Eyes and Ears—Letter to the Editor

Good Morning Chris,

I hope this e-mail finds you well, warm, and in good spirits. My name is Joshua Huppert and I'm currently a pediatric audiologist and member of the Pediatric Balance Team at Children's Hospital Colorado (CHCO). I will only remain at CHCO for another two or so weeks, as I've accepted a position at University of Miami Ear Institute, where I will not only be a pediatric audiologist, but also hold a faculty appointment as well, allowing me to grow, develop, and hone my skills as a clinician AND a future educator.

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CT-based Morphometric Analysis of Professional Opera Singers' Vocal Folds

Publication date: Available online 21 March 2018
Source:Journal of Voice
Author(s): Pedro Clarós, Aleksandra Z. Sobolewska, Antonio Doménech-Clarós, Astrid Clarós-Pujol, Carmen Pujol, Andrés Clarós
Purpose and Study DesignOur work aimed to study the relationship between the length of vocal folds and classical voice type among professional opera singers. Also, the present paper attempts to assess if individual features such as height and body mass index are associated with the vocal folds length (VFL) and the vocal range. Our research compared VFL and voice type by evaluation of neck computed tomography imaging of professional opera singers obtained between 2009 and 2015. Vocal range was measured after scanning procedure by a speech-language pathologist. The results were used to compare VFL with vocal range, voice type, and individual features of every singer.Material and MethodsThe group included 93 opera singers (female: 31 sopranos, 15 mezzos, and 5 contraltos; male: 17 tenors, 16 baritones, 6 basses, and 3 countertenors). Different values such as VFL, vocal range, and individuals' features (height, weight, body mass index) were analyzed statistically.ResultsSome significant differences and correlation were found. The VFL was diversified between classical voice types. VFL for soprano, mezzo-soprano, and bass was significantly different from every other type of voice. The vocal range has been shown to have a negative correlation with VFL value, which reflects the narrowest vocal range among bass voices. The analysis confirmed a linear correlation between VFL and individual features of the body such as height and body mass index.ConclusionPresented data support the hypothesis that there are significant differences of VFL, vocal range, and body morphology between professional singers of different voice classification.



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Magnitude and phase of three-dimensional (3D) velocity vector: Application to measurement of cochlear promontory motion during bone conduction sound transmission

Publication date: Available online 21 March 2018
Source:Hearing Research
Author(s): Ivo Dobrev, Jae Hoon Sim
Recent measurements of vibrational motion to assess sound transmission through ear structures and skull contents have included three-dimensional (3D) behavior. The 3D motion of a point has been described with the three orthogonal components in the 3D space. In this article, a method to represent the 3D velocity with the magnitude and phase of the resultant velocity is introduced. This method was applied to the measurement of cochlear promontory motion as an indication of bone conduction (BC) sound transmission. The promontory motions were measured on the ipsilateral and contralateral sides, and the transcranial attenuation and phase delay of the contralateral side relative to the ipsilateral side were calculated. The transcranial attenuation and phase delay calculated with the maximum magnitudes and corresponding phases of the resultant were a better fit to the interaural threshold difference and transcranial time interval between the ipsilateral and contralateral sides as reported in the literature, than the attenuation and phase delay calculated with any individual Cartesian motion component.



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Magnitude and phase of three-dimensional (3D) velocity vector: Application to measurement of cochlear promontory motion during bone conduction sound transmission

Publication date: Available online 21 March 2018
Source:Hearing Research
Author(s): Ivo Dobrev, Jae Hoon Sim
Recent measurements of vibrational motion to assess sound transmission through ear structures and skull contents have included three-dimensional (3D) behavior. The 3D motion of a point has been described with the three orthogonal components in the 3D space. In this article, a method to represent the 3D velocity with the magnitude and phase of the resultant velocity is introduced. This method was applied to the measurement of cochlear promontory motion as an indication of bone conduction (BC) sound transmission. The promontory motions were measured on the ipsilateral and contralateral sides, and the transcranial attenuation and phase delay of the contralateral side relative to the ipsilateral side were calculated. The transcranial attenuation and phase delay calculated with the maximum magnitudes and corresponding phases of the resultant were a better fit to the interaural threshold difference and transcranial time interval between the ipsilateral and contralateral sides as reported in the literature, than the attenuation and phase delay calculated with any individual Cartesian motion component.



