The National Health Service and the Department of Health in the United Kingdom have awarded the Action on Hearing Loss grant to Raj Ladher, PhD, to help him continue his work on protocadherin-15, which could be the key to unlocking a cure for hearing loss. The new funds will allow Ladher's group to understand if modified protocadherin-15 in the hair cells alters the way in which they respond to sound and how hair cells turn sound vibration information into electrical signals that the brain can process. Mutations in protocadherin-15, which is crucial in allowing the inner ear to detect sound and balance information, cause hearing loss. Ladher's research can therefore potentially suggest ways in which protocadherin-15 can be targeted to develop treatments for hearing loss.
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