Τρίτη 20 Ιουνίου 2017

Dr. Ries’ study in the news!

“SDSU neuroscientist Stephanie Ries explores the complex brain connections employed during word retrieval.

When you look at a picture of a mug, the neurons that store your memory of what a mug is begin firing. But it’s not a pinpoint process; a host of neurons that code for related ideas and items—bowl, coffee, spoon, plate, breakfast—are activated as well.  The word mug must then be selected among its neighbors. Dr Ries’ study shows these two processes, word activation and selection, co-occur in time and space.”

 

 



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JDP students at the International Symposium on Biligualism

Our JDP students in Language and Communicative Disorders, Irina Potapova, Philip Combiths, and Jonathan Robinson Anthony, had a great time at the International Symposium on Biligualism in Limerick, Ireland, last week. Great job everyone!

[See image gallery at slhs.sdsu.edu]

 

 



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Dr. Ries’ study in the news!

“SDSU neuroscientist Stephanie Ries explores the complex brain connections employed during word retrieval.

When you look at a picture of a mug, the neurons that store your memory of what a mug is begin firing. But it’s not a pinpoint process; a host of neurons that code for related ideas and items—bowl, coffee, spoon, plate, breakfast—are activated as well.  The word mug must then be selected among its neighbors. Dr Ries’ study shows these two processes, word activation and selection, co-occur in time and space.”

 

 



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JDP students at the International Symposium on Biligualism

Our JDP students in Language and Communicative Disorders, Irina Potapova, Philip Combiths, and Jonathan Robinson Anthony, had a great time at the International Symposium on Biligualism in Limerick, Ireland, last week. Great job everyone!

[See image gallery at slhs.sdsu.edu]

 

 



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Dr. Ries’ study in the news!

“SDSU neuroscientist Stephanie Ries explores the complex brain connections employed during word retrieval.

When you look at a picture of a mug, the neurons that store your memory of what a mug is begin firing. But it’s not a pinpoint process; a host of neurons that code for related ideas and items—bowl, coffee, spoon, plate, breakfast—are activated as well.  The word mug must then be selected among its neighbors. Dr Ries’ study shows these two processes, word activation and selection, co-occur in time and space.”

 

 



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JDP students at the International Symposium on Biligualism

Our JDP students in Language and Communicative Disorders, Irina Potapova, Philip Combiths, and Jonathan Robinson Anthony, had a great time at the International Symposium on Biligualism in Limerick, Ireland, last week. Great job everyone!

[See image gallery at slhs.sdsu.edu]

 

 



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Characterization of slow-cycling cells in the mouse cochlear lateral wall

by Yang Li, Kotaro Watanabe, Masato Fujioka, Kaoru Ogawa

Cochlear spiral ligament fibrocytes (SLFs) play essential roles in the physiology of hearing including ion recycling and the generation of endocochlear potential. In adult animals, SLFs can repopulate after damages, yet little is known about the characteristics of proliferating cells that support SLFs’ self-renewal. Here we report in detail about the characteristics of cycling cells in the spiral ligament (SL). Fifteen P6 mice and six noise-exposed P28 mice were injected with 5-bromo-2′-deoxyuridine (BrdU) for 7 days and we chased BrdU retaining cells for as long as 60 days. Immunohistochemistry revealed that the BrdU positive IB4 (an endotherial marker) negative cells expressed an early SLF marker Pou3f4 but negative for cleaved-Caspase 3. Marker studies revealed that type 3 SLFs displayed significantly higher percentage of BrdU+ cells compared to other subtypes. Notably, the cells retained BrdU until P72, demonstrating they were dividing slowly. In the noise-damaged mice, in contrast to the loss of the other types, the number of type 3 SLFs did not altered and the BrdU incorporating- phosphorylated Histone H3 positive type 3 cells were increased from day 1 to 14 after noise exposure. Furthermore, the cells repopulating type 1 area, where the cells diminished profoundly after damage, were positive for the type 3 SLF markers. Collectively, in the latral wall of the cochlea, type 3 SLFs have the stem cell capacity and may contribute to the endogenous regeneration of lateral wall spiral ligament. Manipulating type 3 cells may be employed for potential regenerative therapies.

