Publication date: Available online 30 June 2017
Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Παρασκευή 30 Ιουνίου 2017
Simultaneous masking between electric and acoustic stimulation in cochlear implant users with residual low-frequency hearing
Publication date: Available online 30 June 2017
Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Simultaneous masking between electric and acoustic stimulation in cochlear implant users with residual low-frequency hearing
Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Simultaneous masking between electric and acoustic stimulation in cochlear implant users with residual low-frequency hearing
Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Simultaneous masking between electric and acoustic stimulation in cochlear implant users with residual low-frequency hearing
Source:Hearing Research
Author(s): Benjamin Krüger, Andreas Büchner, Waldo Nogueira
Ipsilateral electric-acoustic stimulation (EAS) is becoming increasingly important in cochlear implant (CI) treatment. Improvements in electrode designs and surgical techniques have contributed to improved hearing preservation during implantation. Consequently, CI implantation criteria have been expanded toward people with significant residual low-frequency hearing, who may benefit from the combined use of both the electric and acoustic stimulation in the same ear. However, only few studies have investigated the mutual interaction between electric and acoustic stimulation modalities.This work characterizes the interaction between both stimulation modalities using psychophysical masking experiments and cone beam computer tomography (CBCT). Two psychophysical experiments for electric and acoustic masking were performed to measure the hearing threshold elevation of a probe stimulus in the presence of a masker stimulus. For electric masking, the probe stimulus was an acoustic tone while the masker stimulus was an electric pulse train. For acoustic masking, the probe stimulus was an electric pulse train and the masker stimulus was an acoustic tone.Five EAS users, implanted with a CI and ipsilateral residual low-frequency hearing, participated in the study. Masking was determined at different electrodes and different acoustic frequencies. CBCT scans were used to determine the individual place-pitch frequencies of the intracochlear electrode contacts by using the Stakhovskaya place-to-frequency transformation. This allows the characterization of masking as a function of the difference between electric and acoustic stimulation sites, which we term the electric-acoustic frequency difference (EAFD).The results demonstrate a significant elevation of detection thresholds for both experiments. In electric masking, acoustic-tone thresholds increased exponentially with decreasing EAFD. In contrast, for the acoustic masking experiment, threshold elevations were present regardless of the tested EAFDs. Based on the present findings, we conclude that there is an asymmetry between the electric and the acoustic masker modalities. These observations have implications for the design and fitting of EAS sound-coding strategies.
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Regulation of KCNQ/Kv7 family voltage-gated K(+) channels by lipids.
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Related Articles |
Regulation of KCNQ/Kv7 family voltage-gated K(+) channels by lipids.
Biochim Biophys Acta. 2017 04;1859(4):586-597
Authors: Taylor KC, Sanders CR
Abstract
Many years of studies have established that lipids can impact membrane protein structure and function through bulk membrane effects, by direct but transient annular interactions with the bilayer-exposed surface of protein transmembrane domains, and by specific binding to protein sites. Here, we focus on how phosphatidylinositol 4,5-bisphosphate (PIP2) and polyunsaturated fatty acids (PUFAs) impact ion channel function and how the structural details of the interactions of these lipids with ion channels are beginning to emerge. We focus on the Kv7 (KCNQ) subfamily of voltage-gated K(+) channels, which are regulated by both PIP2 and PUFAs and play a variety of important roles in human health and disease. This article is part of a Special Issue entitled: Lipid order/lipid defects and lipid-control of protein activity edited by Dirk Schneider.
PMID: 27818172 [PubMed - indexed for MEDLINE]
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Language and False-Belief Task Performance in Children With Autism Spectrum Disorder
Purpose
Language is related to false-belief (FB) understanding in both typically developing children and children with autism spectrum disorder (ASD). The current study examined the role of complementation and general language in FB understanding. Of interest was whether language plays similar or different roles in the groups' FB performance.
Method
Participants were 16 typically developing children (mean age = 5.0 years; mental age = 6.7) and 18 with ASD (mean age = 7.3 years; mental age = 8.3). Children were administered FB and language tasks (say- and think-complements), receptive and expressive vocabulary tests, and relative clauses.
