A Is lower peripheral information weighted differently as a function of step number during step climbing?

Publication date: Available online 13 November 2016
Source:Gait & Posture
Author(s): Valentina Graci, Marco Rabuffetti, Carlo Frigo, Maurizio Ferrarin
The importance of peripheral visual information during stair climbing and how peripheral visual information is weighted as a function of step number during step climbing is unclear. Previous authors postulated that the knowledge of predictable characteristics of the steps may decrease reliance on foveal vision and transfer the online visual guidance of stair climbing to peripheral vision. Hence the aim of this study was to investigate if and how the occlusion of the lower peripheral visual field influenced stair climbing and if peripheral visual information was weighted differently between steps.Ten young adult male participants ascended a 5-step staircase under 2 visual conditions: full vision (FV) and lower visual occlusion (LO). Kinematic data (100Hz) were collected. The effect of Vision and Step condition on vertical forefoot clearance was examined with a Repeated Measures 2-way ANOVA. Tukey’s HSD test was used for post-hoc comparisons. A significant main effect of Step and interaction Vision x Step were found (p=0.04): vertical forefoot clearance was greater on the last step compared to the other steps (p<0.01) and in LO compared to FV condition only on the 1st and the 2nd steps (p<0.013).These findings suggest that online peripheral visual information is more relevant when negotiating the first two steps, rather than the end of a staircase and that the steps subsequent the first few ones may require different information likely based on proprioception or working memory of the step height.



from #Audiology via xlomafota13 on Inoreader http://ift.tt/2eT5fNp
via IFTTT

A Is lower peripheral information weighted differently as a function of step number during step climbing?

Publication date: Available online 13 November 2016
Source:Gait & Posture
Author(s): Valentina Graci, Marco Rabuffetti, Carlo Frigo, Maurizio Ferrarin
The importance of peripheral visual information during stair climbing and how peripheral visual information is weighted as a function of step number during step climbing is unclear. Previous authors postulated that the knowledge of predictable characteristics of the steps may decrease reliance on foveal vision and transfer the online visual guidance of stair climbing to peripheral vision. Hence the aim of this study was to investigate if and how the occlusion of the lower peripheral visual field influenced stair climbing and if peripheral visual information was weighted differently between steps.Ten young adult male participants ascended a 5-step staircase under 2 visual conditions: full vision (FV) and lower visual occlusion (LO). Kinematic data (100Hz) were collected. The effect of Vision and Step condition on vertical forefoot clearance was examined with a Repeated Measures 2-way ANOVA. Tukey’s HSD test was used for post-hoc comparisons. A significant main effect of Step and interaction Vision x Step were found (p=0.04): vertical forefoot clearance was greater on the last step compared to the other steps (p<0.01) and in LO compared to FV condition only on the 1st and the 2nd steps (p<0.013).These findings suggest that online peripheral visual information is more relevant when negotiating the first two steps, rather than the end of a staircase and that the steps subsequent the first few ones may require different information likely based on proprioception or working memory of the step height.



from #Audiology via ola Kala on Inoreader http://ift.tt/2eT5fNp
via IFTTT

A Is lower peripheral information weighted differently as a function of step number during step climbing?

Publication date: Available online 13 November 2016
Source:Gait & Posture
Author(s): Valentina Graci, Marco Rabuffetti, Carlo Frigo, Maurizio Ferrarin
The importance of peripheral visual information during stair climbing and how peripheral visual information is weighted as a function of step number during step climbing is unclear. Previous authors postulated that the knowledge of predictable characteristics of the steps may decrease reliance on foveal vision and transfer the online visual guidance of stair climbing to peripheral vision. Hence the aim of this study was to investigate if and how the occlusion of the lower peripheral visual field influenced stair climbing and if peripheral visual information was weighted differently between steps.Ten young adult male participants ascended a 5-step staircase under 2 visual conditions: full vision (FV) and lower visual occlusion (LO). Kinematic data (100Hz) were collected. The effect of Vision and Step condition on vertical forefoot clearance was examined with a Repeated Measures 2-way ANOVA. Tukey’s HSD test was used for post-hoc comparisons. A significant main effect of Step and interaction Vision x Step were found (p=0.04): vertical forefoot clearance was greater on the last step compared to the other steps (p<0.01) and in LO compared to FV condition only on the 1st and the 2nd steps (p<0.013).These findings suggest that online peripheral visual information is more relevant when negotiating the first two steps, rather than the end of a staircase and that the steps subsequent the first few ones may require different information likely based on proprioception or working memory of the step height.



from #Audiology via ola Kala on Inoreader http://ift.tt/2eT5fNp
via IFTTT

A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect.

