Ketamine Tinnitus

Please note: the following information does not constitute professional medical advice, and is provided for general informational purposes only. Please speak to your doctor if you have tinnitus.

With one in five Americans suffering from chronic ringing in the ears, better known as tinnitus, there’s no doubt this is a condition that greatly affects millions of individuals each and every day. From preventing people from holding down a job or enjoying numerous activities with their family and friends, tinnitus is a condition that up until recently had few effective treatment options. However, based on recent research and clinical trials, it has been found that the antidepressant medication Ketamine has in many cases given tinnitus sufferers relief from their condition.

What is Ketamine?
Invented in 1962 as an anesthetic to be used in surgery, ketamine has been used as an antidepressant to help patients with severe depression. Able to block various neurotransmitters in the nervous system, the drug has gained acclaim in recent years for its ability to help those with tinnitus. In fact, when it comes to ketamine tinnitus sufferers have reported dramatic improvements in short periods of time. According to researchers at Texas A&M, when using ketamine tinnitus sufferers who have even the most severe cases report improvements. In many cases, this is thought to be due to the fact that many of the symptoms associated with depression and PTSD, such as pain and phantom noises, are also part of tinnitus.

How is Ketamine Used with Tinnitus Patients?
When using ketamine tinnitus patients usually have two choices as to how the medication will be administered. For some patients, this involves an injection directly into their ear, with the benefits often lasting several months. In other instances, patients choose to have a series of four to six IV infusions over a two-week period, which also provides relief lasting several months.

When Should Treatment Begin?
When deciding to use ketamine, patients should be aware that the sooner they begin treatment after experiencing tinnitus symptoms, the better the chances they will experience positive treatment results. According to most tinnitus experts involved in ketamine research, tinnitus patients who have had an onset of symptoms within the past year are the ideal candidates for ketamine treatments.

The Future of Ketamine Treatment
Due to some patients experiencing relief within 20 minutes of an injection or IV treatment, the future of ketamine treatment looks quite positive. However, as with any new type of medical treatment, much more research will be conducted before a final conclusion is reached. But for those suffering from tinnitus, these new treatments offer much hope for the years ahead.

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Gait and functionality of individuals with visual impairment who participate in sports

Publication date: Available online 30 March 2018
Source:Gait & Posture
Author(s): Edson Soares da Silva, Gabriela Fischer, Rodrigo Gomes da Rosa, Pedro Schons, Luísa Beatriz Trevisan Teixeira, Wouter Hoogkamer, Leonardo Alexandre Peyré-Tartaruga
BackgroundIndividuals with visual impairment (VI) have often been observed to walk slower than individuals with unimpaired vision. These observations might be confounded by typical low levels of physical activity and greater sedentary behavior in individuals with VI than the overall population.Research questionHere, we compared gait and balance measures between individuals with VI who participate in disability sports, and activity level matched sighted individuals.MethodsWe assessed static balance, anthropometry, self-selected walking speed, locomotion rehabilitation index, and lower limb muscular endurance; and applied physical activity level and fear of falling questionnaires.ResultsIndividuals with VI who participate in disability sports, self-selected a similar walking speed (1.29 ± 0.26 m/s) as active sighted individuals (1.39 ± 0.21 m/s). Locomotor rehabilitation index and muscular endurance of lower limbs were also similar between groups. Individuals with VI presented lower static balance (42.0 ± 17.0s) than the sighted control group (45.0 ± 0s) when the controls were tested with their eyes open. However, no difference was found when the controls were tested with their eyes closed (30.3 ± 17.0s). Furthermore, individuals with VI showed a greater fear of falling.SignificanceIn conclusion, individuals with VI who participate in disability sports, as goalball and football, walk with similar self-selected walking speeds as active sighted individuals, but have slightly worse static balance and fear of falling.