Results
When mental age and receptive and expressive vocabulary were used as separate covariates, the typical control group outperformed the children with ASD in FB task performance. Chi-square analyses indicated that passing both complementation tasks was linked to the FB understanding of children with ASD. Children with ASD who passed FB tasks all passed say- and think-complement tasks. However, some children in the control group were able to pass the FB tasks, even if they failed the say- and think-complement tasks.
Conclusion
The results indicate that children with ASD relied more on complement understanding to pass FB than typically developing children. Results are discussed regarding the developmental pathways for FB understanding.from #Audiology via ola Kala on Inoreader http://ift.tt/2u7sAUx
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Polysyllable Speech Accuracy and Predictors of Later Literacy Development in Preschool Children With Speech Sound Disorders
Purpose
The aim of this study was to determine if polysyllable accuracy in preschoolers with speech sound disorders (SSD) was related to known predictors of later literacy development: phonological processing, receptive vocabulary, and print knowledge. Polysyllables—words of three or more syllables—are important to consider because unlike monosyllables, polysyllables have been associated with phonological processing and literacy difficulties in school-aged children. They therefore have the potential to help identify preschoolers most at risk of future literacy difficulties.
Method
Participants were 93 preschool children with SSD from the Sound Start Study. Participants completed the Polysyllable Preschool Test (Baker, 2013) as well as phonological processing, receptive vocabulary, and print knowledge tasks.
Results
Cluster analysis was completed, and 2 clusters were identified: low polysyllable accuracy and moderate polysyllable accuracy. The clusters were significantly different based on 2 measures of phonological awareness and measures of receptive vocabulary, rapid naming, and digit span. The clusters were not significantly different on sound matching accuracy or letter, sound, or print concept knowledge.
Conclusions
The participants' poor performance on print knowledge tasks suggested that as a group, they were at risk of literacy difficulties but that there was a cluster of participants at greater risk—those with both low polysyllable accuracy and poor phonological processing.from #Audiology via ola Kala on Inoreader http://ift.tt/2tyioHI
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Oticon Expands Opn Options and Hearing Resources for Teens
Oticon (https://www.oticon.com/) has added DSL rationale and a new miniRITE-T with telecoil for FM access to their Opn products for teenage hearing aid users, which they tout as their best assistive technology option for this population. The wireless technology featured in the discreet miniRITE-T design with a telecoil and double-push button can be used wherever a loop system is installed, and delivers sound directly to the users' hearing aids. The Oticon Opn is equipped with an OpenSound Navigator, which provides an open sound experience, allowing its user to focus on a conversation while staying attentive to people and things around them so they can switch focus quickly and easily. Teenage users can also connect to their favorite devices like their iPhones for direct streaming via their Bluetooth-enabled Opn hearing aids.
Oticon is also partnering with the Ida Institute to promote Telecare for Teens, a suite of easy-to-use online tools and resources that help teens self-mange and make more independent judgments about their hearing health care (http://ift.tt/2sZyZT8). These tools are designed for hearing care professionals to share with their teenage patients to help them prepare for appointments and make counseling more efficient. Audiologists can use these tools to identify communication needs and concerns and guide support for teens.
Published: 6/30/2017 10:10:00 AM
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Language and False-Belief Task Performance in Children With Autism Spectrum Disorder
Purpose
Language is related to false-belief (FB) understanding in both typically developing children and children with autism spectrum disorder (ASD). The current study examined the role of complementation and general language in FB understanding. Of interest was whether language plays similar or different roles in the groups' FB performance.
Method
Participants were 16 typically developing children (mean age = 5.0 years; mental age = 6.7) and 18 with ASD (mean age = 7.3 years; mental age = 8.3). Children were administered FB and language tasks (say- and think-complements), receptive and expressive vocabulary tests, and relative clauses.
