Παρασκευή 24 Μαΐου 2019

Medicine by Alexandros G. Sfakianakis


Medical Specialities
Burden of antenatal depression and its risk factors in Indian settings: A systematic reviewPriyanka Arora, Bani Tamber AeriIndian Journal of Medical Specialities 2019 10(2):55-60According to the National Mental Health Survey-2016, one in every ten persons in India suffers from depression and anxiety, and 20% of these depressed Indians are pregnant women and new mothers. This systematic review was conducted to assess the burden of depression and risk factors associated with it among the Indian pregnant...
Αλέξανδρος Γ. Σφακιανάκης
1m
Therapeutic benefits of lenalidomide in hematological malignancies Mohammed Shafi Abdulsalam, Durai...
Therapeutic benefits of lenalidomide in hematological malignanciesMohammed Shafi Abdulsalam, Durai Mavalavan Vasudevan ManimoliyanIndian Journal of Medical Specialities 2019 10(2):61-65Lenalidomide is an immunomodulatory agent, which has action against most of the hematological malignancies. Apart from its immunomodulation, it has other properties such as antiproliferation and antiangiogenesis. It is not only effective in myelodysplastic syndromes and myeloma, recent studies show its effective action...
Αλέξανδρος Γ. Σφακιανάκης
2m
Readout-Segmented Echo-Planar DWI for the Detection of Cholesteatomas: Correlation with Surgical...
Readout-Segmented Echo-Planar DWI for the Detection of Cholesteatomas: Correlation with Surgical Validation [HEAD & NECK]Radio by Fischer, N., Schartinger, V. H., De.. - 33m ago Preview    AUTO POST  SAVE TO EVERNOTEBACKGROUND AND PURPOSE:MR imaging has become an important tool for the detection of cholesteatomas of the middle ear. Various diffusion-weighted imaging sequences are available and have shown promising results. This study aimed to evaluate readout-segmented echo-planar DWI for the...
Αλέξανδρος Γ. Σφακιανάκης
1h
Oral health-related quality of life following orthognathic surgery for class III correction its relationship...
Oral health-related quality of life following orthognathic surgery for class III correction its relationship with cephalometric changesInternational Journal of Oral & Maxillof.. by A. Geramy, A. Mazaheri Nazarifar, A.. - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEThe aim of this study was to investigate the cephalometric changes following orthognathic surgery for class III correction and to compare these with the changes in patient perceptions of their oral health-related quality of life (OHRQoL)....
Αλέξανδρος Γ. Σφακιανάκης
1h
The influence of masseter and temporalis sarcomere-length operating ranges as determined by laser...
The influence of masseter and temporalis sarcomere-length operating ranges as determined by laser diffraction on architectural estimates of muscle force and excursion in macaques (Macaca fascicularis and Macaca mulatta)Oral Biology - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 20 May 2019Source: Archives of Oral BiologyAuthor(s): Andrea B. Taylor, Claire E. Terhune, Christopher J. VinyardAbstractObjectiveDetermine sarcomere length (Ls) operating ranges of the superficial...
Αλέξανδρος Γ. Σφακιανάκης
1h
The role of Wnt7B in the mediation of dentinogenesis via the ERK1/2 pathway Oral Biology - 3d ago Preview...
The role of Wnt7B in the mediation of dentinogenesis via the ERK1/2 pathwayOral Biology - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 21 May 2019Source: Archives of Oral BiologyAuthor(s): Dian Chen, Fanyuan Yu, Fanzi Wu, Mingru Bai, Feng Lou, Xueyang Liao, Chenglin Wang, Ling YeAbstractObjectivesThis study investigates the role of Wnt7b in mouse dentin formation.DesignC57BL/6 mouse tooth germs at different developmental stages were collected to measure the expression...
Αλέξανδρος Γ. Σφακιανάκης
1h
Oral health-related quality of life following orthognathic surgery for class III correction its relationship...
Oral health-related quality of life following orthognathic surgery for class III correction its relationship with cephalometric changesInternational Journal of Oral and Maxill.. - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 20 May 2019Source: International Journal of Oral and Maxillofacial SurgeryAuthor(s): A. Geramy, A. Mazaheri Nazarifar, A. Saffar Shahroudi, S. SheikhzadehAbstractThe aim of this study was to investigate the cephalometric changes following orthognathic...
Αλέξανδρος Γ. Σφακιανάκης
1h
Prevalence of distal surface caries in the second molar among referrals for assessment of third molars:...
Prevalence of distal surface caries in the second molar among referrals for assessment of third molars: a systematic review and meta-analysisBritish Journal of Oral and Maxillofacia.. by V. Toedtling, H. Devlin, M. Tickle,.. - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEWe conducted a systematic review of epidemiological studies to assess the prevalence of distal surface caries (DSC) in second molars adjacent to third molars. We searched the Cochrane Library, Lilacs, Embase, and Medline through...
Αλέξανδρος Γ. Σφακιανάκης
1h
Low-intensity pulsed ultrasound repair in mandibular condylar cartilage injury rabbit model Oral...
Low-intensity pulsed ultrasound repair in mandibular condylar cartilage injury rabbit modelOral Biology - 17h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: Archives of Oral BiologyAuthor(s): Hang-yu Zhou, Chi ZhangAbstractObjectivesBeneficial effects of low-intensity pulsed ultrasound(US) have been reported for knee articular cartilage injury. It is unclear whether the same effect could be observed on mandibular condylar cartilage. This study was...
Αλέξανδρος Γ. Σφακιανάκης
1h
Salivary and serum cystatin SA levels in patients with type 2 diabetes mellitus or diabetic nephropathy...
Salivary and serum cystatin SA levels in patients with type 2 diabetes mellitus or diabetic nephropathyOral Biology - 17h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: Archives of Oral BiologyAuthor(s): Suteera Techatanawat, Rudee Surarit, Kongthawat Chairatvit, Sittiruk Roytrakul, Weerapan Khovidhunkit, Supanee Thanakun, Yuichi Izumi, Siribang-on Piboonniyom KhovidhunkitAbstractObjectiveTo investigate putative salivary biomarkers for screening and...
Αλέξανδρος Γ. Σφακιανάκης
1h
Activity and distribution pattern of enzymes in the in-situ pellicle of children Oral Biology - 17h...
Activity and distribution pattern of enzymes in the in-situ pellicle of childrenOral Biology - 17h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: Archives of Oral BiologyAuthor(s): Susann Hertel, Annika Schulz, Roman Lang, Thomas Hofmann, Belinda König, Matthias Hannig, Christian HannigAbstractObjectiveThis study investigated, for the first time, pellicle enzymes with respect to their activity, distribution and fluorescence pattern in children with...
Αλέξανδρος Γ. Σφακιανάκης
1h
Staircase-pattern neonatal line in human deciduous teeth is associated with tooth type Oral Biology...
Staircase-pattern neonatal line in human deciduous teeth is associated with tooth typeOral Biology - 17h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: Archives of Oral BiologyAuthor(s): Jaana Hurnanen, Matti Sillanpää, Marja-Leena Mattila, Eliisa Löyttyniemi, Carsten Witzel, Jaana RautavaAbstractObjectiveThe staircase (Sc) pattern enamel microstructure is an expression of an impaired ameloblast function. It has been reported to appear in the neonatal...
