A Profiling System for the Assessment of Individual Needs for Rehabilitation With Hearing Aids

This study focuses on the development of a profiling system to specify the needs of hearing-aid candidates. As a basis for the profile of compensation needs, we used a slightly modified version of the Amsterdam Inventory of Disability and Handicap, combined with the well-known Client-Oriented Scale of Improvement (COSI). The first questionnaire results in scores for six audiological dimensions: detection, speech in quiet, speech in noise, localization, focus or discrimination, and noise tolerance. The goal of this study was to determine whether the six dimensions derived from the disability questionnaire are appropriate to also categorize individual COSI targets. The results show a good agreement between eight audiologists in the categorization of COSI goals along the six dimensions. The results per dimension show that the dimension focus or discrimination can be regarded as superfluous. Possible additional dimensions were tinnitus and listening effort. The results indicate that it is possible to translate individual user needs (administered using COSI) into more general dimensions derived from a disability questionnaire. This allows to summarize the compensation needs for individual patients in a profile of general dimensions, based on the degree of disability and the individual user needs. This profile can be used as a starting point in hearing aid selection. This approach also offers a well-structured method for the evaluation of the postfitting results.

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Spectrotemporal Modulation Sensitivity as a Predictor of Speech-Reception Performance in Noise With Hearing Aids

The audiogram predicts <30% of the variance in speech-reception thresholds (SRTs) for hearing-impaired (HI) listeners fitted with individualized frequency-dependent gain. The remaining variance could reflect suprathreshold distortion in the auditory pathways or nonauditory factors such as cognitive processing. The relationship between a measure of suprathreshold auditory function—spectrotemporal modulation (STM) sensitivity—and SRTs in noise was examined for 154 HI listeners fitted with individualized frequency-specific gain. SRTs were measured for 65-dB SPL sentences presented in speech-weighted noise or four-talker babble to an individually programmed master hearing aid, with the output of an ear-simulating coupler played through insert earphones. Modulation-depth detection thresholds were measured over headphones for STM (2cycles/octave density, 4-Hz rate) applied to an 85-dB SPL, 2-kHz lowpass-filtered pink-noise carrier. SRTs were correlated with both the high-frequency (2–6 kHz) pure-tone average (HFA; R² = .31) and STM sensitivity (R² = .28). Combined with the HFA, STM sensitivity significantly improved the SRT prediction (R² = .13; total R² = .44). The remaining unaccounted variance might be attributable to variability in cognitive function and other dimensions of suprathreshold distortion. STM sensitivity was most critical in predicting SRTs for listeners < 65 years old or with HFA <53 dB HL. Results are discussed in the context of previous work suggesting that STM sensitivity for low rates and low-frequency carriers is impaired by a reduced ability to use temporal fine-structure information to detect dynamic spectra. STM detection is a fast test of suprathreshold auditory function for frequencies <2 kHz that complements the HFA to predict variability in hearing-aid outcomes for speech perception in noise.

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A Profiling System for the Assessment of Individual Needs for Rehabilitation With Hearing Aids

This study focuses on the development of a profiling system to specify the needs of hearing-aid candidates. As a basis for the profile of compensation needs, we used a slightly modified version of the Amsterdam Inventory of Disability and Handicap, combined with the well-known Client-Oriented Scale of Improvement (COSI). The first questionnaire results in scores for six audiological dimensions: detection, speech in quiet, speech in noise, localization, focus or discrimination, and noise tolerance. The goal of this study was to determine whether the six dimensions derived from the disability questionnaire are appropriate to also categorize individual COSI targets. The results show a good agreement between eight audiologists in the categorization of COSI goals along the six dimensions. The results per dimension show that the dimension focus or discrimination can be regarded as superfluous. Possible additional dimensions were tinnitus and listening effort. The results indicate that it is possible to translate individual user needs (administered using COSI) into more general dimensions derived from a disability questionnaire. This allows to summarize the compensation needs for individual patients in a profile of general dimensions, based on the degree of disability and the individual user needs. This profile can be used as a starting point in hearing aid selection. This approach also offers a well-structured method for the evaluation of the postfitting results.