Results
When mental age and receptive and expressive vocabulary were used as separate covariates, the typical control group outperformed the children with ASD in FB task performance. Chi-square analyses indicated that passing both complementation tasks was linked to the FB understanding of children with ASD. Children with ASD who passed FB tasks all passed say- and think-complement tasks. However, some children in the control group were able to pass the FB tasks, even if they failed the say- and think-complement tasks.
Conclusion
The results indicate that children with ASD relied more on complement understanding to pass FB than typically developing children. Results are discussed regarding the developmental pathways for FB understanding.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2u7sAUx
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Polysyllable Speech Accuracy and Predictors of Later Literacy Development in Preschool Children With Speech Sound Disorders
Purpose
The aim of this study was to determine if polysyllable accuracy in preschoolers with speech sound disorders (SSD) was related to known predictors of later literacy development: phonological processing, receptive vocabulary, and print knowledge. Polysyllables—words of three or more syllables—are important to consider because unlike monosyllables, polysyllables have been associated with phonological processing and literacy difficulties in school-aged children. They therefore have the potential to help identify preschoolers most at risk of future literacy difficulties.
Method
Participants were 93 preschool children with SSD from the Sound Start Study. Participants completed the Polysyllable Preschool Test (Baker, 2013) as well as phonological processing, receptive vocabulary, and print knowledge tasks.
Results
Cluster analysis was completed, and 2 clusters were identified: low polysyllable accuracy and moderate polysyllable accuracy. The clusters were significantly different based on 2 measures of phonological awareness and measures of receptive vocabulary, rapid naming, and digit span. The clusters were not significantly different on sound matching accuracy or letter, sound, or print concept knowledge.
Conclusions
The participants' poor performance on print knowledge tasks suggested that as a group, they were at risk of literacy difficulties but that there was a cluster of participants at greater risk—those with both low polysyllable accuracy and poor phonological processing.from #Audiology via xlomafota13 on Inoreader http://ift.tt/2tyioHI
via IFTTT
Language and False-Belief Task Performance in Children With Autism Spectrum Disorder
Purpose
Language is related to false-belief (FB) understanding in both typically developing children and children with autism spectrum disorder (ASD). The current study examined the role of complementation and general language in FB understanding. Of interest was whether language plays similar or different roles in the groups' FB performance.
Method
Participants were 16 typically developing children (mean age = 5.0 years; mental age = 6.7) and 18 with ASD (mean age = 7.3 years; mental age = 8.3). Children were administered FB and language tasks (say- and think-complements), receptive and expressive vocabulary tests, and relative clauses.
Results
When mental age and receptive and expressive vocabulary were used as separate covariates, the typical control group outperformed the children with ASD in FB task performance. Chi-square analyses indicated that passing both complementation tasks was linked to the FB understanding of children with ASD. Children with ASD who passed FB tasks all passed say- and think-complement tasks. However, some children in the control group were able to pass the FB tasks, even if they failed the say- and think-complement tasks.
Conclusion
The results indicate that children with ASD relied more on complement understanding to pass FB than typically developing children. Results are discussed regarding the developmental pathways for FB understanding.from #Audiology via ola Kala on Inoreader http://ift.tt/2u7sAUx
via IFTTT
Polysyllable Speech Accuracy and Predictors of Later Literacy Development in Preschool Children With Speech Sound Disorders
Purpose
The aim of this study was to determine if polysyllable accuracy in preschoolers with speech sound disorders (SSD) was related to known predictors of later literacy development: phonological processing, receptive vocabulary, and print knowledge. Polysyllables—words of three or more syllables—are important to consider because unlike monosyllables, polysyllables have been associated with phonological processing and literacy difficulties in school-aged children. They therefore have the potential to help identify preschoolers most at risk of future literacy difficulties.
Method
Participants were 93 preschool children with SSD from the Sound Start Study. Participants completed the Polysyllable Preschool Test (Baker, 2013) as well as phonological processing, receptive vocabulary, and print knowledge tasks.
Results
Cluster analysis was completed, and 2 clusters were identified: low polysyllable accuracy and moderate polysyllable accuracy. The clusters were significantly different based on 2 measures of phonological awareness and measures of receptive vocabulary, rapid naming, and digit span. The clusters were not significantly different on sound matching accuracy or letter, sound, or print concept knowledge.
