Publication date: February 2017
Source:Gait & Posture, Volume 52
Author(s): Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BackgroundThe ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions.MethodsA systematic literature search was conducted using PubMed, CINAHL, MEDLINE, PsycINFO, SCOPUS, Web of Science, and Cochrane Library (last search done in April 2016). The methodological quality was rated using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist.ResultsTwenty-three articles involving individuals with stroke, Parkinson’s disease, mild cognitive impairment, dementia, Alzheimer’s disease, and multiple sclerosis were included. Outcomes derived from the walking tasks under DT condition generally demonstrated good reliability (correlation coefficient ≥0.75) across different neurological disorders, but their usefulness in distinguishing fallers from non-fallers was inconclusive. The reliability of outcomes derived from the cognitive/motor tasks and from the dual-task effect (DTE) (i.e., DT performance minus single-task performance) seemed to be lower but was understudied. The reliability of static or dynamic sitting/standing balance outcomes in DT condition was not assessed in any of the selected studies.ConclusionsThe reliability of the outcomes derived from walking tasks was good. The psychometric properties of other DT outcomes need to be further investigated.
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Σάββατο 26 Νοεμβρίου 2016
Psychometric properties of dual-task balance and walking assessments for individuals with neurological conditions: A systematic review
Publication date: February 2017
Source:Gait & Posture, Volume 52
Author(s): Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BackgroundThe ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions.MethodsA systematic literature search was conducted using PubMed, CINAHL, MEDLINE, PsycINFO, SCOPUS, Web of Science, and Cochrane Library (last search done in April 2016). The methodological quality was rated using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist.ResultsTwenty-three articles involving individuals with stroke, Parkinson’s disease, mild cognitive impairment, dementia, Alzheimer’s disease, and multiple sclerosis were included. Outcomes derived from the walking tasks under DT condition generally demonstrated good reliability (correlation coefficient ≥0.75) across different neurological disorders, but their usefulness in distinguishing fallers from non-fallers was inconclusive. The reliability of outcomes derived from the cognitive/motor tasks and from the dual-task effect (DTE) (i.e., DT performance minus single-task performance) seemed to be lower but was understudied. The reliability of static or dynamic sitting/standing balance outcomes in DT condition was not assessed in any of the selected studies.ConclusionsThe reliability of the outcomes derived from walking tasks was good. The psychometric properties of other DT outcomes need to be further investigated.
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Source:Gait & Posture, Volume 52
Author(s): Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BackgroundThe ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions.MethodsA systematic literature search was conducted using PubMed, CINAHL, MEDLINE, PsycINFO, SCOPUS, Web of Science, and Cochrane Library (last search done in April 2016). The methodological quality was rated using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist.ResultsTwenty-three articles involving individuals with stroke, Parkinson’s disease, mild cognitive impairment, dementia, Alzheimer’s disease, and multiple sclerosis were included. Outcomes derived from the walking tasks under DT condition generally demonstrated good reliability (correlation coefficient ≥0.75) across different neurological disorders, but their usefulness in distinguishing fallers from non-fallers was inconclusive. The reliability of outcomes derived from the cognitive/motor tasks and from the dual-task effect (DTE) (i.e., DT performance minus single-task performance) seemed to be lower but was understudied. The reliability of static or dynamic sitting/standing balance outcomes in DT condition was not assessed in any of the selected studies.ConclusionsThe reliability of the outcomes derived from walking tasks was good. The psychometric properties of other DT outcomes need to be further investigated.
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Psychometric properties of dual-task balance and walking assessments for individuals with neurological conditions: A systematic review
Publication date: February 2017
Source:Gait & Posture, Volume 52
Author(s): Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BackgroundThe ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions.MethodsA systematic literature search was conducted using PubMed, CINAHL, MEDLINE, PsycINFO, SCOPUS, Web of Science, and Cochrane Library (last search done in April 2016). The methodological quality was rated using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist.ResultsTwenty-three articles involving individuals with stroke, Parkinson’s disease, mild cognitive impairment, dementia, Alzheimer’s disease, and multiple sclerosis were included. Outcomes derived from the walking tasks under DT condition generally demonstrated good reliability (correlation coefficient ≥0.75) across different neurological disorders, but their usefulness in distinguishing fallers from non-fallers was inconclusive. The reliability of outcomes derived from the cognitive/motor tasks and from the dual-task effect (DTE) (i.e., DT performance minus single-task performance) seemed to be lower but was understudied. The reliability of static or dynamic sitting/standing balance outcomes in DT condition was not assessed in any of the selected studies.ConclusionsThe reliability of the outcomes derived from walking tasks was good. The psychometric properties of other DT outcomes need to be further investigated.
