Τρίτη 24 Οκτωβρίου 2017

Tongue- and Jaw-Specific Contributions to Acoustic Vowel Contrast Changes in the Diphthong /ai/ in Response to Slow, Loud, and Clear Speech

Purpose
This study sought to determine decoupled tongue and jaw displacement changes and their specific contributions to acoustic vowel contrast changes during slow, loud, and clear speech.
Method
Twenty typical talkers repeated “see a kite again” 5 times in 4 speech conditions (typical, slow, loud, clear). Speech kinematics were recorded using 3-dimensional electromagnetic articulography. Tongue composite displacement, decoupled tongue displacement, and jaw displacement during /ai/, as well as the distance between /a/ and /i/ in the F1–F2 vowel space, were examined during the diphthong /ai/ in “kite.”
Results
Displacements significantly increased during all 3 speech modifications. However, jaw displacements increased significantly more during clear speech than during loud and slow speech, whereas decoupled tongue displacements increased significantly more during slow speech than during clear and loud speech. In addition, decoupled tongue displacements increased significantly more during clear speech than during loud speech. Increases in acoustic vowel contrast tended to be larger during slow speech than during clear speech and were predominantly tongue-driven, whereas those during clear speech were fairly equally accounted for by changes in decoupled tongue and jaw displacements. Increases in acoustic vowel contrast during loud speech were smallest and were predominantly tongue-driven, particularly in men.
Conclusions
Findings suggest that task-specific patterns of decoupled tongue and jaw displacement change and task-specific patterns of decoupled tongue and jaw contributions to vowel acoustic change across these speech modifications. Clinical implications are discussed.

from #Audiology via ola Kala on Inoreader http://article/doi/10.1044/2017_JSLHR-S-17-0114/2660093/Tongue-and-JawSpecific-Contributions-to-Acoustic
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Tongue- and Jaw-Specific Contributions to Acoustic Vowel Contrast Changes in the Diphthong /ai/ in Response to Slow, Loud, and Clear Speech

Purpose
This study sought to determine decoupled tongue and jaw displacement changes and their specific contributions to acoustic vowel contrast changes during slow, loud, and clear speech.
Method
Twenty typical talkers repeated “see a kite again” 5 times in 4 speech conditions (typical, slow, loud, clear). Speech kinematics were recorded using 3-dimensional electromagnetic articulography. Tongue composite displacement, decoupled tongue displacement, and jaw displacement during /ai/, as well as the distance between /a/ and /i/ in the F1–F2 vowel space, were examined during the diphthong /ai/ in “kite.”
Results
Displacements significantly increased during all 3 speech modifications. However, jaw displacements increased significantly more during clear speech than during loud and slow speech, whereas decoupled tongue displacements increased significantly more during slow speech than during clear and loud speech. In addition, decoupled tongue displacements increased significantly more during clear speech than during loud speech. Increases in acoustic vowel contrast tended to be larger during slow speech than during clear speech and were predominantly tongue-driven, whereas those during clear speech were fairly equally accounted for by changes in decoupled tongue and jaw displacements. Increases in acoustic vowel contrast during loud speech were smallest and were predominantly tongue-driven, particularly in men.
Conclusions
Findings suggest that task-specific patterns of decoupled tongue and jaw displacement change and task-specific patterns of decoupled tongue and jaw contributions to vowel acoustic change across these speech modifications. Clinical implications are discussed.

from #Audiology via xlomafota13 on Inoreader http://article/doi/10.1044/2017_JSLHR-S-17-0114/2660093/Tongue-and-JawSpecific-Contributions-to-Acoustic
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Is the Voice of Professional Voice Users With no Vocal Cord Lesions Similar to That of Non Professional Voice Users?

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Publication date: Available online 24 October 2017
Source:Journal of Voice
Author(s): Chandala Chitguppi, Anoop Raj, Ravi Meher, P.K. Rathore
ObjectiveThe objective of this study was to analyze if the voice of professional voice users (PVU) is comparable with that of a nonprofessional voice users (NPVUs), both of whom have no obvious vocal cord lesions.Materials and MethodsFifty professional and 50 NPVUs with no obvious vocal fold pathologies underwent voice analysis and videostroboscopic study, and various parameters were analyzed.ResultsMajority of the participants were found to be less than 40 years. Teachers formed the largest group (40%) of PVUs. PVUs had a significantly higher incidence of voice-related complaints compared with NPVUs. The former group also showed a higher deviation from the normative data. A significant influence of gender and the duration of work experience was also observed among PVUs.ConclusionsThe voice of an apparently normal PVU is not similar to that of an apparently normal NPVU. Female PVUs and PVUs with a longer duration of work experience show the highest deviation from normative data.