Αλέξανδρος Γ. Σφακιανάκης
1h
Qualitative analysis on Crystal Growth of Synthetic Hydroxyapatite Influenced by Fluoride Concentration...
Qualitative analysis on Crystal Growth of Synthetic Hydroxyapatite Influenced by Fluoride ConcentrationOral Biology - 17h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 23 May 2019Source: Archives of Oral BiologyAuthor(s): Sumi Kang, Jeong Taeg Seo, Sung-Ho Park, Il Young Jung, Chan Young Lee, Jeong-Won ParkAbstractObjectiveThis study was designed to analyze the crystal growth of synthetic hydroxyapatite (HA) particles in pH 7.0 supersaturated solutions with different...
Αλέξανδρος Γ. Σφακιανάκης
1h
Novel endodontic sealer with dual strategies of dimethylaminohexadecyl methacrylate and nanoparticles...
Novel endodontic sealer with dual strategies of dimethylaminohexadecyl methacrylate and nanoparticles of silver to inhibit root canal biofilmsDental Materials - 12h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 23 May 2019Source: Dental MaterialsAuthor(s): Bashayer H. Baras, Mary Anne S. Melo, Jirun Sun, Thomas W. Oates, Michael D. Weir, Xianju Xie, Yuxing Bai, Hockin H.K. XuAbstractObjectiveEndodontic treatment failures and recontamination remain a major challenge....
Αλέξανδρος Γ. Σφακιανάκης
1h
Ionic liquid as antibacterial agent for an experimental orthodontic adhesive Dental Materials - 12h...
Ionic liquid as antibacterial agent for an experimental orthodontic adhesiveDental Materials - 12h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 23 May 2019Source: Dental MaterialsAuthor(s): Isadora Martini Garcia, Carolina Jung Ferreira, Virgínia Serra de Souza, Vicente Castelo Branco Leitune, Susana Maria Werner Samuel, Gabriela de Souza Balbinot, Amanda de Souza da Motta, Fernanda Visioli, Jackson Damiani Scholten, Fabrício Mezzomo CollaresAbstractObjectiveThe aim...
Αλέξανδρος Γ. Σφακιανάκης
1h
Management of anaemia and blood in patients having neck dissections or free flaps for head and neck...
Management of anaemia and blood in patients having neck dissections or free flaps for head and neck cancerBritish Journal of Oral and Maxillofacia.. by S.n. Rogers, K. Horisk, P. Groom, D.. - 7h ago Preview    AUTO POST  SAVE TO EVERNOTEOur main aims were to assess haemoglobin (Hb) concentrations from preoperative assessment to discharge from hospital, and to review which patients had blood transfusions and compliance with national transfusion guidelines. We studied a consecutive series of 131 patients...
Αλέξανδρος Γ. Σφακιανάκης
1h
Severe abdominal pain out of proportion to physical examination findings should be assumed to be AMI until disproven.Clinical scenario differentiates AMI as mesenteric arterial emboli, mesenteric arterial thrombosis, NOMI, or mesenteric venous thrombosis.
Acute mesenteric ischemia: guidelines of the World Society of Emergency SurgeryMiklosh BalaEmail author,Jeffry Kashuk,Ernest E. Moore,Yoram Kluger,Walter Biffl,Carlos Augusto Gomes,Offir Ben-Ishay,Chen Rubinstein,Zsolt J. Balogh,Ian Civil,Federico Coccolini,Ari Leppaniemi,Andrew Peitzman,Luca Ansaloni,Michael Sugrue,Massimo Sartelli,Salomone Di Saverio,Gustavo P. Fraga andFausto CatenaWorld Journal of Emergency Surgery201712:38https://doi.org/10.1186/s13017-017-0150-5©  The Author(s). 2017Received: 30 June 2017Accepted: 1 August 2017Published: 7 August 2017AbstractAcute...
Αλέξανδρος Γ. Σφακιανάκης
1h
Acute Mesenteric Ischaemia , ScienceDirect Publication: European Jour.. - 2d ago Preview     AUTO...
Acute Mesenteric Ischaemia,ScienceDirect Publication: European Jour.. - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Aurora N Lemma, Matti Tolonen, Pirkka Vikatmaa, Panu Mentula, Leena Vikatmaa, Ilkka Kantonen, Ari Leppäniemi, Ville SallinenObjectivesDespite modern advances in diagnosis and treatment, acute arterial mesenteric ischaemia (AMI) remains a high mortality disease. One...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Effect of Remote Ischaemic Preconditioning on Arterial Stiffness in Patients Undergoing Vascular...
The Effect of Remote Ischaemic Preconditioning on Arterial Stiffness in Patients Undergoing Vascular Surgery: A Randomised Clinical TrialScienceDirect Publication: European Jour.. - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Teele Kepler, Karl Kuusik, Urmas Lepner, Joel Starkopf, Mihkel Zilmer, Jaan Eha, Jüri Lieberg, Mare Vähi, Jaak KalsObjectivesThe main aim of this study was...
Αλέξανδρος Γ. Σφακιανάκης
1h
Revascularisations of Acute Limb Ischaemia , ScienceDirect Publication: European Jour.. - 12h ago Preview...
Revascularisations of Acute Limb Ischaemia,ScienceDirect Publication: European Jour.. - 12h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Christian-Alexander Behrendt, Martin Björck, Thea Schwaneberg, Eike S. Debus, Jack Cronenwett, Birgitta Sigvant, J. Earnshaw, K. Mani, S. Acosta, F. Cochennec, F.B. Goncalves, J.C. van den, H. Diener, H.C. Rieß, A. Gottsäter, R. Hinchliffe, V. Jongkind,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Abdominal Aortic Aneurysm , ScienceDirect Publication: European Jour.. - 12h ago Preview     AUTO...
Abdominal Aortic Aneurysm,ScienceDirect Publication: European Jour.. - 12h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 23 May 2019Source: European Journal of Vascular and Endovascular SurgeryAuthor(s): Sylvana M.L. de Mik, Reza Indrakusuma, Dink A. Legemate, Ron Balm, Dirk T. UbbinkObjectivesHigh-quality reporting of surgical risks is necessary for evidence-based risk communication in clinical practice. Risk communication is defined as the process of discussing benefits...
Αλέξανδρος Γ. Σφακιανάκης
1h
Optimization of Baccatin III Production by Cross-Linked Enzyme Aggregate of Taxoid 10β- O -Acetyltransferase...
Optimization of Baccatin III Production by Cross-Linked Enzyme Aggregate of Taxoid 10β- O -AcetyltransferaseLatest Results for Molecular Biotechnolo.. - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstractTaxoid 10β-O-acetyltransferase (DBAT) is the key enzyme to produce baccatin III, a key precursor in paclitaxel synthesis, by acetyl group transfer from acetyl-CoA to the C10 hydroxyl of 10-deacetylbaccatin III. In this study, the recombinant DBAT (rDBAT) was immobilized by cross-linked enzyme aggregates...
Αλέξανδρος Γ. Σφακιανάκης
1h
Dysphagia and Associated Pneumonia in Stroke Patients from Brazil: A Systematic Review Dysphagia...
Dysphagia and Associated Pneumonia in Stroke Patients from Brazil: A Systematic ReviewDysphagia - 4d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstractDysphagia and its associated complications are expected to be relatively more frequent in stroke patients in Brazil than in similar patients treated in developed countries due to the suboptimal stroke care in many Brazilians medical services. However, there is no estimate of dysphagia and pneumonia incidence for the overall stroke population in Brazil....
Αλέξανδρος Γ. Σφακιανάκης
1h
Evaluation of Thickened Fluids Used in Dysphagia Management Using Extensional Rheology Dysphagia...
Evaluation of Thickened Fluids Used in Dysphagia Management Using Extensional RheologyDysphagia - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstractRecent studies show that understanding the rheological properties of thickened fluids, such as viscosity and yield stress, is advantageous in designing optimal thickened fluids for the treatment of dysphagia. To date, these studies have focused on the rheological behavior of thickened fluids in shear deformation, while limited information is available...
