Πέμπτη 31 Αυγούστου 2017

Tympanometric assessment of Eustachian tube function as a prognostic indicator in myringoplasty

Suresh Babu Undavalli, Narayan Hanumanth Rao Kulkarni, Sukrit Bose, Anuradha Ananthaneni

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):14-18

Aim To determine eustachian tube function in tubo-tympanic type of chronic ear disease and correlate it with pathological changes in middle ear. Objective To ascertain whether eustachian tube function had any demeanor upon the outcome of myringoplasty. Backgound The prevailing interest in the patho-physiology of the eustachian tube has been stimulated by the persistent incidence of middle ear effusion and chronic otitis media. The ongoing sophistication in current middle ear reconstructive surgery has added more dimensions to the study of eustachian tube and its effects in the course of reconstructive middle ear surgery. One of the prime elements accountable for failure of reconstructive middle ear surgery has been tubal dysfunction. Method In the present study eustachian tube function was evaluated in in 30 patients who were undergoing myringoplasty for tubo-tympanic type of chronic suppurative otitis media having central perforation by tuning fork tests, microscopic evaluation of the middle ear mucosa and Impedance audiometry. Results 70% of the myringoplasty cases had good surgical outcome and of the 24 cases that had good eustation tube function 87.5% had successful surgical outcome remaining cases had recurrence of otorrhea. Conclusion The results were validating good eustachain tube function as a criterion for electing cases under middle ear reconstructive surgery and Impedance audiometer assures a superlative means of appraising Eustachain tube function.

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The role of antibiotics in treating secretory otitis media in children aged 2–12 years in an accredited teaching hospital in southeast Asia

Sarmishtha De, Kamal Kachhawa, Arun Gambhir, Rajesh K Jain, Rasmirekha Behera, Sanjay K Diwan, Sanjay Kumar

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):6-9

Introduction Secretory otitis media (SOM) is the most common clinical condition that can cause conductive deafness, especially among school-going children. The outcomes of hearing loss in children include speech problems, behavioral problems, and poor academic performance. Management of SOM therefore remains crucial. We carried out a comparative study of antibiotics versus surgical therapy for the treatment of SOM. Patients and methods The present study included 50 patients. Detailed history taking with ENT examinations was performed and documented in a validated pro forma. Routine investigations such as complete blood count, urine examination, audiological investigation such as impedance audiometry, etc, were carried out. Observation and results About 70% of the patients presented with symptoms of ear block with mouth breathing. Increased incidence was found in the 2–6 years age group. The present showed that surgery can increase the rate of recovery, shorten the duration of therapy, and prevent the recurrence of SOM compared with treatment with antibiotics. Conclusion Both the treatments have complications associated with them. Large, well-controlled studies can help resolve the risk–benefit ratio by measuring SOM recurrence, functional outcome, quality of life, and long-term outcomes.

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Sound therapy for tinnitus patients

Mohamed I Shabana, Abeir O Dabbous, Ayman M.M. Abdelkarim

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):1-5

Sound therapy, or use of any sound for the purposes of tinnitus management, is widely accepted as a management tool for tinnitus. Sound therapy have varying goals. Reducing the attention drawn to tinnitus, reducing the loudness of tinnitus, substituting a less disruptive noise. Sound therapy can be achieved with many modalities: Environmental Enrichment, tinnitus maskers, hearing aids and combination instruments such as: Danalogic iFIT Tinnitus, ReSound Live TS, Oticon’s Tinnitus “SoundSupport”, Phonak’s Tinnitus Balance and Widex Zen Fractal Tones. There are other sound devices e.g.: Acoustic Co-ordinated Reset, Neuromodulation, Serenade, Neuromonics, Phase-Out, Phase-shift and tinnitus inhibitory pathway activation. The advantages of sound therapy are: being non-invasive, reduce patient frustration and anxiety, some patients experience residual inhibition and it can facilitate patient’s habituation to tinnitus.

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Hearing profile in children with allergic rhinitis

Adekunle Adeyemo, Josephine Eziyi, Yemisi Amusa, Sanyaolu Ameye

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):10-13

Objective We carried out this study to determine the profile of hearing of children with allergic rhinitis compared with normal controls. Patients and methods Children with allergic rhinitis between the ages of 4 and 16 years attending the Otorhinolaryngology Clinics as well as age-matched and sex-matched controls were recruited into this study. We obtained the participants’ bio data, symptoms and duration using a structured interviewer questionnaire. We then carried out a pure tone audiometry on the participants. The degree of hearing loss was determined on the basis of the WHO standard classification. Results We recruited 99 children with clinical evidence of allergic rhinitis and an equal number of healthy controls completed the study. The mean age was 9.19±3.98 years in the test participants and 9.35±4.05 years in the controls, respectively. Mild hearing loss on the right side was more than twice as common among patients, 24 (24.2%), compared with the controls, 11(11.1%). Left-sided mild hearing loss was more than four times more prevalent among patients with allergic rhinitis, 26 (26.3%), compared with the controls, six (6.1%). Hearing threshold worse than 25 dB hearing level in the better-hearing ear was found to be significantly more prevalent among patients compared with the controls. Conclusion We could conclude that hearing is significantly worse in allergic children compared with controls, with disabling hearing loss being more significantly associated with allergic rhinitis.

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Comparison of two hearing aid fitting formulae in improving the patients’ satisfaction with amplification for experienced hearing aid users

Mohamed Shabana, Mona H Selim, Salwa M Abd El-Latif, Mona M Hamdy, Mai M El-Gohary

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):19-25

Introduction The effectiveness of real word satisfaction is very important for optimal hearing aid (HA) fitting, which can be assessed using self-report questionnaires. The Client Oriented Scale of Improvement (COSI) and Abbreviated Profile of Hearing Aid Benefit (APHAB) are useful tools for assessing the effectiveness of HA in achieving patient satisfaction. Patients and methods This study included 20 hearing-impaired adults. Their hearing thresholds ranged from moderate to moderately severe sensorineural hearing loss and had previous experience with HAs. Their ages ranged from 18 to 60 years, and the mean duration of HA experience was 3.85±5.02 years. Participants were examined in three scheduled sessions: unaided, aided National Acoustics Laboratories-Nonlinear 2 (NAL-NL2), and aided desired sensation level (DSL) v5. Each session was scheduled 2 months after the previous session. Patient satisfaction was assessed using the COSI and APHAB questionnaires for each HA fitting formulae. Results Both formulae have improved patient’s five client needs of the COSI; however, NAL-NL2 had better final ability score compared with DSL v5. Using the APHAB questionnaire, both formulae have decreased the listening difficulty score significantly. Using APHAB questionnaire, NAL-NL2 showed significantly less listening difficulty compared with DSL v5 as regards difficulties in ease of communication, broadband noise, and reverberation. However, both formulae did not improve ‘aversiveness’ conditions. Conclusion Questionnaires are equally important to audiometric tests and should not be underestimated and hence should be relied upon it in HA-fitting verification.

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Tympanometric assessment of Eustachian tube function as a prognostic indicator in myringoplasty

Suresh Babu Undavalli, Narayan Hanumanth Rao Kulkarni, Sukrit Bose, Anuradha Ananthaneni

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):14-18

Aim To determine eustachian tube function in tubo-tympanic type of chronic ear disease and correlate it with pathological changes in middle ear. Objective To ascertain whether eustachian tube function had any demeanor upon the outcome of myringoplasty. Backgound The prevailing interest in the patho-physiology of the eustachian tube has been stimulated by the persistent incidence of middle ear effusion and chronic otitis media. The ongoing sophistication in current middle ear reconstructive surgery has added more dimensions to the study of eustachian tube and its effects in the course of reconstructive middle ear surgery. One of the prime elements accountable for failure of reconstructive middle ear surgery has been tubal dysfunction. Method In the present study eustachian tube function was evaluated in in 30 patients who were undergoing myringoplasty for tubo-tympanic type of chronic suppurative otitis media having central perforation by tuning fork tests, microscopic evaluation of the middle ear mucosa and Impedance audiometry. Results 70% of the myringoplasty cases had good surgical outcome and of the 24 cases that had good eustation tube function 87.5% had successful surgical outcome remaining cases had recurrence of otorrhea. Conclusion The results were validating good eustachain tube function as a criterion for electing cases under middle ear reconstructive surgery and Impedance audiometer assures a superlative means of appraising Eustachain tube function.

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The role of antibiotics in treating secretory otitis media in children aged 2–12 years in an accredited teaching hospital in southeast Asia

Sarmishtha De, Kamal Kachhawa, Arun Gambhir, Rajesh K Jain, Rasmirekha Behera, Sanjay K Diwan, Sanjay Kumar

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):6-9

Introduction Secretory otitis media (SOM) is the most common clinical condition that can cause conductive deafness, especially among school-going children. The outcomes of hearing loss in children include speech problems, behavioral problems, and poor academic performance. Management of SOM therefore remains crucial. We carried out a comparative study of antibiotics versus surgical therapy for the treatment of SOM. Patients and methods The present study included 50 patients. Detailed history taking with ENT examinations was performed and documented in a validated pro forma. Routine investigations such as complete blood count, urine examination, audiological investigation such as impedance audiometry, etc, were carried out. Observation and results About 70% of the patients presented with symptoms of ear block with mouth breathing. Increased incidence was found in the 2–6 years age group. The present showed that surgery can increase the rate of recovery, shorten the duration of therapy, and prevent the recurrence of SOM compared with treatment with antibiotics. Conclusion Both the treatments have complications associated with them. Large, well-controlled studies can help resolve the risk–benefit ratio by measuring SOM recurrence, functional outcome, quality of life, and long-term outcomes.