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The Effect of Stimulus Valence on Lexical Retrieval in Younger and Older Adults

Purpose
Although there is evidence that emotional valence of stimuli impacts lexical processes, there is limited work investigating its specific impact on lexical retrieval. The current study aimed to determine the degree to which emotional valence of pictured stimuli impacts naming latencies in healthy younger and older adults.
Method
Eighteen healthy younger adults and 18 healthy older adults named positive, negative, and neutral images, and reaction time was measured.
Results
Reaction times for positive and negative images were significantly longer than reaction times for neutral images. Reaction times for positive and negative images were not significantly different. Whereas older adults demonstrated significantly longer naming latencies overall than younger adults, the discrepancy in latency with age was far greater when naming emotional pictures.
Conclusions
Emotional arousal of pictures appears to impact naming latency in younger and older adults. We hypothesize that the increase in naming latency for emotional stimuli is the result of a necessary disengagement of attentional resources from the emotional images prior to completion of the naming task. We propose that this process may affect older adults disproportionately due to a decline in attentional resources as part of normal aging, combined with a greater attentional preference for emotional stimuli.

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The Effect of Stimulus Valence on Lexical Retrieval in Younger and Older Adults

Purpose
Although there is evidence that emotional valence of stimuli impacts lexical processes, there is limited work investigating its specific impact on lexical retrieval. The current study aimed to determine the degree to which emotional valence of pictured stimuli impacts naming latencies in healthy younger and older adults.
Method
Eighteen healthy younger adults and 18 healthy older adults named positive, negative, and neutral images, and reaction time was measured.
Results
Reaction times for positive and negative images were significantly longer than reaction times for neutral images. Reaction times for positive and negative images were not significantly different. Whereas older adults demonstrated significantly longer naming latencies overall than younger adults, the discrepancy in latency with age was far greater when naming emotional pictures.
Conclusions
Emotional arousal of pictures appears to impact naming latency in younger and older adults. We hypothesize that the increase in naming latency for emotional stimuli is the result of a necessary disengagement of attentional resources from the emotional images prior to completion of the naming task. We propose that this process may affect older adults disproportionately due to a decline in attentional resources as part of normal aging, combined with a greater attentional preference for emotional stimuli.

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The Effect of Stimulus Valence on Lexical Retrieval in Younger and Older Adults

Purpose
Although there is evidence that emotional valence of stimuli impacts lexical processes, there is limited work investigating its specific impact on lexical retrieval. The current study aimed to determine the degree to which emotional valence of pictured stimuli impacts naming latencies in healthy younger and older adults.
Method
Eighteen healthy younger adults and 18 healthy older adults named positive, negative, and neutral images, and reaction time was measured.
Results
Reaction times for positive and negative images were significantly longer than reaction times for neutral images. Reaction times for positive and negative images were not significantly different. Whereas older adults demonstrated significantly longer naming latencies overall than younger adults, the discrepancy in latency with age was far greater when naming emotional pictures.
Conclusions
Emotional arousal of pictures appears to impact naming latency in younger and older adults. We hypothesize that the increase in naming latency for emotional stimuli is the result of a necessary disengagement of attentional resources from the emotional images prior to completion of the naming task. We propose that this process may affect older adults disproportionately due to a decline in attentional resources as part of normal aging, combined with a greater attentional preference for emotional stimuli.

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Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice.

Related Articles

Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice.

Front Neurosci. 2017;11:304

Authors: Lauer AM

Abstract
Studies have suggested a role of weakened medial olivocochlear (OC) efferent feedback in accelerated hearing loss and increased susceptibility to noise. The present study investigated the progression of hearing loss with age and exposure to a noisy environment in medial OC-deficient mice. Alpha9 nicotinic acetylcholine receptor knockout (α9KO) and wild types were screened for hearing loss using auditory brainstem responses. α9KO mice housed in a quiet environment did not show increased hearing loss compared to wild types in young adulthood and middle age. Challenging the medial OC system by housing in a noisy environment did not increase hearing loss in α9KO mice compared to wild types. ABR wave 1 amplitudes also did not show differences between α9KO mice and wild types. These data suggest that deficient medial OC feedback does not result in early onset of hearing loss.