Αλέξανδρος Γ. Σφακιανάκης
1h
Evaluation of Thickened Fluids Used in Dysphagia Management Using Extensional Rheology Dysphagia...
Evaluation of Thickened Fluids Used in Dysphagia Management Using Extensional RheologyDysphagia - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstractRecent studies show that understanding the rheological properties of thickened fluids, such as viscosity and yield stress, is advantageous in designing optimal thickened fluids for the treatment of dysphagia. To date, these studies have focused on the rheological behavior of thickened fluids in shear deformation, while limited information is available...
Αλέξανδρος Γ. Σφακιανάκης
1h
Successful non-surgical management of pleuroparenchymal fistula following cervical intraspinal empyema....
Successful non-surgical management of pleuroparenchymal fistula following cervical intraspinal empyema.Dysphagia - Rehabilitation - 3d ago Preview    AUTO POST  SAVE TO EVERNOTERelated ArticlesSuccessful non-surgical management of pleuroparenchymal fistula following cervical intraspinal empyema.Monaldi Arch Chest Dis. 2018 01 29;88(1):889Authors: Ull C, Aach M, Reichert J, Schildhauer TA, Swol JAbstractPulmonary infections are life-threatening complications in patients with spinal cord injuries....
Αλέξανδρος Γ. Σφακιανάκης
1h
The Effectiveness of a Multi-Disciplinary Intervention for Deglutition Disorders in Elderly Inpatients]....
The Effectiveness of a Multi-Disciplinary Intervention for Deglutition Disorders in Elderly Inpatients].Dysphagia - Rehabilitation - 3d ago Preview    AUTO POST  SAVE TO EVERNOTERelated Articles[The Effectiveness of a Multi-Disciplinary Intervention for Deglutition Disorders in Elderly Inpatients].Hu Li Za Zhi. 2018 Aug;65(4):73-83Authors: Chen Q, Guo JH, Xu XF, Zhou Y, Zhang Y, Hu XYAbstractBACKGROUND: While many studies have examined multidisciplinary interventions for swallowing disorder, most...
Αλέξανδρος Γ. Σφακιανάκης
1h
Intermittent Theta-Burst Stimulation Reverses the After-Effects of Contralateral Virtual Lesion on...
Intermittent Theta-Burst Stimulation Reverses the After-Effects of Contralateral Virtual Lesion on the Suprahyoid Muscle Cortex: Evidence From Dynamic Functional Connectivity Analysis.Dysphagia - Rehabilitation - 3d ago Preview    AUTO POST  SAVE TO EVERNOTERelated ArticlesIntermittent Theta-Burst Stimulation Reverses the After-Effects of Contralateral Virtual Lesion on the Suprahyoid Muscle Cortex: Evidence From Dynamic Functional Connectivity Analysis.Front Neurosci. 2019;13:309Authors: Zhang G,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Tongue function is important for masticatory performance in the healthy elderly: a cross-sectional...
Tongue function is important for masticatory performance in the healthy elderly: a cross-sectional survey of community-dwelling elderly.Dysphagia - Rehabilitation - 2d ago Preview    AUTO POST  SAVE TO EVERNOTERelated ArticlesTongue function is important for masticatory performance in the healthy elderly: a cross-sectional survey of community-dwelling elderly.J Prosthodont Res. 2019 Jan;63(1):31-34Authors: Sagawa K, Furuya H, Ohara Y, Yoshida M, Hirano H, Iijima K, Kikutani TAbstractPURPOSE: The...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cellular and Molecular Level Mechanisms against Electrochemical Cancer Therapy. Dysphagia - Rehabilitation...
Cellular and Molecular Level Mechanisms against Electrochemical Cancer Therapy.Dysphagia - Rehabilitation - 2d ago Preview    AUTO POST  SAVE TO EVERNOTERelated ArticlesCellular and Molecular Level Mechanisms against Electrochemical Cancer Therapy.J Pathog. 2019;2019:3431674Authors: Gu YH, Yamashita T, Inoue T, Song JH, Kang KMAbstractElectrochemical treatment (ECT) is a promising new way to induce tumor regression by flowing direct current into the cancer tissue. ECT was applied to different kinds...
Αλέξανδρος Γ. Σφακιανάκης
1h
¿Es posible la rediferenciación de NET tras la quimioterapia? Captación de imágenes de DOTA-péptidos...
¿Es posible la rediferenciación de NET tras la quimioterapia? Captación de imágenes de DOTA-péptidos marcados con 68Ga como cambio de estrategia en el tratamiento terapéuticoRevista Española de Medicina Nuclear e I.. - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 20 May 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): N. Ergül, T. Fikret Çermik, N. DursunResumenSe realizó una PET/TC con 68Ga DOTANOC a un varón de 64 años con tumor neuroendocrino...
Αλέξανδρος Γ. Σφακιανάκης
1h
Estudio comparativo de la PET/TC con 18F-FDG y la angiografía por TC en la detección de la vasculitis...
Estudio comparativo de la PET/TC con 18F-FDG y la angiografía por TC en la detección de la vasculitis de grandes vasosRevista Española de Medicina Nuclear e I.. - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 22 May 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): M. Moragas Solanes, M. Andreu Magarolas, J.C. Martín Miramon, A.P. Caresia Aróztegui, M. Monteagudo Jiménez, J.C. Oliva Morera, C. Diaz Martín, A. Rodríguez Revuelto, Z. Bravo...
Αλέξανδρος Γ. Σφακιανάκης
1h
Child sleep behaviors and sleep problems from infancy to school-age Sleep Medicine - 6d ago Preview...
Child sleep behaviors and sleep problems from infancy to school-ageSleep Medicine - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 18 May 2019Source: Sleep MedicineAuthor(s): Ariel A. Williamson, Jodi A. Mindell, Harriet Hiscock, Jon QuachAbstractObjectiveFew studies have examined the sleep behaviors associated with a caregiver-reported sleep problem beyond early childhood and across different age groups. This study examined sleep behaviors associated with a caregiver-reported...
Αλέξανδρος Γ. Σφακιανάκης
1h
Comparison of nocturnal pulse oximetry with polysomnography in children with sleep disordered breathing...
Comparison of nocturnal pulse oximetry with polysomnography in children with sleep disordered breathingLatest Results for Sleep and Breathing - 5d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract PurposePolysomnography (PSG) is the gold standard in the diagnosis of obstructive sleep apnea (OSA). However, due to high cost and limited availability, this is difficult to access and often delayed. To evaluate the reliability of overnight oximetry as a screening tool for OSA diagnosis.MethodAll children...
Αλέξανδρος Γ. Σφακιανάκης
1h
Comparison of nocturnal pulse oximetry with polysomnography in children with sleep disordered breathing...
Comparison of nocturnal pulse oximetry with polysomnography in children with sleep disordered breathingLatest Results for Sleep and Breathing - 5d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract PurposePolysomnography (PSG) is the gold standard in the diagnosis of obstructive sleep apnea (OSA). However, due to high cost and limited availability, this is difficult to access and often delayed. To evaluate the reliability of overnight oximetry as a screening tool for OSA diagnosis.MethodAll children...
Αλέξανδρος Γ. Σφακιανάκης
1h
The effect of body position on airway patency in obstructive sleep apnea: CT imaging analysis Latest...
