InnerScope Launches PSAP Web Store

​InnerScope Hearing Technologies (http://www.innd.com/) now offers purchase options and hearing resources to personal sound amplifier products (PSAPs) consumers on its direct-to-consumer e-commerce site, Hearingbenefit.com. They can sign up to receive an e-book produced by InnerScope called The Senior Medical Controversy on Hearingbenefit.com to learn about the consequences of untreated hearing loss, including cognitive issues such as Alzheimer's and dementia. InnerScope has also created a separate landing page (http://www.howtohearbetter.com/) to assist consumers through the evaluation and decision phase of choosing a device. Matthew Moore, CEO of InnerScope, said once people click onto their e-commerce store, it is easy for them to navigate and make a decision to purchase. "We have taken the stress off the buying process, by offering easy payments with zero down and zero interest. We know that for years the tens of millions of hearing impaired people have been an underserved market… We offer these people through our Hearingbenefit.com website easy and simple access to hearing products that can help improve their hearing immediately without hurting their pocketbook, and even a money back guarantee," Moore said.

Published: 1/26/2018 7:36:00 AM

from #Audiology via xlomafota13 on Inoreader http://ift.tt/2DDmBuQ
via IFTTT

InnerScope Launches PSAP Web Store

​InnerScope Hearing Technologies (http://www.innd.com/) now offers purchase options and hearing resources to personal sound amplifier products (PSAPs) consumers on its direct-to-consumer e-commerce site, Hearingbenefit.com. They can sign up to receive an e-book produced by InnerScope called The Senior Medical Controversy on Hearingbenefit.com to learn about the consequences of untreated hearing loss, including cognitive issues such as Alzheimer's and dementia. InnerScope has also created a separate landing page (http://www.howtohearbetter.com/) to assist consumers through the evaluation and decision phase of choosing a device. Matthew Moore, CEO of InnerScope, said once people click onto their e-commerce store, it is easy for them to navigate and make a decision to purchase. "We have taken the stress off the buying process, by offering easy payments with zero down and zero interest. We know that for years the tens of millions of hearing impaired people have been an underserved market… We offer these people through our Hearingbenefit.com website easy and simple access to hearing products that can help improve their hearing immediately without hurting their pocketbook, and even a money back guarantee," Moore said.

Published: 1/26/2018 7:36:00 AM

from #Audiology via ola Kala on Inoreader http://ift.tt/2DDmBuQ
via IFTTT

InnerScope Launches PSAP Web Store

​InnerScope Hearing Technologies (http://www.innd.com/) now offers purchase options and hearing resources to personal sound amplifier products (PSAPs) consumers on its direct-to-consumer e-commerce site, Hearingbenefit.com. They can sign up to receive an e-book produced by InnerScope called The Senior Medical Controversy on Hearingbenefit.com to learn about the consequences of untreated hearing loss, including cognitive issues such as Alzheimer's and dementia. InnerScope has also created a separate landing page (http://www.howtohearbetter.com/) to assist consumers through the evaluation and decision phase of choosing a device. Matthew Moore, CEO of InnerScope, said once people click onto their e-commerce store, it is easy for them to navigate and make a decision to purchase. "We have taken the stress off the buying process, by offering easy payments with zero down and zero interest. We know that for years the tens of millions of hearing impaired people have been an underserved market… We offer these people through our Hearingbenefit.com website easy and simple access to hearing products that can help improve their hearing immediately without hurting their pocketbook, and even a money back guarantee," Moore said.

Published: 1/26/2018 7:36:00 AM

from #Audiology via ola Kala on Inoreader http://ift.tt/2DDmBuQ
via IFTTT

Binaural model-based dynamic-range compression

.


from #Audiology via xlomafota13 on Inoreader http://ift.tt/2DGE1Lg
via IFTTT

Binaural model-based dynamic-range compression

.


from #Audiology via ola Kala on Inoreader http://ift.tt/2DGE1Lg
via IFTTT

Novel frameshift mutation in the KCNQ1 gene responsible for Jervell and Lange-Nielsen syndrome.

Related Articles

Novel frameshift mutation in the KCNQ1 gene responsible for Jervell and Lange-Nielsen syndrome.

Iran J Basic Med Sci. 2018 Jan;21(1):108-111

Authors: Amirian A, Dalili SM, Zafari Z, Saber S, Karimipoor M, Akbari V, Fazelifar AF, Zeinali S

Abstract
Objectives: Jervell and Lange-Nielsen syndrome is an autosomal recessive disorder caused by mutations in KCNQ1 or KCNE1 genes. The disease is characterized by sensorineural hearing loss and long QT syndrome.
Materials and Methods: Here we present a 3.5-year-old female patient, an offspring of consanguineous marriage, who had a history of recurrent syncope and congenital sensorineural deafness. The patient and the family members were screened for mutations in KCNQ1 gene by linkage analysis and DNA sequencing.
Results: DNA sequencing showed a c.1532_1534delG (p. A512Pfs*81) mutation in the KCNQ1 gene in homozygous form. The results of short tandem repeat (STR) markers showed that the disease in the family is linked to the KCNQ1 gene. The mutation was confirmed in the parents in heterozygous form.
Conclusion: This is the first report of this variant in KCNQ1 gene in an Iranian family. The data of this study could be used for early diagnosis of the condition in the family and genetic counseling.