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Gait and functionality of individuals with visual impairment who participate in sports

Publication date: Available online 30 March 2018
Source:Gait & Posture
Author(s): Edson Soares da Silva, Gabriela Fischer, Rodrigo Gomes da Rosa, Pedro Schons, Luísa Beatriz Trevisan Teixeira, Wouter Hoogkamer, Leonardo Alexandre Peyré-Tartaruga
BackgroundIndividuals with visual impairment (VI) have often been observed to walk slower than individuals with unimpaired vision. These observations might be confounded by typical low levels of physical activity and greater sedentary behavior in individuals with VI than the overall population.Research questionHere, we compared gait and balance measures between individuals with VI who participate in disability sports, and activity level matched sighted individuals.MethodsWe assessed static balance, anthropometry, self-selected walking speed, locomotion rehabilitation index, and lower limb muscular endurance; and applied physical activity level and fear of falling questionnaires.ResultsIndividuals with VI who participate in disability sports, self-selected a similar walking speed (1.29 ± 0.26 m/s) as active sighted individuals (1.39 ± 0.21 m/s). Locomotor rehabilitation index and muscular endurance of lower limbs were also similar between groups. Individuals with VI presented lower static balance (42.0 ± 17.0s) than the sighted control group (45.0 ± 0s) when the controls were tested with their eyes open. However, no difference was found when the controls were tested with their eyes closed (30.3 ± 17.0s). Furthermore, individuals with VI showed a greater fear of falling.SignificanceIn conclusion, individuals with VI who participate in disability sports, as goalball and football, walk with similar self-selected walking speeds as active sighted individuals, but have slightly worse static balance and fear of falling.



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Gait and functionality of individuals with visual impairment who participate in sports

Publication date: Available online 30 March 2018
Source:Gait & Posture
Author(s): Edson Soares da Silva, Gabriela Fischer, Rodrigo Gomes da Rosa, Pedro Schons, Luísa Beatriz Trevisan Teixeira, Wouter Hoogkamer, Leonardo Alexandre Peyré-Tartaruga
BackgroundIndividuals with visual impairment (VI) have often been observed to walk slower than individuals with unimpaired vision. These observations might be confounded by typical low levels of physical activity and greater sedentary behavior in individuals with VI than the overall population.Research questionHere, we compared gait and balance measures between individuals with VI who participate in disability sports, and activity level matched sighted individuals.MethodsWe assessed static balance, anthropometry, self-selected walking speed, locomotion rehabilitation index, and lower limb muscular endurance; and applied physical activity level and fear of falling questionnaires.ResultsIndividuals with VI who participate in disability sports, self-selected a similar walking speed (1.29 ± 0.26 m/s) as active sighted individuals (1.39 ± 0.21 m/s). Locomotor rehabilitation index and muscular endurance of lower limbs were also similar between groups. Individuals with VI presented lower static balance (42.0 ± 17.0s) than the sighted control group (45.0 ± 0s) when the controls were tested with their eyes open. However, no difference was found when the controls were tested with their eyes closed (30.3 ± 17.0s). Furthermore, individuals with VI showed a greater fear of falling.SignificanceIn conclusion, individuals with VI who participate in disability sports, as goalball and football, walk with similar self-selected walking speeds as active sighted individuals, but have slightly worse static balance and fear of falling.



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Hearing What You See

A recent gif image has been circulating  where individual can report hearing a “thud” sound

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Loyola Medicine Marks 500th Cochlear Implant

Loyola Medicine reached a landmark feat with its 500^th cochlear implant surgery. A standard treatment for patients with hearing loss but do not benefit as much from hearing aids, cochlear implants (CIs) have been reported to improve the quality of life of recipients.

"Loyola Medicine has an adult population of CI recipients, the vast majority of whom present with progressive hearing loss ranging from several years to decades," shared Candace R. Blank, AuD, audiologist chief at Loyola Medicine. "We see patients who range in age from their late teens through their 90s, with expected co-morbidities including anxiety, depression, and social isolation."
 
Over 37.5 million American adults have reported some form of hearing difficulty—an issue that worsens with age and gets aggravated by factors like occupational noise and excessive listening to recreational sounds.
 
