Congenital diaphragmatic hernia: the good, the bad, and the tough

Abstract

Objectives

We aim to determine factors that are associated with better outcomes of CDH patients.

Methods

A retrospective review was performed on all CDH patients admitted to our institution between 2003 and 2016. This study was performed at a single institution which has a fetal care center. Patients admitted with CDH with at least 1-year follow-up during the analysis were included in the study.

Results

Twenty-six (13.8%) patients had a hernia sac, 124 (59%) patients had liver herniation, and 56 (25.1%) patients had an accompanying syndrome. Overall survival to discharge was 73.1% while overall survival to date was 69.5%. The presence of a hernia sac, liver herniation, and accompanying syndromes showed as independent predictors influencing the survival, B 1.968, p = 0.04, OR 7.158, 95% CI 0.907–56.485, B − 1.178, p = 0.01, OR 3.932, 95% CI 1.798–8.602 and B − 1.032, p = 0.05, OR 2.795, 95% CI 0.976–7.764, respectively.

Conclusion

In our CDH cohort, the presence of a hernia sac was proven to be associated with better outcomes, while thoracic herniation of the liver was associated with worse outcomes. The accompanying syndromes although being more difficult to manage had a little effect on the outcome of the disease itself.

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