Promoting global action on hearing loss: World hearing day.

Related Articles

Promoting global action on hearing loss: World hearing day.

Int J Audiol. 2017 Mar;56(3):145-147

Authors: Chadha S, Cieza A

PMID: 28262049 [PubMed - in process]

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Promoting global action on hearing loss: World hearing day.

Related Articles

Promoting global action on hearing loss: World hearing day.

Int J Audiol. 2017 Mar;56(3):145-147

Authors: Chadha S, Cieza A

PMID: 28262049 [PubMed - in process]

from #Audiology via ola Kala on Inoreader http://ift.tt/2m0pPQv
via IFTTT

Promoting global action on hearing loss: World hearing day.

Related Articles

Promoting global action on hearing loss: World hearing day.

Int J Audiol. 2017 Mar;56(3):145-147

Authors: Chadha S, Cieza A

PMID: 28262049 [PubMed - in process]

from #Audiology via ola Kala on Inoreader http://ift.tt/2m0pPQv
via IFTTT

Promoting global action on hearing loss: World hearing day.

Related Articles

Promoting global action on hearing loss: World hearing day.

Int J Audiol. 2017 Mar;56(3):145-147

Authors: Chadha S, Cieza A

PMID: 28262049 [PubMed - in process]

from #Audiology via ola Kala on Inoreader http://ift.tt/2m0pPQv
via IFTTT

Asystole During Direct Laryngoscopy for Vocal Fold Injection in a Healthy Patient

Publication date: Available online 6 March 2017
Source:Journal of Voice
Author(s): Zahrah Taufique, Gregory R. Dion, Milan R. Amin
ObjectivesThis study aims (1) to present a case of asystole during direct laryngoscopy in an otherwise healthy patient at an outpatient surgery center and (2) to review literature on cardiac complications, specifically asystole and bradycardia, during direct laryngoscopy.MethodsA 67-year-old woman with no prior cardiac history underwent induction with succinylcholine and remifentanil for direct laryngoscopy and vocal fold augmentation. During suspension laryngoscopy, the patient became asystolic, and advanced care life support measures were started. The patient regained a cardiac rhythm after chest compressions and epinephrine and was transferred to a tertiary care hospital for further treatment. She remained intubated overnight, requiring pressors, and regained normal cardiac function over the next few days.ResultsA structured literature review uncovered few reports of asystole during suspension laryngoscopy. Although bradycardia is common during suspension laryngoscopy, likely secondary to stimulation of afferent visceral sensory parasympathetic fibers of the vagus nerve, asystole is rare.ConclusionsCardiac complications are possible in otolaryngologic surgery, especially with activation of the oculocardiac or trigeminocardiac reflexes. Asystole during direct laryngoscopy, although rare, is not always predictable from medicine or cardiac risk indices. Awareness, rapid recognition, and early implementation of advanced care life support are crucial to avoid further complications.



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Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.

Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.

Elife. 2017 Mar 06;6:

Authors: Bucks SA, Cox BC, Vlosich BA, Manning JP, Nguyen TB, Stone JS

Abstract
Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates. However, there is no definitive evidence that this process occurs in mammals. We used fate-mapping and other methods to demonstrate that utricular type II vestibular hair cells undergo turnover in adult mice under normal conditions. We found that supporting cells phagocytose both type I and II hair cells. Plp1-CreER(T2)-expressing supporting cells replace type II hair cells. Type I hair cells are not restored by Plp1-CreER(T2)-expressing supporting cells or by Atoh1-CreER(TM)-expressing type II hair cells. Destruction of hair cells causes supporting cells to generate 6 times as many type II hair cells compared to normal conditions. These findings expand our understanding of sensorineural plasticity in adult vestibular organs and further elucidate the roles that supporting cells serve during homeostasis and after injury.

PMID: 28263708 [PubMed - in process]

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Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.

Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice.

Elife. 2017 Mar 06;6:

Authors: Bucks SA, Cox BC, Vlosich BA, Manning JP, Nguyen TB, Stone JS

Abstract
Vestibular hair cells in the inner ear encode head movements and mediate the sense of balance. These cells undergo cell death and replacement (turnover) throughout life in non-mammalian vertebrates. However, there is no definitive evidence that this process occurs in mammals. We used fate-mapping and other methods to demonstrate that utricular type II vestibular hair cells undergo turnover in adult mice under normal conditions. We found that supporting cells phagocytose both type I and II hair cells. Plp1-CreER(T2)-expressing supporting cells replace type II hair cells. Type I hair cells are not restored by Plp1-CreER(T2)-expressing supporting cells or by Atoh1-CreER(TM)-expressing type II hair cells. Destruction of hair cells causes supporting cells to generate 6 times as many type II hair cells compared to normal conditions. These findings expand our understanding of sensorineural plasticity in adult vestibular organs and further elucidate the roles that supporting cells serve during homeostasis and after injury.

PMID: 28263708 [PubMed - in process]

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via IFTTT