Conclusions
The participants' poor performance on print knowledge tasks suggested that as a group, they were at risk of literacy difficulties but that there was a cluster of participants at greater risk—those with both low polysyllable accuracy and poor phonological processing.from #Audiology via ola Kala on Inoreader http://ift.tt/2tyioHI
via IFTTT
Oticon Expands Opn Options and Hearing Resources for Teens
Oticon (https://www.oticon.com/) has added DSL rationale and a new miniRITE-T with telecoil for FM access to their Opn products for teenage hearing aid users, which they tout as their best assistive technology option for this population. The wireless technology featured in the discreet miniRITE-T design with a telecoil and double-push button can be used wherever a loop system is installed, and delivers sound directly to the users' hearing aids. The Oticon Opn is equipped with an OpenSound Navigator, which provides an open sound experience, allowing its user to focus on a conversation while staying attentive to people and things around them so they can switch focus quickly and easily. Teenage users can also connect to their favorite devices like their iPhones for direct streaming via their Bluetooth-enabled Opn hearing aids.
Oticon is also partnering with the Ida Institute to promote Telecare for Teens, a suite of easy-to-use online tools and resources that help teens self-mange and make more independent judgments about their hearing health care (http://ift.tt/2sZyZT8). These tools are designed for hearing care professionals to share with their teenage patients to help them prepare for appointments and make counseling more efficient. Audiologists can use these tools to identify communication needs and concerns and guide support for teens.
Published: 6/30/2017 10:10:00 AM
from #Audiology via ola Kala on Inoreader http://ift.tt/2suGVIo
via IFTTT
Oticon Expands Opn Options and Hearing Resources for Teens
Oticon (https://www.oticon.com/) has added DSL rationale and a new miniRITE-T with telecoil for FM access to their Opn products for teenage hearing aid users, which they tout as their best assistive technology option for this population. The wireless technology featured in the discreet miniRITE-T design with a telecoil and double-push button can be used wherever a loop system is installed, and delivers sound directly to the users' hearing aids. The Oticon Opn is equipped with an OpenSound Navigator, which provides an open sound experience, allowing its user to focus on a conversation while staying attentive to people and things around them so they can switch focus quickly and easily. Teenage users can also connect to their favorite devices like their iPhones for direct streaming via their Bluetooth-enabled Opn hearing aids.
Oticon is also partnering with the Ida Institute to promote Telecare for Teens, a suite of easy-to-use online tools and resources that help teens self-mange and make more independent judgments about their hearing health care (http://ift.tt/2sZyZT8). These tools are designed for hearing care professionals to share with their teenage patients to help them prepare for appointments and make counseling more efficient. Audiologists can use these tools to identify communication needs and concerns and guide support for teens.
Published: 6/30/2017 10:10:00 AM
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Vanderbilt Audiology Journal Club - Bilateral Peripheral Vestibular System Impairment
A review of articles on the topic of bilateral vestibular hypofunction and failure. 
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Vanderbilt Audiology Journal Club - Bilateral Peripheral Vestibular System Impairment
A review of articles on the topic of bilateral vestibular hypofunction and failure.
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from #Audiology via ola Kala on Inoreader http://ift.tt/2txjPWF
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Vanderbilt Audiology Journal Club - Bilateral Peripheral Vestibular System Impairment
A review of articles on the topic of bilateral vestibular hypofunction and failure.
