Publication date: Available online 2 November 2016
Source:Hearing Research
Author(s): Garreth Prendergast, Hannah Guest, Kevin J. Munro, Karolina Kluk, Agnès Léger, Deborah A. Hall, Michael G. Heinz, Christopher J. Plack
Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies. In these animal models, the disorder is characterized by a reduction in amplitude of wave I of the auditory brainstem response (ABR) to high-level stimuli, whereas the response at threshold is unaffected. The aim of the present study was to determine if this disorder is prevalent in young adult humans with normal audiometric hearing. One hundred and twenty six participants (75 females) aged 18-36 were tested. Participants had a wide range of lifetime noise exposures as estimated by a structured interview. Audiometric thresholds did not differ across noise exposures up to 8 kHz, although 16-kHz audiometric thresholds were elevated with increasing noise exposure for females but not for males. ABRs were measured in response to high-pass (1.5 kHz) filtered clicks of 80 and 100 dB peSPL. Frequency-following responses (FFRs) were measured to 80 dB SPL pure tones from 240-285 Hz, and to 80 dB SPL 4 kHz pure tones amplitude modulated at frequencies from 240-285 Hz (transposed tones). The bandwidth of the ABR stimuli and the carrier frequency of the transposed tones were chosen to target the 3-6 kHz characteristic frequency region which is usually associated with noise damage in humans. The results indicate no relation between noise exposure and the amplitude of the ABR. In particular, wave I of the ABR did not decrease with increasing noise exposure as predicted. ABR wave V latency increased with increasing noise exposure for the 80 dB peSPL click. High carrier-frequency (envelope) FFR amplitudes decreased as a function of noise exposure in males but not females. However, these correlations were not significant after the effects of age were controlled. The results suggest either that noise-induced cochlear synaptopathy is not a significant problem in young, audiometrically normal adults, or that the ABR and FFR are relatively insensitive to this disorder in young humans, although it is possible that the effects become more pronounced with age.
from #Audiology via ola Kala on Inoreader http://ift.tt/2e6UcVd
via IFTTT
Πέμπτη 3 Νοεμβρίου 2016
Maturation of middle ear transmission in children
Source:Hearing Research
Author(s): Srikanta K. Mishra, Zoë Dinger, Lauren Renken
The goal of the current study was to characterize the normative features of wideband acoustic immittance in children for describing the functional maturation of the middle ear in 5 to 12-year-old children. Absorbance and group delay were measured in adults and three groups of children, 5–6, 7–9 and 10–12-year-olds, in a cross-sectional design. Absorbance showed significant effects of the age group in four out of ten center frequencies of one-half-octave bins from 211 to 6000 Hz, while there was no significant effect for group delay at any frequency. Older children (10–12 years) showed absorbance similar to adults. Test-retest reliability was high for absorbance for all age groups. However, group delay was modestly reliable only for adults. We conclude that the middle ear transmission follows a protracted period of maturation for high frequencies and reaches adult-like feature by 10 to 12 years of age.
from #Audiology via ola Kala on Inoreader http://ift.tt/2eF5zQr
via IFTTT
Effects of noise exposure on young adults with normal audiograms I: Electrophysiology
Publication date: Available online 2 November 2016
Source:Hearing Research
Author(s): Garreth Prendergast, Hannah Guest, Kevin J. Munro, Karolina Kluk, Agnès Léger, Deborah A. Hall, Michael G. Heinz, Christopher J. Plack
Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies. In these animal models, the disorder is characterized by a reduction in amplitude of wave I of the auditory brainstem response (ABR) to high-level stimuli, whereas the response at threshold is unaffected. The aim of the present study was to determine if this disorder is prevalent in young adult humans with normal audiometric hearing. One hundred and twenty six participants (75 females) aged 18-36 were tested. Participants had a wide range of lifetime noise exposures as estimated by a structured interview. Audiometric thresholds did not differ across noise exposures up to 8 kHz, although 16-kHz audiometric thresholds were elevated with increasing noise exposure for females but not for males. ABRs were measured in response to high-pass (1.5 kHz) filtered clicks of 80 and 100 dB peSPL. Frequency-following responses (FFRs) were measured to 80 dB SPL pure tones from 240-285 Hz, and to 80 dB SPL 4 kHz pure tones amplitude modulated at frequencies from 240-285 Hz (transposed tones). The bandwidth of the ABR stimuli and the carrier frequency of the transposed tones were chosen to target the 3-6 kHz characteristic frequency region which is usually associated with noise damage in humans. The results indicate no relation between noise exposure and the amplitude of the ABR. In particular, wave I of the ABR did not decrease with increasing noise exposure as predicted. ABR wave V latency increased with increasing noise exposure for the 80 dB peSPL click. High carrier-frequency (envelope) FFR amplitudes decreased as a function of noise exposure in males but not females. However, these correlations were not significant after the effects of age were controlled. The results suggest either that noise-induced cochlear synaptopathy is not a significant problem in young, audiometrically normal adults, or that the ABR and FFR are relatively insensitive to this disorder in young humans, although it is possible that the effects become more pronounced with age.
