history and again for giving feedback. The ASPIRS showed very high internal consistency (α = 0.91-0.97; mean inter-item r = 0.64-0.85) and fair-to-moderate agreement between evaluators (29.2-54.2% exact and 79.2-100% near agreement; κweighted up to 0.60). It also showed fair-to-moderate absolute agreement amongst evaluators for single evaluator scores (intraclass correlation coefficient [ICC] r = 0.35-0.59) and substantial consistency of agreement amongst evaluators for three-evaluator averaged scores (ICC r = 0.62-0.81). Factor analysis showed the ASPIRS' 12 items fell into two components, one containing all feedback items and one containing all case history items.
CONCLUSION: The ASPIRS shows promise as the first published tool for assessing audiology students taking a case history and giving feedback with an SP.
PMID: 27696974 [PubMed - in process]
from #Audiology via ola Kala on Inoreader http://ift.tt/2draBVo
via IFTTT
Εγγραφή σε:
Αναρτήσεις (Atom)