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Sound therapy for tinnitus patients

Mohamed I Shabana, Abeir O Dabbous, Ayman M.M. Abdelkarim

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):1-5

Sound therapy, or use of any sound for the purposes of tinnitus management, is widely accepted as a management tool for tinnitus. Sound therapy have varying goals. Reducing the attention drawn to tinnitus, reducing the loudness of tinnitus, substituting a less disruptive noise. Sound therapy can be achieved with many modalities: Environmental Enrichment, tinnitus maskers, hearing aids and combination instruments such as: Danalogic iFIT Tinnitus, ReSound Live TS, Oticon’s Tinnitus “SoundSupport”, Phonak’s Tinnitus Balance and Widex Zen Fractal Tones. There are other sound devices e.g.: Acoustic Co-ordinated Reset, Neuromodulation, Serenade, Neuromonics, Phase-Out, Phase-shift and tinnitus inhibitory pathway activation. The advantages of sound therapy are: being non-invasive, reduce patient frustration and anxiety, some patients experience residual inhibition and it can facilitate patient’s habituation to tinnitus.

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Hearing profile in children with allergic rhinitis

Adekunle Adeyemo, Josephine Eziyi, Yemisi Amusa, Sanyaolu Ameye

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):10-13

Objective We carried out this study to determine the profile of hearing of children with allergic rhinitis compared with normal controls. Patients and methods Children with allergic rhinitis between the ages of 4 and 16 years attending the Otorhinolaryngology Clinics as well as age-matched and sex-matched controls were recruited into this study. We obtained the participants’ bio data, symptoms and duration using a structured interviewer questionnaire. We then carried out a pure tone audiometry on the participants. The degree of hearing loss was determined on the basis of the WHO standard classification. Results We recruited 99 children with clinical evidence of allergic rhinitis and an equal number of healthy controls completed the study. The mean age was 9.19±3.98 years in the test participants and 9.35±4.05 years in the controls, respectively. Mild hearing loss on the right side was more than twice as common among patients, 24 (24.2%), compared with the controls, 11(11.1%). Left-sided mild hearing loss was more than four times more prevalent among patients with allergic rhinitis, 26 (26.3%), compared with the controls, six (6.1%). Hearing threshold worse than 25 dB hearing level in the better-hearing ear was found to be significantly more prevalent among patients compared with the controls. Conclusion We could conclude that hearing is significantly worse in allergic children compared with controls, with disabling hearing loss being more significantly associated with allergic rhinitis.

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Comparison of two hearing aid fitting formulae in improving the patients’ satisfaction with amplification for experienced hearing aid users

Mohamed Shabana, Mona H Selim, Salwa M Abd El-Latif, Mona M Hamdy, Mai M El-Gohary

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):19-25

Introduction The effectiveness of real word satisfaction is very important for optimal hearing aid (HA) fitting, which can be assessed using self-report questionnaires. The Client Oriented Scale of Improvement (COSI) and Abbreviated Profile of Hearing Aid Benefit (APHAB) are useful tools for assessing the effectiveness of HA in achieving patient satisfaction. Patients and methods This study included 20 hearing-impaired adults. Their hearing thresholds ranged from moderate to moderately severe sensorineural hearing loss and had previous experience with HAs. Their ages ranged from 18 to 60 years, and the mean duration of HA experience was 3.85±5.02 years. Participants were examined in three scheduled sessions: unaided, aided National Acoustics Laboratories-Nonlinear 2 (NAL-NL2), and aided desired sensation level (DSL) v5. Each session was scheduled 2 months after the previous session. Patient satisfaction was assessed using the COSI and APHAB questionnaires for each HA fitting formulae. Results Both formulae have improved patient’s five client needs of the COSI; however, NAL-NL2 had better final ability score compared with DSL v5. Using the APHAB questionnaire, both formulae have decreased the listening difficulty score significantly. Using APHAB questionnaire, NAL-NL2 showed significantly less listening difficulty compared with DSL v5 as regards difficulties in ease of communication, broadband noise, and reverberation. However, both formulae did not improve ‘aversiveness’ conditions. Conclusion Questionnaires are equally important to audiometric tests and should not be underestimated and hence should be relied upon it in HA-fitting verification.

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Tympanometric assessment of Eustachian tube function as a prognostic indicator in myringoplasty

Suresh Babu Undavalli, Narayan Hanumanth Rao Kulkarni, Sukrit Bose, Anuradha Ananthaneni

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):14-18

Aim To determine eustachian tube function in tubo-tympanic type of chronic ear disease and correlate it with pathological changes in middle ear. Objective To ascertain whether eustachian tube function had any demeanor upon the outcome of myringoplasty. Backgound The prevailing interest in the patho-physiology of the eustachian tube has been stimulated by the persistent incidence of middle ear effusion and chronic otitis media. The ongoing sophistication in current middle ear reconstructive surgery has added more dimensions to the study of eustachian tube and its effects in the course of reconstructive middle ear surgery. One of the prime elements accountable for failure of reconstructive middle ear surgery has been tubal dysfunction. Method In the present study eustachian tube function was evaluated in in 30 patients who were undergoing myringoplasty for tubo-tympanic type of chronic suppurative otitis media having central perforation by tuning fork tests, microscopic evaluation of the middle ear mucosa and Impedance audiometry. Results 70% of the myringoplasty cases had good surgical outcome and of the 24 cases that had good eustation tube function 87.5% had successful surgical outcome remaining cases had recurrence of otorrhea. Conclusion The results were validating good eustachain tube function as a criterion for electing cases under middle ear reconstructive surgery and Impedance audiometer assures a superlative means of appraising Eustachain tube function.

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The role of antibiotics in treating secretory otitis media in children aged 2–12 years in an accredited teaching hospital in southeast Asia

Sarmishtha De, Kamal Kachhawa, Arun Gambhir, Rajesh K Jain, Rasmirekha Behera, Sanjay K Diwan, Sanjay Kumar

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):6-9

Introduction Secretory otitis media (SOM) is the most common clinical condition that can cause conductive deafness, especially among school-going children. The outcomes of hearing loss in children include speech problems, behavioral problems, and poor academic performance. Management of SOM therefore remains crucial. We carried out a comparative study of antibiotics versus surgical therapy for the treatment of SOM. Patients and methods The present study included 50 patients. Detailed history taking with ENT examinations was performed and documented in a validated pro forma. Routine investigations such as complete blood count, urine examination, audiological investigation such as impedance audiometry, etc, were carried out. Observation and results About 70% of the patients presented with symptoms of ear block with mouth breathing. Increased incidence was found in the 2–6 years age group. The present showed that surgery can increase the rate of recovery, shorten the duration of therapy, and prevent the recurrence of SOM compared with treatment with antibiotics. Conclusion Both the treatments have complications associated with them. Large, well-controlled studies can help resolve the risk–benefit ratio by measuring SOM recurrence, functional outcome, quality of life, and long-term outcomes.

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Sound therapy for tinnitus patients

Mohamed I Shabana, Abeir O Dabbous, Ayman M.M. Abdelkarim

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):1-5

Sound therapy, or use of any sound for the purposes of tinnitus management, is widely accepted as a management tool for tinnitus. Sound therapy have varying goals. Reducing the attention drawn to tinnitus, reducing the loudness of tinnitus, substituting a less disruptive noise. Sound therapy can be achieved with many modalities: Environmental Enrichment, tinnitus maskers, hearing aids and combination instruments such as: Danalogic iFIT Tinnitus, ReSound Live TS, Oticon’s Tinnitus “SoundSupport”, Phonak’s Tinnitus Balance and Widex Zen Fractal Tones. There are other sound devices e.g.: Acoustic Co-ordinated Reset, Neuromodulation, Serenade, Neuromonics, Phase-Out, Phase-shift and tinnitus inhibitory pathway activation. The advantages of sound therapy are: being non-invasive, reduce patient frustration and anxiety, some patients experience residual inhibition and it can facilitate patient’s habituation to tinnitus.

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Hearing profile in children with allergic rhinitis

Adekunle Adeyemo, Josephine Eziyi, Yemisi Amusa, Sanyaolu Ameye

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):10-13

Objective We carried out this study to determine the profile of hearing of children with allergic rhinitis compared with normal controls. Patients and methods Children with allergic rhinitis between the ages of 4 and 16 years attending the Otorhinolaryngology Clinics as well as age-matched and sex-matched controls were recruited into this study. We obtained the participants’ bio data, symptoms and duration using a structured interviewer questionnaire. We then carried out a pure tone audiometry on the participants. The degree of hearing loss was determined on the basis of the WHO standard classification. Results We recruited 99 children with clinical evidence of allergic rhinitis and an equal number of healthy controls completed the study. The mean age was 9.19±3.98 years in the test participants and 9.35±4.05 years in the controls, respectively. Mild hearing loss on the right side was more than twice as common among patients, 24 (24.2%), compared with the controls, 11(11.1%). Left-sided mild hearing loss was more than four times more prevalent among patients with allergic rhinitis, 26 (26.3%), compared with the controls, six (6.1%). Hearing threshold worse than 25 dB hearing level in the better-hearing ear was found to be significantly more prevalent among patients compared with the controls. Conclusion We could conclude that hearing is significantly worse in allergic children compared with controls, with disabling hearing loss being more significantly associated with allergic rhinitis.