The effect of body position on airway patency in obstructive sleep apnea: CT imaging analysisLatest Results for Sleep and Breathing - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract PurposePositional change during sleep influences upper airway patency. However, few studies have used imaging techniques to demonstrate the change. This study aims to determine the effect of positional change on the upper airway space.MethodsA total of 118 subjects with sleep breathing disorders were analyzed. Participants...
Αλέξανδρος Γ. Σφακιανάκης
1h
The prevalence of obstructive sleep apnoea in women with polycystic ovary syndrome: a systematic...
The prevalence of obstructive sleep apnoea in women with polycystic ovary syndrome: a systematic review and meta-analysisLatest Results for Sleep and Breathing - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract BackgroundObesity is a common risk factor for polycystic ovary syndrome (PCOS) and obstructive sleep apnoea (OSA). Both PCOS and OSA are associated with increased risk of type 2 diabetes and cardiovascular disease. Hence, it is important to determine the burden of OSA in women with PCOS.MethodsWe...
Αλέξανδρος Γ. Σφακιανάκης
1h
Adult sleep apnea and tonsil hypertrophy: should pharyngoplasty be associated with tonsillectomy?...
Adult sleep apnea and tonsil hypertrophy: should pharyngoplasty be associated with tonsillectomy?Latest Results for Sleep and Breathing - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract PurposeVelopharyngoplasty and palatine tonsillectomy are at the very heart of the surgical treatment of obstructive sleep apnea syndrome (OSAS) care. In cases of major tonsil hypertrophy, we evaluated the relevance of associating soft palate surgery with palatine tonsillectomy, independent of the soft palate...
Αλέξανδρος Γ. Σφακιανάκης
1h
Fas-positive lymphocytes are associated with systemic inflammation in obstructive sleep apnea syndrome...
Fas-positive lymphocytes are associated with systemic inflammation in obstructive sleep apnea syndromeLatest Results for Sleep and Breathing - 2d ago Preview    AUTO POST  SAVE TO EVERNOTEAbstract PurposeObstructive sleep apnea syndrome (OSAS) is associated with alterations in immune system which may lead to serious complications. The aim of this study was to explore lymphocyte populations in OSAS with special attention to the Fas-positive cells.MethodsFifty-one patients with confirmed OSA and 20...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cue-shifting between acoustic cues: Evidence for directional asymmetry ScienceDirect Publication...
Cue-shifting between acoustic cues: Evidence for directional asymmetryScienceDirect Publication Journal of Pho.. - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: July 2019Source: Journal of Phonetics, Volume 75Author(s): Meng Yang, Megha SundaraAbstractPrevious research shows that experience with co-varying cues is neither sufficient nor necessary for listeners to integrate them perceptually. Auditory Enhancement theorists explain this by positing that listeners integrate two cues...
Αλέξανδρος Γ. Σφακιανάκης
1h
Neurocognitive correlates of category ambiguous verb processing: The single versus dual lexical entry...
Neurocognitive correlates of category ambiguous verb processing: The single versus dual lexical entry hypothesesBrain Lang - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: July 2019Source: Brain and Language, Volume 194Author(s): Sladjana Lukic, Aya Meltzer-Asscher, James Higgins, Todd B. Parrish, Cynthia K. ThompsonAbstractWord-class ambiguous words engender greater processing time and fMRI (BOLD signal) activation than unambiguous ones. Theoretical accounts of this phenomenon suggest...
Αλέξανδρος Γ. Σφακιανάκης
1h
Voice Handicap Index-18 as an Instrument for Assessing Subjective Voice Impairment Between Voice...
Voice Handicap Index-18 as an Instrument for Assessing Subjective Voice Impairment Between Voice Pre- and Post-treatmentJournal of Voice Current Issue by Katharina Feige, Anne Strauss, Gero.. - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEThe Voice Handicap Index (VHI) is today regarded as the gold standard for measuring the subjective impairment of a voice disorder. The aim of our study is to present how the VHI in our version with 18 questions (VHI-18) can be evaluated with other patient collectives...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Usefulness of Auditory Perceptual Assessment and Acoustic Analysis for Classifying the Voice...
The Usefulness of Auditory Perceptual Assessment and Acoustic Analysis for Classifying the Voice SeverityJournal of Voice Current Issue by Yeonwoo Lee, Geunhyo Kim, Soonbok K.. - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEThe aims of this study were to (1) to determine the cut-off values of parameters related to auditory perceptual assessment (visual analog scale) and acoustic analysis (cepstral peak prominence, low frequency/high frequency ratio, cepstral peak prominence standard deviation, low...
Αλέξανδρος Γ. Σφακιανάκης
1h
Unsupervised-learning-based Keyphrase Extraction from a Single Document by the Effective Combination...
Unsupervised-learning-based Keyphrase Extraction from a Single Document by the Effective Combination of the Graph-based Model and the Modified C-value MethodScienceDirect Publication: Computer Spee.. - 6d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 17 May 2019Source: Computer Speech & LanguageAuthor(s): Hongseon Yeom, Youngjoong Ko, Jungyun SeoAbstractKeyphrases of a given document represent its main topic and they are used as a simple method to represent the...
Αλέξανδρος Γ. Σφακιανάκης
1h
Influence of coda stop features on perceived vowel duration ScienceDirect Publication Journal of...
Influence of coda stop features on perceived vowel durationScienceDirect Publication Journal of Pho.. - 5d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: July 2019Source: Journal of Phonetics, Volume 75Author(s): Chelsea SankerAbstractFour experiments tested what cues contribute to English speakers' perception of vowel duration. Listeners categorized the duration of vowels as 'long' or 'short' for stimuli produced with voiced, voiceless, breathy voiced, or voiceless aspirated stop codas....
Αλέξανδρος Γ. Σφακιανάκης
1h
Articulatory and Bottleneck Features for Speaker-Independent ASR of Dysarthric Speech ScienceDirect...
Articulatory and Bottleneck Features for Speaker-Independent ASR of Dysarthric SpeechScienceDirect Publication: Computer Spee.. - 5d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 18 May 2019Source: Computer Speech & LanguageAuthor(s): Emre Yılmaz, Vikramjit Mitra, Ganesh Sivaraman, Horacio FrancoAbstractThe rapid population aging has stimulated the development of assistive devices that provide personalized medical support to the needies suffering from various etiologies....
Αλέξανδρος Γ. Σφακιανάκης
1h
Phonological and Orthographic Reading Routes in French-Speaking Children with Severe Developmental...
Phonological and Orthographic Reading Routes in French-Speaking Children with Severe Developmental Language DisorderJournal of Communication Disorders (open.. - 3d ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 20 May 2019Source: Journal of Communication DisordersAuthor(s): Lucie Macchi, Séverine Casalis, Marie-Anne SchelstraeteAbstractPurposeThis study aims to assess written word recognition in French-speaking children with severe developmental language disorder (DLD),...
Αλέξανδρος Γ. Σφακιανάκης
1h
