Παρασκευή 3 Μαρτίου 2017
Phonak's Rechargeable Hearing Aid Wins International Design Award
The rechargeable hearing aid, Audéo B-R, by Phonak (https://www.phonak.com/) was recognized for its smart charging designs with the 2017 iF DESIGN AWARD. Audéo B-R was selected from 5,575 entries to receive the award in the product category by 58 independent experts from 19 countries. The iF panel of judges lauded the device's rechargeable features, which include a 30-minute charging option offering six hours of immediate use and a power pack that provides power for seven full charges for two hearing aids. Thomas Lang, senior vice president of marketing at Phonak, said, "The award underlines our efforts to pair the highest standards in hearing performance, ease of use, and innovation with outstanding design to help people with hearing loss live better lives."
The iF Design Award (http://ift.tt/1UbvApr) is given out by the iF International Forum Design GmbH in the product, communication and service design, architecture and interior architecture, and professional concepts categories. All award winners are featured in the iF WORLD DESIGN GUIDE, the iF design app, and are showcased at the iF design exhibition Hamburg.
Published: 3/3/2017 9:00:00 AM
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Phonak's Rechargeable Hearing Aid Wins International Design Award
The rechargeable hearing aid, Audéo B-R, by Phonak (https://www.phonak.com/) was recognized for its smart charging designs with the 2017 iF DESIGN AWARD. Audéo B-R was selected from 5,575 entries to receive the award in the product category by 58 independent experts from 19 countries. The iF panel of judges lauded the device's rechargeable features, which include a 30-minute charging option offering six hours of immediate use and a power pack that provides power for seven full charges for two hearing aids. Thomas Lang, senior vice president of marketing at Phonak, said, "The award underlines our efforts to pair the highest standards in hearing performance, ease of use, and innovation with outstanding design to help people with hearing loss live better lives."
The iF Design Award (http://ift.tt/1UbvApr) is given out by the iF International Forum Design GmbH in the product, communication and service design, architecture and interior architecture, and professional concepts categories. All award winners are featured in the iF WORLD DESIGN GUIDE, the iF design app, and are showcased at the iF design exhibition Hamburg.
Published: 3/3/2017 9:00:00 AM
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Phonak's Rechargeable Hearing Aid Wins International Design Award
The rechargeable hearing aid, Audéo B-R, by Phonak (https://www.phonak.com/) was recognized for its smart charging designs with the 2017 iF DESIGN AWARD. Audéo B-R was selected from 5,575 entries to receive the award in the product category by 58 independent experts from 19 countries. The iF panel of judges lauded the device's rechargeable features, which include a 30-minute charging option offering six hours of immediate use and a power pack that provides power for seven full charges for two hearing aids. Thomas Lang, senior vice president of marketing at Phonak, said, "The award underlines our efforts to pair the highest standards in hearing performance, ease of use, and innovation with outstanding design to help people with hearing loss live better lives."
The iF Design Award (http://ift.tt/1UbvApr) is given out by the iF International Forum Design GmbH in the product, communication and service design, architecture and interior architecture, and professional concepts categories. All award winners are featured in the iF WORLD DESIGN GUIDE, the iF design app, and are showcased at the iF design exhibition Hamburg.
Published: 3/3/2017 9:00:00 AM
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Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses.
| Related Articles |
Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses.
Neural Plast. 2017;2017:8283075
Authors: Wang C, Zhong Z, Sun P, Zhong H, Li H, Chen F
Abstract
The zebrafish has become an established model organism for the study of hearing and balance systems in the past two decades. The classical approach to examine hair cells is to use dye to conduct selective staining, which shows the number and morphology of hair cells but does not reveal their function. Startle response is a behavior closely related to the auditory function of hair cells; therefore it can be used to measure the function of hair cells. In this study, we developed a device to measure the startle response of zebrafish larvae. By applying various levels of stimulus, it showed that the system can discern a 10 dB difference. The hair cell in zebrafish can regenerate after damage due to noise exposure or drug treatment. With this device, we measured the startle response of zebrafish larvae during and after drug treatment. The results show a similar trend to the classical hair cell staining method. The startle response was reduced with drug treatment and recovered after removal of the drug. Together it demonstrated the capability of this behavioral assay in evaluating the hair cell functions of fish larvae and its potential as a high-throughput screening tool for auditory-related gene and drug discovery.