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Source:Gait & Posture, Volume 52
Author(s): Lei Yang, Freddy Man Hin Lam, Lin Rong Liao, Mei Zhen Huang, Cheng Qi He, Marco Yiu Chung Pang
BackgroundThe ability of performing a balance or walking task in conjunction with a secondary cognitive or motor task, referred to as dual-task (DT) ability, is essential in daily living. While there is some evidence that DT performance is impaired in individuals with neurological conditions, using reliable and valid tools to measure DT performance is essential. This systematic review aimed to evaluate the psychometric properties of DT balance and walking assessments in individuals with different neurological conditions.MethodsA systematic literature search was conducted using PubMed, CINAHL, MEDLINE, PsycINFO, SCOPUS, Web of Science, and Cochrane Library (last search done in April 2016). The methodological quality was rated using the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist.ResultsTwenty-three articles involving individuals with stroke, Parkinson’s disease, mild cognitive impairment, dementia, Alzheimer’s disease, and multiple sclerosis were included. Outcomes derived from the walking tasks under DT condition generally demonstrated good reliability (correlation coefficient ≥0.75) across different neurological disorders, but their usefulness in distinguishing fallers from non-fallers was inconclusive. The reliability of outcomes derived from the cognitive/motor tasks and from the dual-task effect (DTE) (i.e., DT performance minus single-task performance) seemed to be lower but was understudied. The reliability of static or dynamic sitting/standing balance outcomes in DT condition was not assessed in any of the selected studies.ConclusionsThe reliability of the outcomes derived from walking tasks was good. The psychometric properties of other DT outcomes need to be further investigated.
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Spectral analysis of hearing protector impulsive insertion loss.
Spectral analysis of hearing protector impulsive insertion loss.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Fackler CJ, Berger EH, Murphy WJ, Stergar ME
Abstract
OBJECTIVE: To characterise the performance of hearing protection devices (HPDs) in impulsive-noise conditions and to compare various protection metrics between impulsive and steady-state noise sources with different characteristics.
DESIGN: HPDs were measured per the impulsive test methods of ANSI/ASA S12.42- 2010 . Protectors were measured with impulses generated by both an acoustic shock tube and an AR-15 rifle. The measured data were analysed for impulse peak insertion loss (IPIL) and impulsive spectral insertion loss (ISIL). These impulsive measurements were compared to insertion loss measured with steady-state noise and with real-ear attenuation at threshold (REAT).
STUDY SAMPLE: Tested HPDs included a foam earplug, a level-dependent earplug and an electronic sound-restoration earmuff.
RESULTS: IPIL for a given protector varied between measurements with the two impulse noise sources, but ISIL agreed between the two sources. The level-dependent earplug demonstrated level-dependent effects both in IPIL and ISIL. Steady-state insertion loss and REAT measurements tended to provide a conservative estimate of the impulsively-measured attenuation.
CONCLUSIONS: Measurements of IPIL depend strongly on the source used to measure them, especially for HPDs with less attenuation at low frequencies. ISIL provides an alternative measurement of impulse protection and appears to be a more complete description of an HPD's performance.
PMID: 27885881 [PubMed - as supplied by publisher]
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Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Sereda M, Davies J, Hall DA
Abstract
OBJECTIVE: This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus Sound Generator.
DESIGN: Open and closed questions addressed the following feasibility issues: (1) Participant recruitment; (2) Device acceptability; (3) Programme preferences in different self-nominated listening situations; (4) Usability; (5) Compliance; (6) Adverse events.
STUDY SAMPLE: Eight current combination hearing aid users (all males) aged between 62-72 years (mean age 67.25 years, SD = 3.8).
RESULTS: All eight participants reported the physical aspects and noise options on the experimental device to be acceptable. Programmes with amplification and masking features were equally preferred over the basic amplification-only programme. Individual preferences for the different programme options varied widely, both across participants and across listening situations.
CONCLUSIONS: A set of recommendations for future trials were formulated which calls for more "real world" trial design rather than tightly controlling the fitting procedure.
PMID: 27885869 [PubMed - as supplied by publisher]
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Functional Characterization of a Novel Loss-of-Function Mutation of PRPS1 related to Early-Onset Progressive Nonsyndromic Hearing Loss in Koreans (DFNX1): Potential Implications on Future Therapeutic Intervention.
Functional Characterization of a Novel Loss-of-Function Mutation of PRPS1 related to Early-Onset Progressive Nonsyndromic Hearing Loss in Koreans (DFNX1): Potential Implications on Future Therapeutic Intervention.
J Gene Med. 2016 Nov 25;:
Authors: Kim SY, Kim AR, Kim NK, Lee C, Han JH, Kim MY, Jeon EH, Park WY, Mittal R, Yan D, Liu XZ, Choi BY
Abstract
BACKGROUND: The symptoms of phosphoribosyl pyrophosphate synthetase 1 (PRPS1) deficiency diseases have been reported to be alleviated by medication. Herein, we report biochemical data to favor PRPS1 deficiency-related hearing loss as a potential target for pharmaceutical treatment.