from #Audiology via ola Kala on Inoreader http://ift.tt/2e6UcVd
via IFTTT
Source:Hearing Research
Author(s): Garreth Prendergast, Hannah Guest, Kevin J. Munro, Karolina Kluk, Agnès Léger, Deborah A. Hall, Michael G. Heinz, Christopher J. Plack
Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies. In these animal models, the disorder is characterized by a reduction in amplitude of wave I of the auditory brainstem response (ABR) to high-level stimuli, whereas the response at threshold is unaffected. The aim of the present study was to determine if this disorder is prevalent in young adult humans with normal audiometric hearing. One hundred and twenty six participants (75 females) aged 18-36 were tested. Participants had a wide range of lifetime noise exposures as estimated by a structured interview. Audiometric thresholds did not differ across noise exposures up to 8 kHz, although 16-kHz audiometric thresholds were elevated with increasing noise exposure for females but not for males. ABRs were measured in response to high-pass (1.5 kHz) filtered clicks of 80 and 100 dB peSPL. Frequency-following responses (FFRs) were measured to 80 dB SPL pure tones from 240-285 Hz, and to 80 dB SPL 4 kHz pure tones amplitude modulated at frequencies from 240-285 Hz (transposed tones). The bandwidth of the ABR stimuli and the carrier frequency of the transposed tones were chosen to target the 3-6 kHz characteristic frequency region which is usually associated with noise damage in humans. The results indicate no relation between noise exposure and the amplitude of the ABR. In particular, wave I of the ABR did not decrease with increasing noise exposure as predicted. ABR wave V latency increased with increasing noise exposure for the 80 dB peSPL click. High carrier-frequency (envelope) FFR amplitudes decreased as a function of noise exposure in males but not females. However, these correlations were not significant after the effects of age were controlled. The results suggest either that noise-induced cochlear synaptopathy is not a significant problem in young, audiometrically normal adults, or that the ABR and FFR are relatively insensitive to this disorder in young humans, although it is possible that the effects become more pronounced with age.
from #Audiology via ola Kala on Inoreader http://ift.tt/2e6UcVd
via IFTTT
Maturation of middle ear transmission in children
Source:Hearing Research
Author(s): Srikanta K. Mishra, Zoë Dinger, Lauren Renken
The goal of the current study was to characterize the normative features of wideband acoustic immittance in children for describing the functional maturation of the middle ear in 5 to 12-year-old children. Absorbance and group delay were measured in adults and three groups of children, 5–6, 7–9 and 10–12-year-olds, in a cross-sectional design. Absorbance showed significant effects of the age group in four out of ten center frequencies of one-half-octave bins from 211 to 6000 Hz, while there was no significant effect for group delay at any frequency. Older children (10–12 years) showed absorbance similar to adults. Test-retest reliability was high for absorbance for all age groups. However, group delay was modestly reliable only for adults. We conclude that the middle ear transmission follows a protracted period of maturation for high frequencies and reaches adult-like feature by 10 to 12 years of age.
from #Audiology via ola Kala on Inoreader http://ift.tt/2eF5zQr
via IFTTT
Effects of noise exposure on young adults with normal audiograms I: Electrophysiology
Publication date: Available online 2 November 2016
Source:Hearing Research
Author(s): Garreth Prendergast, Hannah Guest, Kevin J. Munro, Karolina Kluk, Agnès Léger, Deborah A. Hall, Michael G. Heinz, Christopher J. Plack
Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies. In these animal models, the disorder is characterized by a reduction in amplitude of wave I of the auditory brainstem response (ABR) to high-level stimuli, whereas the response at threshold is unaffected. The aim of the present study was to determine if this disorder is prevalent in young adult humans with normal audiometric hearing. One hundred and twenty six participants (75 females) aged 18-36 were tested. Participants had a wide range of lifetime noise exposures as estimated by a structured interview. Audiometric thresholds did not differ across noise exposures up to 8 kHz, although 16-kHz audiometric thresholds were elevated with increasing noise exposure for females but not for males. ABRs were measured in response to high-pass (1.5 kHz) filtered clicks of 80 and 100 dB peSPL. Frequency-following responses (FFRs) were measured to 80 dB SPL pure tones from 240-285 Hz, and to 80 dB SPL 4 kHz pure tones amplitude modulated at frequencies from 240-285 Hz (transposed tones). The bandwidth of the ABR stimuli and the carrier frequency of the transposed tones were chosen to target the 3-6 kHz characteristic frequency region which is usually associated with noise damage in humans. The results indicate no relation between noise exposure and the amplitude of the ABR. In particular, wave I of the ABR did not decrease with increasing noise exposure as predicted. ABR wave V latency increased with increasing noise exposure for the 80 dB peSPL click. High carrier-frequency (envelope) FFR amplitudes decreased as a function of noise exposure in males but not females. However, these correlations were not significant after the effects of age were controlled. The results suggest either that noise-induced cochlear synaptopathy is not a significant problem in young, audiometrically normal adults, or that the ABR and FFR are relatively insensitive to this disorder in young humans, although it is possible that the effects become more pronounced with age.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2e6UcVd