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Influence of Sex and Age on Posterior Semicircular Canal Thickness
Objective: The aim of this study is to determine whether sex and age influence posterior semicircular canal (PSC) thickness. Methods: This observational study was conducted in 3 tertiary hospitals. The minimal distance between the PSC and the posterior cranial fossa (PSC thickness) was estimated by thin-section multidetector row computed axial tomography (CAT) scan of the temporal bones. Nonselected consecutive patients of all ages (607 temporal bones) were considered. Results: A significant effect was only detected for sex (F = 5.418, p = 0.020); PSC thickness showed a higher mean value in women (mean difference ± SE: 0.224 ± 0.096 mm). A significant and negative r value was detected for males aged >45 years (-0.173, p = 0.026); in that group of patients, PSC thickness decreased as age increased (0.018 ± 0.008 mm/year). For females aged ≤45 years, a significant and positive r value was found (0.198, p = 0.022); in that group, PSC thickness increased as age increased (0.020 ± 0.008 mm/year). Conclusions: PSC thickness did not significantly evolve with age in young males (≤45 years) but it decreased from age 45 years onwards. On the other hand, PCS thickness increased with age in women until the age of 45 years and it did not significantly change in older females.
Audiol Neurotol 2017;22:56-59
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Audiol Neurotol 2017;22:56-59
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Medicine A
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Abstract Introduction: The key to successful treatment of OSAS is to individually tailor such treatment. Thus, it is very important to determine the severity of OSAS, its pattern, and the extent of collapse, by gender, age, and BMI. Objective: The objective of the study was to understand the characteristics...
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Abstract Introduction: Salivary gland tumors (SGTs) are rare head and neck malignancies consisting of a spectrum of tumors with different biological behaviors. Objective: In this study we aimed to find out differential expression of microRNA profiles between benign and malignant SGTs. Methods: We investigated...
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Abstract Introduction: The exact etiology of Bell's palsy still remains obscure. The only authenticated finding is inflammation and edema of the facial nerve leading to entrapment inside the facial canal. Objective: To identify if there is any relationship between the grade of Bell's palsy and diameter...
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Abstract Introduction: The management of laryngotracheal stenosis is complex and is influenced by multiple factors that can affect the ultimate outcome. Advanced lesions represent a special challenge to the treating surgeon to find the best remedying technique. Objective: To review the efficacy of our...
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Abstract Introduction: The proximity of the paranasal sinuses to the orbit and its contents allows the occurence of injuries in both primary or revision surgery. The majority of orbital complications are minor. The major complications are seen in 0.01-2.25% and some of them can be serious, leading to...
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Abstract Introduction: The chirp stimulus was developed seeking to counterbalance the delay of the sound wave on its journey through the cochlea, allowing the hair cells to depolarize at the same time. The result is a simultaneous stimulation providing better neural synchrony and, consequently, the recording...
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Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and...
15:57
Abstract Introduction: The vestibular evoked myogenic potential is a potential of mean latency that measures the muscle response to auditory stimulation. This potential can be generated from the contraction of the sternocleidomastoid muscle and also from the contraction of extraocular muscles in response...
15:57
Abstract Introduction: Although the incidence of Deep Cervical Abscess (DCA) has decreased mainly for the availability of antibiotics, this infection still occurs with considerable frequency and can be associated with high morbidity and mortality. Objective: This study aimed to present our clinical-surgical...
15:57
Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and...
15:57
Abstract Introduction: The large increase in the number of transnasal endoscopic skull base surgeries is a consequence of greater knowledge of the anatomic region, the development of specific materials and instruments, and especially the use of the nasoseptal flap as a barrier between the sinus tract...
15:57
Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and...
15:57
Abstract Introduction: The relationship between gastroesophageal reflux disease (GERD) and chronic rhinosinusitis (CRS) is still a controversial issue in literature. Objective: A systematic review of the association between these two diseases in adult patients. Methods: Systematic review in PubMed and...
15:56
Publication date: September 2017Source:Gait & Posture, Volume 57 Author(s): Kenji Tanimoto, Makoto Takahashi, Kazuki Tokuda, Tomonori Sawada, Masaya Anan, Koichi Shinkoda BackgroundDuring gait, the swing limb requires flexible control to adapt to ever changing environmental circumstances. However,...
15:55
Abstract Background Infant colic (IC) is a prevalent physiological event of infants, which can disrupt the child's home environment. We aimed to investigate the effectiveness of a mixture of Matricariae chamomilla L., Melissa officinalis L. and tyndallized Lactobacillus acidophilus (HA122) compared...
