A woman in China has been reported to have sudden-onset reverse-slope hearing loss (RSHL), a rare condition that results in an inability to hear low-pitch noises. Prior to the onset, this woman suffered from nausea and tinnitus the night before. When she woke up the following morning, she could not hear her boyfriend or the male patients at the hospital where she sought help. Her case drew attention to RSHL, also known as low-frequency hearing loss and considered a subtype of idiopathic sudden hearing loss. It shows up as the reverse of the ski-slope hearing loss on an audiogram, and affects 3,000 people in the United States and Canada combined (http://bit.ly/2sCWPTv). Genetic conditions, including Wolfram syndrome, Mondini dysplasia, and inheritance through a dominant gene, have all been identified as sources of RSHL. Diseases that affect hair cells such as sudden hearing loss, Ménière's disease, and viral infection and changes in the pressure of the endolymph have also been linked to RSHL. Research found that this type of hearing loss has a better prognosis than other types of hearing loss, and the 10-year prognosis can be predicted by the clinical course (initial therapy and hearing fluctuations) during the first year after onset (Otolaryngol Head Neck Surg 2010;142[4]:565).
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