PMID: 28626386 [PubMed - in process]



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Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice.

Related Articles

Minimal Effects of Age and Exposure to a Noisy Environment on Hearing in Alpha9 Nicotinic Receptor Knockout Mice.

Front Neurosci. 2017;11:304

Authors: Lauer AM

Abstract
Studies have suggested a role of weakened medial olivocochlear (OC) efferent feedback in accelerated hearing loss and increased susceptibility to noise. The present study investigated the progression of hearing loss with age and exposure to a noisy environment in medial OC-deficient mice. Alpha9 nicotinic acetylcholine receptor knockout (α9KO) and wild types were screened for hearing loss using auditory brainstem responses. α9KO mice housed in a quiet environment did not show increased hearing loss compared to wild types in young adulthood and middle age. Challenging the medial OC system by housing in a noisy environment did not increase hearing loss in α9KO mice compared to wild types. ABR wave 1 amplitudes also did not show differences between α9KO mice and wild types. These data suggest that deficient medial OC feedback does not result in early onset of hearing loss.

PMID: 28626386 [PubMed - in process]



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Factors related to tinnitus and hyperacusis handicap in older people.

Related Articles

Factors related to tinnitus and hyperacusis handicap in older people.

Int J Audiol. 2017 Jun 18;:1-8

Authors: Aazh H, Lammaing K, Moore BCJ

Abstract
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people.
DESIGN: Retrospective cross-sectional.
STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years.
RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2.9, p < 0.001) and the effect of tinnitus on the patient's life as measured via the VAS (b = 3.9, p < 0.001). Hyperacusis handicap as measured via the Hyperacusis Questionnaire (HQ) was significantly predicted by the score on the depression subscale of the Hospital Anxiety and Depression Scale (HADS) (b = 0.8, p < 0.001) and to a small extent by the THI score (b = 0.07, p = 0.048). Insomnia scores as measured via the Insomnia Severity Index (ISI) were significantly predicted by scores on the depression subscale of the HADS (b = 0.46, p = 0.007).
CONCLUSIONS: Since tinnitus annoyance significantly predicts tinnitus handicap, it is important to explore factors associated with annoyance that may be useful in designing appropriate rehabilitative interventions aimed at reducing tinnitus handicap in older people. Future studies should explore whether hyperacusis and insomnia in older people with tinnitus need to be managed in conjunction with treatment for depression.

PMID: 28625091 [PubMed - as supplied by publisher]



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Factors related to tinnitus and hyperacusis handicap in older people.

Related Articles

Factors related to tinnitus and hyperacusis handicap in older people.

Int J Audiol. 2017 Jun 18;:1-8

Authors: Aazh H, Lammaing K, Moore BCJ

Abstract
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people.
DESIGN: Retrospective cross-sectional.
STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years.
RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2.9, p < 0.001) and the effect of tinnitus on the patient's life as measured via the VAS (b = 3.9, p < 0.001). Hyperacusis handicap as measured via the Hyperacusis Questionnaire (HQ) was significantly predicted by the score on the depression subscale of the Hospital Anxiety and Depression Scale (HADS) (b = 0.8, p < 0.001) and to a small extent by the THI score (b = 0.07, p = 0.048). Insomnia scores as measured via the Insomnia Severity Index (ISI) were significantly predicted by scores on the depression subscale of the HADS (b = 0.46, p = 0.007).
CONCLUSIONS: Since tinnitus annoyance significantly predicts tinnitus handicap, it is important to explore factors associated with annoyance that may be useful in designing appropriate rehabilitative interventions aimed at reducing tinnitus handicap in older people. Future studies should explore whether hyperacusis and insomnia in older people with tinnitus need to be managed in conjunction with treatment for depression.