15:54
The online platform for Taylor & Francis Online content The American Journal of Bioethics, Volume 17, Issue 7, July 2017 is now available online on Taylor & Francis Online. This new issue contains the following articles: Guest Editorial Modernizing...
15:53
A systematic soil survey of Belgium was conducted from 1948 to 1991. Field surveys were done at the detailed scale of 1:5000 with the final maps published at a 1:20,000 scale. The legend of these detailed soil maps (scale 1:20,000) has been converted to the 3rd edition of the international soil classification...
15:51
Abstract Purpose of Review Sporotrichosis, the disease caused by Sporothrix spp, ranges from subcutaneous infections to the severe disseminated or invasive diseases. The taxonomy of Sporothrix has been revised. The subcutaneous disease is suspected easily, but the extra-cutaneous disease is diagnosed...
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We have recently demonstrated that mycobacterial ligands engage Toll like receptor 2 (TLR2) on CD4+ T cells and up-regulate T-cell receptor (TCR) triggered Th1 responses in vitro and in vivo. To better understand the role of T-cell expressed TLR2 on CD4+ T-cell differentiation and function, we conducted...
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Cell activation and apoptosis lead to the formation of extracellular vesicles (EVs) such as exosomes or microvesicles (MVs). EVs have been shown to modulate immune responses; recently, MVs were described to carry microRNA (miRNA) and a role for MVs in the pathogenesis of autoimmune diseases has been...
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Publication date: Available online 29 June 2017Source:Photodiagnosis and Photodynamic Therapy Author(s): Fernanda Belincanta Borghi-Pangoni, Mariana Volpato Junqueira, Sabrina Barbosa de Souza Ferreira, Larissa Lachi Silva, Bruno Ribeiro Rabello, Lidiane Vizioli de Castro, Mauro Luciano Baesso, Andréa...
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Abstract Background Dickkopf-4 (DKK4), a member of DKK family, appears to be a divergent protein. It remained multi-biological functions in carcinogenesis. The effect of DKK4 on the ovarian cancer cells remains unclear. This study...
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AbstractThe National Cancer Institute's Surveillance, Epidemiology, and End Results Program releases research files of cancer registry data. These files include geographic information at the county level, but no finer. Access to finer geography, such as census tract identifiers, would enable richer analyses—for...
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In the article "Associations of Accelerometry-Assessed and Self-Reported Physical Activity and Sedentary Behavior With All-Cause and Cardiovascular Mortality Among US Adults" by Evenson et al. (1), the units of measure for screen time were incorrectly listed as hours/week and MET-hours/week in Tables...
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AbstractBlack individuals have a lower risk of hearing loss than do whites, possibly because of differences in cochlear melanocytes. Previous studies have suggested that darker-skinned individuals tend to have more inner ear melanin, and cochlear melanocytes are important in generating the endocochlear...
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AbstractWe hypothesized that tumor necrosis factor receptor 1 (TNFR1) levels are associated with long-term trajectories of functional status independently of vascular risk factors and the occurrence of stroke and myocardial infarction (MI) during follow-up. In the Northern Manhattan Study, stroke-free...
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AbstractThe relationship between smoking and rosacea is poorly understood. We aimed to conduct the first cohort study to determine the association between smoking and risk of incident rosacea. We included 95,809 women from Nurses' Health Study II (1991–2005). Information on smoking was collected biennially...
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AbstractMany measures of chronic diseases, including respiratory disease, exhibit seasonal variation together with residual correlation between consecutive time periods and neighboring areas. We demonstrate a strategy for modeling data that exhibit both seasonal trend and spatiotemporal correlation,...
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AbstractThe role of obesity in adult asthma is well-known and has been partly attributed to a confounding role of physical inactivity. However, the interrelationships between obesity, physical activity, and asthma have been incompletely addressed, probably because their time-dependent and bidirectional...
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AbstractMaternal diabetes is associated with congenital heart defects (CHDs) as a group, but few studies have assessed risk for specific CHD phenotypes. We analyzed these relationships using data from the Texas Birth Defects Registry and statewide vital records for deliveries taking place in 1999–2009...