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Comparison of two hearing aid fitting formulae in improving the patients’ satisfaction with amplification for experienced hearing aid users

Mohamed Shabana, Mona H Selim, Salwa M Abd El-Latif, Mona M Hamdy, Mai M El-Gohary

Advanced Arab Academy of Audio-Vestibulogy Journal 2017 4(1):19-25

Introduction The effectiveness of real word satisfaction is very important for optimal hearing aid (HA) fitting, which can be assessed using self-report questionnaires. The Client Oriented Scale of Improvement (COSI) and Abbreviated Profile of Hearing Aid Benefit (APHAB) are useful tools for assessing the effectiveness of HA in achieving patient satisfaction. Patients and methods This study included 20 hearing-impaired adults. Their hearing thresholds ranged from moderate to moderately severe sensorineural hearing loss and had previous experience with HAs. Their ages ranged from 18 to 60 years, and the mean duration of HA experience was 3.85±5.02 years. Participants were examined in three scheduled sessions: unaided, aided National Acoustics Laboratories-Nonlinear 2 (NAL-NL2), and aided desired sensation level (DSL) v5. Each session was scheduled 2 months after the previous session. Patient satisfaction was assessed using the COSI and APHAB questionnaires for each HA fitting formulae. Results Both formulae have improved patient’s five client needs of the COSI; however, NAL-NL2 had better final ability score compared with DSL v5. Using the APHAB questionnaire, both formulae have decreased the listening difficulty score significantly. Using APHAB questionnaire, NAL-NL2 showed significantly less listening difficulty compared with DSL v5 as regards difficulties in ease of communication, broadband noise, and reverberation. However, both formulae did not improve ‘aversiveness’ conditions. Conclusion Questionnaires are equally important to audiometric tests and should not be underestimated and hence should be relied upon it in HA-fitting verification.

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Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation–Second Edition

Purpose
Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of Articulation–Second Edition (GFTA-2) to identify candidates for a screening measure of speech sound production skills.
Method
The phoneme accuracies from 154 preschoolers, with speech skills on the GFTA-2 ranging from the 1st to above the 90th percentile, were analyzed with a 2-parameter logistic model.
Results
A total of 108 of the 232 phonemes from stimuli in the sounds-in-words subtest fit the IRT model. These phonemes, and subgroups of the most difficult of these phonemes, correlated significantly with the children's overall percentile scores on the GFTA-2. Regression equations calculated for the 5 and 10 most difficult phonemes predicted overall percentile score at levels commensurate with other screening measures.
Conclusions
These results suggest that speech production accuracy can be screened effectively with a small number of sounds. They motivate further research toward the development of a screening measure of children's speech sound production skills whose stimuli consist of a limited number of difficult phonemes.

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Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation–Second Edition

Purpose
Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of Articulation–Second Edition (GFTA-2) to identify candidates for a screening measure of speech sound production skills.
Method
The phoneme accuracies from 154 preschoolers, with speech skills on the GFTA-2 ranging from the 1st to above the 90th percentile, were analyzed with a 2-parameter logistic model.
Results
A total of 108 of the 232 phonemes from stimuli in the sounds-in-words subtest fit the IRT model. These phonemes, and subgroups of the most difficult of these phonemes, correlated significantly with the children's overall percentile scores on the GFTA-2. Regression equations calculated for the 5 and 10 most difficult phonemes predicted overall percentile score at levels commensurate with other screening measures.
Conclusions
These results suggest that speech production accuracy can be screened effectively with a small number of sounds. They motivate further research toward the development of a screening measure of children's speech sound production skills whose stimuli consist of a limited number of difficult phonemes.

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Applying Item Response Theory to the Development of a Screening Adaptation of the Goldman-Fristoe Test of Articulation–Second Edition

Purpose
Item response theory (IRT) is a psychometric approach to measurement that uses latent trait abilities (e.g., speech sound production skills) to model performance on individual items that vary by difficulty and discrimination. An IRT analysis was applied to preschoolers' productions of the words on the Goldman-Fristoe Test of Articulation–Second Edition (GFTA-2) to identify candidates for a screening measure of speech sound production skills.
Method
The phoneme accuracies from 154 preschoolers, with speech skills on the GFTA-2 ranging from the 1st to above the 90th percentile, were analyzed with a 2-parameter logistic model.
Results
A total of 108 of the 232 phonemes from stimuli in the sounds-in-words subtest fit the IRT model. These phonemes, and subgroups of the most difficult of these phonemes, correlated significantly with the children's overall percentile scores on the GFTA-2. Regression equations calculated for the 5 and 10 most difficult phonemes predicted overall percentile score at levels commensurate with other screening measures.
Conclusions
These results suggest that speech production accuracy can be screened effectively with a small number of sounds. They motivate further research toward the development of a screening measure of children's speech sound production skills whose stimuli consist of a limited number of difficult phonemes.

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Effects of Aging on Vocal Fundamental Frequency and Vowel Formants in Men and Women

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Publication date: Available online 30 August 2017
Source:Journal of Voice
Author(s): Julie Traub Eichhorn, Raymond D. Kent, Diane Austin, Houri K. Vorperian
PurposeThis study reports data on vocal fundamental frequency (fo) and the first four formant frequencies (F1, F2, F3, F4) for four vowels produced by speakers in three adult age cohorts, in a test of the null hypothesis that there are no age-related changes in these variables. Participants were 43 men and 53 women between the ages of 20 and 92 years.ResultsThe most consistent age-related effect was a decrease in fo for women. Significant differences in F1, F2, and F3 were vowel-specific for both sexes. No significant differences were observed for the highest formant F4.ConclusionsWomen experience a significant decrease in fo, which is likely related to menopause. Formant frequencies of the corner vowels change little across several decades of adult life, either because physiological aging has small effects on these variables or because individuals compensate for age-related changes in anatomy and physiology.



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A New Relationship

How I craved you in my youth. The bigger your roar, the less I could resist you. The harder you shook everything that was supposed to be stationary, the closer I moved in. I needed to experience you up close and personal. You brought the style to a musical gathering. If my cheeks did not tremble in your pressure wave, I was not close enough to the speakers or the stage. 



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Τετάρτη 30 Αυγούστου 2017

Understanding Hearing and Hearing Loss in Children With Down Syndrome

Purpose
This study evaluated the prevalence of permanent and transient hearing loss, the use of hearing aids as a recommendation, and middle ear dysfunction in children with Down syndrome (DS) through a large multiage and ethnically diverse sample, using current audiologic testing practices.
Method
Retrospective analysis of data collected on 308 children with DS (168 boys, 140 girls; average age = 5.99 ± 4.88 years) who received an audiological evaluation during 2013 as part of their medical care at a large pediatric hospital.
Results
Permanent hearing loss was identified in 24.9% of the children, among whom bilateral (75.4%) and conductive (33.3%) hearing losses occurred most often. Of children with DS, 22%–30% experienced a transient hearing loss, with a high incidence of middle ear pathologies from infancy until early adulthood. There were no statistical differences between ethnicity and permanent/transient hearing loss diagnosis. Twenty-three percent were current hearing aid users or had them recommended in a treatment plan.
Conclusions
The prevalence of hearing loss and abnormal middle ear status is high in the pediatric population with DS. Audiologic evaluations should follow the American Academy of Pediatrics practice guidelines to monitor this high-risk population, and amplification should be considered as an appropriate intervention option if repeated audiologic examinations reveal hearing loss.

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Understanding Hearing and Hearing Loss in Children With Down Syndrome

Purpose
This study evaluated the prevalence of permanent and transient hearing loss, the use of hearing aids as a recommendation, and middle ear dysfunction in children with Down syndrome (DS) through a large multiage and ethnically diverse sample, using current audiologic testing practices.
Method
Retrospective analysis of data collected on 308 children with DS (168 boys, 140 girls; average age = 5.99 ± 4.88 years) who received an audiological evaluation during 2013 as part of their medical care at a large pediatric hospital.
Results
Permanent hearing loss was identified in 24.9% of the children, among whom bilateral (75.4%) and conductive (33.3%) hearing losses occurred most often. Of children with DS, 22%–30% experienced a transient hearing loss, with a high incidence of middle ear pathologies from infancy until early adulthood. There were no statistical differences between ethnicity and permanent/transient hearing loss diagnosis. Twenty-three percent were current hearing aid users or had them recommended in a treatment plan.
Conclusions
The prevalence of hearing loss and abnormal middle ear status is high in the pediatric population with DS. Audiologic evaluations should follow the American Academy of Pediatrics practice guidelines to monitor this high-risk population, and amplification should be considered as an appropriate intervention option if repeated audiologic examinations reveal hearing loss.

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Understanding Hearing and Hearing Loss in Children With Down Syndrome

Purpose
This study evaluated the prevalence of permanent and transient hearing loss, the use of hearing aids as a recommendation, and middle ear dysfunction in children with Down syndrome (DS) through a large multiage and ethnically diverse sample, using current audiologic testing practices.
Method
Retrospective analysis of data collected on 308 children with DS (168 boys, 140 girls; average age = 5.99 ± 4.88 years) who received an audiological evaluation during 2013 as part of their medical care at a large pediatric hospital.
Results
Permanent hearing loss was identified in 24.9% of the children, among whom bilateral (75.4%) and conductive (33.3%) hearing losses occurred most often. Of children with DS, 22%–30% experienced a transient hearing loss, with a high incidence of middle ear pathologies from infancy until early adulthood. There were no statistical differences between ethnicity and permanent/transient hearing loss diagnosis. Twenty-three percent were current hearing aid users or had them recommended in a treatment plan.
Conclusions
The prevalence of hearing loss and abnormal middle ear status is high in the pediatric population with DS. Audiologic evaluations should follow the American Academy of Pediatrics practice guidelines to monitor this high-risk population, and amplification should be considered as an appropriate intervention option if repeated audiologic examinations reveal hearing loss.