PMID: 28625091 [PubMed - as supplied by publisher]



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A Comparison of Parenting Dimensions Between Deaf and Hearing Children.

Related Articles

A Comparison of Parenting Dimensions Between Deaf and Hearing Children.

Clin Nurs Res. 2016 Jun;25(3):342-54

Authors: Ekim A, Ocakci AF

Abstract
Effective parenting is vital for intellectual, physical, social, and emotional development of a child. This study examined the differences between the parenting dimensions of deaf children and healthy ones. The sample of the study consisted of 292 children and their parents (146 of them deaf children and 146 of them healthy ones). Dimensions of parenting (warmth, rejection, structure, chaos, autonomy, and coercion) were measured using the Parent as Social Context Questionnaire. The mean scores of the positive parenting dimensions of warmth and autonomy of deaf children were significantly lower; however, the mean scores of the negative dimensions of chaos and coercion of deaf children were significantly higher than those of healthy ones. Deaf children can become successful adults with the help of their parents. Our results regarding parenting dimensions will be a guide for future nursing interventions planned to develop the relationships between deaf children and their parents.

PMID: 26620870 [PubMed - indexed for MEDLINE]



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Factors related to tinnitus and hyperacusis handicap in older people.

Related Articles

Factors related to tinnitus and hyperacusis handicap in older people.

Int J Audiol. 2017 Jun 18;:1-8

Authors: Aazh H, Lammaing K, Moore BCJ

Abstract
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people.
DESIGN: Retrospective cross-sectional.
STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years.
RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2.9, p < 0.001) and the effect of tinnitus on the patient's life as measured via the VAS (b = 3.9, p < 0.001). Hyperacusis handicap as measured via the Hyperacusis Questionnaire (HQ) was significantly predicted by the score on the depression subscale of the Hospital Anxiety and Depression Scale (HADS) (b = 0.8, p < 0.001) and to a small extent by the THI score (b = 0.07, p = 0.048). Insomnia scores as measured via the Insomnia Severity Index (ISI) were significantly predicted by scores on the depression subscale of the HADS (b = 0.46, p = 0.007).
CONCLUSIONS: Since tinnitus annoyance significantly predicts tinnitus handicap, it is important to explore factors associated with annoyance that may be useful in designing appropriate rehabilitative interventions aimed at reducing tinnitus handicap in older people. Future studies should explore whether hyperacusis and insomnia in older people with tinnitus need to be managed in conjunction with treatment for depression.

PMID: 28625091 [PubMed - as supplied by publisher]



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Factors related to tinnitus and hyperacusis handicap in older people.

Related Articles

Factors related to tinnitus and hyperacusis handicap in older people.

Int J Audiol. 2017 Jun 18;:1-8

Authors: Aazh H, Lammaing K, Moore BCJ

Abstract
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people.
DESIGN: Retrospective cross-sectional.
STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years.
RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2.9, p < 0.001) and the effect of tinnitus on the patient's life as measured via the VAS (b = 3.9, p < 0.001). Hyperacusis handicap as measured via the Hyperacusis Questionnaire (HQ) was significantly predicted by the score on the depression subscale of the Hospital Anxiety and Depression Scale (HADS) (b = 0.8, p < 0.001) and to a small extent by the THI score (b = 0.07, p = 0.048). Insomnia scores as measured via the Insomnia Severity Index (ISI) were significantly predicted by scores on the depression subscale of the HADS (b = 0.46, p = 0.007).
CONCLUSIONS: Since tinnitus annoyance significantly predicts tinnitus handicap, it is important to explore factors associated with annoyance that may be useful in designing appropriate rehabilitative interventions aimed at reducing tinnitus handicap in older people. Future studies should explore whether hyperacusis and insomnia in older people with tinnitus need to be managed in conjunction with treatment for depression.

PMID: 28625091 [PubMed - as supplied by publisher]



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