PMID: 28250994 [PubMed - in process]
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Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses.
| Related Articles |
Evaluation of the Hair Cell Regeneration in Zebrafish Larvae by Measuring and Quantifying the Startle Responses.
Neural Plast. 2017;2017:8283075
Authors: Wang C, Zhong Z, Sun P, Zhong H, Li H, Chen F
Abstract
The zebrafish has become an established model organism for the study of hearing and balance systems in the past two decades. The classical approach to examine hair cells is to use dye to conduct selective staining, which shows the number and morphology of hair cells but does not reveal their function. Startle response is a behavior closely related to the auditory function of hair cells; therefore it can be used to measure the function of hair cells. In this study, we developed a device to measure the startle response of zebrafish larvae. By applying various levels of stimulus, it showed that the system can discern a 10 dB difference. The hair cell in zebrafish can regenerate after damage due to noise exposure or drug treatment. With this device, we measured the startle response of zebrafish larvae during and after drug treatment. The results show a similar trend to the classical hair cell staining method. The startle response was reduced with drug treatment and recovered after removal of the drug. Together it demonstrated the capability of this behavioral assay in evaluating the hair cell functions of fish larvae and its potential as a high-throughput screening tool for auditory-related gene and drug discovery.
PMID: 28250994 [PubMed - in process]
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Cross-Cultural Adaptation and Validation of the Italian Version of the Voice Symptom Scale (I-VoiSS)
Source:Journal of Voice
Author(s): F. Mozzanica, C. Robotti, D. Ginocchio, C. Bulgheroni, R. Lorusso, M. Behlau, A. Schindler, F. Ottaviani
ObjectivesTo evaluate the reliability and validity of the Italian Voice Symptom Scale (I-VoiSS).Study DesignCross-sectional, nonrandomized, prospective study with controls.MethodsThe study consisted of five phases: item generation, reliability analysis, normative data generation, validity and responsiveness analysis. A group of 113 dysphonic patients was enrolled for the internal consistency analysis. Seventy-three of them completed the I-VoiSS twice, 2 weeks apart, for test-retest reliability analysis. A group of 150 vocally healthy participants completed the I-VoiSS for normative data generation. I-VoiSS scores obtained by dysphonic and vocally healthy participants were compared for validity analysis. I-VoiSS scores were correlated with those of the Italian version of the Voice Handicap Index (I-VHI) in 49 dysphonic patients for criterion validity analysis. I-VoiSS scores obtained in a group of 37 nonsmoker dysphonic patients before and after surgical treatment for vocal fold polyps were compared for responsiveness analysis. Finally, the cutoff value of the I-VoiSS was calculated.ResultsAll the enrolled participants managed to complete the I-VoiSS autonomously. Internal consistency and test-retest were satisfactory (α = 0.92 and r = 0.91). A significant difference in the I-VoiSS scores between the dysphonic and vocally healthy participants was found (p = 0.001). Positive significant correlations were found between I-VoiSS and I-VHI scores (r = 0.85). I-VoiSS scores obtained in the pretreatment condition were significantly higher than those obtained after surgery (p = 0.001). The cutoff value of I-VoiSS was 15.5.ConclusionI-VoiSS is reliable, valid, responsive to changes, and recommended for clinical practice and outcome research.
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A Review of Hyaluronic Acid and Hyaluronic Acid-based Hydrogels for Vocal Fold Tissue Engineering
Source:Journal of Voice
Author(s): Tanaya Walimbe, Alyssa Panitch, Preeti M. Sivasankar
Vocal fold scarring is a common cause of dysphonia. Current treatments involving vocal fold augmentation do not yield satisfactory outcomes in the long term. Tissue engineering and regenerative medicine offer an attractive treatment option for vocal fold scarring, with the aim to restore the native extracellular matrix microenvironment and biomechanical properties of the vocal folds by inhibiting progression of scarring and thus leading to restoration of normal vocal function. Hyaluronic acid is a bioactive glycosaminoglycan responsible for maintaining optimum viscoelastic properties of the vocal folds and hence is widely targeted in tissue engineering applications. This review covers advances in hyaluronic acid-based vocal fold tissue engineering and regeneration strategies.