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Spectrotemporal Modulation Sensitivity as a Predictor of Speech-Reception Performance in Noise With Hearing Aids

The audiogram predicts <30% of the variance in speech-reception thresholds (SRTs) for hearing-impaired (HI) listeners fitted with individualized frequency-dependent gain. The remaining variance could reflect suprathreshold distortion in the auditory pathways or nonauditory factors such as cognitive processing. The relationship between a measure of suprathreshold auditory function—spectrotemporal modulation (STM) sensitivity—and SRTs in noise was examined for 154 HI listeners fitted with individualized frequency-specific gain. SRTs were measured for 65-dB SPL sentences presented in speech-weighted noise or four-talker babble to an individually programmed master hearing aid, with the output of an ear-simulating coupler played through insert earphones. Modulation-depth detection thresholds were measured over headphones for STM (2cycles/octave density, 4-Hz rate) applied to an 85-dB SPL, 2-kHz lowpass-filtered pink-noise carrier. SRTs were correlated with both the high-frequency (2–6 kHz) pure-tone average (HFA; R² = .31) and STM sensitivity (R² = .28). Combined with the HFA, STM sensitivity significantly improved the SRT prediction (R² = .13; total R² = .44). The remaining unaccounted variance might be attributable to variability in cognitive function and other dimensions of suprathreshold distortion. STM sensitivity was most critical in predicting SRTs for listeners < 65 years old or with HFA <53 dB HL. Results are discussed in the context of previous work suggesting that STM sensitivity for low rates and low-frequency carriers is impaired by a reduced ability to use temporal fine-structure information to detect dynamic spectra. STM detection is a fast test of suprathreshold auditory function for frequencies <2 kHz that complements the HFA to predict variability in hearing-aid outcomes for speech perception in noise.

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A Profiling System for the Assessment of Individual Needs for Rehabilitation With Hearing Aids

This study focuses on the development of a profiling system to specify the needs of hearing-aid candidates. As a basis for the profile of compensation needs, we used a slightly modified version of the Amsterdam Inventory of Disability and Handicap, combined with the well-known Client-Oriented Scale of Improvement (COSI). The first questionnaire results in scores for six audiological dimensions: detection, speech in quiet, speech in noise, localization, focus or discrimination, and noise tolerance. The goal of this study was to determine whether the six dimensions derived from the disability questionnaire are appropriate to also categorize individual COSI targets. The results show a good agreement between eight audiologists in the categorization of COSI goals along the six dimensions. The results per dimension show that the dimension focus or discrimination can be regarded as superfluous. Possible additional dimensions were tinnitus and listening effort. The results indicate that it is possible to translate individual user needs (administered using COSI) into more general dimensions derived from a disability questionnaire. This allows to summarize the compensation needs for individual patients in a profile of general dimensions, based on the degree of disability and the individual user needs. This profile can be used as a starting point in hearing aid selection. This approach also offers a well-structured method for the evaluation of the postfitting results.

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Spectrotemporal Modulation Sensitivity as a Predictor of Speech-Reception Performance in Noise With Hearing Aids

The audiogram predicts <30% of the variance in speech-reception thresholds (SRTs) for hearing-impaired (HI) listeners fitted with individualized frequency-dependent gain. The remaining variance could reflect suprathreshold distortion in the auditory pathways or nonauditory factors such as cognitive processing. The relationship between a measure of suprathreshold auditory function—spectrotemporal modulation (STM) sensitivity—and SRTs in noise was examined for 154 HI listeners fitted with individualized frequency-specific gain. SRTs were measured for 65-dB SPL sentences presented in speech-weighted noise or four-talker babble to an individually programmed master hearing aid, with the output of an ear-simulating coupler played through insert earphones. Modulation-depth detection thresholds were measured over headphones for STM (2cycles/octave density, 4-Hz rate) applied to an 85-dB SPL, 2-kHz lowpass-filtered pink-noise carrier. SRTs were correlated with both the high-frequency (2–6 kHz) pure-tone average (HFA; R² = .31) and STM sensitivity (R² = .28). Combined with the HFA, STM sensitivity significantly improved the SRT prediction (R² = .13; total R² = .44). The remaining unaccounted variance might be attributable to variability in cognitive function and other dimensions of suprathreshold distortion. STM sensitivity was most critical in predicting SRTs for listeners < 65 years old or with HFA <53 dB HL. Results are discussed in the context of previous work suggesting that STM sensitivity for low rates and low-frequency carriers is impaired by a reduced ability to use temporal fine-structure information to detect dynamic spectra. STM detection is a fast test of suprathreshold auditory function for frequencies <2 kHz that complements the HFA to predict variability in hearing-aid outcomes for speech perception in noise.

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Extension of the clinical and molecular phenotype of DIAPH1-associated autosomal dominant hearing loss (DFNA1).

Extension of the clinical and molecular phenotype of DIAPH1-associated autosomal dominant hearing loss (DFNA1).