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Training Peer Partners to Use a Speech-Generating Device With Classmates With Autism Spectrum Disorder: Exploring Communication Outcomes Across Preschool Contexts

Purpose
This study examined effects of a peer-mediated intervention that provided training on the use of a speech-generating device for preschoolers with severe autism spectrum disorder (ASD) and peer partners.
Method
Effects were examined using a multiple probe design across 3 children with ASD and limited to no verbal skills. Three peers without disabilities were taught to Stay, Play, and Talk using a GoTalk 4+ (Attainment Company) and were then paired up with a classmate with ASD in classroom social activities. Measures included rates of communication acts, communication mode and function, reciprocity, and engagement with peers.
Results
Following peer training, intervention effects were replicated across 3 peers, who all demonstrated an increased level and upward trend in communication acts to their classmates with ASD. Outcomes also revealed moderate intervention effects and increased levels of peer-directed communication for 3 children with ASD in classroom centers. Additional analyses revealed higher rates of communication in the added context of preferred toys and snack. The children with ASD also demonstrated improved communication reciprocity and peer engagement.
Conclusions
Results provide preliminary evidence on the benefits of combining peer-mediated and speech-generating device interventions to improve children's communication. Furthermore, it appears that preferred contexts are likely to facilitate greater communication and social engagement with peers.

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Distributed Training Enhances Implicit Sequence Acquisition in Children With Specific Language Impairment

Purpose
This study explored the effects of 2 different training structures on the implicit acquisition of a sequence in a serial reaction time (SRT) task in children with and without specific language impairment (SLI).
Method
All of the children underwent 3 training sessions, followed by a retention session 2 weeks after the last session. In the massed-training condition, the 3 training sessions were in immediate succession on 1 day, whereas in the distributed-training condition, the 3 training sessions were spread over a 1-week period in an expanding schedule format.
Results
Statistical analyses showed that the children with normal language were unaffected by the training conditions, performing the SRT task similarly in both training conditions. The children with SLI, however, were affected by the training structure, performing the SRT task better when the training sessions were spaced over time rather than clustered on 1 day.
Conclusion
This study demonstrated that although intensive training does not increase learning in children with SLI, distributing training sessions over time does increase learning. The implications of these results on the learning abilities of children with SLI are discussed, as are the mechanisms involved in massed versus distributed learning.

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Training Peer Partners to Use a Speech-Generating Device With Classmates With Autism Spectrum Disorder: Exploring Communication Outcomes Across Preschool Contexts

Purpose
This study examined effects of a peer-mediated intervention that provided training on the use of a speech-generating device for preschoolers with severe autism spectrum disorder (ASD) and peer partners.
Method
Effects were examined using a multiple probe design across 3 children with ASD and limited to no verbal skills. Three peers without disabilities were taught to Stay, Play, and Talk using a GoTalk 4+ (Attainment Company) and were then paired up with a classmate with ASD in classroom social activities. Measures included rates of communication acts, communication mode and function, reciprocity, and engagement with peers.
Results
Following peer training, intervention effects were replicated across 3 peers, who all demonstrated an increased level and upward trend in communication acts to their classmates with ASD. Outcomes also revealed moderate intervention effects and increased levels of peer-directed communication for 3 children with ASD in classroom centers. Additional analyses revealed higher rates of communication in the added context of preferred toys and snack. The children with ASD also demonstrated improved communication reciprocity and peer engagement.
Conclusions
Results provide preliminary evidence on the benefits of combining peer-mediated and speech-generating device interventions to improve children's communication. Furthermore, it appears that preferred contexts are likely to facilitate greater communication and social engagement with peers.

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Distributed Training Enhances Implicit Sequence Acquisition in Children With Specific Language Impairment

Purpose
This study explored the effects of 2 different training structures on the implicit acquisition of a sequence in a serial reaction time (SRT) task in children with and without specific language impairment (SLI).
Method
All of the children underwent 3 training sessions, followed by a retention session 2 weeks after the last session. In the massed-training condition, the 3 training sessions were in immediate succession on 1 day, whereas in the distributed-training condition, the 3 training sessions were spread over a 1-week period in an expanding schedule format.
Results
Statistical analyses showed that the children with normal language were unaffected by the training conditions, performing the SRT task similarly in both training conditions. The children with SLI, however, were affected by the training structure, performing the SRT task better when the training sessions were spaced over time rather than clustered on 1 day.
Conclusion
This study demonstrated that although intensive training does not increase learning in children with SLI, distributing training sessions over time does increase learning. The implications of these results on the learning abilities of children with SLI are discussed, as are the mechanisms involved in massed versus distributed learning.

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Training Peer Partners to Use a Speech-Generating Device With Classmates With Autism Spectrum Disorder: Exploring Communication Outcomes Across Preschool Contexts

Purpose
This study examined effects of a peer-mediated intervention that provided training on the use of a speech-generating device for preschoolers with severe autism spectrum disorder (ASD) and peer partners.
Method
Effects were examined using a multiple probe design across 3 children with ASD and limited to no verbal skills. Three peers without disabilities were taught to Stay, Play, and Talk using a GoTalk 4+ (Attainment Company) and were then paired up with a classmate with ASD in classroom social activities. Measures included rates of communication acts, communication mode and function, reciprocity, and engagement with peers.
Results
Following peer training, intervention effects were replicated across 3 peers, who all demonstrated an increased level and upward trend in communication acts to their classmates with ASD. Outcomes also revealed moderate intervention effects and increased levels of peer-directed communication for 3 children with ASD in classroom centers. Additional analyses revealed higher rates of communication in the added context of preferred toys and snack. The children with ASD also demonstrated improved communication reciprocity and peer engagement.
Conclusions
Results provide preliminary evidence on the benefits of combining peer-mediated and speech-generating device interventions to improve children's communication. Furthermore, it appears that preferred contexts are likely to facilitate greater communication and social engagement with peers.

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Distributed Training Enhances Implicit Sequence Acquisition in Children With Specific Language Impairment

Purpose
This study explored the effects of 2 different training structures on the implicit acquisition of a sequence in a serial reaction time (SRT) task in children with and without specific language impairment (SLI).
Method
All of the children underwent 3 training sessions, followed by a retention session 2 weeks after the last session. In the massed-training condition, the 3 training sessions were in immediate succession on 1 day, whereas in the distributed-training condition, the 3 training sessions were spread over a 1-week period in an expanding schedule format.
Results
Statistical analyses showed that the children with normal language were unaffected by the training conditions, performing the SRT task similarly in both training conditions. The children with SLI, however, were affected by the training structure, performing the SRT task better when the training sessions were spaced over time rather than clustered on 1 day.
Conclusion
This study demonstrated that although intensive training does not increase learning in children with SLI, distributing training sessions over time does increase learning. The implications of these results on the learning abilities of children with SLI are discussed, as are the mechanisms involved in massed versus distributed learning.

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Preliminary evaluation of a novel non-linear frequency compression scheme for use in children

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Preliminary evaluation of a novel non-linear frequency compression scheme for use in children

.


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Preliminary evaluation of a novel non-linear frequency compression scheme for use in children

.


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Preliminary evaluation of a novel non-linear frequency compression scheme for use in children

.


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Preliminary evaluation of a novel non-linear frequency compression scheme for use in children

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NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy.

Related Articles

NLRP3 mutation and cochlear autoinflammation cause syndromic and nonsyndromic hearing loss DFNA34 responsive to anakinra therapy.

Proc Natl Acad Sci U S A. 2017 Aug 28;:

Authors: Nakanishi H, Kawashima Y, Kurima K, Chae JJ, Ross AM, Pinto-Patarroyo G, Patel SK, Muskett JA, Ratay JS, Chattaraj P, Park YH, Grevich S, Brewer CC, Hoa M, Kim HJ, Butman JA, Broderick L, Hoffman HM, Aksentijevich I, Kastner DL, Goldbach-Mansky R, Griffith AJ

Abstract
The NLRP3 inflammasome is an intracellular innate immune sensor that is expressed in immune cells, including monocytes and macrophages. Activation of the NLRP3 inflammasome leads to IL-1β secretion. Gain-of-function mutations of NLRP3 result in abnormal activation of the NLRP3 inflammasome, and cause the autosomal dominant systemic autoinflammatory disease spectrum, termed cryopyrin-associated periodic syndromes (CAPS). Here, we show that a missense mutation, p.Arg918Gln (c.2753G > A), of NLRP3 causes autosomal-dominant sensorineural hearing loss in two unrelated families. In family LMG446, hearing loss is accompanied by autoinflammatory signs and symptoms without serologic evidence of inflammation as part of an atypical CAPS phenotype and was reversed or improved by IL-1β blockade therapy. In family LMG113, hearing loss segregates without any other target-organ manifestations of CAPS. This observation led us to explore the possibility that resident macrophage/monocyte-like cells in the cochlea can mediate local autoinflammation via activation of the NLRP3 inflammasome. The NLRP3 inflammasome can indeed be activated in resident macrophage/monocyte-like cells in the mouse cochlea, resulting in secretion of IL-1β. This pathway could underlie treatable sensorineural hearing loss in DFNA34, CAPS, and possibly in a wide variety of hearing-loss disorders, such as sudden sensorineural hearing loss and Meniere's disease that are elicited by pathogens and processes that stimulate innate immune responses within the cochlea.