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Investigation of the Effects of Speech Signal Length on Vocal Disorder Sorting Done Via Dynamic Pattern Modeling
Source:Journal of Voice
Author(s): Vida Mehdizadehfar, Farshad Almasganj, Farhad Torabinezhad
ObjectivesDevelopment of a noninvasive method for separating different vocal fold diseases is an important issue concerning vocal analysis. Due to the time variations along a pathologic vocal signal, application of dynamic pattern modeling tools is expected to help in the detection of defects that occur in the speech production mechanism.Materials and MethodsIn the present study, the hidden Markov model, which is a state space model, is employed to sort some of the vocal diseases. Moreover, this research mainly investigates the effects of the processed vocal signal lengths on the mentioned sorting task. To this end, the signal lengths of 1, 3, and 5 seconds of different disorders are used.ResultsThe experimental results show that some pathologic conditions in vocal folds such as cyst, false vocal cord, and mass are more evident in continued voice production, and the recognition accuracies gained via dynamic modeling of pathologic voice signals with more lengths are considerably improved.
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Walking-adaptability assessments with the Interactive Walkway: Between-systems agreement and sensitivity to task and subject variations
Publication date: Available online 2 March 2017
Source:Gait & Posture
Author(s): Daphne J. Geerse, Bert H. Coolen, Melvyn Roerdink
The ability to adapt walking to environmental circumstances is an important aspect of walking, yet difficult to assess. The Interactive Walkway was developed to assess walking adaptability by augmenting a multi-Kinect-v2 10-meter walkway with gait-dependent visual context (stepping targets, obstacles) using real-time processed markerless full-body kinematics. In this study we determined Interactive Walkway's usability for walking-adaptability assessments in terms of between-systems agreement and sensitivity to task and subject variations. Under varying task constraints, 21 healthy subjects performed obstacle-avoidance, sudden-stops-and-starts and goal-directed-stepping tasks. Various continuous walking-adaptability outcome measures were concurrently determined with the Interactive Walkway and a gold-standard motion-registration system: available response time, obstacle-avoidance and sudden-stop margins, step length, stepping accuracy and walking speed. The same holds for dichotomous classifications of success and failure for obstacle-avoidance and sudden-stops tasks and performed short-stride versus long-stride obstacle-avoidance strategies. Continuous walking-adaptability outcome measures generally agreed well between systems (high intraclass correlation coefficients for absolute agreement, low biases and narrow limits of agreement) and were highly sensitive to task and subject variations. Success and failure ratings varied with available response times and obstacle types and agreed between systems for 85-96% of the trials while obstacle-avoidance strategies were always classified correctly. We conclude that Interactive Walkway walking-adaptability outcome measures are reliable and sensitive to task and subject variations, even in high-functioning subjects. We therefore deem Interactive Walkway walking-adaptability assessments usable for obtaining an objective and more task-specific examination of one's ability to walk, which may be feasible for both high-functioning and fragile populations since walking adaptability can be assessed at various levels of difficulty.
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Source:Gait & Posture
Author(s): Daphne J. Geerse, Bert H. Coolen, Melvyn Roerdink
The ability to adapt walking to environmental circumstances is an important aspect of walking, yet difficult to assess. The Interactive Walkway was developed to assess walking adaptability by augmenting a multi-Kinect-v2 10-meter walkway with gait-dependent visual context (stepping targets, obstacles) using real-time processed markerless full-body kinematics. In this study we determined Interactive Walkway's usability for walking-adaptability assessments in terms of between-systems agreement and sensitivity to task and subject variations. Under varying task constraints, 21 healthy subjects performed obstacle-avoidance, sudden-stops-and-starts and goal-directed-stepping tasks. Various continuous walking-adaptability outcome measures were concurrently determined with the Interactive Walkway and a gold-standard motion-registration system: available response time, obstacle-avoidance and sudden-stop margins, step length, stepping accuracy and walking speed. The same holds for dichotomous classifications of success and failure for obstacle-avoidance and sudden-stops tasks and performed short-stride versus long-stride obstacle-avoidance strategies. Continuous walking-adaptability outcome measures generally agreed well between systems (high intraclass correlation coefficients for absolute agreement, low biases and narrow limits of agreement) and were highly sensitive to task and subject variations. Success and failure ratings varied with available response times and obstacle types and agreed between systems for 85-96% of the trials while obstacle-avoidance strategies were always classified correctly. We conclude that Interactive Walkway walking-adaptability outcome measures are reliable and sensitive to task and subject variations, even in high-functioning subjects. We therefore deem Interactive Walkway walking-adaptability assessments usable for obtaining an objective and more task-specific examination of one's ability to walk, which may be feasible for both high-functioning and fragile populations since walking adaptability can be assessed at various levels of difficulty.