Clin Genet. 2016 Nov 3;:

Authors: Neuhaus C, Lang-Roth R, Zimmermann U, Heller R, Eisenberger T, Weikert M, Markus S, Knipper M, Bolz HJ

Abstract
In about 20% of non-syndromic hearing loss (NSHL) cases, inheritance is autosomal dominant (ADNSHL). DIAPH1 mutations define the ADNSHL locus DFNA1. We identified two new families with heterozygous truncating DIAPH1 mutations (p.Ala1210Serfs*31 and p.Arg1213*). In contrast to the extensively studied original DFNA1 family, hearing loss was not confined to low frequencies, but congenital manifestation and rapid progression were confirmed. In line with a recent unrelated study, we identified an association with thrombocytopenia, reclassifying DFNA1 as a syndrome. Consequently, we suggest to include the blood count into the initial clinical workup of patients with autosomal dominant hearing loss to guide the genetic diagnosis. We provide the first data on DIAPH1 expression in the organ of Corti, where it localizes to the inner pillar cells, at the base of the outer hair cells. Homozygous truncating DIAPH1 mutations located N-terminally to the DFNA1 mutations have recently been identified in autosomal recessive microcephaly. It is therefore noteworthy that we found DIAPH1 expression also in spiral ganglion neurons and in the barrier between the myelinating glia of the peripheral nervous system and oligodendrocytes that form the myelinating glia of the CNS.

PMID: 27808407 [PubMed - as supplied by publisher]

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The clinical features of osteogenesis imperfecta in Vietnam.

The clinical features of osteogenesis imperfecta in Vietnam.

Int Orthop. 2016 Nov 2;

Authors: Binh HD, Maasalu K, Dung VC, Ngoc CT, Hung TT, Nam TV, Nhan LN, Prans E, Reimann E, Zhytnik L, Kõks S, Märtson A

Abstract
PURPOSE: Osteogenesis imperfecta (OI) has not been studied in a Vietnamese population before. The aim of this study was to systematically collect epidemiological information, investigate clinical features and create a clinical database of OI patients in Vietnam for future research and treatment strategy development.
METHOD: Participants underwent clinical and physical examinations; also medical records were reviewed. Genealogical information was collected and family members' phenotypical manifestations recorded. Cases were classified according to the Sillence classification.
RESULTS: In total, 146 OI patients from 120 families were studied: 46 with OI Type I, 46 with Type III and 54 with Type IV. Almost patients had skeletal deformations. One hundred and forty-two had a history of fractures, 117 blue sclera, 89 dentinogenesis imperfecta and 26 hearing loss. The total number of fractures was 1,932. Thirty-four patients had intra-uterine fractures and nine had perinatal fractures. Surgery was performed 163 times in 58 patients; 100 osteosyntheses and 63 osteotomies. Bisphosphonate treatment was used in 37 patients. The number of affected individuals and predominance of severe forms of OI indicate that the disease is under diagnosed in Vietnam, especially in cases without a family history or with mild form of OI. Deformities appeared in all patients with different severity and localisation, affecting mostly the lower limbs. OI medical and surgical treatment rates are low and in most cases surgery was performed due to fractures.
CONCLUSIONS: Compared to previous studies, our results indicate a lower OI prevalence and greater severity of symptoms in the Vietnamese population when compared with other areas. Further investigation, improved diagnosis and treatment are needed to increase the patients' quality of life.

PMID: 27807717 [PubMed - as supplied by publisher]

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Mechanical Energy Patterns in Nordic Walking: Comparisons with Conventional Walking

Publication date: Available online 3 November 2016
Source:Gait & Posture
Author(s): Barbara Pellegrini, Leonardo Alexandre Peyré Tartaruga, Chiara Zoppirolli, Lorenzo Bortolan, Aldo Savoldelli, Alberto Enrico Minetti, Federico Schena
The use of poles during Nordic Walking (NW) actively engages the upper body to propel the body forward during walking. Evidence suggests that NW leads to a longer stride and higher speed, and sometimes to increased ground reaction forces with respect to conventional walking (W). The aim of this study was to investigate if NW is associated with different changes in body centre of mass (COM) motion and limbs energy patterns, mechanical work and efficiency compared to W. Eight experienced Nordic Walkers performed 5-minutes W and NW trials on a treadmill at 4km h-1. Steady state oxygen consumption and movements of body segments and poles were measured during each trial. We found greater fluctuation of kinetic (KE) and potential (PE) energy associated with COM displacement for NW compared to W. An earlier increase of KE for NW than for W, probably due to the propulsive action of poles, modified the synchronization between PE and KE oscillations so that a 10.9% higher pendular recovery between these energies was found in NW. The 10.2% higher total mechanical work found for NW was mainly due to the greater work required to move upper limbs and poles. NW was 20% less efficient and was metabolically more demanding than W, this difference could be ascribed to isometric contraction and low efficiency of upper musculature. Concluding, NW can be considered a highly dynamic gait, with distinctive mechanical features compared to conventional gait, due to pole propulsion and arm/pole swing.