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Magnitude and phase of three-dimensional (3D) velocity vector: Application to measurement of cochlear promontory motion during bone conduction sound transmission

Publication date: Available online 21 March 2018
Source:Hearing Research
Author(s): Ivo Dobrev, Jae Hoon Sim
Recent measurements of vibrational motion to assess sound transmission through ear structures and skull contents have included three-dimensional (3D) behavior. The 3D motion of a point has been described with the three orthogonal components in the 3D space. In this article, a method to represent the 3D velocity with the magnitude and phase of the resultant velocity is introduced. This method was applied to the measurement of cochlear promontory motion as an indication of bone conduction (BC) sound transmission. The promontory motions were measured on the ipsilateral and contralateral sides, and the transcranial attenuation and phase delay of the contralateral side relative to the ipsilateral side were calculated. The transcranial attenuation and phase delay calculated with the maximum magnitudes and corresponding phases of the resultant were a better fit to the interaural threshold difference and transcranial time interval between the ipsilateral and contralateral sides as reported in the literature, than the attenuation and phase delay calculated with any individual Cartesian motion component.



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Magnitude and phase of three-dimensional (3D) velocity vector: Application to measurement of cochlear promontory motion during bone conduction sound transmission

Publication date: Available online 21 March 2018
Source:Hearing Research
Author(s): Ivo Dobrev, Jae Hoon Sim
Recent measurements of vibrational motion to assess sound transmission through ear structures and skull contents have included three-dimensional (3D) behavior. The 3D motion of a point has been described with the three orthogonal components in the 3D space. In this article, a method to represent the 3D velocity with the magnitude and phase of the resultant velocity is introduced. This method was applied to the measurement of cochlear promontory motion as an indication of bone conduction (BC) sound transmission. The promontory motions were measured on the ipsilateral and contralateral sides, and the transcranial attenuation and phase delay of the contralateral side relative to the ipsilateral side were calculated. The transcranial attenuation and phase delay calculated with the maximum magnitudes and corresponding phases of the resultant were a better fit to the interaural threshold difference and transcranial time interval between the ipsilateral and contralateral sides as reported in the literature, than the attenuation and phase delay calculated with any individual Cartesian motion component.



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Magnitude and phase of three-dimensional (3D) velocity vector: Application to measurement of cochlear promontory motion during bone conduction sound transmission

Publication date: Available online 21 March 2018
Source:Hearing Research
Author(s): Ivo Dobrev, Jae Hoon Sim
Recent measurements of vibrational motion to assess sound transmission through ear structures and skull contents have included three-dimensional (3D) behavior. The 3D motion of a point has been described with the three orthogonal components in the 3D space. In this article, a method to represent the 3D velocity with the magnitude and phase of the resultant velocity is introduced. This method was applied to the measurement of cochlear promontory motion as an indication of bone conduction (BC) sound transmission. The promontory motions were measured on the ipsilateral and contralateral sides, and the transcranial attenuation and phase delay of the contralateral side relative to the ipsilateral side were calculated. The transcranial attenuation and phase delay calculated with the maximum magnitudes and corresponding phases of the resultant were a better fit to the interaural threshold difference and transcranial time interval between the ipsilateral and contralateral sides as reported in the literature, than the attenuation and phase delay calculated with any individual Cartesian motion component.



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A novel mutation in the SMPX gene associated with X-linked nonsyndromic sensorineural hearing loss in a Chinese family.

A novel mutation in the SMPX gene associated with X-linked nonsyndromic sensorineural hearing loss in a Chinese family.

J Hum Genet. 2018 Mar 20;:

Authors: Deng Y, Niu Z, Fan L, Ling J, Chen H, Cai X, Mei L, He C, Zhang X, Wen J, Li M, Li W, Li T, Sang S, Liu Y, Feng Y

Abstract
X-linked inheritance is very rare and is estimated to account for only 1-5% of all nonsyndromic hearing loss cases. We found a multiplex family from China segregating with X-linked nonsyndromic hearing loss. After exclusive analysis of 10 common variations of three hearing loss-related genes, GJB2, mtDNA12srRNA and SLC26A4, a novel truncated variant of SMPX, c.87dupA (p.Gly30Argfs*12) (NCBI ClinVar Submission ID: SUB3136126), was identified by whole-exome sequencing. This variant was co-segregated with hearing loss in the entire family and was absent in 576 unrelated ethnically and geographically matched controls. We also detected a single nucleotide variation in two male controls with normal hearing, SMPX c.55A>G (p.Asn19Asp), which has been annotated as a rare variant in the Single Nucleotide Polymorphism (dbSNP) (rs759552778) and Exome Aggregation Consortium (ExAC) databases. This study has enriched the mutation spectrum of the SMPX gene.

PMID: 29559740 [PubMed - as supplied by publisher]

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