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Within-assessor reliability and minimal detectable change of gait kinematics in a young obese demographic
Publication date: Available online 2 March 2017
Source:Gait & Posture
Author(s): Brian Horsak, Barbara Pobatschnig, Arnold Baca, Susanne Greber-Platzer, Alexandra Kreissl, Stefan Nehrer, Barbara Wondrasch, Richard Crevenna, Mohammad Keilani, Andreas Kranzl
IntroductionThree-dimensional gait analysis (3DGA) in obese populations is a difficult task due to a great amount of subcutaneous fat. This makes it more challenging to identify anatomical landmarks, thus leading to inconsistent marker placement. Therefore, the purpose of this study was to investigate the test-retest reliability for kinematic measurements of obese children and adolescents.MethodsNine males and two females with an age-based BMI above the 97th percentile (age: 14.6±2.6years, BMI: 33.4±4.4kg/m2) were administered to two 3DGA sessions. To quantify reliability of discrete parameters the intraclass correlation coefficient (ICC2,k), standard error of measurement (SEM) and minimal detectable change (MDC) were calculated. To quantify waveform similarity, the coefficient of multiple correlation (CMC) and the linear fit method (LFM) were used.ResultsFrom 28 kinematic parameters, 23 showed acceptable ICCs (≥0.70) and the remaining parameters demonstrated moderate values. These were peak hip extension during stance (0.58), mean pelvis rotation (0.60), mean anterior pelvic tilt (0.64), peak knee flexion during swing (0.67) and peak hip abduction during swing (0.69). The SEM was below 5° for all parameters. The MDC for the sagittal, frontal, and transversal plane were on average 7.5°±2.2, 4.6°±1.3 and 6.0°±0.9 respectively. Both the LFM and CMC showed, in general, moderate to good reliability except for pelvis tilt and hip rotation.ConclusionData demonstrated acceptable error margins especially for the sagittal and frontal plane. Low reliability for the pelvis tilt indicates that great effort is necessary to position the pelvic markers consistently during repeated sessions.
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Source:Gait & Posture
Author(s): Brian Horsak, Barbara Pobatschnig, Arnold Baca, Susanne Greber-Platzer, Alexandra Kreissl, Stefan Nehrer, Barbara Wondrasch, Richard Crevenna, Mohammad Keilani, Andreas Kranzl
IntroductionThree-dimensional gait analysis (3DGA) in obese populations is a difficult task due to a great amount of subcutaneous fat. This makes it more challenging to identify anatomical landmarks, thus leading to inconsistent marker placement. Therefore, the purpose of this study was to investigate the test-retest reliability for kinematic measurements of obese children and adolescents.MethodsNine males and two females with an age-based BMI above the 97th percentile (age: 14.6±2.6years, BMI: 33.4±4.4kg/m2) were administered to two 3DGA sessions. To quantify reliability of discrete parameters the intraclass correlation coefficient (ICC2,k), standard error of measurement (SEM) and minimal detectable change (MDC) were calculated. To quantify waveform similarity, the coefficient of multiple correlation (CMC) and the linear fit method (LFM) were used.ResultsFrom 28 kinematic parameters, 23 showed acceptable ICCs (≥0.70) and the remaining parameters demonstrated moderate values. These were peak hip extension during stance (0.58), mean pelvis rotation (0.60), mean anterior pelvic tilt (0.64), peak knee flexion during swing (0.67) and peak hip abduction during swing (0.69). The SEM was below 5° for all parameters. The MDC for the sagittal, frontal, and transversal plane were on average 7.5°±2.2, 4.6°±1.3 and 6.0°±0.9 respectively. Both the LFM and CMC showed, in general, moderate to good reliability except for pelvis tilt and hip rotation.ConclusionData demonstrated acceptable error margins especially for the sagittal and frontal plane. Low reliability for the pelvis tilt indicates that great effort is necessary to position the pelvic markers consistently during repeated sessions.
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