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Laryngocardiac Reflex: A Case Report and Review of the Literature

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Publication date: Available online 24 October 2017
Source:Journal of Voice
Author(s): Christian S. Pingree, Jacob S. Majors, Nelson S. Howard, Robert L. Eller
IntroductionThe vagus nerve has sensory and motor function in the larynx, as well as parasympathetic function in the thorax and abdomen. Stimulation of the superior laryngeal nerve can cause reflexive bradycardia.CaseWe describe a case of a 45-year-old man with pre-syncopal symptoms while exercising, and bradycardia found during cardiology workup. Radiography and flexible laryngoscopy showed evidence of a right-sided, vascular laryngeal mass. Exercise testing before and after superior laryngeal nerve block showed reversal of the symptoms with the block. Subsequent resection of the lymphovascular malformation with CO2 laser eliminated the patient's symptoms.DiscussionThis is the first case reported of the laryngocardiac reflex producing symptomatic bradycardia as a result of exercise-induced engorgement of a supraglottic lymphovascular malformation, which was then cured by surgical excision. We discuss this case and the literature regarding lymphovascular malformations in the airway and the neural pathways of the laryngocardiac reflex.



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The risk ratio for development of hereditary sensorineural hearing loss in consanguineous marriage offspring.

http:--linkinghub.elsevier.com-ihub-imag Related Articles

The risk ratio for development of hereditary sensorineural hearing loss in consanguineous marriage offspring.

Int J Pediatr Otorhinolaryngol. 2017 Oct;101:7-10

Authors: Sanyelbhaa H, Kabel A, Abo El-Naga HAE, Sanyelbhaa A, Salem H

Abstract
OBJECTIVES: This study aims to define the relative risk of development of hearing loss in offspring of consanguineous marriages.
MATERIALS AND METHODS: This is a retrospective case-control study conducted in a tertiary referral center in Jeddah, KSA. The study group included 1600 probands (848 males, 752 females), with age range 0.5-12 years (6.6 ± 3.6). The study group comprised of two equal, age and sex matched subgroups; Hearing Loss (HL) group and Normal Hearing (NH) group. The children included in the HL group should have idiopathic or non syndromic genetic sensorineural hearing loss.
RESULTS: The HL Group comprised 800 children with variable degrees of sensorineural hearing loss. Profound and severe degrees of hearing loss were the most prevalent degrees (P <0.05%). The prevalence of consanguineous marriage offspring in the NH group was 42.5%, while in the HL group it was 68.9% (P < 0.05). The differences between both study subgroups regarding the distribution of different degrees of parental consanguinity (first, second, double first, and first once removed cousins) were insignificant (P > 0.05). The relative risk and 95% confidence interval (RR, 95% CI) for development of hearing loss in offspring of consanguineous marriage was 1.76 (95% CI 1.57-1.97, P < 0.001).
CONCLUSIONS: There was 76% increased risk for consanguineous marriage progeny to develop SNHL when compared to non consanguineous progeny.

PMID: 28964313 [PubMed - indexed for MEDLINE]



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Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes.

Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes.

Methods Mol Biol. 2018;1684:129-150

Authors: Del Mármol J, Rietmeijer RA, Brohawn SG

Abstract
Mechanical force sensation is fundamental to a wide breadth of biology from the classic senses of touch, pain, hearing, and balance to less conspicuous sensations of proprioception, blood pressure, and osmolarity and basic aspects of cell growth, differentiation, and development. These diverse and essential systems use force-gated (or mechanosensitive) ion channels that convert mechanical stimuli into cellular electrical signals. TRAAK, TREK1, and TREK2 are K(+)-selective ion channels of the two-pore domain K(+) (K2P) family that are mechanosensitive: they are gated open by increasing membrane tension. TRAAK and TREK channels are thought to play roles in somatosensory and other mechanosensory processes in neuronal and non-neuronal tissues. Here, we present protocols for three assays to study mechanical activation of these channels in cell membranes: (1) cell swelling, (2) cell poking, and (3) patched membrane stretching. Patched membrane stretching is also applicable to the study of mechanosensitive K2P channel activity in a cell-free system and a procedure for proteoliposome reconstitution and patching is also presented. These approaches are also readily applicable to the study of other mechanosensitive ion channels.

PMID: 29058189 [PubMed - in process]



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Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes.

Studying Mechanosensitivity of Two-Pore Domain K(+) Channels in Cellular and Reconstituted Proteoliposome Membranes.

Methods Mol Biol. 2018;1684:129-150

Authors: Del Mármol J, Rietmeijer RA, Brohawn SG

Abstract
Mechanical force sensation is fundamental to a wide breadth of biology from the classic senses of touch, pain, hearing, and balance to less conspicuous sensations of proprioception, blood pressure, and osmolarity and basic aspects of cell growth, differentiation, and development. These diverse and essential systems use force-gated (or mechanosensitive) ion channels that convert mechanical stimuli into cellular electrical signals. TRAAK, TREK1, and TREK2 are K(+)-selective ion channels of the two-pore domain K(+) (K2P) family that are mechanosensitive: they are gated open by increasing membrane tension. TRAAK and TREK channels are thought to play roles in somatosensory and other mechanosensory processes in neuronal and non-neuronal tissues. Here, we present protocols for three assays to study mechanical activation of these channels in cell membranes: (1) cell swelling, (2) cell poking, and (3) patched membrane stretching. Patched membrane stretching is also applicable to the study of mechanosensitive K2P channel activity in a cell-free system and a procedure for proteoliposome reconstitution and patching is also presented. These approaches are also readily applicable to the study of other mechanosensitive ion channels.

PMID: 29058189 [PubMed - in process]



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