METHODS: We recruited 42 probands from subjects under the age of 15 years with a moderate degree of nonsyndromic autosomal-recessive or sporadic sensorineural hearing loss (SNHL) in at least one side. Molecular genetic testing, including targeted exome sequencing (TES) of 129 deafness genes, and in silico prediction were performed.
RESULTS: A strong candidate variant-p.A82P-of PRPS1 is co-segregated with SNHL in X-linked recessive inheritance from one Korean multiplex SNHL family. Subsequent measurement of in vitro enzymatic activities of PRPS1 from erythrocytes of affected and unaffected family members as well as unrelated normal controls has confirmed a pathogenic role of this variant. In detail, compared with normal hearing controls (0.23 - 0.26 nmol/ml/h), the proband, affected sibling, and their normal hearing mother demonstrated a significantly decreased PRPS1 enzymatic activity (0.07, 0.03, and 0.11 nmol/ml/h, respectively). This novel loss-of-function mutation of PRPS1-p.A82P-is the 9(th) and 6(th) most reported mutation in the world and in Asia, respectively.
CONCLUSIONS: DFNX1 turned out to account for about 2.4% (1/42) of moderate SNHL in a Korean pediatric population. Confirmation of PRPS1 activity deficiency and an audiologic phenotype that initially begins in a milder form of SNHL, as in our family, should indicate the necessity for rigorous genetic screening as early as possible.
PMID: 27886419 [PubMed - as supplied by publisher]
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Spectral analysis of hearing protector impulsive insertion loss.
Spectral analysis of hearing protector impulsive insertion loss.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Fackler CJ, Berger EH, Murphy WJ, Stergar ME
Abstract
OBJECTIVE: To characterise the performance of hearing protection devices (HPDs) in impulsive-noise conditions and to compare various protection metrics between impulsive and steady-state noise sources with different characteristics.
DESIGN: HPDs were measured per the impulsive test methods of ANSI/ASA S12.42- 2010 . Protectors were measured with impulses generated by both an acoustic shock tube and an AR-15 rifle. The measured data were analysed for impulse peak insertion loss (IPIL) and impulsive spectral insertion loss (ISIL). These impulsive measurements were compared to insertion loss measured with steady-state noise and with real-ear attenuation at threshold (REAT).
STUDY SAMPLE: Tested HPDs included a foam earplug, a level-dependent earplug and an electronic sound-restoration earmuff.
RESULTS: IPIL for a given protector varied between measurements with the two impulse noise sources, but ISIL agreed between the two sources. The level-dependent earplug demonstrated level-dependent effects both in IPIL and ISIL. Steady-state insertion loss and REAT measurements tended to provide a conservative estimate of the impulsively-measured attenuation.
CONCLUSIONS: Measurements of IPIL depend strongly on the source used to measure them, especially for HPDs with less attenuation at low frequencies. ISIL provides an alternative measurement of impulse protection and appears to be a more complete description of an HPD's performance.
PMID: 27885881 [PubMed - as supplied by publisher]
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Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Sereda M, Davies J, Hall DA
Abstract
OBJECTIVE: This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus Sound Generator.
DESIGN: Open and closed questions addressed the following feasibility issues: (1) Participant recruitment; (2) Device acceptability; (3) Programme preferences in different self-nominated listening situations; (4) Usability; (5) Compliance; (6) Adverse events.
STUDY SAMPLE: Eight current combination hearing aid users (all males) aged between 62-72 years (mean age 67.25 years, SD = 3.8).
RESULTS: All eight participants reported the physical aspects and noise options on the experimental device to be acceptable. Programmes with amplification and masking features were equally preferred over the basic amplification-only programme. Individual preferences for the different programme options varied widely, both across participants and across listening situations.
CONCLUSIONS: A set of recommendations for future trials were formulated which calls for more "real world" trial design rather than tightly controlling the fitting procedure.
PMID: 27885869 [PubMed - as supplied by publisher]
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The Academy Research Grants in Hearing and Balance.
The Academy Research Grants in Hearing and Balance.
J Am Acad Audiol. 2016 Nov/Dec;27(10):788-789
Authors: Shinn J, McCaslin D
PMID: 27885974 [PubMed - in process]
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Spectral analysis of hearing protector impulsive insertion loss.
Spectral analysis of hearing protector impulsive insertion loss.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Fackler CJ, Berger EH, Murphy WJ, Stergar ME
Abstract
OBJECTIVE: To characterise the performance of hearing protection devices (HPDs) in impulsive-noise conditions and to compare various protection metrics between impulsive and steady-state noise sources with different characteristics.