How Well Does Diadochokinetic Task Performance Predict Articulatory Imprecision? Differentiating...
How Well Does Diadochokinetic Task Performance Predict Articulatory Imprecision? Differentiating Individuals with Parkinson's Disease from Control SubjectsPhoni by S.karger Ag - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEObjective: To investigate whether syllables produced in an oral diadochokinetic (DDK) task may be quantified so that persons with Parkinson's disease (PD) perceived to have reduced articulatory precision when reading may be correctly identified using that quantification. Patients...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Impact of Dysarthria on Laypersons' Attitudes towards Adults with Cerebral Palsy Phoni by S.karger...
The Impact of Dysarthria on Laypersons' Attitudes towards Adults with Cerebral PalsyPhoni by S.karger Ag - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEObjective: This study investigated laypersons' attitudes towards adults with dysarthria due to cerebral palsy (CP). We aimed to explore the impact of the overall severity and of specific symptoms of dysarthria on laypersons' evaluations. Patients and Methods: Eighteen adults with dysarthria due to CP and 6 nondysarthric controls participated as speakers....
Αλέξανδρος Γ. Σφακιανάκης
1h
Automated Speech Recognition in Adult Stroke Survivors: Comparing Human and Computer Transcriptions...
Automated Speech Recognition in Adult Stroke Survivors: Comparing Human and Computer TranscriptionsPhoni by S.karger Ag - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEObjective: Speech sound errors are common in people with a variety of communication disorders and can result in impaired message transmission to listeners. Valid and reliable metrics exist to quantify this problem, but they are rarely used in clinical settings due to the time-intensive nature of speech transcription by humans. Automated...
Αλέξανδρος Γ. Σφακιανάκης
1h
Spectral/Cepstral Analyses of Phonation in Parkinson's Disease before and after Voice Treatment:...
Spectral/Cepstral Analyses of Phonation in Parkinson's Disease before and after Voice Treatment: A Preliminary StudyPhoni by S.karger Ag - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEPurpose: This article examines cepstral/spectral analyses of sustained /α/ vowels produced by speakers with hypokinetic dysarthria secondary to idiopathic Parkinson's disease (PD) before and after Lee Silverman Voice Treatment (LSVT®LOUD) and the relationship of these measures with overall voice intensity. Methodology:Nine...
Αλέξανδρος Γ. Σφακιανάκης
1h
Applicability of Resonance Tube Phonation in Water for Semi-Occluded Vocal Tract Voice Training and...
Applicability of Resonance Tube Phonation in Water for Semi-Occluded Vocal Tract Voice Training and TherapyPhoni by S.karger Ag - 1d ago Preview    AUTO POST  SAVE TO EVERNOTEBackground: Exercises involving tube phonation in water (TPW) have emerged as an alternative to conventional voice therapy techniques. The objective was to determine whether the results of these techniques were comparable to each other for the treatment of voice pathology, as well as to compare the costs implicated in the delivery...
Αλέξανδρος Γ. Σφακιανάκης
1h
Production of Vowels by Electrolaryngeal Speakers Using Clear Speech Phoni by S.karger Ag - 15h ago Preview...
Production of Vowels by Electrolaryngeal Speakers Using Clear SpeechPhoni by S.karger Ag - 15h ago Preview    AUTO POST  SAVE TO EVERNOTEBackground/Aims: This study examined the effect of clear speech on vowel productions by electrolaryngeal speakers. Method: Ten electrolaryngeal speakers produced eighteen words containing /i/, /ɪ/, /ɛ/, /æ/, /eɪ/, and /oʊ/ using habitual speech and clear speech. Twelve listeners transcribed 360 words, and a total of 4,320 vowel stimuli across speaking conditions,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Maximum Performance Tests in the Assessment of Neurogenic Speech Impairment Phoni by S.karger Ag...
Maximum Performance Tests in the Assessment of Neurogenic Speech ImpairmentPhoni by S.karger Ag - 13h ago Preview    AUTO POST  SAVE TO EVERNOTEBackground: Maximum performance tests are widely used in dysarthria assessment. From a theoretical perspective, the motor demands of such tasks differ from those of speaking. Therefore, their validity as measures of dysarthric impairment needs to be established empirically. Patients and Methods: Maximum phonation time (MPT) and maximum syllable repetition...
Αλέξανδρος Γ. Σφακιανάκης
1h
Exploring gender as a potential source of bias in adult judgments of children with Specific Language...
Exploring gender as a potential source of bias in adult judgments of children with Specific Language Impairment and Attention-Deficit/Hyperactivity DisorderJournal of Communication Disorders (open.. - 11h ago Preview    AUTO POST  SAVE TO EVERNOTEPublication date: Available online 23 May 2019Source: Journal of Communication DisordersAuthor(s): Alison Elizabeth Shimko, Sean Redmond, Amy Ludlow, Andrea AshAbstractThe purpose of this follow up study to Ludlow (2013) was to examine potential sources...
Αλέξανδρος Γ. Σφακιανάκης
1h
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale
Une tumeur sous-muqueuse de la base de languePublication date: April 2019Source: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 136, Issue 2Author(s): A. Ko, C.-L. Hyun, G.-C. LimVésicules endobuccales, pharyngées et laryngées unilatéralesPublication date: April 2019Source: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 136, Issue 2Author(s): L. Alciato, P. Bonfils, F. RubinLes pharyngotomies latéralesPublication date: April...
Αλέξανδρος Γ. Σφακιανάκης
1h
Oral Biology
BMP4 mutations in tooth agenesis and low bone massPublication date: July 2019Source: Archives of Oral Biology, Volume 103Author(s): Miao Yu, Hao Wang, Zhuangzhuang Fan, Chencheng Xie, Haochen Liu, Yang Liu, Dong Han, Sing-Wai Wong, Hailan FengAbstractObjectiveTo identify an uncommon genetic cause of tooth agenesis (TA) by utilizing whole exome sequencing (WES) and targeted Sanger sequencing in a cohort of 120 patients with isolated TA.DesignOne deleterious mutation in the gene encoding bone morphogenetic...
Αλέξανδρος Γ. Σφακιανάκης
2h
NeuroImage
Shared neural representations of syntax during online dyadic communicationPublication date: September 2019Source: NeuroImage, Volume 198Author(s): Wenda Liu, Holly P. Branigan, Lifen Zheng, Yuhang Long, Xialu Bai, Kanyu Li, Hui Zhao, Siyuan Zhou, Martin J. Pickering, Chunming LuAbstractWhen people communicate, they come to see the world in a similar way to each other by aligning their mental representations at such levels as syntax. Syntax is an essential feature of human language that distinguishes...
Αλέξανδρος Γ. Σφακιανάκης
2h
Cardiothoracic Anesthesia
Pressure-regulated volume control mode versus synchronized intermittent mandatory ventilation mode in management of acute respiratory failure complicating advanced liver diseaseRafik Yousset Atalla, Dalia Fahmy Emam, Wail Ahmed AbdelaalThe Egyptian Journal of Cardiothoracic Anesthesia 2018 12(3):35-41Background A common cause of death in the ICUs is advanced liver disease and its complications. Respiratory complications are common in patients with advanced liver disease. Management of patients with...
Αλέξανδρος Γ. Σφακιανάκης
2h
Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480

