Σάββατο 21 Απριλίου 2018

Communication disorders in aging

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Current practice of ototoxicity management across the United Kingdom (UK)

.


from #Audiology via ola Kala on Inoreader https://ift.tt/2K6voce
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition

.


from #Audiology via ola Kala on Inoreader https://ift.tt/2F4R1WZ
via IFTTT

Communication disorders in aging

.


from #Audiology via ola Kala on Inoreader https://ift.tt/2JfHE9t
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK)

.


from #Audiology via ola Kala on Inoreader https://ift.tt/2K6voce
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition

.


from #Audiology via ola Kala on Inoreader https://ift.tt/2F4R1WZ
via IFTTT

Communication disorders in aging

.


from #Audiology via xlomafota13 on Inoreader https://ift.tt/2JfHE9t
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK)

.


from #Audiology via xlomafota13 on Inoreader https://ift.tt/2K6voce
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition

.


from #Audiology via xlomafota13 on Inoreader https://ift.tt/2F4R1WZ
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition.

Related Articles

Modernising speech audiometry: using a smartphone application to test word recognition.

Int J Audiol. 2018 Apr 20;:1-9

Authors: van Zyl M, Swanepoel W, Myburgh HC

Abstract
OBJECTIVE: This study aimed to develop and assess a method to measure word recognition abilities using a smartphone application (App) connected to an audiometer.
DESIGN: Word lists were recorded in South African English and Afrikaans. Analyses were conducted to determine the effect of hardware used for presentation (computer, compact-disc player, or smartphone) on the frequency content of recordings. An Android App was developed to enable presentation of recorded materials via a smartphone connected to the auxiliary input of the audiometer. Experiments were performed to test feasibility and validity of the developed App and recordings.
STUDY SAMPLE: Participants were 100 young adults (18-30 years) with pure tone thresholds ≤15 dB across the frequency spectrum (250-8000 Hz).
RESULTS: Hardware used for presentation had no significant effect on the frequency content of recordings. Listening experiments indicated good inter-list reliability for recordings in both languages, with no significant differences between scores on different lists at each of the tested intensities. Performance-intensity functions had slopes of 4.05%/dB for English and 4.75%/dB for Afrikaans lists at the 50% point.
CONCLUSIONS: The developed smartphone App constitutes a feasible and valid method for measuring word recognition scores, and can support standardisation and accessibility of recorded speech audiometry.

PMID: 29676598 [PubMed - as supplied by publisher]



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Communication disorders in aging.

Related Articles

Communication disorders in aging.

Int J Audiol. 2018 Apr 20;:1

Authors: Pillion J

PMID: 29676595 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2F8H6zK
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HRpds2
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition.

Related Articles

Modernising speech audiometry: using a smartphone application to test word recognition.

Int J Audiol. 2018 Apr 20;:1-9

Authors: van Zyl M, Swanepoel W, Myburgh HC

Abstract
OBJECTIVE: This study aimed to develop and assess a method to measure word recognition abilities using a smartphone application (App) connected to an audiometer.
DESIGN: Word lists were recorded in South African English and Afrikaans. Analyses were conducted to determine the effect of hardware used for presentation (computer, compact-disc player, or smartphone) on the frequency content of recordings. An Android App was developed to enable presentation of recorded materials via a smartphone connected to the auxiliary input of the audiometer. Experiments were performed to test feasibility and validity of the developed App and recordings.
STUDY SAMPLE: Participants were 100 young adults (18-30 years) with pure tone thresholds ≤15 dB across the frequency spectrum (250-8000 Hz).
RESULTS: Hardware used for presentation had no significant effect on the frequency content of recordings. Listening experiments indicated good inter-list reliability for recordings in both languages, with no significant differences between scores on different lists at each of the tested intensities. Performance-intensity functions had slopes of 4.05%/dB for English and 4.75%/dB for Afrikaans lists at the 50% point.
CONCLUSIONS: The developed smartphone App constitutes a feasible and valid method for measuring word recognition scores, and can support standardisation and accessibility of recorded speech audiometry.