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In the article "Response and Follow-up Bias in Cohort Studies" by Greenland (1), there is a missing decimal point in the first footnote of Table 3. The risk ratio of 70 should be 0.70. from Cancer via xlomafota13 on Inoreader http://ift.tt/2trLoQR via IFTTT
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Publication date: Available online 29 June 2017Source:Allergology International Author(s): Isao OhnoSince the recognition of asthma as a syndrome with complex pathophysiological signs and symptoms, recent research has sought to classify asthma phenotypes based on its clinical and molecular pathological...
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Are you seeking additional training in the causes and mechanisms of atopic and contact dermatitis? Need to enhance your overall hands-on skills to accurately apply patch tests and interpret the results? Mark your calendar for the new, live course "Eczema and Contact Dermatitis in the Allergy/Immunology...
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Infection with respiratory syncytial virus (RSV) during infancy has been linked to increased risk for later onset of asthma. Additionally, prophylactic use within the first year of life of palivizumab, an mAb directed against the RSV fusion glycoprotein, protects against chronic wheezing through the...
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Advances in metagenomics, proteomics, metabolomics, and systems biology are providing a new emphasis in research; interdisciplinary work suggests that personalized medicine is on the horizon. These advances are illuminating sophisticated interactions between human-associated microbes and the immune system....
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Asthma prevalence has been on the increase, especially in North America compared with other continents. However, the prevalence of asthma differs worldwide, and in many countries the prevalence is stable or decreasing. This highlights the influence of environmental exposures, such as allergens, air pollution,...
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Perturbations or "dysbiosis" of the bronchial microbiota have been implicated in the pathogenesis of asthma. However, it remains unclear whether reported differences are reflective of atopy, a common comorbidity of asthma. In a National Heart, Lung, and Blood Institute AsthmaNet study of well-characterized...
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Our stewardship of the Journal of Allergy and Clinical Immunology (JACI) is now in its sophomore year.1 In this short time, we have had the privilege of working with our authors and readers and have endeavored to respond to your concerns and suggestions. We have instituted several changes in our quest...
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With regard to the article in the July 2016 issue entitled "Diminution of signal transducer and activator of transcription 3 signaling inhibits vascular permeability and anaphylaxis" (J Allergy Clin Immunol 2016;138:187-99), it has been brought to the Editors' attention that Fig 1 was incorrect as printed....
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Cells, Vol. 6, Pages 17: Standard Immunohistochemical Assays to Assess Autophagy in Mammalian Tissue
Autophagy is a highly conserved lysosomal degradation pathway with major impact on diverse human pathologies. Despite the development of different methodologies to detect autophagy both in vitro and in vivo, monitoring autophagy in tissue via immunohistochemical techniques is hampered due to the lack...
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Abstract Aim To determine the number of annual hospital discharges for inflammatory bowel diseases in Chile. The hypothesis is that there is a significant increase in the hospital discharges due to this disease from 2001 to 2012. Materials and Methods This is a descriptive study. Data were obtained...
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Abstract Background/Objectives Spitz nevi are melanocytic lesions with clinical, dermoscopic, and histopathologic presentations that may resemble those of melanoma. The evolution of Spitz nevi is a well-known feature. The objectives of this study were to investigate the clinical and dermoscopic...
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Photoresponsive blend films with post-crosslinked liquid crystalline polymer (CLCP) as a...
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Archives of Orthopaedic and Trauma Surgeryfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2tryi63
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St. Michael's Hospitalfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2s8Cp3f
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Archives of Physical Medicine and Rehabilitationfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2trgxno
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The American Journal of Surgeryfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2trGGCG
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International Journal of Cardiologyfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2s8FaBo
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The American Journal of Cardiologyfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2s8CuE5
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The American Journal of Emergency Medicinefrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2s98szM
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Current Orthopaedic Practicefrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2trFXBx
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Archives of Physical Medicine and Rehabilitationfrom Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2s8OJAu
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