Medical Specialities

Burden of antenatal depression and its risk factors in Indian settings: A systematic review
Priyanka Arora, Bani Tamber Aeri

Indian Journal of Medical Specialities 2019 10(2):55-60

According to the National Mental Health Survey-2016, one in every ten persons in India suffers from depression and anxiety, and 20% of these depressed Indians are pregnant women and new mothers. This systematic review was conducted to assess the burden of depression and risk factors associated with it among the Indian pregnant women. Electronic database (PubMed and Google Scholar) was used to identify any retrospective/prospective observational research studies published in English language which specifically examined antenatal depression (AD) among Indian women using a validated scale. A total of 995 citations were retrieved, out of which only eight studies were included. The prevalence of AD was found to be ranging from 9.18% to 65.0% in northern, western, and southern part of India. However, there is a lack of research on AD from the eastern part of country. The factors such as unplanned pregnancy, multigravidity, history of abortion, advancing pregnancy and age, lower/lower-middle socioeconomic status, poor education status of women, unemployment, bad relations with in-laws, male gender preference, and demand for dowry were significant predictors for AD. Therefore, it is necessary to provide the health-care professionals and women with the knowledge about these factors for early prediction of women at high risk of AD, which might help them to get timely intervention and reduce the burden of depression. Furthermore, the results from this review implicate that more research is needed in future in this field to further validate the findings of the present review. 


Therapeutic benefits of lenalidomide in hematological malignancies
Mohammed Shafi Abdulsalam, Durai Mavalavan Vasudevan Manimoliyan

Indian Journal of Medical Specialities 2019 10(2):61-65

Lenalidomide is an immunomodulatory agent, which has action against most of the hematological malignancies. Apart from its immunomodulation, it has other properties such as antiproliferation and antiangiogenesis. It is not only effective in myelodysplastic syndromes and myeloma, recent studies show its effective action on newly diagnosed and relapsed/refractory lymphomas as well. Addition of lenalidomide to standard therapy is associated with lesser central nervous system relapse in diffuse large B-cell lymphomas. Lenalidomide shows promising results in Hodgkin's lymphomas and leukemias (acute myeloid leukemia and chronic lymphocytic leukemia). Dose escalation may be an option in nonresponders with caution in side effects. 