PMID: 28847925 [PubMed - as supplied by publisher]



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Succinyl-CoA synthetase (SUCLA2) deficiency in two siblings with impaired activity of other mitochondrial oxidative enzymes in skeletal muscle without mitochondrial DNA depletion.

http:--linkinghub.elsevier.com-ihub-imag Related Articles

Succinyl-CoA synthetase (SUCLA2) deficiency in two siblings with impaired activity of other mitochondrial oxidative enzymes in skeletal muscle without mitochondrial DNA depletion.

Mol Genet Metab. 2017 Mar;120(3):213-222

Authors: Huang X, Bedoyan JK, Demirbas D, Harris DJ, Miron A, Edelheit S, Grahame G, DeBrosse SD, Wong LJ, Hoppel CL, Kerr DS, Anselm I, Berry GT

Abstract
Mutations in SUCLA2 result in succinyl-CoA ligase (ATP-forming) or succinyl-CoA synthetase (ADP-forming) (A-SCS) deficiency, a mitochondrial tricarboxylic acid cycle disorder. The phenotype associated with this gene defect is largely encephalomyopathy. We describe two siblings compound heterozygous for SUCLA2 mutations, c.985A>G (p.M329V) and c.920C>T (p.A307V), with parents confirmed as carriers of each mutation. We developed a new LC-MS/MS based enzyme assay to demonstrate the decreased SCS activity in the siblings with this unique genotype. Both siblings shared bilateral progressive hearing loss, encephalopathy, global developmental delay, generalized myopathy, and dystonia with choreoathetosis. Prior to diagnosis and because of lactic acidosis and low activity of muscle pyruvate dehydrogenase complex (PDC), sibling 1 (S1) was placed on dichloroacetate, while sibling 2 (S2) was on a ketogenic diet. S1 developed severe cyclic vomiting refractory to therapy, while S2 developed Leigh syndrome, severe GI dysmotility, intermittent anemia, hypogammaglobulinemia and eventually succumbed to his disorder. The mitochondrial DNA contents in skeletal muscle (SM) were normal in both siblings. Pyruvate dehydrogenase complex, ketoglutarate dehydrogenase complex, and several mitochondrial electron transport chain (ETC) activities were low or at the low end of the reference range in frozen SM from S1 and/or S2. In contrast, activities of PDC, other mitochondrial enzymes of pyruvate metabolism, ETC and, integrated oxidative phosphorylation, in skin fibroblasts were not significantly impaired. Although we show that propionyl-CoA inhibits PDC, it does not appear to account for decreased PDC activity in SM. A better understanding of the mechanisms of phenotypic variability and the etiology for tissue-specific secondary deficiencies of mitochondrial enzymes of oxidative metabolism, and independently mitochondrial DNA depletion (common in other cases of A-SCS deficiency), is needed given the implications for control of lactic acidosis and possible clinical management.

PMID: 27913098 [PubMed - indexed for MEDLINE]



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Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.

Related Articles

Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.

Cold Spring Harb Perspect Biol. 2017 Aug 28;:

Authors: Jaiganesh A, Narui Y, Araya-Secchi R, Sotomayor M

Abstract
Cadherins form a large family of proteins often involved in calcium-dependent cellular adhesion. Although classical members of the family can provide a physical bond between cells, a subset of special cadherins use their extracellular domains to interlink apical specializations of single epithelial sensory cells. Two of these cadherins, cadherin-23 (CDH23) and protocadherin-15 (PCDH15), form extracellular "tip link" filaments that connect apical bundles of stereocilia on hair cells essential for inner-ear mechanotransduction. As these bundles deflect in response to mechanical stimuli from sound or head movements, tip links gate hair-cell mechanosensitive channels to initiate sensory perception. Here, we review the unusual and diverse structural properties of these tip-link cadherins and the functional significance of their deafness-related missense mutations. Based on the structural features of CDH23 and PCDH15, we discuss the elasticity of tip links and models that bridge the gap between the nanomechanics of cadherins and the micromechanics of hair-cell bundles during inner-ear mechanotransduction.

PMID: 28847902 [PubMed - as supplied by publisher]



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Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.

Related Articles

Beyond Cell-Cell Adhesion: Sensational Cadherins for Hearing and Balance.

Cold Spring Harb Perspect Biol. 2017 Aug 28;:

Authors: Jaiganesh A, Narui Y, Araya-Secchi R, Sotomayor M

Abstract
Cadherins form a large family of proteins often involved in calcium-dependent cellular adhesion. Although classical members of the family can provide a physical bond between cells, a subset of special cadherins use their extracellular domains to interlink apical specializations of single epithelial sensory cells. Two of these cadherins, cadherin-23 (CDH23) and protocadherin-15 (PCDH15), form extracellular "tip link" filaments that connect apical bundles of stereocilia on hair cells essential for inner-ear mechanotransduction. As these bundles deflect in response to mechanical stimuli from sound or head movements, tip links gate hair-cell mechanosensitive channels to initiate sensory perception. Here, we review the unusual and diverse structural properties of these tip-link cadherins and the functional significance of their deafness-related missense mutations. Based on the structural features of CDH23 and PCDH15, we discuss the elasticity of tip links and models that bridge the gap between the nanomechanics of cadherins and the micromechanics of hair-cell bundles during inner-ear mechanotransduction.

PMID: 28847902 [PubMed - as supplied by publisher]



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Dual-Task Walking Performance in Older Persons With Hearing Impairment: Implications for Interventions From a Preliminary Observational Study.

Objectives: Adults with "hearing loss" have an increased falls risks. There may be an association between hearing impairment and walking performance under dual-task (DT) and triple-task (TT) conditions. The aim of this study was to identify DT and TT effects on walking speed, step length, and cadence in adults with hearing impairment, previous falls, and physical limitations. Design: The observational study included 73 community-dwelling older people seeking audiology services. Data were collected on sociodemographic characteristics, previous falls, fear of falling, physical limitations, and walking performance under three task conditions. Differences between the task conditions (single task [ST], DT, and TT) and the hearing groups were analyzed with a two-way ANOVA with repeated measures. The influence of fall risks and limited physical functioning on walking under ST, DT, and TT conditions was analyzed with ANOVAs, with ST, DT, and TT performance as repeated measurement factor (i.e., walking speed, step length and Cadence x Previous falls, or short physical performance battery

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Stability of Auditory Steady State Responses Over Time.

Objectives: Auditory steady state responses (ASSRs) are used in clinical practice for objective hearing assessments. The response is called steady state because it is assumed to be stable over time, and because it is evoked by a stimulus with a certain periodicity, which will lead to discrete frequency components that are stable in amplitude and phase over time. However, the stimuli commonly used to evoke ASSRs are also known to be able to induce loudness adaptation behaviorally. Researchers and clinicians using ASSRs assume that the response remains stable over time. This study investigates (1) the stability of ASSR amplitudes over time, within one recording, and (2) whether loudness adaptation can be reflected in ASSRs. Design: ASSRs were measured from 14 normal-hearing participants. The ASSRs were evoked by the stimuli that caused the most loudness adaptation in a previous behavioral study, that is, mixed-modulated sinusoids with carrier frequencies of either 500 or 2000 Hz, a modulation frequency of 40 Hz, and a low sensation level of 30 dB SL. For each carrier frequency and participant, 40 repetitions of 92 sec recordings were made. Two types of analyses were used to investigate the ASSR amplitudes over time: with the more traditionally used Fast Fourier Transform and with a novel Kalman filtering approach. Robust correlations between the ASSR amplitudes and behavioral loudness adaptation ratings were also calculated. Results: Overall, ASSR amplitudes were stable. Over all individual recordings, the median change of the amplitudes over time was -0.0001 [mu]V/s. Based on group analysis, a significant but very weak decrease in amplitude over time was found, with the decrease in amplitude over time around -0.0002 [mu]V/s. Correlation coefficients between ASSR amplitudes and behavioral loudness adaptation ratings were significant but low to moderate, with r = 0.27 and r = 0.39 for the 500 and 2000 Hz carrier frequency, respectively. Conclusions: The decrease in amplitude of ASSRs over time (92 sec) is small. Consequently, it is safe to use ASSRs in clinical practice, and additional correction factors for objective hearing assessments are not needed. Because only small decreases in amplitudes were found, loudness adaptation is probably not reflected by the ASSRs. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Dual-Task Walking Performance in Older Persons With Hearing Impairment: Implications for Interventions From a Preliminary Observational Study.

Objectives: Adults with "hearing loss" have an increased falls risks. There may be an association between hearing impairment and walking performance under dual-task (DT) and triple-task (TT) conditions. The aim of this study was to identify DT and TT effects on walking speed, step length, and cadence in adults with hearing impairment, previous falls, and physical limitations. Design: The observational study included 73 community-dwelling older people seeking audiology services. Data were collected on sociodemographic characteristics, previous falls, fear of falling, physical limitations, and walking performance under three task conditions. Differences between the task conditions (single task [ST], DT, and TT) and the hearing groups were analyzed with a two-way ANOVA with repeated measures. The influence of fall risks and limited physical functioning on walking under ST, DT, and TT conditions was analyzed with ANOVAs, with ST, DT, and TT performance as repeated measurement factor (i.e., walking speed, step length and Cadence x Previous falls, or short physical performance battery

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Stability of Auditory Steady State Responses Over Time.