PMID: 29372044 [PubMed]

from #Audiology via xlomafota13 on Inoreader http://ift.tt/2DBH82Z
via IFTTT

Gene therapy for inherited retinal and optic nerve degenerations.

Related Articles

Gene therapy for inherited retinal and optic nerve degenerations.

Expert Opin Biol Ther. 2018 Jan;18(1):37-49

Authors: Moore NA, Morral N, Ciulla TA, Bracha P

Abstract
INTRODUCTION: The eye is a target for investigational gene therapy due to the monogenic nature of many inherited retinal and optic nerve degenerations (IRD), its accessibility, tight blood-ocular barrier, the ability to non-invasively monitor for functional and anatomic outcomes, as well as its relative immune privileged state.Vectors currently used in IRD clinical trials include adeno-associated virus (AAV), small single-stranded DNA viruses, and lentivirus, RNA viruses of the retrovirus family. Both can transduce non-dividing cells, but AAV are non-integrating, while lentivirus integrate into the host cell genome, and have a larger transgene capacity. Areas covered: This review covers Leber's congenital amaurosis, choroideremia, retinitis pigmentosa, Usher syndrome, Stargardt disease, Leber's hereditary optic neuropathy, Achromatopsia, and X-linked retinoschisis. Expert opinion: Despite great potential, gene therapy for IRD raises many questions, including the potential for less invasive intravitreal versus subretinal delivery, efficacy, safety, and longevity of response, as well as acceptance of novel study endpoints by regulatory bodies, patients, clinicians, and payers. Also, ultimate adoption of gene therapy for IRD will require widespread genetic screening to identify and diagnose patients based on genotype instead of phenotype.

PMID: 29057663 [PubMed - indexed for MEDLINE]

from #Audiology via xlomafota13 on Inoreader http://ift.tt/2z3k5PW
via IFTTT

Binaural model-based dynamic-range compression

.


from #Audiology via ola Kala on Inoreader http://ift.tt/2DGE1Lg
via IFTTT

A Guerilla Guide to Common Problems in 'Neurostatistics': Essential Statistical Topics in Neuroscience.

Related Articles

A Guerilla Guide to Common Problems in 'Neurostatistics': Essential Statistical Topics in Neuroscience.

J Undergrad Neurosci Educ. 2017;16(1):R1-R12

Authors: Smith PF

Abstract
Effective inferential statistical analysis is essential for high quality studies in neuroscience. However, recently, neuroscience has been criticised for the poor use of experimental design and statistical analysis. Many of the statistical issues confronting neuroscience are similar to other areas of biology; however, there are some that occur more regularly in neuroscience studies. This review attempts to provide a succinct overview of some of the major issues that arise commonly in the analyses of neuroscience data. These include: the non-normal distribution of the data; inequality of variance between groups; extensive correlation in data for repeated measurements across time or space; excessive multiple testing; inadequate statistical power due to small sample sizes; pseudo-replication; and an over-emphasis on binary conclusions about statistical significance as opposed to effect sizes. Statistical analysis should be viewed as just another neuroscience tool, which is critical to the final outcome of the study. Therefore, it needs to be done well and it is a good idea to be proactive and seek help early, preferably before the study even begins.

PMID: 29371855 [PubMed]

from #Audiology via ola Kala on Inoreader http://ift.tt/2BwYH2l
via IFTTT

A Guerilla Guide to Common Problems in 'Neurostatistics': Essential Statistical Topics in Neuroscience.

Related Articles

A Guerilla Guide to Common Problems in 'Neurostatistics': Essential Statistical Topics in Neuroscience.

J Undergrad Neurosci Educ. 2017;16(1):R1-R12

Authors: Smith PF

Abstract
Effective inferential statistical analysis is essential for high quality studies in neuroscience. However, recently, neuroscience has been criticised for the poor use of experimental design and statistical analysis. Many of the statistical issues confronting neuroscience are similar to other areas of biology; however, there are some that occur more regularly in neuroscience studies. This review attempts to provide a succinct overview of some of the major issues that arise commonly in the analyses of neuroscience data. These include: the non-normal distribution of the data; inequality of variance between groups; extensive correlation in data for repeated measurements across time or space; excessive multiple testing; inadequate statistical power due to small sample sizes; pseudo-replication; and an over-emphasis on binary conclusions about statistical significance as opposed to effect sizes. Statistical analysis should be viewed as just another neuroscience tool, which is critical to the final outcome of the study. Therefore, it needs to be done well and it is a good idea to be proactive and seek help early, preferably before the study even begins.

PMID: 29371855 [PubMed]

from #Audiology via ola Kala on Inoreader http://ift.tt/2BwYH2l
via IFTTT