Sources and toxicological effects of lead on human health
Bikash Debnath, Waikhom Somraj Singh, Kuntal Manna

Indian Journal of Medical Specialities 2019 10(2):66-71

Lead toxicity is one of the most hazardous metal toxicities. It can enter the body through lead-based paint, dust, water, soil, tableware, and folk medicines. Children are especially prone to develop lead toxicity. Lead acts by inducing oxidative stress due to inefficient replenishment of glutathione. Lead can also cause hemolytic anemia due to disruption of the cellular membrane by lipid peroxidation. Lead toxicity also affects neurotransmitter levels and causes severe health issues related to organ damage, some even leading to death. The main aim of this review article is to summarize lead toxicity detection, its sources, and its mechanism including various toxicological effects on human health. It also focuses on the prevention and treatment of lead toxicity. 


Correlation between nephropathy and ophthalmic complications in cases of sickle cell anemia: An entangled association
Aditi Pareek, Aditya Khandekar, Sourya Acharya, Pravin Tidake, Samarth Shukla

Indian Journal of Medical Specialities 2019 10(2):72-75

Background: Sickle cell disease commonly presents with unpredictable episodes of vasocclusion and pre mature RBC destruction, which manifest as acute pain and tissue ischemia. In kidneys, endothelial dysfunction occurs in the nephron leading to microalbuminuria, vaso-occlusion, ischemia, infarction, and ultimately nephron loss. Proliferative and non-proliferative retinal changes can also occur, due to similar underlying pathophysiology of vasospasm. Aims and Objectives: To study the correlation between Sickle Cell Nephropathy and Ophthalmic Complications in cases of Sickle Cell disease. Materials and Methods: Thirty five adults aged 18 to 60 years, having Sickle Cell disease were selected as study participants. Complete blood analysis was carried out, with assessment of Urine Albumin: Creatinine ratio and ophthalmic findings, studied by direct and indirect ophthalmoscopy, and slit-lamp biomicroscopy. Results: Patients were divided into two categories: Category I comprising of 7 patients who were admitted to the Medicine ICU with Crisis, and Category II comprising of 28 clinically stable patients. 5 patients from Category I (71.4%), and 2 patients from Category II (7.1%), were found to have findings of peripheral retinopathy. Category I patients had received a mean of 6.17 ± 2.14 blood transfusions, Category II patients had received 2.89 ± 1.81 transfusions, difference being statistically significant. Mean Hb in Category I patients was 6.37 ± 0.35 gm/dl, compared to 7.95 ± 0.81 gm/dl in Category II patients. The mean Urine Albumin/ Creatinine ratio of patients having Ophthalmic manifestations was found to be 286.71 ± 74.75 mg/g, while the mean Urine Albumin/ Creatinine ratio of patients with no Ophthalmic manifestations was found to be 31.82 ± 4.48 mg/g, difference being statistically significant. Conclusion: Sickle Cell nephropathy and retinopathy appear to stem as manifestations of a common underlying mechanism of sickle vasculopathy, and thus can be studied as markers for each other. 


The knowledge, attitude, and practices relating to tuberculosis among drug-resistant tuberculosis patients
Kevisetuo Anthony Dzeyie, Saurav Basu, Tanzin Dikid

Indian Journal of Medical Specialities 2019 10(2):76-78

Introduction: A tuberculosis patient infects several healthy people prior to the diagnosis and initiation of treatment. Indiscriminate spitting in the community has been identified as a challenge to the prevention of tuberculosis; however, knowledge is still limited in terms of actual practices. Methodology: We conducted a descriptive cross-sectional study at a tertiary care hospital to evaluate knowledge, attitude, and practices relating to tuberculosis by interviewing patients of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis using a semi-structured questionnaire. We evaluated knowledge of tuberculosis on etiology, mode of spread, treatment factors, attitudes on the importance the respondent attributed to the factor and practices on adherence to treatment, and hygiene for the prevention of spread including safe sputum disposal. Results: We enrolled 250 patients (165 males) with a mean age of 29 ± 11 (mean ± standard deviation) years. On knowledge of tuberculosis, most of the patients had correct knowledge regarding tuberculosis symptoms (241, 96%), mode of spread (235, 94%), and correct duration of treatments 246 (98%) for drug sensitive tuberculosis. On attitude, all the patients consider adherence to their prescribed anti-tubercular treatment, 246 (98%) on covering mouth while coughing or sneezing and 239 (96%) on safe disposal of sputum as important. However, only 45 (18%) reported practicing correct sputum disposal and 66 (26%) patients reported disposing of their sputum in the open. Conclusion: This study suggests that despite good knowledge and attitude, there is a lack in practice of safe disposal of sputum by tuberculosis patients. Efforts toward sensitization regarding safe disposal of sputum need to be strengthened. 


Association of demographic and lifestyle factors with semen quality of men with fertility problems attending infertility center in North Karnataka
Makhadumsab M Toragall, Sanat K Satapathy, Girish G Kadadevaru, Murigendra B Hiremath

Indian Journal of Medical Specialities 2019 10(2):79-83

Background: Male factor is responsible for 50% of infertility cases. Universal deterioration in human sperm quality occurring in recent times is receiving a greater attention. The impact of numerous lifestyle factors including age, smoking, alcohol consumption, and exposure to occupational and environmental pollutants is unfavorable to male reproductive health. The present study intended to find out the association of demographic, occupational, and several lifestyle factors on semen quality of men diagnosed with infertility. Materials and Methods: The study enlisted 432 men diagnosed with fertility issue. Couples were administrated with a structured questionnaire to provide their demographic attributes and medical and reproductive health information. The collected data were statistically analyzed using SPSS software version 20.0. Results: The mean age of men was 34.44 ± 0.21 years at the time of consultation. Among seven semen abnormalities, asthenozoospermia was recorded the highest (30.09%). Most of the participants were having secondary education (32.26%), working as laborers (26.62%), and were having multiple addictions (27.77%). Decreased sperm count and motility was noticed among advanced age group and those with addictions. Different occupational statuses had substantial correlation with the sperm quality of participants. Conclusion: The incidence of male infertility and the potent lifestyle aspects studied have displayed an association with each other. However, influence of these aspects on impairment of male fertility can be overcome with modification toward healthier lifestyle. 