Objectives: Auditory steady state responses (ASSRs) are used in clinical practice for objective hearing assessments. The response is called steady state because it is assumed to be stable over time, and because it is evoked by a stimulus with a certain periodicity, which will lead to discrete frequency components that are stable in amplitude and phase over time. However, the stimuli commonly used to evoke ASSRs are also known to be able to induce loudness adaptation behaviorally. Researchers and clinicians using ASSRs assume that the response remains stable over time. This study investigates (1) the stability of ASSR amplitudes over time, within one recording, and (2) whether loudness adaptation can be reflected in ASSRs. Design: ASSRs were measured from 14 normal-hearing participants. The ASSRs were evoked by the stimuli that caused the most loudness adaptation in a previous behavioral study, that is, mixed-modulated sinusoids with carrier frequencies of either 500 or 2000 Hz, a modulation frequency of 40 Hz, and a low sensation level of 30 dB SL. For each carrier frequency and participant, 40 repetitions of 92 sec recordings were made. Two types of analyses were used to investigate the ASSR amplitudes over time: with the more traditionally used Fast Fourier Transform and with a novel Kalman filtering approach. Robust correlations between the ASSR amplitudes and behavioral loudness adaptation ratings were also calculated. Results: Overall, ASSR amplitudes were stable. Over all individual recordings, the median change of the amplitudes over time was -0.0001 [mu]V/s. Based on group analysis, a significant but very weak decrease in amplitude over time was found, with the decrease in amplitude over time around -0.0002 [mu]V/s. Correlation coefficients between ASSR amplitudes and behavioral loudness adaptation ratings were significant but low to moderate, with r = 0.27 and r = 0.39 for the 500 and 2000 Hz carrier frequency, respectively. Conclusions: The decrease in amplitude of ASSRs over time (92 sec) is small. Consequently, it is safe to use ASSRs in clinical practice, and additional correction factors for objective hearing assessments are not needed. Because only small decreases in amplitudes were found, loudness adaptation is probably not reflected by the ASSRs. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Dual-Task Walking Performance in Older Persons With Hearing Impairment: Implications for Interventions From a Preliminary Observational Study.

Objectives: Adults with "hearing loss" have an increased falls risks. There may be an association between hearing impairment and walking performance under dual-task (DT) and triple-task (TT) conditions. The aim of this study was to identify DT and TT effects on walking speed, step length, and cadence in adults with hearing impairment, previous falls, and physical limitations. Design: The observational study included 73 community-dwelling older people seeking audiology services. Data were collected on sociodemographic characteristics, previous falls, fear of falling, physical limitations, and walking performance under three task conditions. Differences between the task conditions (single task [ST], DT, and TT) and the hearing groups were analyzed with a two-way ANOVA with repeated measures. The influence of fall risks and limited physical functioning on walking under ST, DT, and TT conditions was analyzed with ANOVAs, with ST, DT, and TT performance as repeated measurement factor (i.e., walking speed, step length and Cadence x Previous falls, or short physical performance battery

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Stability of Auditory Steady State Responses Over Time.

Objectives: Auditory steady state responses (ASSRs) are used in clinical practice for objective hearing assessments. The response is called steady state because it is assumed to be stable over time, and because it is evoked by a stimulus with a certain periodicity, which will lead to discrete frequency components that are stable in amplitude and phase over time. However, the stimuli commonly used to evoke ASSRs are also known to be able to induce loudness adaptation behaviorally. Researchers and clinicians using ASSRs assume that the response remains stable over time. This study investigates (1) the stability of ASSR amplitudes over time, within one recording, and (2) whether loudness adaptation can be reflected in ASSRs. Design: ASSRs were measured from 14 normal-hearing participants. The ASSRs were evoked by the stimuli that caused the most loudness adaptation in a previous behavioral study, that is, mixed-modulated sinusoids with carrier frequencies of either 500 or 2000 Hz, a modulation frequency of 40 Hz, and a low sensation level of 30 dB SL. For each carrier frequency and participant, 40 repetitions of 92 sec recordings were made. Two types of analyses were used to investigate the ASSR amplitudes over time: with the more traditionally used Fast Fourier Transform and with a novel Kalman filtering approach. Robust correlations between the ASSR amplitudes and behavioral loudness adaptation ratings were also calculated. Results: Overall, ASSR amplitudes were stable. Over all individual recordings, the median change of the amplitudes over time was -0.0001 [mu]V/s. Based on group analysis, a significant but very weak decrease in amplitude over time was found, with the decrease in amplitude over time around -0.0002 [mu]V/s. Correlation coefficients between ASSR amplitudes and behavioral loudness adaptation ratings were significant but low to moderate, with r = 0.27 and r = 0.39 for the 500 and 2000 Hz carrier frequency, respectively. Conclusions: The decrease in amplitude of ASSRs over time (92 sec) is small. Consequently, it is safe to use ASSRs in clinical practice, and additional correction factors for objective hearing assessments are not needed. Because only small decreases in amplitudes were found, loudness adaptation is probably not reflected by the ASSRs. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.

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Τρίτη 29 Αυγούστου 2017

Texas Department of Licensing and Regulation for Out-of-State Health-Care Providers Assisting with Disaster Response

In accordance with Section 418.016 of the Texas Government Code, Governor Greg Abbott has temporarily suspended all necessary statutes and rules to allow licensed health-care providers employed by a hospital and who are in good standing in another state to practice in Texas to assist with disaster response operations. 

This suspension is in effect until terminated by the Office of the Governor or until the Hurricane Harvey disaster declaration is lifted or expires.



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Auditory Training Schedules: What Is the Best Strategy?

Are the outcomes of an auditory training (AT) program better if the training is intensive and done close together in time (i.e., massed) or spread apart (i.e., spaced)? Tye-Murray et al (2017) attempted to answer this question.



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Δευτέρα 28 Αυγούστου 2017

How to Enjoy a Holiday Weekend

With Labor Day right around the corner, many of us may be planning some much-needed time away from the office. Are you able to truly relax and leave work behind when you are on vacation? Not everyone is able to stop thinking about work when they are not in the office. If this sounds like you, you may want to check out Art Markman's Harvard Business Review article titled “How to Forget About Work When You're Not Working.”



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Κυριακή 27 Αυγούστου 2017

Laryngeal Manual Therapies for Behavioral Dysphonia: A Systematic Review and Meta-analysis

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Publication date: Available online 26 August 2017
Source:Journal of Voice
Author(s): Vanessa Veis Ribeiro, Vanessa Pedrosa, Kelly Cristina Alves Silverio, Mara Behlau
ObjectivesThe aim of this study was to review systematically the literature and to analyze the effectiveness of laryngeal manual therapy in addressing the overall severity of vocal deviation, the intensity of vocal and laryngeal symptoms, and musculoskeletal pain in adults with behavioral dysphonia.Study DesignThis is a systematic review and meta-analysis.MethodsTwo independent authors selected clinical trials that analyzed the effectiveness of laryngeal manual therapy compared with other interventions in the treatment of adults with behavioral dysphonia from the Cochrane Library, PubMed, Web of Science, and LILACS. The analyzed outcomes were the overall severity of vocal deviation, the intensity of vocal and laryngeal symptoms, and musculoskeletal pain. Data analysis was conducted based on the following steps: the assessment of the risk of bias, the measures of treatment effect and descriptive data analysis, the assessment of heterogeneity, subgroup analysis, sensitivity analysis, and the assessment of reporting biases.ResultsA total of 2135 studies were identified, three of which met the selection criteria. Data analysis showed an unclear risk of 100% of performance bias and 66% of detection bias, in addition to a 33% high risk of selection bias. Low statistical and clinical heterogeneities were found. In addition, no significant difference was found in the relative risk of improvement with laryngeal manual therapy and with other interventions in the analyzed outcomes.ConclusionsVarious types of laryngeal manual therapies are available with similar objectives and effects, but their effectiveness is equivalent to that of other interventions involving direct voice therapy in the rehabilitation of adults with behavioral dysphonia.



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Σάββατο 26 Αυγούστου 2017

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Related Articles

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Int J Audiol. 2017 Aug 24;:1-8

Authors: Goehring T, Chapman JL, Bleeck S, Monaghan JJM

Abstract
OBJECTIVE: Processing delay is one of the important factors that limit the development of novel algorithms for hearing devices. In this study, both normal-hearing listeners and listeners with hearing loss were tested for their tolerance of processing delay up to 50 ms using a real-time setup for own-voice and external-voice conditions based on linear processing to avoid confounding effects of time-dependent gain.
DESIGN: Participants rated their perceived subjective annoyance for each condition on a 7-point Likert scale.
STUDY SAMPLE: Twenty normal-hearing participants and twenty participants with a range of mild to moderate hearing losses.
RESULTS: Delay tolerance was significantly greater for the participants with hearing loss in two out of three voice conditions. The average slopes of annoyance ratings were negatively correlated with the degree of hearing loss across participants. A small trend of higher tolerance of delay by experienced users of hearing aids in comparison to new users was not significant.
CONCLUSION: The increased tolerance of processing delay for speech production and perception with hearing loss and reduced sensitivity to changes in delay with stronger hearing loss may be beneficial for novel algorithms for hearing devices but the setup used in this study differed from commercial hearing aids.