Hearing loss is also associated with increased health risks like depression and cognitive impairment. However, a recent study based on a large-scale NHIS survey has pointed to the gap in audiology referral of many adults who could benefit from a hearing test, hearing aids, and CIs (Hearing Journal. 2018;71(3):6). In fact, only 22 percent of CI candidates actually get the device, the study found.
 
"There is a lack of information and awareness of current guidelines for implantable solutions among the public as well as with primary care physicians," explained Blank. "The survey underscores the importance of the primary care physician in taking an active role in understanding the significant implications of hearing loss.It is extremely unfortunate that majority of people who could benefit from a CI are not directed to the proper avenues necessary to be evaluated."
 
But Loyola offers a different scene, being one of the busiest hearing centers in the Midwest. It is also one of the first centers to implant a hybrid system—a combination of a CI and a hearing aid.
 
"Loyola Medicine's successful CI program is directly related to the close relationship between our excellent audiology and neurotology team," Blank told The Hearing Journal. The 500^th CI surgery was done by John Leonetti, MD, one of Loyola's four otolaryngologists with expertise in this procedure. "Together we determine if someone is medically, audiologically, and holistically a candidate—even if the patient is 96 years old… We treat both the patient's body and soul."

Published: 3/30/2018 10:15:00 AM

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Loyola Medicine Marks 500th Cochlear Implant

Loyola Medicine reached a landmark feat with its 500^th cochlear implant surgery. A standard treatment for patients with hearing loss but do not benefit as much from hearing aids, cochlear implants (CIs) have been reported to improve the quality of life of recipients.

"Loyola Medicine has an adult population of CI recipients, the vast majority of whom present with progressive hearing loss ranging from several years to decades," shared Candace R. Blank, AuD, audiologist chief at Loyola Medicine. "We see patients who range in age from their late teens through their 90s, with expected co-morbidities including anxiety, depression, and social isolation."
 
Over 37.5 million American adults have reported some form of hearing difficulty—an issue that worsens with age and gets aggravated by factors like occupational noise and excessive listening to recreational sounds.
 
Hearing loss is also associated with increased health risks like depression and cognitive impairment. However, a recent study based on a large-scale NHIS survey has pointed to the gap in audiology referral of many adults who could benefit from a hearing test, hearing aids, and CIs (Hearing Journal. 2018;71(3):6). In fact, only 22 percent of CI candidates actually get the device, the study found.
 
"There is a lack of information and awareness of current guidelines for implantable solutions among the public as well as with primary care physicians," explained Blank. "The survey underscores the importance of the primary care physician in taking an active role in understanding the significant implications of hearing loss.It is extremely unfortunate that majority of people who could benefit from a CI are not directed to the proper avenues necessary to be evaluated."
 
But Loyola offers a different scene, being one of the busiest hearing centers in the Midwest. It is also one of the first centers to implant a hybrid system—a combination of a CI and a hearing aid.
 
"Loyola Medicine's successful CI program is directly related to the close relationship between our excellent audiology and neurotology team," Blank told The Hearing Journal. The 500^th CI surgery was done by John Leonetti, MD, one of Loyola's four otolaryngologists with expertise in this procedure. "Together we determine if someone is medically, audiologically, and holistically a candidate—even if the patient is 96 years old… We treat both the patient's body and soul."

Published: 3/30/2018 10:15:00 AM

from #Audiology via xlomafota13 on Inoreader https://ift.tt/2E7B29Y
via IFTTT

Loyola Medicine Marks 500th Cochlear Implant

Loyola Medicine reached a landmark feat with its 500^th cochlear implant surgery. A standard treatment for patients with hearing loss but do not benefit as much from hearing aids, cochlear implants (CIs) have been reported to improve the quality of life of recipients.

"Loyola Medicine has an adult population of CI recipients, the vast majority of whom present with progressive hearing loss ranging from several years to decades," shared Candace R. Blank, AuD, audiologist chief at Loyola Medicine. "We see patients who range in age from their late teens through their 90s, with expected co-morbidities including anxiety, depression, and social isolation."
 
Over 37.5 million American adults have reported some form of hearing difficulty—an issue that worsens with age and gets aggravated by factors like occupational noise and excessive listening to recreational sounds.
 