PMID: 29676598 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HQWQua
via IFTTT

Communication disorders in aging.

Related Articles

Communication disorders in aging.

Int J Audiol. 2018 Apr 20;:1

Authors: Pillion J

PMID: 29676595 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2F8H6zK
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



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Bioinformatic Integration of Molecular Networks and Major Pathways Involved in Mice Cochlear and Vestibular Supporting Cells.

Related Articles

Bioinformatic Integration of Molecular Networks and Major Pathways Involved in Mice Cochlear and Vestibular Supporting Cells.

Front Mol Neurosci. 2018;11:108

Authors: Requena T, Gallego-Martinez A, Lopez-Escamez JA

Abstract
Background: Cochlear and vestibular epithelial non-hair cells (ENHCs) are the supporting elements of the cellular architecture in the organ of Corti and the vestibular neuroepithelium in the inner ear. Intercellular and cell-extracellular matrix interactions are essential to prevent an abnormal ion redistribution leading to hearing and vestibular loss. The aim of this study is to define the main pathways and molecular networks in the mouse ENHCs. Methods: We retrieved microarray and RNA-seq datasets from mouse epithelial sensory and non-sensory cells from gEAR portal (https://ift.tt/2HCyOW1) and obtained gene expression fold-change between ENHCs and non-epithelial cells (NECs) against HCs for each gene. Differentially expressed genes (DEG) with a log2 fold change between 1 and -1 were discarded. The remaining genes were selected to search for interactions using Ingenuity Pathway Analysis and STRING platform. Specific molecular networks for ENHCs in the cochlea and the vestibular organs were generated and significant pathways were identified. Results: Between 1723 and 1559 DEG were found in the mouse cochlear and vestibular tissues, respectively. Six main pathways showed enrichment in the supporting cells in both tissues: (1) "Inhibition of Matrix Metalloproteases"; (2) "Calcium Transport I"; (3) "Calcium Signaling"; (4) "Leukocyte Extravasation Signaling"; (5) "Signaling by Rho Family GTPases"; and (6) "Axonal Guidance Si". In the mouse cochlea, ENHCs showed a significant enrichment in 18 pathways highlighting "axonal guidance signaling (AGS)" (p = 4.37 × 10-8) and "RhoGDI Signaling" (p = 3.31 × 10-8). In the vestibular dataset, there were 20 enriched pathways in ENHCs, the most significant being "Leukocyte Extravasation Signaling" (p = 8.71 × 10-6), "Signaling by Rho Family GTPases" (p = 1.20 × 10-5) and "Calcium Signaling" (p = 1.20 × 10-5). Among the top ranked networks, the most biologically significant network contained the "auditory and vestibular system development and function" terms. We also found 108 genes showing tonotopic gene expression in the cochlear ENHCs. Conclusions: We have predicted the main pathways and molecular networks for ENHCs in the organ of Corti and vestibular neuroepithelium. These pathways will facilitate the design of molecular maps to select novel candidate genes for hearing or vestibular loss to conduct functional studies.

PMID: 29674954 [PubMed]



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Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HRpds2
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition.

Related Articles

Modernising speech audiometry: using a smartphone application to test word recognition.

Int J Audiol. 2018 Apr 20;:1-9

Authors: van Zyl M, Swanepoel W, Myburgh HC

Abstract
OBJECTIVE: This study aimed to develop and assess a method to measure word recognition abilities using a smartphone application (App) connected to an audiometer.
DESIGN: Word lists were recorded in South African English and Afrikaans. Analyses were conducted to determine the effect of hardware used for presentation (computer, compact-disc player, or smartphone) on the frequency content of recordings. An Android App was developed to enable presentation of recorded materials via a smartphone connected to the auxiliary input of the audiometer. Experiments were performed to test feasibility and validity of the developed App and recordings.
STUDY SAMPLE: Participants were 100 young adults (18-30 years) with pure tone thresholds ≤15 dB across the frequency spectrum (250-8000 Hz).
RESULTS: Hardware used for presentation had no significant effect on the frequency content of recordings. Listening experiments indicated good inter-list reliability for recordings in both languages, with no significant differences between scores on different lists at each of the tested intensities. Performance-intensity functions had slopes of 4.05%/dB for English and 4.75%/dB for Afrikaans lists at the 50% point.
CONCLUSIONS: The developed smartphone App constitutes a feasible and valid method for measuring word recognition scores, and can support standardisation and accessibility of recorded speech audiometry.

