Publication date: Available online 30 March 2019Source: Allergology InternationalAuthor(s): Kiwako Yamamoto-Hanada, Limin Yang, Mayako Saito-Abe, Miori Sato, Yusuke Inuzuka, Kenji Toyokuni, Koji Nishimura, Makoto Irahara, Fumi Ishikawa, Yumiko Miyaji, Tatsuki Fukuie, Masami Narita, Hirohisa Saito, Yukihiro Ohya
Sat Mar 30, 2019 15:39
Publication date: April 2019Source: Allergology International, Volume 68, Issue 2Author(s): Koichiro Asano, Kenji Izuhara
Fri Mar 29, 2019 12:43
Publication date: Available online 29 March 2019Source: Allergology InternationalAuthor(s): Tetsuharu Manabe, Sakura Sato, Noriyuki Yanagida, Noriko Hayashi, Makoto Nishino, Kyohei Takahashi, Ken-ichi Nagakura, Tomoyuki Asaumi, Kiyotake Ogura, Motohiro Ebisawa
Fri Mar 29, 2019 12:43
AbstractAnthony Barrington (Barry) Kay PhD, DSc; FRCPE, FRCP, FRCPath, FMedSci; FRSE, grew up in Northamptonshire, England and was educated at the University of Edinburgh (MD) and the University of Cambridge (PhD). He trained under the guidance of earlier Legends in the field, including Robin Coombs (Cambridge) and K. Frank Austen (Harvard). In turn, Barry Kay has been an important guiding figure in the development of clinical and experimental allergy/immunology in the UK, and globally, training...
Fri Mar 29, 2019 11:50
Publication date: Available online 30 March 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): S. Mehr, Terri Brown-Whitehorn
Sat Mar 30, 2019 17:01
Immunoglobulin E (IgE) is the treatment target of omalizumab, a monoclonal antibody indicated in the treatment of severe allergic asthma. Long-term variability of serum total IgE (sIgEtot) in asthmatics remains p...
Fri Mar 29, 2019 02:00
Severe anaphylaxis after pelvic examination: a case report of dual latex and chlorhexidine allergies
Natural rubber latex and chlorhexidine have previously been identified as causative substances in perioperative anaphylaxis. A pelvic examinations is generally considered noninvasive, however, this procedure i...
Fri Mar 29, 2019 02:00
AbstractBackgroundThe precise mechanism involved in the acquisition of the IL‐17+ profile of γδT cells, the ligands responsible for this change, and whether this default is acquired during intrathymic maturation need to be elucidated.ObjectiveThis study aimed to evaluate whether IL‐17‐producing γδT cells are present in the airways of tolerant offspring from allergen‐sensitized mothers and the possible implication of maternal IgG in the generation of these cells.MethodsFemale mice were immunized...
Sun Mar 31, 2019 15:42
Thu Mar 28, 2019 13:42
Thu Mar 28, 2019 13:42
The cover image is based on the Original Article Germination of pollen grains in the oesophagus of individuals with eosinophilic oesophagitis by Alicia Armentia et al, DOI: 10.1111/cea.13312.
Thu Mar 28, 2019 13:42
Thu Mar 28, 2019 13:42
Thu Mar 28, 2019 13:42
Purpose of review PFAS shows various cross-reactivities with antigens because of the area in which the patient resides and dietary habits, and progress in component allergen analysis in recent years has clarified the pathogenesis. This review describes newly identified findings for antigens involved in PFAS. Recent findings We describe recent findings for PR-10 family, profilin and LTP, as known major antigens for PFAS. Microarrays of allergen components have significantly improved the ability...
Thu Mar 28, 2019 02:00
This study identifies RAGE as an essential component of type 2 cytokine signal transduction. RAGE neutralization may represent a novel combinatorial treatment for severe asthmatics with type 2-high phenotype.
Sat Mar 30, 2019 02:00
The NF-kB signaling pathways play a key-role in various cell processes related to host immunity. The last few years have seen an explosion of disorders associated with NF-kB components, from core members of the canonical and non-canonical cascades, to adaptor protein and ubiquitination-related enzymes. Disease phenotypes have extended beyond susceptibility to infections, and include autoimmunity, lympho-proliferation, atopy and inflammation. Concurrently, studies are unveiling a tightly-regulated...
Sat Mar 30, 2019 02:00
Functional genomics of CDHR3 confirms its role in HRV-C infection and childhood asthma exacerbations
Publication date: Available online 29 March 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Jamie L. Everman, Satria Sajuthi, Benjamin Saef, Cydney Rios, Ari M. Stoner, Mari Numata, Donglei Hu, Celeste Eng, Sam Oh, Jose Rodriguez-Santana, Eszter K. Vladar, Dennis R. Voelker, Esteban G. Burchard, Max A. SeiboldAbstractBackgroundResearch in transformed, immortalized cell lines indicates the cadherin-related family member 3 (CDHR3) protein serves as a receptor for human rhinovirus C...
Fri Mar 29, 2019 12:25