PMID: 28838277 [PubMed - as supplied by publisher]



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Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Related Articles

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Int J Audiol. 2017 Aug 24;:1-8

Authors: Goehring T, Chapman JL, Bleeck S, Monaghan JJM

Abstract
OBJECTIVE: Processing delay is one of the important factors that limit the development of novel algorithms for hearing devices. In this study, both normal-hearing listeners and listeners with hearing loss were tested for their tolerance of processing delay up to 50 ms using a real-time setup for own-voice and external-voice conditions based on linear processing to avoid confounding effects of time-dependent gain.
DESIGN: Participants rated their perceived subjective annoyance for each condition on a 7-point Likert scale.
STUDY SAMPLE: Twenty normal-hearing participants and twenty participants with a range of mild to moderate hearing losses.
RESULTS: Delay tolerance was significantly greater for the participants with hearing loss in two out of three voice conditions. The average slopes of annoyance ratings were negatively correlated with the degree of hearing loss across participants. A small trend of higher tolerance of delay by experienced users of hearing aids in comparison to new users was not significant.
CONCLUSION: The increased tolerance of processing delay for speech production and perception with hearing loss and reduced sensitivity to changes in delay with stronger hearing loss may be beneficial for novel algorithms for hearing devices but the setup used in this study differed from commercial hearing aids.

PMID: 28838277 [PubMed - as supplied by publisher]



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Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Related Articles

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Int J Audiol. 2017 Aug 24;:1-8

Authors: Goehring T, Chapman JL, Bleeck S, Monaghan JJM

Abstract
OBJECTIVE: Processing delay is one of the important factors that limit the development of novel algorithms for hearing devices. In this study, both normal-hearing listeners and listeners with hearing loss were tested for their tolerance of processing delay up to 50 ms using a real-time setup for own-voice and external-voice conditions based on linear processing to avoid confounding effects of time-dependent gain.
DESIGN: Participants rated their perceived subjective annoyance for each condition on a 7-point Likert scale.
STUDY SAMPLE: Twenty normal-hearing participants and twenty participants with a range of mild to moderate hearing losses.
RESULTS: Delay tolerance was significantly greater for the participants with hearing loss in two out of three voice conditions. The average slopes of annoyance ratings were negatively correlated with the degree of hearing loss across participants. A small trend of higher tolerance of delay by experienced users of hearing aids in comparison to new users was not significant.
CONCLUSION: The increased tolerance of processing delay for speech production and perception with hearing loss and reduced sensitivity to changes in delay with stronger hearing loss may be beneficial for novel algorithms for hearing devices but the setup used in this study differed from commercial hearing aids.

PMID: 28838277 [PubMed - as supplied by publisher]



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via IFTTT

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Related Articles

Tolerable delay for speech production and perception: effects of hearing ability and experience with hearing aids.

Int J Audiol. 2017 Aug 24;:1-8

Authors: Goehring T, Chapman JL, Bleeck S, Monaghan JJM

Abstract
OBJECTIVE: Processing delay is one of the important factors that limit the development of novel algorithms for hearing devices. In this study, both normal-hearing listeners and listeners with hearing loss were tested for their tolerance of processing delay up to 50 ms using a real-time setup for own-voice and external-voice conditions based on linear processing to avoid confounding effects of time-dependent gain.
DESIGN: Participants rated their perceived subjective annoyance for each condition on a 7-point Likert scale.
STUDY SAMPLE: Twenty normal-hearing participants and twenty participants with a range of mild to moderate hearing losses.
RESULTS: Delay tolerance was significantly greater for the participants with hearing loss in two out of three voice conditions. The average slopes of annoyance ratings were negatively correlated with the degree of hearing loss across participants. A small trend of higher tolerance of delay by experienced users of hearing aids in comparison to new users was not significant.
CONCLUSION: The increased tolerance of processing delay for speech production and perception with hearing loss and reduced sensitivity to changes in delay with stronger hearing loss may be beneficial for novel algorithms for hearing devices but the setup used in this study differed from commercial hearing aids.

PMID: 28838277 [PubMed - as supplied by publisher]



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More Infants are Benefiting from Newborn Hearing Screenings

A CDC Morbidity and Mortality Weekly Report found more infants are receiving documented newborn hearing screening and early intervention services. (2017;66[33]:888.) National early hearing detection and intervention (EHDI) data showed that the percentage of newborns who had documented newborn hearing screening increased from 52 percent to over 97 percent between 2000 and 2014. From 2005 to 2014, documented enrollment in early intervention from 2005 to 2014 among newborns who received documented screening increased from 58 percent to 65 percent. The number of infants lost to follow-up reduced both overall and in selected states. For example, only 4.6 percent of infants who did not pass newborn hearing screening in Massachusetts in 2014 were lost to follow-up, and 85 percent of newborns with diagnosed hearing loss were documented to have received intervention services.

​Early diagnosis of hearing loss, starting with newborn screening, has been shown to reduce deficits in receptive and expressive language that occur in unscreened children who subsequently receive a clinical diagnosis of hearing loss. (Pediatrics. 2016;137[1].) The authors of the report hope the lessons learned from the success of newborn hearing screening programs could be applied to early detection and intervention initiatives for critical congenital heart disease and other health conditions.​

Published: 8/25/2017 2:44:00 PM


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More Infants are Benefiting from Newborn Hearing Screenings

A CDC Morbidity and Mortality Weekly Report found more infants are receiving documented newborn hearing screening and early intervention services. (2017;66[33]:888.) National early hearing detection and intervention (EHDI) data showed that the percentage of newborns who had documented newborn hearing screening increased from 52 percent to over 97 percent between 2000 and 2014. From 2005 to 2014, documented enrollment in early intervention from 2005 to 2014 among newborns who received documented screening increased from 58 percent to 65 percent. The number of infants lost to follow-up reduced both overall and in selected states. For example, only 4.6 percent of infants who did not pass newborn hearing screening in Massachusetts in 2014 were lost to follow-up, and 85 percent of newborns with diagnosed hearing loss were documented to have received intervention services.

​Early diagnosis of hearing loss, starting with newborn screening, has been shown to reduce deficits in receptive and expressive language that occur in unscreened children who subsequently receive a clinical diagnosis of hearing loss. (Pediatrics. 2016;137[1].) The authors of the report hope the lessons learned from the success of newborn hearing screening programs could be applied to early detection and intervention initiatives for critical congenital heart disease and other health conditions.​

Published: 8/25/2017 2:44:00 PM


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More Infants are Benefiting from Newborn Hearing Screenings

A CDC Morbidity and Mortality Weekly Report found more infants are receiving documented newborn hearing screening and early intervention services. (2017;66[33]:888.) National early hearing detection and intervention (EHDI) data showed that the percentage of newborns who had documented newborn hearing screening increased from 52 percent to over 97 percent between 2000 and 2014. From 2005 to 2014, documented enrollment in early intervention from 2005 to 2014 among newborns who received documented screening increased from 58 percent to 65 percent. The number of infants lost to follow-up reduced both overall and in selected states. For example, only 4.6 percent of infants who did not pass newborn hearing screening in Massachusetts in 2014 were lost to follow-up, and 85 percent of newborns with diagnosed hearing loss were documented to have received intervention services.

​Early diagnosis of hearing loss, starting with newborn screening, has been shown to reduce deficits in receptive and expressive language that occur in unscreened children who subsequently receive a clinical diagnosis of hearing loss. (Pediatrics. 2016;137[1].) The authors of the report hope the lessons learned from the success of newborn hearing screening programs could be applied to early detection and intervention initiatives for critical congenital heart disease and other health conditions.​

Published: 8/25/2017 2:44:00 PM


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Παρασκευή 25 Αυγούστου 2017

Human Frequency Following Responses to Vocoded Speech

imageObjectives: Vocoders offer an effective platform to simulate the effects of cochlear implant speech processing strategies in normal-hearing listeners. Several behavioral studies have examined the effects of varying spectral and temporal cues on vocoded speech perception; however, little is known about the neural indices of vocoded speech perception. Here, the scalp-recorded frequency following response (FFR) was used to study the effects of varying spectral and temporal cues on brainstem neural representation of specific acoustic cues, the temporal envelope periodicity related to fundamental frequency (F0) and temporal fine structure (TFS) related to formant and formant-related frequencies, as reflected in the phase-locked neural activity in response to vocoded speech. Design: In experiment 1, FFRs were measured in 12 normal-hearing, adult listeners in response to a steady state English back vowel /u/ presented in an unaltered, unprocessed condition and six sine-vocoder conditions with varying numbers of channels (1, 2, 4, 8, 16, and 32), while the temporal envelope cutoff frequency was fixed at 500 Hz. In experiment 2, FFRs were obtained from 14 normal-hearing, adult listeners in response to the same English vowel /u/, presented in an unprocessed condition and four vocoded conditions where both the temporal envelope cutoff frequency (50 versus 500 Hz) and carrier type (sine wave versus noise band) were varied separately with the number of channels fixed at 8. Fast Fourier Transform was applied to the time waveforms of FFR to analyze the strength of brainstem neural representation of temporal envelope periodicity (F0) and TFS-related peaks (formant structure). Results: Brainstem neural representation of both temporal envelope and TFS cues improved when the number of channels increased from 1 to 4, followed by a plateau with 8 and 16 channels, and a reduction in phase-locking strength with 32 channels. For the sine vocoders, peaks in the FFRTFS spectra corresponded with the low-frequency sine-wave carriers and side band frequencies in the stimulus spectra. When the temporal envelope cutoff frequency increased from 50 to 500 Hz, an improvement was observed in brainstem F0 representation with no change in brainstem representation of spectral peaks proximal to the first formant frequency (F1). There was no significant effect of carrier type (sine- versus noise-vocoder) on brainstem neural representation of F0 cues when the temporal envelope cutoff frequency was 500 Hz. Conclusions: While the improvement in neural representation of temporal envelope and TFS cues with up to 4 vocoder channels is consistent with the behavioral literature, the reduced neural phase-locking strength noted with even more channels may be because of the narrow bandwidth of each channel as the number of channels increases. Stronger neural representation of temporal envelope cues with higher temporal envelope cutoff frequencies is likely a reflection of brainstem neural phase-locking to F0-related periodicity fluctuations preserved in the 500-Hz temporal envelopes, which are unavailable in the 50-Hz temporal envelopes. No effect of temporal envelope cutoff frequency was seen for neural representation of TFS cues, suggesting that spectral side band frequencies created by the 500-Hz temporal envelopes did not improve neural representation of F1 cues over the 50-Hz temporal envelopes. Finally, brainstem F0 representation was not significantly affected by carrier type with a temporal envelope cutoff frequency of 500 Hz, which is inconsistent with previous results of behavioral studies examining pitch perception of vocoded stimuli.