PMID: 29676598 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HQWQua
via IFTTT

Communication disorders in aging.

Related Articles

Communication disorders in aging.

Int J Audiol. 2018 Apr 20;:1

Authors: Pillion J

PMID: 29676595 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2F8H6zK
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HRpds2
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HRpds2
via IFTTT

Modernising speech audiometry: using a smartphone application to test word recognition.

Related Articles

Modernising speech audiometry: using a smartphone application to test word recognition.

Int J Audiol. 2018 Apr 20;:1-9

Authors: van Zyl M, Swanepoel W, Myburgh HC

Abstract
OBJECTIVE: This study aimed to develop and assess a method to measure word recognition abilities using a smartphone application (App) connected to an audiometer.
DESIGN: Word lists were recorded in South African English and Afrikaans. Analyses were conducted to determine the effect of hardware used for presentation (computer, compact-disc player, or smartphone) on the frequency content of recordings. An Android App was developed to enable presentation of recorded materials via a smartphone connected to the auxiliary input of the audiometer. Experiments were performed to test feasibility and validity of the developed App and recordings.
STUDY SAMPLE: Participants were 100 young adults (18-30 years) with pure tone thresholds ≤15 dB across the frequency spectrum (250-8000 Hz).
RESULTS: Hardware used for presentation had no significant effect on the frequency content of recordings. Listening experiments indicated good inter-list reliability for recordings in both languages, with no significant differences between scores on different lists at each of the tested intensities. Performance-intensity functions had slopes of 4.05%/dB for English and 4.75%/dB for Afrikaans lists at the 50% point.
CONCLUSIONS: The developed smartphone App constitutes a feasible and valid method for measuring word recognition scores, and can support standardisation and accessibility of recorded speech audiometry.

PMID: 29676598 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HQWQua
via IFTTT

Communication disorders in aging.

Related Articles

Communication disorders in aging.

Int J Audiol. 2018 Apr 20;:1

Authors: Pillion J

PMID: 29676595 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2F8H6zK
via IFTTT

Current practice of ototoxicity management across the United Kingdom (UK).

Related Articles

Current practice of ototoxicity management across the United Kingdom (UK).

Int J Audiol. 2018 Apr 20;:1-13

Authors: Maru D, Malky GA

Abstract
OBJECTIVE: Effective management of patients diagnosed with ototoxicity is needed to reduce hearing and balance damage which affects communication and life quality. Despite widespread recommendations to monitor and manage ototoxicity in an early and effective manner, there is limited evidence to support the actual implementation of these recommendations for affected patient groups in healthcare services across the UK with limited publications available. In this study, an online questionnaire analysed the current practice of ototoxicity management and patient pathways across the UK once the diagnosis of ototoxicity was confirmed, targeting Audiologists, ENTs/AVPs and GPs.
DESIGN: Qualitative Survey Study.
STUDY SAMPLE: A randomised sample of hearing services in the UK, including audiology departments; GP practices and local health settings were targeted with a total of 134 completed surveys.
RESULTS: About 72% reported the absence of ototoxicity management protocols within their centre. Results depicted great inconsistency and variation across the UK in ototoxicity management services provided, treatment modification, monitoring and referral pathways.
CONCLUSION: Developing and advocating national guidelines are intended not only to inform clinical decision making but to provide minimum standards of care in ototoxicity management and offer greater awareness and education to improve patients' quality of life.

PMID: 29676584 [PubMed - as supplied by publisher]



from #Audiology via ola Kala on Inoreader https://ift.tt/2HRpds2
via IFTTT