The cognitive profile and executive function of progressive supranuclear palsy and multiple system atrophy patients
Divya Goel, Arvind Vyas

Indian Journal of Medical Specialities 2019 10(2):84-88

Introduction: Multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) are two relatively common forms of atypical parkinsonism seen in movement disorder clinics. This study provides an insight into the cognitive dysfunction in these two diseases. Aims: This study aims at assessing the cognitive and executive dysfunction and investigating the relationship between age, education, Montreal cognitive assessment (MOCA), and frontal assessment battery (FAB) score in a group of Indian patients with MSA and PSP. Materials and Methods: This is a hospital-based observational study with the recruitment of patients of MSA and PSP based on consensus criteria and The National Institute of Neurological Disorders and Stroke and Society for Progressive Supranuclear Palsy criteria, respectively. A total of 50 patients of MSA and PSP admitted or attending outpatient department in the Department of Neurology, SMS hospital, Jaipur, were analyzed for cognitive and executive functions between December 2016 and December 2018 using MOCA and FAB. The Student's t-test was used. The level of significance was determined as itsP value withP < 0.05 taken as statistically significant. Results: On MOCA, impairment was observed in 24% of cases of MSA and 92% of cases of PSP. On FAB, impairment was observed in 20% of cases of MSA and 72% of cases of PSP. Conclusions: Cognitive dysfunction is a major finding in PSP and MSA patients. Thus, cognitive dysfunction in a patient does not rule out MSA as considered in the previous literature and is an important diagnostic finding in PSP; yet requires future research on a larger scale. 


Prevalence of intestinal parasites and risk factors with emphasis on Enterobius vermicularis in children of daycares and preparatory schools of the city of Khodabandeh, Northwestern Iran
Khadejeh Salahi, Amir Javadi, Mehrzad Saraei

Indian Journal of Medical Specialities 2019 10(2):89-94

Introduction: Intestinal parasitic infections (IPIs) are considered as a common cause of morbidity and mortality in children in the developing countries. The present study was aimed at examining the status of IPIs in the children of daycares and preparatory schools in the city of Khodabandeh located at Northwestern Iran. Materials and Methods: A total of 520 daycare and preprimary school-age children in the northwest of Iran were tested for the presence of intestinal parasites using direct smear and the standard formalin-ethyl acetate sedimentation techniques. Furthermore, the specific “scotch tape” test was used to identify the eggs of pinworm Enterobius vermicularis. Results: Of total 520 children, 55 cases (10.6%) were infected to intestinal parasites, including 9.2% monoparasitism and 1.4% double-parasitism. The prevalence rate for protozoan infections was 7.3% and 3.65% for helminths. Giardia lamblia infection was shown to have the highest prevalence rate among intestinal protozoa by 3.26%. The prevalence rate for E. vermicularis was 3.5% using “scotch tape” test and stool examination. There was a significant correlation between infection with intestinal parasites and daycares (P = 0.004). A significant inverse correlation was established between anal itching (as a sign of E. vermicularis infections) and hand-washing in children using soap or hand-washing liquid (P = 0.004). Conclusions: Infection with intestinal parasites in children of nursery schools and preschools of the study region, compared to the previous situation, is considerably decreased. 


Insulin resistance as a predictor of sensory neuropathy in prediabetes
Amrinder Singh, Ajay Chauhan, Parul Goyal, Jasmeet Kaur, Priyamvadha Ramesh

Indian Journal of Medical Specialities 2019 10(2):95-98

Objective: The aim of this study is to assess the association of insulin resistance with sensory neuropathy in prediabetes. Materials and Methods: Fasting serum insulin levels were measured and the homeostatic model assessment of insulin resistance (HOMA-IR) was calculated in all patients. These were compared in prediabetic patients having sensory neuropathy to those who did not have sensory neuropathy as determined by vibration perception thresholds (VPTs) measured using Digital Biothesiometer. Furthermore, direct correlation between insulin resistance and VPTs was checked. Results: A total of 60 prediabetic cases were included in this study. Among the study population, the age distribution ranged from 35 years to 60 years with the mean age of 48.68 years. Male and female formed 65% and 35% of the study population, respectively. The maximum fasting serum insulin levels were 21.8 mIU/L, and the minimum fasting serum insulin levels were 3.5 mIU/L, with the mean value being 10.61 ± 4.99 mIU/L. The maximum HOMA-IR was 6.4, and the minimum was 0.986, with the mean value being 2.81 ± 1.37. Among all the prediabetic patients, 43.3% of patients had neuropathy according to VPTs measured using Biothesiometer. T-test analysis suggests that mean fasting serum insulin levels (P = 0.026) and HOMA-IR (P = 0.032) were significantly higher in patients with neuropathy than patients without neuropathy. VPTs were found to have statistically significant positive correlation with fasting serum insulin levels (Pearson correlation coefficient = 0.317 [R], 0.296 [L];P = 0.013 [R], 0.022 [L]) and HOMA-IR (Pearson correlation coefficient = 0.299 [R], 0.281 [L];P = 0.02 [R], 0.03 [L]). Conclusion: Insulin resistance, quantified with the help of the index, HOMA-IR, has an important role in the development of this sensory neuropathy. 


Correlation between serum lipid fractions and radiological severity in patients with drug-resistant pulmonary tuberculosis: A cross-sectional pilot study
Alam Nawaz, Manel Arjun Nayak, Subhangi Thakur Hameer, Ashwin Kamath, Ajit Mahale

Indian Journal of Medical Specialities 2019 10(2):99-104

Background: We aimed to determine if serum cholesterol and body mass index (BMI), which are important in maintaining immunity, have any impact on the radiological severity in patients with drug-resistant pulmonary tuberculosis (DR-TB). Materials and Methods: A cross-sectional pilot study was conducted over 2 years in adults with newly diagnosed DR-TB. The radiological severity of the disease was determined using a chest X-ray (CXR) scoring formula. Correlation between the lipid fraction levels, BMI, and the CXR scores was determined using Pearson's correlation coefficient. Results: Thirty-three patients were included in the study. A significant negative correlation was seen between the CXR severity scores and total cholesterol (r = −0.546,P = 0.001), high-density lipoprotein-cholesterol (r = −0.479,P = 0.005), low-density lipoprotein-cholesterol (r = −0.431,P = 0.012), and BMI (r = −0.352,P = 0.044). Conclusions: Low serum cholesterol levels and low BMI were associated with an increased radiological severity which, in turn, could result in increased infectivity. Adequate nutritional supplementation in the diet of patients to increase BMI, and serum cholesterol levels, could potentially decrease the severity, and also consequently, transmission, and incidence of DR-TB. 


Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480