DESIGN: HPDs were measured per the impulsive test methods of ANSI/ASA S12.42- 2010 . Protectors were measured with impulses generated by both an acoustic shock tube and an AR-15 rifle. The measured data were analysed for impulse peak insertion loss (IPIL) and impulsive spectral insertion loss (ISIL). These impulsive measurements were compared to insertion loss measured with steady-state noise and with real-ear attenuation at threshold (REAT).
STUDY SAMPLE: Tested HPDs included a foam earplug, a level-dependent earplug and an electronic sound-restoration earmuff.
RESULTS: IPIL for a given protector varied between measurements with the two impulse noise sources, but ISIL agreed between the two sources. The level-dependent earplug demonstrated level-dependent effects both in IPIL and ISIL. Steady-state insertion loss and REAT measurements tended to provide a conservative estimate of the impulsively-measured attenuation.
CONCLUSIONS: Measurements of IPIL depend strongly on the source used to measure them, especially for HPDs with less attenuation at low frequencies. ISIL provides an alternative measurement of impulse protection and appears to be a more complete description of an HPD's performance.
PMID: 27885881 [PubMed - as supplied by publisher]
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Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Sereda M, Davies J, Hall DA
Abstract
OBJECTIVE: This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus Sound Generator.
DESIGN: Open and closed questions addressed the following feasibility issues: (1) Participant recruitment; (2) Device acceptability; (3) Programme preferences in different self-nominated listening situations; (4) Usability; (5) Compliance; (6) Adverse events.
STUDY SAMPLE: Eight current combination hearing aid users (all males) aged between 62-72 years (mean age 67.25 years, SD = 3.8).
RESULTS: All eight participants reported the physical aspects and noise options on the experimental device to be acceptable. Programmes with amplification and masking features were equally preferred over the basic amplification-only programme. Individual preferences for the different programme options varied widely, both across participants and across listening situations.
CONCLUSIONS: A set of recommendations for future trials were formulated which calls for more "real world" trial design rather than tightly controlling the fitting procedure.
PMID: 27885869 [PubMed - as supplied by publisher]
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The Academy Research Grants in Hearing and Balance.
The Academy Research Grants in Hearing and Balance.
J Am Acad Audiol. 2016 Nov/Dec;27(10):788-789
Authors: Shinn J, McCaslin D
PMID: 27885974 [PubMed - in process]
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via IFTTT
Spectral analysis of hearing protector impulsive insertion loss.
Spectral analysis of hearing protector impulsive insertion loss.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Fackler CJ, Berger EH, Murphy WJ, Stergar ME
Abstract
OBJECTIVE: To characterise the performance of hearing protection devices (HPDs) in impulsive-noise conditions and to compare various protection metrics between impulsive and steady-state noise sources with different characteristics.
DESIGN: HPDs were measured per the impulsive test methods of ANSI/ASA S12.42- 2010 . Protectors were measured with impulses generated by both an acoustic shock tube and an AR-15 rifle. The measured data were analysed for impulse peak insertion loss (IPIL) and impulsive spectral insertion loss (ISIL). These impulsive measurements were compared to insertion loss measured with steady-state noise and with real-ear attenuation at threshold (REAT).
STUDY SAMPLE: Tested HPDs included a foam earplug, a level-dependent earplug and an electronic sound-restoration earmuff.
RESULTS: IPIL for a given protector varied between measurements with the two impulse noise sources, but ISIL agreed between the two sources. The level-dependent earplug demonstrated level-dependent effects both in IPIL and ISIL. Steady-state insertion loss and REAT measurements tended to provide a conservative estimate of the impulsively-measured attenuation.
CONCLUSIONS: Measurements of IPIL depend strongly on the source used to measure them, especially for HPDs with less attenuation at low frequencies. ISIL provides an alternative measurement of impulse protection and appears to be a more complete description of an HPD's performance.
PMID: 27885881 [PubMed - as supplied by publisher]
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Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial.
Int J Audiol. 2016 Nov 25;:1-9
Authors: Sereda M, Davies J, Hall DA
Abstract
OBJECTIVE: This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus Sound Generator.
DESIGN: Open and closed questions addressed the following feasibility issues: (1) Participant recruitment; (2) Device acceptability; (3) Programme preferences in different self-nominated listening situations; (4) Usability; (5) Compliance; (6) Adverse events.
STUDY SAMPLE: Eight current combination hearing aid users (all males) aged between 62-72 years (mean age 67.25 years, SD = 3.8).
RESULTS: All eight participants reported the physical aspects and noise options on the experimental device to be acceptable. Programmes with amplification and masking features were equally preferred over the basic amplification-only programme. Individual preferences for the different programme options varied widely, both across participants and across listening situations.
CONCLUSIONS: A set of recommendations for future trials were formulated which calls for more "real world" trial design rather than tightly controlling the fitting procedure.
PMID: 27885869 [PubMed - as supplied by publisher]
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