Several population-based epidemiological studies have demonstrated a relationship between physical activity and odds of hearing loss. However, these data to date have been limited to cross-sectional analyses, where cause and effect cannot be discerned. In a first study of physical activity on hearing loss in animals, Han et al. (2016) examined the impact of increased physical activity in mice (CBA/CaJ) on age-related hearing loss (ARHL). In the study, mice were divided into groups based on age and physical activity.
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