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Hearing Threshold Shifts Among 11- to 35-Year-Olds With Early Hearing Impairment

imageObjectives: Data obtained from the clinical records of selected 11- to 35-year-olds with preadult onset hearing impairment were analyzed with 2 primary aims: (1) to determine the incidence of hearing threshold level (HTL) shift in this cohort and, (2) to examine the relationship between HTL shift, whole-of-life noise exposure, and other factors. Design: Cross-sectional cohort study. Retrospective HTL + survey data for a sample of 237 young Australians receiving hearing (re)habilitation services were obtained. From these data, two subsets, (A) n = 127 and (B) n = 79, were analyzed. Participants with risk factors for progressive hearing loss (other than noise exposure) were excluded from both subsets. Subset (A) additionally excluded cochlear implant recipients, and subset (B) excluded cases with diagnosis of hearing loss after age 5 years. Using subset (A) data, the differences between final (recent) and specified baseline (initial) HTLs at 250, 500, 1000, 2000, and 4000 Hz were calculated and three criteria for HTL shift were applied. Correlations between reported noise exposure and HTL shift were calculated (Mann–Whitney U test). Using subset (B) data, relationships between high frequency (HF) HTL shift and exposure, and other personal and extrinsic factors were examined (Cox Regression model). Survival analyses (Kaplan–Meier) were performed to reveal the temporal pattern of HF shift. The magnitude of HF shifts at 5, 10, and 15 years post initial (i.e., specified baseline) audiogram were also calculated. Results: For subset (A), HTL shift (≥15 dB any frequency, and/or ≥10 dB* at two adjacent frequencies) was observed in 46.5% of cases examined. HF shift (≥15 dB at 2000 and/or 4000 Hz; one or both ears) was observed in 33.1% of cases. There was no relationship between HTL shift and reported whole-of-life exposure. For subset (B), no relationship was found between HF shift and noise exposure, nor 9 of 10 personal or extrinsic covariates tested. HF shift was significantly associated with HTL ≥ 70 dB at 2000 and/or 4000 Hz at initial audiogram. Survival analysis also illustrated that HF shift was more frequent, and occurred earlier, when HF hearing loss was ≥70 dB at initial audiogram. Median HF shifts at 15 years after initial audiogram were in the magnitude of 5 to 10 dB, and at the 90th percentile were 25 to 30 dB. Conclusions: HTL shift was observed in almost 50% of cases without predisposing factors for progressive hearing loss. The magnitude of HF shift increased gradually over time. While no relationship was found between HTL shift and noise exposure, the interpretation of this finding is restrained by the small spread of whole-of-life noise exposures, within a relatively conservative range. Nevertheless, this is the first direct examination of the relationship between HTL shift and noise exposure in young people with preadult hearing impairment.

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Combined Electric and Acoustic Stimulation With Hearing Preservation: Effect of Cochlear Implant Low-Frequency Cutoff on Speech Understanding and Perceived Listening Difficulty

imageObjective: The primary objective of this study was to assess the effect of electric and acoustic overlap for speech understanding in typical listening conditions using semidiffuse noise. Design: This study used a within-subjects, repeated measures design including 11 experienced adult implant recipients (13 ears) with functional residual hearing in the implanted and nonimplanted ear. The aided acoustic bandwidth was fixed and the low-frequency cutoff for the cochlear implant (CI) was varied systematically. Assessments were completed in the R-SPACE sound-simulation system which includes a semidiffuse restaurant noise originating from eight loudspeakers placed circumferentially about the subject’s head. AzBio sentences were presented at 67 dBA with signal to noise ratio varying between +10 and 0 dB determined individually to yield approximately 50 to 60% correct for the CI-alone condition with full CI bandwidth. Listening conditions for all subjects included CI alone, bimodal (CI + contralateral hearing aid), and bilateral-aided electric and acoustic stimulation (EAS; CI + bilateral hearing aid). Low-frequency cutoffs both below and above the original “clinical software recommendation” frequency were tested for all patients, in all conditions. Subjects estimated listening difficulty for all conditions using listener ratings based on a visual analog scale. Results: Three primary findings were that (1) there was statistically significant benefit of preserved acoustic hearing in the implanted ear for most overlap conditions, (2) the default clinical software recommendation rarely yielded the highest level of speech recognition (1 of 13 ears), and (3) greater EAS overlap than that provided by the clinical recommendation yielded significant improvements in speech understanding. Conclusions: For standard-electrode CI recipients with preserved hearing, spectral overlap of acoustic and electric stimuli yielded significantly better speech understanding and less listening effort in a laboratory-based, restaurant-noise simulation. In conclusion, EAS patients may derive more benefit from greater acoustic and electric overlap than given in current software fitting recommendations, which are based solely on audiometric threshold. These data have larger scientific implications, as previous studies may not have assessed outcomes with optimized EAS parameters, thereby underestimating the benefit afforded by hearing preservation.

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Binaural Interaction Effects of 30–50 Hz Auditory Steady State Responses

imageObjectives: Auditory stimuli modulated by modulation frequencies within the 30 to 50 Hz region evoke auditory steady state responses (ASSRs) with high signal to noise ratios in adults, and can be used to determine the frequency-specific hearing thresholds of adults who are unable to give behavioral feedback reliably. To measure ASSRs as efficiently as possible a multiple stimulus paradigm can be used, stimulating both ears simultaneously. The response strength of 30 to 50Hz ASSRs is, however, affected when both ears are stimulated simultaneously. The aim of the present study is to gain insight in the measurement efficiency of 30 to 50 Hz ASSRs evoked with a 2-ear stimulation paradigm, by systematically investigating the binaural interaction effects of 30 to 50 Hz ASSRs in normal-hearing adults. Design: ASSRs were obtained with a 64-channel EEG system in 23 normal-hearing adults. All participants participated in one diotic, multiple dichotic, and multiple monaural conditions. Stimuli consisted of a modulated one-octave noise band, centered at 1 kHz, and presented at 70 dB SPL. The diotic condition contained 40 Hz modulated stimuli presented to both ears. In the dichotic conditions, the modulation frequency of the left ear stimulus was kept constant at 40 Hz, while the stimulus at the right ear was either the unmodulated or modulated carrier. In case of the modulated carrier, the modulation frequency varied between 30 and 50 Hz in steps of 2 Hz across conditions. The monaural conditions consisted of all stimuli included in the diotic and dichotic conditions. Results: Modulation frequencies ≥36 Hz resulted in prominent ASSRs in all participants for the monaural conditions. A significant enhancement effect was observed (average: ~3 dB) in the diotic condition, whereas a significant reduction effect was observed in the dichotic conditions. There was no distinct effect of the temporal characteristics of the stimuli on the amount of reduction. The attenuation was in 33% of the cases >3 dB for ASSRs evoked with modulation frequencies ≥40 Hz and 50% for ASSRs evoked with modulation frequencies ≤36 Hz. Conclusions: Binaural interaction effects as observed in the diotic condition are similar to the binaural interaction effects of middle latency responses as reported in the literature, suggesting that these responses share a same underlying mechanism. Our data also indicated that 30 to 50 Hz ASSRs are attenuated when presented dichotically and that this attenuation is independent of the stimulus characteristics as used in the present study. These findings are important as they give insight in how binaural interaction affects the measurement efficiency. The 2-ear stimulation paradigm of the present study was, for the most optimal modulation frequencies (i.e., ≥40 Hz), more efficient than a 1-ear sequential stimulation paradigm in 66% of the cases.

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Pre- and Postoperative Binaural Unmasking for Bimodal Cochlear Implant Listeners

imageObjectives: Cochlear implants (CIs) are increasingly recommended to individuals with residual bilateral acoustic hearing. Although new hearing-preserving electrode designs and surgical approaches show great promise, CI recipients are still at risk to lose acoustic hearing in the implanted ear, which could prevent the ability to take advantage of binaural unmasking to aid speech recognition in noise. This study examined the tradeoff between the benefits of a CI for speech understanding in noise and the potential loss of binaural unmasking for CI recipients with some bilateral preoperative acoustic hearing. Design: Binaural unmasking is difficult to evaluate in CI candidates because speech perception in noise is generally too poor to measure reliably in the range of signal to noise ratios (SNRs) where binaural intelligibility level differences (BILDs) are typically observed (

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