Hearing loss is also associated with increased health risks like depression and cognitive impairment. However, a recent study based on a large-scale NHIS survey has pointed to the gap in audiology referral of many adults who could benefit from a hearing test, hearing aids, and CIs (Hearing Journal. 2018;71(3):6). In fact, only 22 percent of CI candidates actually get the device, the study found.
 
"There is a lack of information and awareness of current guidelines for implantable solutions among the public as well as with primary care physicians," explained Blank. "The survey underscores the importance of the primary care physician in taking an active role in understanding the significant implications of hearing loss.It is extremely unfortunate that majority of people who could benefit from a CI are not directed to the proper avenues necessary to be evaluated."
 
But Loyola offers a different scene, being one of the busiest hearing centers in the Midwest. It is also one of the first centers to implant a hybrid system—a combination of a CI and a hearing aid.
 
"Loyola Medicine's successful CI program is directly related to the close relationship between our excellent audiology and neurotology team," Blank told The Hearing Journal. The 500^th CI surgery was done by John Leonetti, MD, one of Loyola's four otolaryngologists with expertise in this procedure. "Together we determine if someone is medically, audiologically, and holistically a candidate—even if the patient is 96 years old… We treat both the patient's body and soul."

Published: 3/30/2018 10:15:00 AM

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GeneReviews®

GeneReviews®

Book. 1993

Authors: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A

Abstract
CLINICAL CHARACTERISTICS: The spectrum of ASAH1-related disorders ranges from Farber disease (FD) to spinal muscular atrophy with progressive myoclonic epilepsy (SMA-PME). Classic FD is characterized by onset in the first weeks of life of painful, progressive deformity of the major joints; palpable subcutaneous nodules of joints and mechanical pressure points; and a hoarse cry resulting from granulomas of the larynx and epiglottis. Life expectancy is usually less than two years. In the other less common types of FD, onset, severity, and primary manifestations vary. SMA-PME is characterized by early-childhood-onset progressive lower motor neuron disease manifest typically between ages three and seven years as proximal lower-extremity weakness, followed by progressive myoclonic and atonic seizures, tremulousness/tremor, and sensorineural hearing loss. Myoclonic epilepsy typically begins in late childhood after the onset of weakness and can include jerking of the upper limbs, action myoclonus, myoclonic status, and eyelid myoclonus. Other findings include generalized tremor, and cognitive decline. The time from disease onset to death from respiratory complications is usually five to 15 years.
DIAGNOSIS/TESTING: The diagnosis of an ASAH1-related disorder is established in a proband with suggestive clinical findings by identification of biallelic pathogenic variants in ASAH1 and/or decreased activity of the enzyme acid ceramidase in peripheral blood leukocytes or cultured skin fibroblasts.
MANAGEMENT: Treatment of manifestations is symptomatic and multidisciplinary. For FD: Management may include gastrostomy tube placement, surgical removal of oral and airway granulomas, and treatment of seizures as per standard practice. Hematopoietic stem cell transplantation may be an option in affected individuals who do not have significant neurologic involvement. For SMA-PME: Management may include standard treatment for hearing loss, scoliosis, seizures, and tremor. Weakness can be mitigated with the use of orthotics, wheelchairs, or other assistive devices. Surveillance: For FD: At each visit assess growth with emphasis on feeding and nutritional status; airway, joint mobility, and developmental milestones. For SMA-PME: At each visit monitor growth with emphasis on feeding and nutritional status, pulmonary function, back for evidence of scoliosis, strength, seizure control, functional capacity (e.g., mobility, communication); assess hearing annually.
GENETIC COUNSELING: ASAH1-related disorders are inherited in an autosomal recessive manner. At conception, each sib of an affected individual has a 25% chance of being affected, a 50% chance of being an asymptomatic carrier, and a 25% chance of being unaffected and not a carrier. Sibs with the same two pathogenic variants would be expected to have the same (or very similar) phenotype. Once the ASAH1 pathogenic variants have been identified in an affected family member, carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk, and preimplantation genetic diagnosis are possible.

PMID: 29595935

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