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Mechanical Energy Patterns in Nordic Walking: Comparisons with Conventional Walking

Publication date: Available online 3 November 2016
Source:Gait & Posture
Author(s): Barbara Pellegrini, Leonardo Alexandre Peyré Tartaruga, Chiara Zoppirolli, Lorenzo Bortolan, Aldo Savoldelli, Alberto Enrico Minetti, Federico Schena
The use of poles during Nordic Walking (NW) actively engages the upper body to propel the body forward during walking. Evidence suggests that NW leads to a longer stride and higher speed, and sometimes to increased ground reaction forces with respect to conventional walking (W). The aim of this study was to investigate if NW is associated with different changes in body centre of mass (COM) motion and limbs energy patterns, mechanical work and efficiency compared to W. Eight experienced Nordic Walkers performed 5-minutes W and NW trials on a treadmill at 4km h-1. Steady state oxygen consumption and movements of body segments and poles were measured during each trial. We found greater fluctuation of kinetic (KE) and potential (PE) energy associated with COM displacement for NW compared to W. An earlier increase of KE for NW than for W, probably due to the propulsive action of poles, modified the synchronization between PE and KE oscillations so that a 10.9% higher pendular recovery between these energies was found in NW. The 10.2% higher total mechanical work found for NW was mainly due to the greater work required to move upper limbs and poles. NW was 20% less efficient and was metabolically more demanding than W, this difference could be ascribed to isometric contraction and low efficiency of upper musculature. Concluding, NW can be considered a highly dynamic gait, with distinctive mechanical features compared to conventional gait, due to pole propulsion and arm/pole swing.



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Mechanical Energy Patterns in Nordic Walking: Comparisons with Conventional Walking

Publication date: Available online 3 November 2016
Source:Gait & Posture
Author(s): Barbara Pellegrini, Leonardo Alexandre Peyré Tartaruga, Chiara Zoppirolli, Lorenzo Bortolan, Aldo Savoldelli, Alberto Enrico Minetti, Federico Schena
The use of poles during Nordic Walking (NW) actively engages the upper body to propel the body forward during walking. Evidence suggests that NW leads to a longer stride and higher speed, and sometimes to increased ground reaction forces with respect to conventional walking (W). The aim of this study was to investigate if NW is associated with different changes in body centre of mass (COM) motion and limbs energy patterns, mechanical work and efficiency compared to W. Eight experienced Nordic Walkers performed 5-minutes W and NW trials on a treadmill at 4km h-1. Steady state oxygen consumption and movements of body segments and poles were measured during each trial. We found greater fluctuation of kinetic (KE) and potential (PE) energy associated with COM displacement for NW compared to W. An earlier increase of KE for NW than for W, probably due to the propulsive action of poles, modified the synchronization between PE and KE oscillations so that a 10.9% higher pendular recovery between these energies was found in NW. The 10.2% higher total mechanical work found for NW was mainly due to the greater work required to move upper limbs and poles. NW was 20% less efficient and was metabolically more demanding than W, this difference could be ascribed to isometric contraction and low efficiency of upper musculature. Concluding, NW can be considered a highly dynamic gait, with distinctive mechanical features compared to conventional gait, due to pole propulsion and arm/pole swing.



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Virtual acoustic environments for comprehensive evaluation of model-based hearing devices

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Virtual acoustic environments for comprehensive evaluation of model-based hearing devices

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Virtual acoustic environments for comprehensive evaluation of model-based hearing devices

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Avoiding disconnection: An evaluation of telephone options for cochlear implant users

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Avoiding disconnection: An evaluation of telephone options for cochlear implant users

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Avoiding disconnection: An evaluation of telephone options for cochlear implant users

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Psychometric properties of the hearing handicap questionnaire: a Kannada (South-Indian) translation

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Psychometric properties of the hearing handicap questionnaire: a Kannada (South-Indian) translation

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Psychometric properties of the hearing handicap questionnaire: a Kannada (South-Indian) translation

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Vestibular Schwannoma Resection with Ipsilateral Simultaneous Cochlear Implantation in Patients with Normal Contralateral Hearing

Objective: To report the hearing results of cochlear implantation simultaneous to vestibular schwannoma (VS) resection by means of a translabyrinthine approach in patients with normal contralateral hearing. Methods: This was a prospective study including adults with sporadic VS. Tumors were resected by means of a modified translabyrinthine approach with preservation of the cochlear nerve. Results: A total of 13 patients underwent cochlear implantation. At 14 months, the mean pure-tone audiogram was 56 dB. The mean speech recognition was 80%. Cochlear implantation provides monaural and binaural benefits in all the conditions tested, including sound localization. Conclusions: Cochlear implantation can be safely performed simultaneously to VS resection with satisfactory hearing results provided that the cochlear nerve is anatomically intact.
Audiol Neurotol 2016;21:286-295

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