A common variant in CLDN14 causes precipitous, prelingual sensorineural hearing loss in multiple families due to founder effect.

Hum Genet. 2016 Nov 12;

Authors: Pater JA, Benteau T, Griffin A, Penney C, Stanton SG, Predham S, Kielley B, Squires J, Zhou J, Li Q, Abdelfatah N, O'Rielly DD, Young TL

Abstract
Genetic isolates provide unprecedented opportunities to identify pathogenic mutations and explore the full natural history of clinically heterogeneous phenotypes such as hearing loss. We noticed a unique audioprofile, characterized by prelingual and rapid deterioration of hearing thresholds at frequencies >0.5 kHz in several adults from unrelated families from the island population of Newfoundland. Targeted serial Sanger sequencing of probands for deafness alleles (n = 23) that we previously identified in this founder population was negative. Whole exome sequencing in four members of the largest family (R2010) identified a CLDN14 (DFNB29) variant [c.488C>T; p. (Ala163Val)], likely pathogenic, sensorineural hearing loss, autosomal recessive. Although not associated with deafness or disease, CLDN14 p.(Ala163Val) has been previously reported as a variant of uncertain significance (VUS). Targeted sequencing of 169 deafness probands identified one homozygote and one heterozygous carrier. Genealogical studies, cascade sequencing and haplotype analysis across four unrelated families showed all subjects with the unique audioprofile (n = 12) were also homozygous for p.(Ala163Val) and shared a 1.4 Mb DFNB29-associated haplotype on chromosome 21. Most significantly, sequencing 175 population controls revealed 1% of the population are heterozygous for CLDN14 p.(Ala163Val), consistent with a major founder effect in Newfoundland. The youngest CLDN14 [c.488C>T; p.(Ala163Val)] homozygote passed newborn screening and had normal hearing thresholds up to 3 years of age, which then deteriorated to a precipitous loss >1 kHz during the first decade. Our study suggests that genetic testing may be necessary to identify at-risk children in time to prevent speech, language and developmental delay.

PMID: 27838790 [PubMed - as supplied by publisher]

from #Audiology via xlomafota13 on Inoreader http://ift.tt/2eSD6pD
via IFTTT

20Q: Rehabilitative Audiology - Remaining Competitive in a Changing Hearing Healthcare Environment

1. I know you’ve talked about the importance of rehabilitative audiology for many years. Still have the same beliefs today? Nancy Tye-Murray: Even more so! This is a crucial topic. The ground is shifting rapidly and many audiologists are expressing concerns about how changing government rules and regulations, new technologies such as personal sound amplification products (PSAPs), automated hearing tests, and inexpensive hearing aids offered by discount stores will impinge on their professional territory and even their livelihood.

from #Audiology via ola Kala on Inoreader http://ift.tt/2ewlSDm
via IFTTT

20Q: Rehabilitative Audiology - Remaining Competitive in a Changing Hearing Healthcare Environment

1. I know you’ve talked about the importance of rehabilitative audiology for many years. Still have the same beliefs today? Nancy Tye-Murray: Even more so! This is a crucial topic. The ground is shifting rapidly and many audiologists are expressing concerns about how changing government rules and regulations, new technologies such as personal sound amplification products (PSAPs), automated hearing tests, and inexpensive hearing aids offered by discount stores will impinge on their professional territory and even their livelihood.

from #Audiology via xlomafota13 on Inoreader http://ift.tt/2ewlSDm
via IFTTT

20Q: Rehabilitative Audiology - Remaining Competitive in a Changing Hearing Healthcare Environment

1. I know you’ve talked about the importance of rehabilitative audiology for many years. Still have the same beliefs today? Nancy Tye-Murray: Even more so! This is a crucial topic. The ground is shifting rapidly and many audiologists are expressing concerns about how changing government rules and regulations, new technologies such as personal sound amplification products (PSAPs), automated hearing tests, and inexpensive hearing aids offered by discount stores will impinge on their professional territory and even their livelihood.

from #Audiology via ola Kala on Inoreader http://ift.tt/2ewlSDm
via IFTTT