via IFTTT
Source:Hearing Research
Author(s): Garreth Prendergast, Hannah Guest, Kevin J. Munro, Karolina Kluk, Agnès Léger, Deborah A. Hall, Michael G. Heinz, Christopher J. Plack
Noise-induced cochlear synaptopathy has been demonstrated in numerous rodent studies. In these animal models, the disorder is characterized by a reduction in amplitude of wave I of the auditory brainstem response (ABR) to high-level stimuli, whereas the response at threshold is unaffected. The aim of the present study was to determine if this disorder is prevalent in young adult humans with normal audiometric hearing. One hundred and twenty six participants (75 females) aged 18-36 were tested. Participants had a wide range of lifetime noise exposures as estimated by a structured interview. Audiometric thresholds did not differ across noise exposures up to 8 kHz, although 16-kHz audiometric thresholds were elevated with increasing noise exposure for females but not for males. ABRs were measured in response to high-pass (1.5 kHz) filtered clicks of 80 and 100 dB peSPL. Frequency-following responses (FFRs) were measured to 80 dB SPL pure tones from 240-285 Hz, and to 80 dB SPL 4 kHz pure tones amplitude modulated at frequencies from 240-285 Hz (transposed tones). The bandwidth of the ABR stimuli and the carrier frequency of the transposed tones were chosen to target the 3-6 kHz characteristic frequency region which is usually associated with noise damage in humans. The results indicate no relation between noise exposure and the amplitude of the ABR. In particular, wave I of the ABR did not decrease with increasing noise exposure as predicted. ABR wave V latency increased with increasing noise exposure for the 80 dB peSPL click. High carrier-frequency (envelope) FFR amplitudes decreased as a function of noise exposure in males but not females. However, these correlations were not significant after the effects of age were controlled. The results suggest either that noise-induced cochlear synaptopathy is not a significant problem in young, audiometrically normal adults, or that the ABR and FFR are relatively insensitive to this disorder in young humans, although it is possible that the effects become more pronounced with age.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2e6UcVd
via IFTTT
Maturation of middle ear transmission in children
Source:Hearing Research
Author(s): Srikanta K. Mishra, Zoë Dinger, Lauren Renken
The goal of the current study was to characterize the normative features of wideband acoustic immittance in children for describing the functional maturation of the middle ear in 5 to 12-year-old children. Absorbance and group delay were measured in adults and three groups of children, 5–6, 7–9 and 10–12-year-olds, in a cross-sectional design. Absorbance showed significant effects of the age group in four out of ten center frequencies of one-half-octave bins from 211 to 6000 Hz, while there was no significant effect for group delay at any frequency. Older children (10–12 years) showed absorbance similar to adults. Test-retest reliability was high for absorbance for all age groups. However, group delay was modestly reliable only for adults. We conclude that the middle ear transmission follows a protracted period of maturation for high frequencies and reaches adult-like feature by 10 to 12 years of age.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2eF5zQr
via IFTTT
Vocal Range in the Speech of Users of Low-Dose Oral Contraceptives
Source:Journal of Voice
Author(s): Eliséa Maria Meurer, Andressa Dias Moura, Leila Rechenberg, Helena von Eye Corleta, Edison Capp
ObjectiveThe study aimed to investigate the vocal range of oral contraceptive (OC) users aged between 20 and 30 years.Study DesignThis is a cross-sectional study.MethodsForty-eight women aged 20–30 years who used low-dose OCs and 24 age-matched women who did not use oral monophasic contraceptives (w/oOC) were enrolled. Acoustic analysis was performed using the Motor Speech Profile program, Model 4341 (Kay Elemetrics Corp). Data were analyzed using generalized estimating equation.ResultsIn the w/oOC group, the highest vocal tones in the sentence uttered using exclamatory intonation were similar in the follicular phases of two cycles (F1: 289 ± 46 Hz; F2: 284 ± 61 Hz). In the luteal phase of the first cycle, the vocal tones were lower, whereas in the second cycle they were higher than the tones in both follicular phases (L1: 274 ± 42 Hz; L2: 291 ± 62 Hz) (P = 0.056). In the highest vocal tones of the same sentence uttered using exclamatory intonation, the OC group showed lower tones (284 ± 53 Hz) than the w/oOC group (298 ± 44 Hz) (P = 0.048). In the lowest vocal tones of utterances of joy, the OC group showed higher values (180 ± 39 Hz) than the w/oOC group (169 ± 44 Hz) (P = 0.024). The close proximity of the highest to the lowest values of utterances of joy in the OC group (321 ± 59 Hz and 180 ± 39 Hz), when related to the w/oOC group (338 ± 65 Hz and 169 ± 44 Hz), suggests a reduced vocal modulation.ConclusionsThe present findings demonstrate that the use of low-dose OCs influences the vocal range of women during menacme.
from #Audiology via xlomafota13 on Inoreader http://ift.tt/2fkdqoj
via IFTTT
Εγγραφή σε:
Αναρτήσεις (Atom)